Journal of Emergency Medicine最新文献

筛选
英文 中文
A Spinal Tap Does Not Require Skin Markings 脊柱穿刺不需要皮肤标记
IF 1.5 4区 医学
Journal of Emergency Medicine Pub Date : 2024-06-14 DOI: 10.1016/j.jemermed.2024.02.009
Peyton J. Ware BS , Emmanuelle C. Issa BS , Paula Bitange BA , Garrett J. Cooper BS , Victoria Galea MD , Deena I. Bengiamin MD , Timothy P. Young MD
{"title":"A Spinal Tap Does Not Require Skin Markings","authors":"Peyton J. Ware BS , Emmanuelle C. Issa BS , Paula Bitange BA , Garrett J. Cooper BS , Victoria Galea MD , Deena I. Bengiamin MD , Timothy P. Young MD","doi":"10.1016/j.jemermed.2024.02.009","DOIUrl":"https://doi.org/10.1016/j.jemermed.2024.02.009","url":null,"abstract":"","PeriodicalId":16085,"journal":{"name":"Journal of Emergency Medicine","volume":null,"pages":null},"PeriodicalIF":1.5,"publicationDate":"2024-06-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141325214","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Beirut Port Blast 2020: New Lessons Learned in Mass Casualty Incident Management in the Emergency Department 2020 年贝鲁特港口爆炸事件:急诊科处理大规模伤亡事件的新经验
IF 1.5 4区 医学
Journal of Emergency Medicine Pub Date : 2024-06-14 DOI: 10.1016/j.jemermed.2024.03.006
Evan Avraham Alpert MD , Ahmed Nama MD , Daniel Trotzky MD, MHA , Tzachi Slutsky MD , Betzalel E. Reich MD , J. Ari Greenwald MD , Barry Hahn MD , Joseph Offenbacher MD
{"title":"Beirut Port Blast 2020: New Lessons Learned in Mass Casualty Incident Management in the Emergency Department","authors":"Evan Avraham Alpert MD , Ahmed Nama MD , Daniel Trotzky MD, MHA , Tzachi Slutsky MD , Betzalel E. Reich MD , J. Ari Greenwald MD , Barry Hahn MD , Joseph Offenbacher MD","doi":"10.1016/j.jemermed.2024.03.006","DOIUrl":"https://doi.org/10.1016/j.jemermed.2024.03.006","url":null,"abstract":"","PeriodicalId":16085,"journal":{"name":"Journal of Emergency Medicine","volume":null,"pages":null},"PeriodicalIF":1.5,"publicationDate":"2024-06-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141325211","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Emergency Department Screening and Interventions for Adolescents With Substance Use: A Narrative Review 急诊科对青少年药物使用的筛查和干预:叙述性综述
IF 1.2 4区 医学
Journal of Emergency Medicine Pub Date : 2024-06-10 DOI: 10.1016/j.jemermed.2024.05.012
{"title":"Emergency Department Screening and Interventions for Adolescents With Substance Use: A Narrative Review","authors":"","doi":"10.1016/j.jemermed.2024.05.012","DOIUrl":"10.1016/j.jemermed.2024.05.012","url":null,"abstract":"<div><h3>Background</h3><p>Adolescent substance use is a growing public health concern, particularly given rising mortality rates from drug overdose deaths. The emergency department (ED) provides a unique opportunity to screen adolescents for substance use and provide brief interventions and linkage to care.</p></div><div><h3>Objective of the Review</h3><p>This article provides a narrative review of the current evidence for ED screening and brief interventions for adolescents with substance use and identifies important opportunities, challenges, and areas for future research.</p></div><div><h3>Discussion</h3><p>There are several validated substance use screening and assessment tools for use with adolescents that can be implemented into ED screening programs. Brief motivational interviewing interventions may reduce alcohol use, but evidence for reductions of other substances is limited due to insufficient research. Both screening and interventions are feasible and acceptable in the ED setting with the appropriate resources. Increased training and the use of emerging technology can provide emergency physicians with opportunities to incorporate these tools into practice to when treating adolescents. Linkage to outpatient care for adolescents with substance use is understudied. The research on adult patient ED interventions and linkage to care is more robust and can provide insights for future ED studies among adolescents.</p></div><div><h3>Conclusion</h3><p>ED-based adolescent substance use screening and interventions are necessary, feasible, and acceptable, but understudied. Future studies, focusing on optimizing ED interventions and linkage to care, are important next steps in determining the best care for adolescents with substance use who present to the ED.</p></div>","PeriodicalId":16085,"journal":{"name":"Journal of Emergency Medicine","volume":null,"pages":null},"PeriodicalIF":1.2,"publicationDate":"2024-06-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141390087","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Investigation of the Relationship Between the Measured Alpha Angle in Capnography and Readmission Within Thirty Days in Chronic Obstructive Pulmonary Disease Patients Who Presented to the Emergency Department 研究急诊科慢性阻塞性肺病患者在气管造影中测量到的阿尔法角与三十天内再入院之间的关系。
