Terese Torstensson, Gerd Almqvist-Tangen, Shawnee Waters, Jenny M Kindblom, Josefine Roswall, John E Chaplin, Lovisa Sjogren
{"title":"\"The big win was that we actually cooked\"- a qualitative interview study about the parental experience of Family Meals on Prescription for children living with obesity.","authors":"Terese Torstensson, Gerd Almqvist-Tangen, Shawnee Waters, Jenny M Kindblom, Josefine Roswall, John E Chaplin, Lovisa Sjogren","doi":"10.1186/s41043-025-00921-3","DOIUrl":"10.1186/s41043-025-00921-3","url":null,"abstract":"<p><strong>Purpose: </strong>The aim was to evaluate the parental experiences of participating in the randomized controlled trial \"Family Meals on Prescription\" for childhood obesity. The intervention consisted of a weekly prepacked grocery bag with recipes to cover five evening meals for the whole family.</p><p><strong>Methods: </strong>Parental, semi-structed interviews were performed with at least one parent of the participating families. Inclusion criteria was that the family had actively participated in the intervention. The interview questions were formulated to explore the experiences, opinions and attitudes of the parents regarding the intervention. The interviews were transcribed and thematically analysed using both an inductive and deductive approach.</p><p><strong>Results: </strong>Parents (six mothers and five fathers) from ten families were interviewed. The thematic analysis identified that the intervention reduced stress and was supportive regarding meal planning. The parents described an increased knowledge concerning food and cooking in the whole family and changes in meal behaviours such as more regular meals, trying new food and consuming more vegetables. Negative experience concerning the portion size being too large making it hard to maintain boundaries were also highlighted.</p><p><strong>Conclusion: </strong>Parents described that the intervention with a subsidized prepacked grocery bag supported them in adapting more positive behaviours related to family meals through decreased stress levels and including the children in the daily cooking in an encouraging way. This method has the potential to help this group by directly engaging the whole families in new behaviours and enhancing family cohesion.</p><p><strong>Registered: </strong>Registered at clinicaltrals.gov 27 Nov 2020, retrospectively registered: clinicaltrials.gov number 19,002,468. https://clinicaltrials.gov/study/NCT05225350 .</p><p><strong>What is known: </strong>Regular family meals and mealtime routines has been shown to be important for nutritional health and dietary patterns in children and adolescents. Intensive dietary intervention with a participatory approach in the home setting may be a novel tool in the treatment of childhood obesity.</p><p><strong>What is new: </strong>This study describes the parental experience of taking part of an intensive dietary intervention consisting of receiving prepacked grocery bags with the purpose to promote family meals. The parents described that the intervention led to more positive behaviours related to family meals.</p>","PeriodicalId":15969,"journal":{"name":"Journal of Health, Population, and Nutrition","volume":"44 1","pages":"171"},"PeriodicalIF":2.4,"publicationDate":"2025-05-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12102861/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144142722","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Global, regional and national burdens of alcoholic cardiomyopathy among the working-age population, 1990-2021: a systematic analysis.","authors":"Zhongkai Wang, Changyong Wu, Bingqing Zhang, Huang Sun, Wenjie Liu, Yuan Yang, Ying Gu, Lifei Pu, Lihui Zheng, Suli Bao, Yihua Luo, Ruijie Li, Yunzhu Peng","doi":"10.1186/s41043-025-00920-4","DOIUrl":"10.1186/s41043-025-00920-4","url":null,"abstract":"<p><strong>Objectives: </strong>Alcoholic cardiomyopathy (ACM) results from chronic alcohol misuse and primarily affects the working-age population (15-64 years). The global age-standardized rates (ASRs) of ACM disease burden declined slightly from 1990 to 2021, but the absolute cases increased, especially in high‒medium sociodemographic index (SDI) regions such as Eastern Europe. The aim of this study was to inform strategies to combat this preventable yet escalating health issue.