{"title":"Fast image registration based upon projective planar geometry","authors":"J. Ostuni, S. Dunn","doi":"10.1109/NEBC.1993.404367","DOIUrl":"https://doi.org/10.1109/NEBC.1993.404367","url":null,"abstract":"The ability to perform an accurate comparison of images of a common object is an important tool for detecting localized changes on that object. The more accurate the comparison the better the ability to quantify these changes. A fast registration technique based upon a projective planar geometry is described. It allows the registration of two images to be performed by defining a pair of corresponding reference triangles in the images.<<ETX>>","PeriodicalId":159783,"journal":{"name":"1993 IEEE Annual Northeast Bioengineering Conference","volume":"20 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1993-03-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125117923","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
B. A. Suresh, G. Rao, A. Garcia, A. Scolpino, T. Denny
{"title":"Implementation of an expert system for detection of lymphocyte subsets using KEE","authors":"B. A. Suresh, G. Rao, A. Garcia, A. Scolpino, T. Denny","doi":"10.1109/NEBC.1993.404356","DOIUrl":"https://doi.org/10.1109/NEBC.1993.404356","url":null,"abstract":"Immunophenotyping is widely used in immunology research as well as clinical diagnosis. Combinations of cluster designation (CD) markers are used to determine the stage of leukemia progression and arrive at a diagnosis. Implementing this process using relational databases with or without temporal extensions is extremely cumbersome. However, using an expert system environment such as the knowledge engineering environment (KEE) for implementing the immunophenotyping process, simplifies data management issues. An expert system model for immunophenotyping has been developed. The system uses CD marker values obtained from flow cytometric analysis in order to characterize cell maturation stages and thereby diagnose the disease state using known facts. This work discusses the implementation of the knowledge base and the diagnosis process involved in it.<<ETX>>","PeriodicalId":159783,"journal":{"name":"1993 IEEE Annual Northeast Bioengineering Conference","volume":"41 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1993-03-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127440181","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Triaxial magnetometer, tesselated model of the thoracabdominal cavity during breathing","authors":"D. Silage, S. Levine","doi":"10.1109/NEBC.1993.404412","DOIUrl":"https://doi.org/10.1109/NEBC.1993.404412","url":null,"abstract":"A tesselated model to describe the configuration of the thoracabdominal cavity of the body during breathing is proposed. These measurements of surface areas and volumes are intended to describe the pattern of ventilation in health and disease. The orthogonal coordinates of sensors placed on the body are measured by a triaxial electromagnetic magnetometer. Results have shown that although an eight sensor tesselated model is relatively accurate for estimation, more sensors are required to accurately describe the thoracabdominal cavity. In addition, the current instrument has a low data rate and reduced frequency response. A multiprocessor digital receiver for the triaxial magnetometer system which will add more sensors and improve the performance is being designed.<<ETX>>","PeriodicalId":159783,"journal":{"name":"1993 IEEE Annual Northeast Bioengineering Conference","volume":"5 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1993-03-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133755218","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Correlation dimension in heart rate variability","authors":"Shenmin Zhang, S. Reisman, W. Tapp, P. Z. Zhang","doi":"10.1109/NEBC.1993.404437","DOIUrl":"https://doi.org/10.1109/NEBC.1993.404437","url":null,"abstract":"A study of the nonlinear dynamics and chaotic activity of heart rate variability by computing the correlation dimension of the interbeat interval (IBI) signal is discussed. Fourteen subjects (seven normal controls and seven chronic fatigue syndrome (CFS) patients) were analyzed and compared. The results of the study above indicate that normal subjects have a higher correlation dimension than CFS patients. This means that normal people need more past data than CFS patients to predict the future value. The study shows that the correlation dimension provides a useful way to measure the difference between sick and healthy people. It also points out that potential utility of dimension in a medical context.<<ETX>>","PeriodicalId":159783,"journal":{"name":"1993 IEEE Annual Northeast Bioengineering Conference","volume":"33 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1993-03-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134623155","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
J. Shea, M.P. Cruz, T. Delosso, S. Binder-Macleod, D. T. George, W. Santamore
{"title":"Comparison of cardiac and skeletal muscle contraction times: relevance to cardiomyoplasty","authors":"J. Shea, M.P. Cruz, T. Delosso, S. Binder-Macleod, D. T. George, W. Santamore","doi":"10.1109/NEBC.1993.404433","DOIUrl":"https://doi.org/10.1109/NEBC.1993.404433","url":null,"abstract":"A study comparing the timing of myocardial and skeletal muscle contraction is discussed. In 6 normal dogs latissimus dorsi muscle (LDM) contraction times were derived from LDM force and shortening measurements. The LDM was stimulated with a 5 pulse variable frequency pulse train (VFT) and a 6 pulse constant frequency pulse train (CFT). With 6 pulse CFT stimulation, the LDM time to peak shortening and total contraction times were 292.5 /spl plusmn/ 27.9 and 456.0 /spl plusmn/ 18.8 in the fresh muscle. With 5 pulse VFT stimulation, the LDM time to peak shortening and total contraction times were 242.5 /spl plusmn/ 17.6 and 395.5 /spl plusmn/ 8.7. Thus, in normal skeletal muscle (i.e., both slow type I fibers and fast type II fibers) contraction times may exceed left ventricular electromechanical contraction times (420 to 294 ms for heart rates from 60 to 120 beats/minute). This prolonged LDM contraction may impede diastolic filling of the left ventricle. Variable frequency stimulation decreases LDM contraction times and thus might prevent this filling impairment.