IF 1.2 4区 医学
Journal of Emergency Medicine Pub Date : 2024-06-04 DOI: 10.1016/j.jemermed.2024.05.013
Murat Tuncekin , Asim E. Ozbek , Emre Sanci (Şancı) , Fatma Emre Turan Tasolar , Huseyin C. Halhalli
{"title":"Investigation of the Relationship Between the Measured Alpha Angle in Capnography and Readmission Within Thirty Days in Chronic Obstructive Pulmonary Disease Patients Who Presented to the Emergency Department","authors":"Murat Tuncekin ,&nbsp;Asim E. Ozbek ,&nbsp;Emre Sanci (Şancı) ,&nbsp;Fatma Emre Turan Tasolar ,&nbsp;Huseyin C. Halhalli","doi":"10.1016/j.jemermed.2024.05.013","DOIUrl":"10.1016/j.jemermed.2024.05.013","url":null,"abstract":"<div><h3>Background</h3><p>Individuals with chronic obstructive pulmonary disease (COPD) constitute a significant portion of patients who present to the emergency department with dyspnea. However, there is no ideal method for predicting mortality or making hospitalization decisions in the emergency department (ED). In this regard, objective findings are needed for these patients. Since there are no objective findings regarding the hospitalization decision, there may be an increase in the re-admission rate of patients who needed hospitalization but were decided to be discharged<span>.</span> Side-stream end-tidal carbon dioxide (EtCO<sub>2</sub>) measurements offer a non-invasive, easy-to-interpret, quickly accessible, and reproducible method that can be applied at the bedside.</p></div><div><h3>Objectives</h3><p>The aim of this study was to evaluate the relationship between the alpha angle values obtained by capnography and readmission rates within 30 days for patients experiencing COPD exacerbations who presented to the ED with dyspnea and were discharged after treatment.</p></div><div><h3>Methods</h3><p>In this study, we studied with 130 participants presented to the emergency department of a tertiary care university hospital with dyspnea, who are &gt;18 y. Forty patients were excluded after evaluation for eligibility for the study. Thus, the data of 90 patients included were analyzed. We obtained alpha angle and EtCO<sub>2</sub> values for all patients at the time of admission and also after treatment. The primary outcome measure of the study was the relationship between the patients’ readmission situations within 30 days of the alpha angle measurements. The secondary outcome measure was the association between patients’ EtCO<sub>2</sub> values ​​and readmission within 30 days.</p></div><div><h3>Results</h3><p>It was observed that both the pretreatment alpha angle values and the posttreatment alpha angle variables were statistically significant in predicting the readmission of the patients within 30 days (<em>p</em> = 0.001, <em>p</em> = 0.003)</p></div><div><h3>Conclusion</h3><p>The results of this study show that alpha angle values measured for patients with COPD who present to the ED with the complaint of dyspnea may be used to predict readmission.</p></div>","PeriodicalId":16085,"journal":{"name":"Journal of Emergency Medicine","volume":null,"pages":null},"PeriodicalIF":1.2,"publicationDate":"2024-06-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142154352","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Emergency Ultrasound Unveils Intermediate-High Risk Saddle Pulmonary Embolism with Extensive Bilateral Clot Burden, Masquerading as Micturition Syncope: A Case Report 急诊超声波检查发现中高危鞍区肺栓塞,双侧血块广泛堆积,伪装成排尿性晕厥--病例报告
IF 1.5 4区 医学
Journal of Emergency Medicine Pub Date : 2024-06-01 DOI: 10.1016/j.jemermed.2024.01.018