</p><p><strong>Methods: </strong>We calculated estimated annual percentage changes (EAPCs) to quantify the dynamics of prevalence, deaths, and disability-adjusted life years (DALYs) for ACM. Decomposition analysis quantifies the contributor of disease burden in ACM. Additionally, we employed a health inequality analysis with two core indicators, the slope index (SI) and the concentration index (CIN), to assess national differences in the burden of ACM in relation to the SDI. Frontier analysis was used to identify preventable burdens with respect to optimized alcohol policies, particularly in high-middle SDI countries. Finally, we applied a Bayesian age‒cohort (BAPC) model to project the ACM burden to 2035.</p><p><strong>Results: </strong>This study revealed that the ASRs of prevalence, deaths, and DALYs decreased slightly from 1990 to 2021, whereas absolute cases of ACM continued to increase globally. Global income-based health disparities in ACM have intensified over the past 32 years, with high SDI populations disproportionately favoured. Population growth was the main driver of the increased ACM burden. The global burden of ACM is expected to increase in the future according to the BAPC model.</p><p><strong>Conclusions: </strong>The global burden of ACM continues to rise, primarily due to population ageing and insufficient prevention policies. This burden disproportionately impacts working-age populations, who face heightened vulnerability due to alcohol accessibility, premature mortality, and reduced workforce productivity. Moreover, economic growth paradoxically coincides with increased alcohol-related harm in regions with high-middle socioeconomic development-the alcohol control paradox. Projections highlight an urgent need for tailored alcohol control strategies, including stricter regulation and early cardiac screening in high-risk groups, to mitigate workforce productivity loss and align public health priorities with sustainable development goals.</p>","PeriodicalId":15969,"journal":{"name":"Journal of Health, Population, and Nutrition","volume":"44 1","pages":"170"},"PeriodicalIF":2.4,"publicationDate":"2025-05-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12103052/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144142731","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Majed Ramadan, Rbab Bajunaid, Jood Abdulhafeez Alansari, Hala Yusef, Rawiah A Alsiary
{"title":"The trends of mortality, aetiologies and risk factors of lower respiratory infections in Saudi Arabia from 1990 to 2021: results from the global burden of disease study 2021.","authors":"Majed Ramadan, Rbab Bajunaid, Jood Abdulhafeez Alansari, Hala Yusef, Rawiah A Alsiary","doi":"10.1186/s41043-025-00882-7","DOIUrl":"10.1186/s41043-025-00882-7","url":null,"abstract":"<p><strong>Background: </strong>Lower respiratory tract infections (LRIs) are the fourth leading cause of death globally, affecting all age groups and leading to over 2 million deaths annually. Saudi Arabia faces a significant burden from LRIs, affecting more than 15% of the population each year. This study aims to provide an overview of LRI mortality, etiologies, and risk factors in Saudi Arabia from 1990 to 2021.</p><p><strong>Method: </strong>Data on LRI mortality in Saudi Arabia from 1990 to 2021 were extracted from the 2021 edition of the Global Burden of Disease (GBD) Result Tool. The analysis encompassed mortality rates across all age groups, with particular emphasis on children under five and adults over 70. Four primary etiologies influenza, respiratory syncytial virus (RSV), Streptococcus pneumoniae, and Haemophilus influenzae type b (Hib) were examined, alongside 14 associated risk factors.</p><p><strong>Results: </strong>The total LRI deaths in Saudi Arabia decreased by 6% from 1990 to 2021, with a significant reduction observed among children under five years old (96%). In contrast, LRI mortality among adults over 70 increased by 16% during the same period. The age-standardized mortality rate decreased by 47%, with significant reductions in deaths associated with pneumococcus and RSV. However, risk factors, such as smoking and ambient particulate matter pollution, showed minimal declines or even increased mortality rates in older adults.