<<ETX>>","PeriodicalId":159783,"journal":{"name":"1993 IEEE Annual Northeast Bioengineering Conference","volume":"64 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1993-03-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132092762","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Synaptic learning in VLSI-based artificial nerve cells","authors":"A. Laffely, S. Wolpert","doi":"10.1109/NEBC.1993.404399","DOIUrl":"https://doi.org/10.1109/NEBC.1993.404399","url":null,"abstract":"A VLSI method for analog synaptic learning in an electronic neuronal model is presented. This method reduces the size and complexity involved in implementing adaptive neuronally based controllers for robotic motion. It also provides for a continuous range of synaptic weights at both excitatory and inhibitory inputs while anticipating the need to interface to a pulse-driven system. The system is described, and test results indicate that it is able to alter the synaptic coupling on an inhibitory or an excitory input over a wide range.<<ETX>>","PeriodicalId":159783,"journal":{"name":"1993 IEEE Annual Northeast Bioengineering Conference","volume":"21 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1993-03-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128983867","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The structural adaptation of bone around a cortical defect","authors":"S. Shieh, M. Zimmerman, J. Parsons, N. Langrana","doi":"10.1109/NEBC.1993.404385","DOIUrl":"https://doi.org/10.1109/NEBC.1993.404385","url":null,"abstract":"Bone remodeling about a circular defect was evaluated by measuring the elastic properties of cortical bone with scanning acoustic microscopy. The defects were filled with either a void or rigid inclusion to create various states of stress in the vicinity of the defect. The remodeling observed after 6 months of implantation was of new bone formation on periosteal and endosteal surfaces about the defect region, effectively reducing the magnitude of stress concentration about the defect. There was no difference in the remodeling of bone about void and rigid inclusions. Both provoked significant degrees of surface remodeling that changed the basic structure of the bone cross-section at the level of the defect.<<ETX>>","PeriodicalId":159783,"journal":{"name":"1993 IEEE Annual Northeast Bioengineering Conference","volume":"98 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1993-03-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133971251","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Time frequency spectral representation of EEG","authors":"A. Nayak, R. Roy","doi":"10.1109/NEBC.1993.404439","DOIUrl":"https://doi.org/10.1109/NEBC.1993.404439","url":null,"abstract":"A study that uses a time frequency spectral representation (TFSR) with an exponential kernel to relate the changes in EEG spectrum to the depth of anesthesia is discussed. The level of anesthesia in the patient (dog) was changed by varying the halothane and tested using the tail clamp stimulus. The TFSR of the EEG did not change appreciably over the period of tail clamp when the patient was in deep sleep. For an awake patient the TFSR was localized in time and frequency. The energy was concentrated in the delta and the theta band frequencies and complete /spl alpha/ - blocking was observed. This shows that TFSR can be used as a possible aid to the anesthesiologist in detecting consciousness and hence prevent patient awareness.<<ETX>>","PeriodicalId":159783,"journal":{"name":"1993 IEEE Annual Northeast Bioengineering Conference","volume":"26 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1993-03-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127744529","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Context-dependent classification of medical images in the absence of complete class definitions","authors":"T. Jackson, M. Merickel","doi":"10.1109/NEBC.1993.404354","DOIUrl":"https://doi.org/10.1109/NEBC.1993.404354","url":null,"abstract":"A method is developed to automatically classify multispectral medical images using context-dependent methods. The model is built with the knowledge that clusters of tissue features will overlap in feature space. The goal is to correctly classify pixels in these overlapping regions. The model also allows for the possibility that there may be no match for a particular pixel. Initialization of the likelihood of a pixel belonging to a tissue class can take advantage of a priori class distributions if such knowledge exists. Otherwise, the model can resort to modeling each class with a Gaussian distribution. These likelihoods can then be iteratively updated using the relaxation labeling algorithm. Once the model converges, iterations cease and each pixel is classified using the maximum likelihood for all classes.<<ETX>>","PeriodicalId":159783,"journal":{"name":"1993 IEEE Annual Northeast Bioengineering Conference","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1993-03-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129374555","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Detection of skin displacement and capillary flow using an optical stethoscope","authors":"H. Hong, M. Fox","doi":"10.1109/NEBC.1993.404360","DOIUrl":"https://doi.org/10.1109/NEBC.1993.404360","url":null,"abstract":"The application of interferometry with the Doppler effect was utilized for the measurement of skin vibration due to vascular displacement (arterial pulse). Using optoelectronics and optical elements, the optical stethoscope can take the role of the conventional stethoscope but can also go beyond normal stethoscope functioning by detecting minute arterial pulsuations which would be subaudible, and by picking up capillary flow in the subepidermal layers. The preliminary results indicate it can provide useful information about the microcirculation and vascular pulse waves, noninvasively.<<ETX>>","PeriodicalId":159783,"journal":{"name":"1993 IEEE Annual Northeast Bioengineering Conference","volume":"24 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1993-03-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116671470","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}