M. Townsend Reeves MD , Harjeev Lahil MD , Aaron Gold MD , Mauricio Danckers MD, FCCP , Laurence Dubensky MD, FACEP , Todd L. Slesinger MD, FACEP, FCCM, FCCP, FAAEM
{"title":"Emergency Ultrasound Unveils Intermediate-High Risk Saddle Pulmonary Embolism with Extensive Bilateral Clot Burden, Masquerading as Micturition Syncope: A Case Report","authors":"M. Townsend Reeves MD ,&nbsp;Harjeev Lahil MD ,&nbsp;Aaron Gold MD ,&nbsp;Mauricio Danckers MD, FCCP ,&nbsp;Laurence Dubensky MD, FACEP ,&nbsp;Todd L. Slesinger MD, FACEP, FCCM, FCCP, FAAEM","doi":"10.1016/j.jemermed.2024.01.018","DOIUrl":"10.1016/j.jemermed.2024.01.018","url":null,"abstract":"<div><h3>Background</h3><p>Isolated syncope as the manifestation of pulmonary embolism (PE) is a rare and diagnostically challenging presentation that often leads to delayed or missed diagnosis, increasing morbidity and mortality. In spite of emphasizing cardiovascular etiologies of syncope, current guidelines offer essentially no guidance in establishing a diagnostic workup for PE in these patients. By performing bedside echocardiography, emergency physicians can accurately identify concerning features suggestive of PE in patients with syncope.</p></div><div><h3>Case Report</h3><p>A 78-year-old man, receiving ertapenem via a peripherally inserted central catheter for treatment of extended spectrum β-lactamase urinary tract infection, presented to the emergency department for isolated syncope with collapse while urinating. Arriving asymptomatic with normal vital signs and a benign physical examination, a presumptive diagnosis of micturition syncope was made. However, subtle vital sign changes on reassessment prompted performance of a point-of-care echocardiogram, which revealed signs of right heart strain. A computed tomography angiogram confirmed a saddle PE with extensive bilateral clot burden. Catheter-directed thrombectomy was performed via interventional radiology, with successful removal of pulmonary emboli.</p></div><div><h3>Why Should an Emergency Physician Be Aware of This?</h3><p>Pulmonary embolism presenting as isolated syncope represents a daunting diagnostic dilemma, as emergency physicians may not consider it, or anchor on more benign etiologies of syncope. Although lacking sufficient sensitivity to rule out PE, point-of-care echocardiography to evaluate for signs of right heart strain can quickly and effectively point toward the diagnosis, while also assessing for other emergent cardiovascular causes of syncope. Given the lack of evidence-based guidance concerning PE presenting as syncope, bedside echocardiography should be highly considered as a part of the emergency physician's diagnostic workup, especially in patients with abnormal vital signs.</p></div>","PeriodicalId":16085,"journal":{"name":"Journal of Emergency Medicine","volume":null,"pages":null},"PeriodicalIF":1.5,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139470219","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Abdominal Compartment Syndrome Secondary to Bulimia Nervosa: A Case Report and Systematic Review of Published Cases 继发于神经性贪食症的腹腔隔室综合征:病例报告和已发表病例的系统回顾
IF 1.5 4区 医学
Journal of Emergency Medicine Pub Date : 2024-06-01 DOI: 10.1016/j.jemermed.2024.01.014
Nifesimi Olojede MD , Emanuel Cassimatis MD , Henry Tsao FACEM, PhD, MBBS
{"title":"Abdominal Compartment Syndrome Secondary to Bulimia Nervosa: A Case Report and Systematic Review of Published Cases","authors":"Nifesimi Olojede MD ,&nbsp;Emanuel Cassimatis MD ,&nbsp;Henry Tsao FACEM, PhD, MBBS","doi":"10.1016/j.jemermed.2024.01.014","DOIUrl":"10.1016/j.jemermed.2024.01.014","url":null,"abstract":"<div><h3>Background</h3><p>Abdominal compartment syndrome (ACS) is typically attributed to critically unwell patients with trauma, burns, post surgery, and massive ascites. A rare but fatal cause of ACS is bulimia nervosa (BN), which is an eating disorder characterized by bingeing, followed by methods to avoid weight gain, including purging.