</p><p><strong>Conclusion: </strong>Over the past three decades, Saudi Arabia has made significant progress in reducing LRI mortality, particularly among children under five. However, the increasing mortality rates among the elderly highlight the need for targeted interventions to address their unique vulnerabilities. Continued investment in public health infrastructure, vaccination coverage, and environmental health initiatives is essential for further reducing the burden of LRIs in Saudi Arabia.</p>","PeriodicalId":15969,"journal":{"name":"Journal of Health, Population, and Nutrition","volume":"44 1","pages":"172"},"PeriodicalIF":2.4,"publicationDate":"2025-05-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12102968/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144142692","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Nutritional experiences of Turkish university students with type 1 diabetes: a qualitative study.","authors":"Şebnem Özgen Özkaya, Volkan Özkaya, Erman Gedıklı, Muazzez Garıpağaoğlu","doi":"10.1186/s41043-025-00908-0","DOIUrl":"10.1186/s41043-025-00908-0","url":null,"abstract":"<p><strong>Background: </strong>This study was performed in order to describe the nutritional experiences of university students with Type 1 diabetes who try to carry on their educational and social lives together in diabetes self-management.</p><p><strong>Methods: </strong>In this descriptive and qualitative study, face-to-face and semi-structured in-depth interviews were performed with 15 university students with Type 1 diabetes, aged 18-30, resided in Istanbul, who were diagnosed with Type 1 diabetes at least 5 years ago. The data collection process was performed by the researchers. The interviews were recorded and transcribed. The data collected in accordance with the phenomenological approach were processed using guided content analysis.</p><p><strong>Results: </strong>In the interview with the participants, whose mean age was 21.86 ± 2.03 years and 66.7% of those were female, 6 themes were listed as positive and negative experiences of students in diabetes management in the university environment, general nutritional preferences, nutritional attitudes in non-routine and social environments, regular nutrition and quality of campus life, nutrition during the exercise/sports period, university support and students' expectations from the environment and explained by their sub-dimensions.</p><p><strong>Conclusion: </strong>The change in living conditions with the transition to campus life, the new social environment, individualization and academic responsibilities make diabetes self-management a challenging, complex and supportive process. This study might guide the enhancement of university students' living conditions with diabetes.</p>","PeriodicalId":15969,"journal":{"name":"Journal of Health, Population, and Nutrition","volume":"44 1","pages":"169"},"PeriodicalIF":2.4,"publicationDate":"2025-05-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12102960/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144142688","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Amr Ali Mohamed Abdelgawwad El-Sehrawy, Maryam Jafari, Ahmed Hussein Zwamel, Pegah Rashidian, Suhas Ballal, Rishiv Kalia, Anima Nanda, Laxmidhar Maharana, Sepide Javankiani, Mohammad Hashemi, Ehsan Amini-Salehi
{"title":"Neutrophil Percentage-to-Albumin Ratio and Neutrophil-to-Albumin Ratio as novel biomarkers for non-alcoholic fatty liver disease: a systematic review and meta-analysis.","authors":"Amr Ali Mohamed Abdelgawwad El-Sehrawy, Maryam Jafari, Ahmed Hussein Zwamel, Pegah Rashidian, Suhas Ballal, Rishiv Kalia, Anima Nanda, Laxmidhar Maharana, Sepide Javankiani, Mohammad Hashemi, Ehsan Amini-Salehi","doi":"10.1186/s41043-025-00926-y","DOIUrl":"10.1186/s41043-025-00926-y","url":null,"abstract":"<p><strong>Background: </strong>Non-alcoholic fatty liver disease (NAFLD) is a major global health concern, with rising prevalence linked to obesity, insulin resistance, and metabolic syndrome. Timely and accurate identification of individuals at risk is crucial for improving outcomes. Recently, systemic inflammatory and nutritional markers such as the Neutrophil Percentage-to-Albumin Ratio (NPAR) and the Neutrophil-to-Albumin Ratio (NAR) have emerged as promising non-invasive biomarkers for NAFLD. Both ratios reflect inflammation and hepatic nutritional status, offering potential utility in predicting disease presence and progression. This systematic review and meta-analysis aimed to evaluate the diagnostic value of NPAR and NAR in patients with NAFLD.