D. Skyba, A. Jayaweera, F. Villanueva, S. Ismail, N. Goodman, S. Kaul
{"title":"A contrast echocardiography image analysis workstation used to quantify myocardial blood flow using left atrial injection of contrast","authors":"D. Skyba, A. Jayaweera, F. Villanueva, S. Ismail, N. Goodman, S. Kaul","doi":"10.1109/NEBC.1993.404365","DOIUrl":"https://doi.org/10.1109/NEBC.1993.404365","url":null,"abstract":"A contrast echocardiography workstation was developed and used to determine whether the myocardial transit rate of microbubbles injected into the left atrium would also correlate with regional myocardial blood flow (RMBF). End diastolic images were analyzed and time intensity plots are automatically derived from the anterior myocardium. It has been found that there is a close linear correlation between myocardial microbubble transit rate and RMBF in the 7 dogs tested (r=0.83, SEE=0.14, p<0.001). A poor correlation was noted between cardiac output and myocardial microbubble transit rate (r=0.43, p=0.14) suggesting that the myocardial transit rate of the microbubbles was not merely reflecting the input function. These findings and image analysis techniques may form the basis of measuring RMBF during myocardial contrast echocardiography following an intravenous injection of contrast.<<ETX>>","PeriodicalId":159783,"journal":{"name":"1993 IEEE Annual Northeast Bioengineering Conference","volume":"64 ","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1993-03-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"113989224","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Autoregressive analysis of dynamic vergence eye movement","authors":"J. Horng, J. Semmlow, G. Hung, K. Ciuffreda","doi":"10.1109/NEBC.1993.404411","DOIUrl":"https://doi.org/10.1109/NEBC.1993.404411","url":null,"abstract":"An autoregressive moving average model (ARMA) used to represent vergence eye movements in which the two eyes move in opposition to track targets varying in distance is discussed. The poles of the parametric models obtained from both left and right eye movements were used to analyze asymmetries associated with binocular and monocular control processes. Results suggest that a major portion of the neural control of vergence eye movements is independent and unique for each eye.<<ETX>>","PeriodicalId":159783,"journal":{"name":"1993 IEEE Annual Northeast Bioengineering Conference","volume":"34 5","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1993-03-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133237836","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Phase response curve analysis of heart rate variability with differing breathing rates","authors":"D. Cordero, W. Tapp, Pei Z. Zhang, S. Reisman","doi":"10.1109/NEBC.1993.404391","DOIUrl":"https://doi.org/10.1109/NEBC.1993.404391","url":null,"abstract":"The phase response curve (PRC) method, which quantitatively and visually analyzes heart rate variability (HRV), is presented. This method tracks moment-to-moment interactions between heart rate and respiration as two coupled systems and quantifies the strength of this coupling. It also allows for the quantitation of stimulus amplitude or depth of respiration. The phase plane plot gives a visual idea of the time dynamics, and at fast breathing rates, the differences are quite noticeable. The differences in the PRC seen in three packed breathing rates are presented. Thirteen subjects performed the breathing protocol at 8, 12 and 18 breaths per minute (BPM) in the seated position.<<ETX>>","PeriodicalId":159783,"journal":{"name":"1993 IEEE Annual Northeast Bioengineering Conference","volume":"52 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1993-03-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132345552","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Fractals in biology","authors":"L. Liebovitch","doi":"10.1109/NEBC.1993.404348","DOIUrl":"https://doi.org/10.1109/NEBC.1993.404348","url":null,"abstract":"In living systems, many objects in space or processes in time have fractal properties of self-similarity, scaling, and fractal dimension. The author describes these properties and their implications for analyzing data.<<ETX>>","PeriodicalId":159783,"journal":{"name":"1993 IEEE Annual Northeast Bioengineering Conference","volume":"7 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1993-03-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115192431","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Cheng Yi, E. Micheli-Tzanakou, D. Shindler, J. Kostis
{"title":"A new neural network algorithm to study myocardial reflected ultrasound for tissue characterization","authors":"Cheng Yi, E. Micheli-Tzanakou, D. Shindler, J. Kostis","doi":"10.1109/NEBC.1993.404397","DOIUrl":"https://doi.org/10.1109/NEBC.1993.404397","url":null,"abstract":"It is pointed out that ultrasonic myocardial tissue characterization is a promising approach to diagnose myocardial infarction since the acoustic properties of myocardial tissue are altered by the disease. Echocardiographic images are digitized to study ultrasound backscatter for tissue characterization. Neural network analysis is a successful approach to tissue characterization. A structure consisting of a multilayer perceptron combined with the feedback algorithm ALOPEX is proposed.<<ETX>>","PeriodicalId":159783,"journal":{"name":"1993 IEEE Annual Northeast Bioengineering Conference","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1993-03-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123396476","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Joint time and space regularization for the inverse problem of electrocardiography","authors":"G.M. Maratos, D.H. Brooks","doi":"10.1109/NEBC.1993.404370","DOIUrl":"https://doi.org/10.1109/NEBC.1993.404370","url":null,"abstract":"The authors attempt to characterize cardiac electrical activity based on non-invasive measurements on the torso surface and knowledge of body geometry. This problem is ill-conditioned and requires regularization. The authors present a new method for estimating the regularization parameter and a new method for using both temporal and spatial constraints in the regularization simultaneously.<<ETX>>","PeriodicalId":159783,"journal":{"name":"1993 IEEE Annual Northeast Bioengineering Conference","volume":"184 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1993-03-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124682048","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