</p></div><div><h3>Case Report</h3><p>We present a case of a 20-year-old woman who presented with abdominal pain and distension after consuming a large quantity of food the previous night and was unable to purge. She was initially managed conservatively and discharged home, but returned subsequently on the same day with clinical features of ACS secondary to acute gastric distension. Decompression resulted in life-threatening reperfusion injury with critical electrolyte abnormalities and fatal cardiac arrest in the operating theatre.</p></div><div><h3>Why Should an Emergency Physician Be Aware of This?</h3><p>A systematic review of the literature found only 11 case reports of ACS secondary to BN, of which only 6 patients survived due to early diagnosis and decompression. Inability to purge and lower limb ischemia appeared to be associated with increased mortality. As BN is a common emergency presentation, the case and systematic review highlights the need to consider ACS as a potentially life-threatening complication of binge eating, particularly when there is unsuccessful purging.</p></div>","PeriodicalId":16085,"journal":{"name":"Journal of Emergency Medicine","volume":null,"pages":null},"PeriodicalIF":1.5,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139508943","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Cost of Stethoscope Hygiene vs. the Cost of Hygiene Failure 听诊器卫生的代价与卫生失败的代价
IF 1.5 4区 医学
Journal of Emergency Medicine Pub Date : 2024-06-01 DOI: 10.1016/j.jemermed.2024.03.026
W. Frank Peacock MD, FACEP, FACC, FESC
{"title":"The Cost of Stethoscope Hygiene vs. the Cost of Hygiene Failure","authors":"W. Frank Peacock MD, FACEP, FACC, FESC","doi":"10.1016/j.jemermed.2024.03.026","DOIUrl":"https://doi.org/10.1016/j.jemermed.2024.03.026","url":null,"abstract":"<div><h3>Background</h3><p>Stethoscopes, well established as vectors, are recommended to be cleaned by alcohol swab scrubbing for 60 seconds. The new 2024 CDC guidelines mandate stethoscope cleaning between every patient. Unfortunately, guideline failure is poorly described, especially in immunocompromised cancer patients. We thus performed a model examining the expense of stethoscope hygiene using the probabilities and costs of stethoscope infection transmission from 2 well described pathogens; Methicillin Resistant Staphylococcus Aureus (MRSA) and Clostridioides difficile infection (CDI), in both immunocompromised and immunocompetent patients.</p></div><div><h3>Methods</h3><p>We performed an economic analysis of pathogen transmission costs and consequences in immunocompromised and immunocompetent ED patients. Variables were defined as auscultations/day in a medium sized ED =90 (30/physician, 3 physicians/24 hours), stethoscope cleaning time =60 seconds, annual ED physician salary =$352,000.00, published stethoscope contamination rates of MRSA and CDI =7.4% and 5%, respectively, and published hospital acquired infection costs for MRSA and CDI =$38,561.00 and $24,205, respectively. The immunocompromised rate was defined as 2.7%, and the estimated probability of infection occurring after exposure in immunocompetent and immunocompromised patients is analyzed by ranges of 1-3% and 10-30%, respectively.</p></div><div><h3>Results</h3><p>Using the above definitions provides an estimation of 32,850 auscultations/year/ED, which equates to 547 annual hours of emergency physician stethoscope cleaning; prorated by salary, results in an annual ED cost of $115,940.00/yr.</p></div><div><h3>Conclusions</h3><p>Cleaning personal stethoscope costs $115,940.00/yr, but its failure may cost up to $4.98 million/yr/hospital.</p></div>","PeriodicalId":16085,"journal":{"name":"Journal of Emergency Medicine","volume":null,"pages":null},"PeriodicalIF":1.5,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141243278","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Paramedics as Researchers: A Systematic Review of Paramedic Perspectives of Engaging in Research Activity From Training to Practice 辅助医务人员作为研究人员:对辅助医务人员从培训到实践参与研究活动的观点进行系统审查
IF 1.5 4区 医学
Journal of Emergency Medicine Pub Date : 2024-06-01 DOI: 10.1016/j.jemermed.2024.01.008
Jessica Runacres PhD , Hannah Harvey PhD , Sam O'Brien BSc , Amy Halck BTech