</p><p><strong>Methods: </strong>A comprehensive search was performed across databases including PubMed, Embase, Scopus, and Web of Science from inception to December 28, 2024. Data extraction was carried out using a standardized form, and the methodological quality of included studies was assessed using the Newcastle-Ottawa Scale. Statistical analyses were performed using STATA version 18, employing a random-effects model.</p><p><strong>Results: </strong>The meta-analysis demonstrated that both the Neutrophil Percentage-to-Albumin Ratio (NPAR) and the Neutrophil-to-Albumin Ratio (NAR) were significantly higher in patients with NAFLD compared to healthy individuals. NPAR showed a standardized mean difference (SMD) of 0.28 (95% CI: 0.22-0.35, P < 0.01), while NAR had a higher effect size with an SMD of 0.69 (95% CI: 0.44-0.93, P < 0.01). The pooled diagnostic performance of NPAR yielded a sensitivity of 69.5% (95% CI: 56.3-82.6%), specificity of 63.1% (95% CI: 46.6-70.0%), and an area under the curve (AUC) of 76.05% (95% CI: 66.3-85.7%). For NAR, the pooled sensitivity was 65.0% (95% CI: 49.0-82.0%), specificity was 63.0% (95% CI: 47.0-79.0%), and AUC was 69.0% (95% CI: 48.0-89.0%).</p><p><strong>Conclusion: </strong>In conclusion, both NPAR and NAR were found to be elevated in individuals with NAFLD, supporting their potential as non-invasive and accessible biomarkers. These ratios reflect key aspects of systemic inflammation and nutritional status, offering clinical value in early detection and risk stratification. However, given the limited number of studies available-particularly for NAR-further research is needed to confirm these findings, establish standardized thresholds, and assess their performance across diverse populations and clinical settings.</p><p><strong>Clinical trial number: </strong>Not applicable.</p>","PeriodicalId":15969,"journal":{"name":"Journal of Health, Population, and Nutrition","volume":"44 1","pages":"167"},"PeriodicalIF":2.4,"publicationDate":"2025-05-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12102820/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144142686","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A multilevel analysis of factors associated with stunting among children under five years in Lesotho: a study of the lesotho multiple cluster indicator survey 2018.","authors":"Nthatisi Leseba, Kerry Vermaak, Tiisetso Makatjane, Mapitso Lebuso","doi":"10.1186/s41043-025-00901-7","DOIUrl":"10.1186/s41043-025-00901-7","url":null,"abstract":"<p><strong>Background: </strong>The United Nations Children's Fund (UNICEF) states that inadequate nutrition during the first 1,000 days of a child's life can contribute to stunted growth. Lesotho is currently experiencing a high prevalence of malnutrition across all age groups. Therefore, this study aims to investigate the prevalence and multilevel factors associated with stunting among children under five in Lesotho.</p><p><strong>Methods: </strong>The study used the Lesotho Multiple Cluster Indicator Survey of 2018. The data was analysed using STATA version 14 software, and a multilevel logistic regression model was fitted. The Wald adjusted odds ratio (WAOR) with a P-value < 0.05 was also taken to indicate statistical significance.</p><p><strong>Results: </strong>The prevalence of stunting was 33.6% [95% CI 31.6 33.6] amongst the children under five years old in Lesotho. At an individual level, the odds of stunting are lower for the children that did not receive the minimum acceptable diet (MAD) (WAOR = 0.52; CI: 0.3, 0.9), the children born with greater than 3.8 kg birth weight (WAOR = 0.51; CI: 0.4, 0.6), and those that did not have respiratory infections (WAOR = 0.61; CI: 0.4, 1.0) compared to their counterparts. At the household level, the likelihood of stunting was the lowest for education beyond secondary (WAOR = 0.26; CI: 0.2, 0.4), the fifth household wealth (WAOR = 0.34; CI: 02, 03), the safe sources of drinking water (WAOR = 0.72; CI: 06, 09) and inadequate toilet facilities (WAOR = 0.62; CI: 0.5, 0.7) compared to their counterparts. Higher odds were observed amongst the children from rural areas (WAOR = 1.95; CI: 1.3, 2.1), and mothers not residing within the household (WAOR = 1.30; CI: 1.1, 1.6) compared to their counterparts. At the community level, decreased odds were associated with the children from the communities with high community maternal education (WAOR = 0.69; CI: 0.6, 0.8) and the community male education (WAOR = 0.56; CI: 0.5, 0.7), as well as those in the communities with low safety of drinking water sources (WAOR = 0.73; CI: 0.3, 0.5), adequate toilet facilities (WAOR = 0.66; CI: 0.5, 0.8) and high maternal media exposure (WAOR = 0.37; CI: 0.3, 0.5) compared counterparts. The children from communities with high community poverty were two times (WAOR = 2.04; CI: 1.7, 2.5) more likely to be stunted.