Adrianna Vaskas BS , Kyle Marshall MD , Ria Garg MD , Ciaran Fisher BS , Cindi L. Bower-Stout BSN, RN , Muzna Hussain MD , Martin E. Matsumura MD
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引用次数: 0
Abstract
Background
Contemporary evaluation of chest pain (CP) utilizes a high-sensitivity troponin (hsTn) accelerated diagnostic protocol (ADP). Whether the addition of a bioclinical risk score such as the HEART score improves performance of a hsTn ADP is not clear.
Objectives
To determine the effect of an automated best practice alert (BPA) that guided capture of the HEART score on emergency department (ED) discharge decision-making and outcomes when added to a hsTn ADP.
Methods
Retrospective cohort study of patients evaluated for CP in a 6 month period before and 10-month period following launch of a HEART score BPA in May 2022. Discharge percentages and 30-day major adverse cardiac event (MACE) rates were determined for the pre- vs. post-BPA cohort and stratified by both peak hsTnT value and HEART score.
Results
Compared to the pre-BPA cohort (n = 4438), post-BPA (n = 6794) with a completed HEART score had a higher rate of ED discharge (5.5% vs. 3.6%, p < 0.001). Patients with low (≤3) risk HEART scores had significantly lower (1.6% vs. 0.6%, p = 0.001) and patients with high-risk scores had significantly higher (1.6% vs. 6.6%, p < 0.001) rates of 30-day MACE vs. pre-BPA. The relationship of HEART score to MACE had the most discriminatory power in patients with peak hsTnT 12/51 ng/dL (3.9% vs. 6.7%, p < 0.028).
Conclusion
The addition of a HEART score BPA to a hsTnT ADP was associated with a higher rate of discharge and improved risk stratification of 30-day MACE among patients for whom a discharge disposition was made, particularly among patients with moderate elevations (12–51 ng/dL) of hsTnT.
背景:当代胸痛(CP)的评估采用高灵敏度肌钙蛋白(hsTn)加速诊断方案(ADP)。生物临床风险评分(如HEART评分)的加入是否能提高hsTn ADP的性能尚不清楚。目的:确定在加入hsTn ADP后,指导HEART评分采集的自动最佳实践警报(BPA)对急诊科(ED)出院决策和结果的影响。方法回顾性队列研究在2022年5月推出心脏评分BPA之前6个月和之后10个月进行CP评估的患者。通过hsTnT峰值值和HEART评分对bpa前后的患者进行分层,并确定其出院百分比和30天主要心脏不良事件(MACE)发生率。结果与bpa前队列(n = 4438)相比,bpa后(n = 6794)完成HEART评分的ED出院率更高(5.5% vs. 3.6%, p <;0.001)。低危(≤3)患者的HEART评分显著降低(1.6% vs. 0.6%, p = 0.001),高危患者的HEART评分显著升高(1.6% vs. 6.6%, p <;0.001) 30天MACE与bpa前的比率。在hsTnT峰值为12/51 ng/dL的患者中,HEART评分与MACE的关系最具歧视性(3.9% vs. 6.7%, p <;0.028)。结论:在hsTnT ADP中加入心脏评分BPA与出院率升高和30天MACE风险分层改善有关,特别是在hsTnT中度升高(12-51 ng/dL)的患者中。
期刊介绍:
The Journal of Emergency Medicine is an international, peer-reviewed publication featuring original contributions of interest to both the academic and practicing emergency physician. JEM, published monthly, contains research papers and clinical studies as well as articles focusing on the training of emergency physicians and on the practice of emergency medicine. The Journal features the following sections:
• Original Contributions
• Clinical Communications: Pediatric, Adult, OB/GYN
• Selected Topics: Toxicology, Prehospital Care, The Difficult Airway, Aeromedical Emergencies, Disaster Medicine, Cardiology Commentary, Emergency Radiology, Critical Care, Sports Medicine, Wound Care
• Techniques and Procedures
• Technical Tips
• Clinical Laboratory in Emergency Medicine
• Pharmacology in Emergency Medicine
• Case Presentations of the Harvard Emergency Medicine Residency
• Visual Diagnosis in Emergency Medicine
• Medical Classics
• Emergency Forum
• Editorial(s)
• Letters to the Editor
• Education
• Administration of Emergency Medicine
• International Emergency Medicine
• Computers in Emergency Medicine
• Violence: Recognition, Management, and Prevention
• Ethics
• Humanities and Medicine
• American Academy of Emergency Medicine
• AAEM Medical Student Forum
• Book and Other Media Reviews
• Calendar of Events
• Abstracts
• Trauma Reports
• Ultrasound in Emergency Medicine