{"title":"Paramedics as Researchers: A Systematic Review of Paramedic Perspectives of Engaging in Research Activity From Training to Practice","authors":"Jessica Runacres PhD ,&nbsp;Hannah Harvey PhD ,&nbsp;Sam O'Brien BSc ,&nbsp;Amy Halck BTech","doi":"10.1016/j.jemermed.2024.01.008","DOIUrl":"10.1016/j.jemermed.2024.01.008","url":null,"abstract":"<div><h3>Background</h3><p>The need for a stronger evidence-base in paramedicine has precipitated a rapid development of prehospital research agendas. Paramedics are increasingly involved in research, leading to changes in their role. Yet, the integration of research responsibilities has proven to be challenging, resulting in varying attitudes and levels of engagement.</p></div><div><h3>Objective</h3><p>This systematic review aimed to explore paramedics’ views and experiences of research as researchers during training and within practice.</p></div><div><h3>Methods</h3><p>A systematic search was performed across six databases. Qualitative empirical peer-reviewed articles that discussed paramedic perspectives on engaging with research activity were included. Of 10,594 articles identified initially, 11 were included in the final synthesis after quality appraisal. Data were extracted and subjected to narrative synthesis.</p></div><div><h3>Results</h3><p>The following four themes were identified: motivation to engage, moral dilemmas, structural issues within the profession, and reflections on trial involvement. Attitudes toward research, understanding of related concepts, and the drive for patient benefit were interwoven core issues.</p></div><div><h3>Conclusions</h3><p>Research was highly valued when links to patient benefit were obvious, however, this review highlights some cultural resistance to research, particularly regarding informed consent and changes to standard practice. Paramedic research methods training should provide structured opportunities to explore concerns and emphasize the role of research in developing a high-quality evidence base to underpin safe practice. Currently, there is inadequate organizational support for paramedics to engage effectively in research activity, with minimal allocations of time, training, and remuneration. Without properly integrating research activity into the paramedic role, their capacity to engage with research activity is limited.</p></div>","PeriodicalId":16085,"journal":{"name":"Journal of Emergency Medicine","volume":null,"pages":null},"PeriodicalIF":1.5,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S073646792400009X/pdfft?md5=2046f7f31436291c35e661dbf26b16a0&pid=1-s2.0-S073646792400009X-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139455079","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Finding the Balance: The Point-of-Care Ultrasound Diagnosis of Pseudoaneurysm 找到平衡:假性动脉瘤的护理点超声诊断
IF 1.5 4区 医学
Journal of Emergency Medicine Pub Date : 2024-06-01 DOI: 10.1016/j.jemermed.2024.01.011
Terrence D. Habiyaremye MD, Alyssa C. Alloy MD, Ryan C. Gibbons MD
{"title":"Finding the Balance: The Point-of-Care Ultrasound Diagnosis of Pseudoaneurysm","authors":"Terrence D. Habiyaremye MD,&nbsp;Alyssa C. Alloy MD,&nbsp;Ryan C. Gibbons MD","doi":"10.1016/j.jemermed.2024.01.011","DOIUrl":"10.1016/j.jemermed.2024.01.011","url":null,"abstract":"<div><p>A 49-year-old male with history of intravenous drug use presented to the Emergency Department with localized right arm swelling that has been slowly growing for months. On physical exam, there was a golf ball sized mass in the right antecubital fossa without overlying skin changes and no neurovascular deficits in the distal extremity. Point-of-care ultrasound (POCUS) was performed utilizing a water bath with visualization of bidirectional swirling in a round cavity adjacent to the brachial artery. Aneurysms are abnormal focal dilations that result from vascular wall defects. Ultrasound has been reported to have 94% sensitivity and 97% specificity for diagnosis of pseudoaneurysms. On color doppler ultrasound, pseudoaneurysm is characterized by the pathognomonic “yin-yang” sign. In the case of the 49-year-old male with a right antecubital mass and history of IVDU, the proposed mechanism of injury was trauma to the arterial wall secondary to auto-injection. POCUS has been found to improve identification of abscesses and its incorporation in patient evaluation can guide clinical management, prevent unwanted iatrogenic exsanguination, and determine whether there is a need for urgent vascular surgery intervention, particularly in high-risk patients.</p></div>","PeriodicalId":16085,"journal":{"name":"Journal of Emergency Medicine","volume":null,"pages":null},"PeriodicalIF":1.5,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139476830","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