M.P. Cruz, T. Delosso, J. Shea, D. T. George, W. Santamore
{"title":"A system to measure latissimus dorsi muscle function for cardiomyoplasty","authors":"M.P. Cruz, T. Delosso, J. Shea, D. T. George, W. Santamore","doi":"10.1109/NEBC.1993.404363","DOIUrl":"https://doi.org/10.1109/NEBC.1993.404363","url":null,"abstract":"Cardiomyoplasty is a new surgical treatment for heart failure in which the latissimus dorsi muscle (LDM) is wrapped around the heart and electrically stimulated to provide direct mechanical assist. The authors are interested in determining the effects of stimulation pattern and pharmacological interventions on LDM contractile performance with the hope of improving LDM performance for use in cardiomyoplasty. To directly evaluate LDM performance, without the confounding effects of the skeletal muscle wrap procedure, the authors developed an experimental system to measure the contractile function of the intact canine LDM during functional electrical stimulation. With this system the authors can measure the isometric and shortening performance of the canine LDM.<<ETX>>","PeriodicalId":159783,"journal":{"name":"1993 IEEE Annual Northeast Bioengineering Conference","volume":"6 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1993-03-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129399407","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A system for the automated processing of ion channel data","authors":"D. Curcie, W. Craelius","doi":"10.1109/NEBC.1993.404389","DOIUrl":"https://doi.org/10.1109/NEBC.1993.404389","url":null,"abstract":"Software which emulates an adaptive sixteen-level sampler is discussed. The software was applied to the thresholding analysis of ion channel data. Its utility for data compression is demonstrated for real-time applications.<<ETX>>","PeriodicalId":159783,"journal":{"name":"1993 IEEE Annual Northeast Bioengineering Conference","volume":"117 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1993-03-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121820442","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Implementation of a software model of the human glottis on a TMS32010 DSP to drive an artificial larnyx","authors":"D. Alzamora, D. Silage, R. Yantorno","doi":"10.1109/NEBC.1993.404351","DOIUrl":"https://doi.org/10.1109/NEBC.1993.404351","url":null,"abstract":"A glottal waveform generator has been constructed as part of a new approach for an artificial larynx prosthesis. In 1980, a palatal prosthesis device was developed at Thomas Jefferson Hospital to restore voice for laryngectomees. The present study, based on this approach, addresses this problem of generating the glottal pulses in real time to drive a small speaker that is placed on a dental plate inside the oral cavity. The glottal waveform will be generated and controlled with a hand-held electronic device and transmitted to a receiver on the dental plate. Ishizaka and Flanagan's 1972 two-mass model of the vocal cords has been used for the glottal pulse generation and was implemented on a TMS32010 DSP-chip-based PC-board.<<ETX>>","PeriodicalId":159783,"journal":{"name":"1993 IEEE Annual Northeast Bioengineering Conference","volume":"54 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1993-03-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116336327","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Multispectral ultrasound imaging and analysis of speckle generating medium","authors":"N. Rao, M. Aubry","doi":"10.1109/NEBC.1993.404421","DOIUrl":"https://doi.org/10.1109/NEBC.1993.404421","url":null,"abstract":"The use of FM pulse imaging scheme to obtain multispectral data from a speckle generating medium is discussed. Its potential for speckle reduction was evaluated by computing correlation coefficients. Measured coefficients were also compared with model predictions. The results are consistent with other published reports and show that significant speckle decorrelation can be achieved with this technique, if one averages frames acquired with center frequencies at the extreme ends of the transducer operating bandwidth, and a small enough /spl Delta/f. At these extremes, the transducer response is low. This response limitation can, however, be overcome by increasing the linear frequency sweep time duration in the FM pulse imaging scheme. In a frequency dependent attenuating medium, proper choices of f/sub o/ and /spl Delta/f spanning the entire operating bandwidth of transducer may be necessary. The flexibility inherent in the FM pulse scheme can be exploited here.<<ETX>>","PeriodicalId":159783,"journal":{"name":"1993 IEEE Annual Northeast Bioengineering Conference","volume":"58 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1993-03-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126568547","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}