An adjunct bio-array that rapidly differentiates viral from bacterial sources can improve quality of care in Oncology patients presenting to Emergency Departments (EDs) with respiratory illnesses 快速区分病毒和细菌来源的辅助生物芯片可提高因呼吸道疾病到急诊科(ED)就诊的肿瘤患者的护理质量
IF 1.5 4区 医学
Journal of Emergency Medicine Pub Date : 2024-06-01 DOI: 10.1016/j.jemermed.2024.03.030
David Robinson MD , Carolyn Gardiner MD , Jacqueline Furbacher MD , Michael Vu MD , Dacia Ticas MD , Carrie Bakunas MD , Neomi Sepulveda BS , Joseph Boyle BSN , Benjamin Karfunkle MD
{"title":"An adjunct bio-array that rapidly differentiates viral from bacterial sources can improve quality of care in Oncology patients presenting to Emergency Departments (EDs) with respiratory illnesses","authors":"David Robinson MD ,&nbsp;Carolyn Gardiner MD ,&nbsp;Jacqueline Furbacher MD ,&nbsp;Michael Vu MD ,&nbsp;Dacia Ticas MD ,&nbsp;Carrie Bakunas MD ,&nbsp;Neomi Sepulveda BS ,&nbsp;Joseph Boyle BSN ,&nbsp;Benjamin Karfunkle MD","doi":"10.1016/j.jemermed.2024.03.030","DOIUrl":"https://doi.org/10.1016/j.jemermed.2024.03.030","url":null,"abstract":"<div><h3>Background</h3><p>Oncology patients presenting to EDs with acute respiratory illnesses (ARI) require a broad workup and early treatment due to risk of underlying infection and immunocompromised status. Early antibiotic administration is often required as determining a nonbacterial source is time consuming. A novel host bio-array developed to rapidly differentiate bacterial from viral sources could improve ED resource utilization, reduce unnecessary antibiotics, and increase healthcare quality.</p></div><div><h3>Methods</h3><p>An IRB approved subject on multiple immunosuppressants presents with ARI and positive SIRS criteria. The MeMed BV® (BV) is an FDA approved rapid immunoassay that reports a computationally integrated score (0-100) of three host proteins (TNF-related apoptosis-inducing ligand (TRAIL), interferon gamma-induced protein 10 (IP-10), and C-reactive protein (CRP). The BV score and ED standard of care tests were obtained in a modified ED sepsis protocol (mEDSP). Scores above 65 are associated with bacterial infections, while scores below 10 are associated with viral infections. Cost of laboratory, radiology, professional and facilities fees (room charges, nursing, and ancillaries) were summed for the admission. Investigators received three surveys to: (1) establish pretest probability of disease, (2) determine posttest probability after receiving BV results, (3) query what resources might be withheld or changed if presented with the BV test results early.</p></div><div><h3>Results</h3><p>The BV reported a ‘0’ value (viral source) within 20 minutes. Further testing confirmed no bacterial source of infection. An adjudicated cost and resource review of the mEDSP and admission revealed a potential reduction of unnecessary antibiotics by 59%, lab testing by 24.2%, and overall costs by 23.2%. Admission time could have been reduced by 24 hours (43%). Furthermore, the ED physician was amenable to changing care based on this test.</p></div><div><h3>Conclusion</h3><p>Significant improvement in resource utilization and greater quality was identified with early identification of nonbacterial sources in ARI in the ED. Adjunct biomarkers differentiating viral from other sources can improve quality and resource utilization when deployed early in the ED. Further trials in the Emergency Oncology realm are necessary.</p></div>","PeriodicalId":16085,"journal":{"name":"Journal of Emergency Medicine","volume":null,"pages":null},"PeriodicalIF":1.5,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141240967","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
0
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
相关产品
×
本文献相关产品
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信