</p><p><strong>Conclusion: </strong>The findings suggest targeting community food availability and knowledge acquisition. Expanding information availability through mass media would improve the nutritional status of children in Lesotho.</p>","PeriodicalId":15969,"journal":{"name":"Journal of Health, Population, and Nutrition","volume":"44 1","pages":"168"},"PeriodicalIF":2.4,"publicationDate":"2025-05-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12103028/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144142725","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Preconception health risks among women of reproductive age in Sub-Saharan Africa: a systematic review of implications for preconception care.","authors":"Gebremedhin Gebreegziabher Gebretsadik, Andargachew Kassa Biratu, Amanuel Gessessew, Zohra S Lassi, Alemayehu Bayray Kahsay, Afework Mulugeta","doi":"10.1186/s41043-025-00888-1","DOIUrl":"10.1186/s41043-025-00888-1","url":null,"abstract":"<p><strong>Introduction: </strong>Although preconception health risks are strongly linked to adverse pregnancy outcomes and offer opportunities to improve women's health, consolidated evidence remains limited in Sub-Saharan Africa (SSA). This review aims to synthesize evidence on preconception health risks in SSA, a region with the highest global rates of maternal and neonatal mortality and morbidity.</p><p><strong>Methods: </strong>We searched PubMed/MEDLINE, African Index Medicus, ScienceDirect, and Google Scholar for studies published up to June 30, 2023. Two reviewers independently assessed study quality using Joanna Briggs Institute tools. Studies with at least one modifiable preconception risk were included. Due to inconsistencies in outcome measurements, participant variability, and high heterogeneity, a meta-analysis was not reported. Findings were summarized in text, figures, and tables.</p><p><strong>Results: </strong>In the review, researchers selected 83 articles from a total of 3,425 retrieved articles. Overall, this review revealed a high proportion of preconception health risks among the participants which includes underweight (0.64% to 36.2%), overweight (8.3% to 76.7%), anemia (36.7% to 58.1%), unintended pregnancy (4.2% to 94.3%), alcohol intake (5.3% to 68.7%), smoking (1.1% to 20.3%), chewing khat (9.9% to 27.6%), history of chronic medical conditions (2% to 16.6%), a history of adverse pregnancy outcomes (11% to 51.9%), sexually transmitted infections (1.3% to 29.2%), psychosocial distress (13.9% to 60%), and intimate partner violence (6.7% to 43.7%).</p><p><strong>Conclusion: </strong>The systematic review found that numerous women in SSA encounter various preconception health risks factors. Therefore, the governments of respective countries need to give emphasis and adopt policies to integrate preconception care services in to the existing healthcare system so that both financial and human resources need to be mobilized. There is gaps in research, as the true burden of preconception health risks may be underestimated due to fragmented risk assessment methods.</p><p><strong>Review registration: </strong>(PROSPERO: CRD42023446801).</p>","PeriodicalId":15969,"journal":{"name":"Journal of Health, Population, and Nutrition","volume":"44 1","pages":"164"},"PeriodicalIF":2.4,"publicationDate":"2025-05-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12096783/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144119872","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Haoran Wang, Runhua Tang, Shuhang Luo, Huimin Hou, Jianyong Liu, Ming Liu, Jianye Wang
{"title":"Association of life's crucial 9 score with benign prostatic hyperplasia: a cross-sectional study.","authors":"Haoran Wang, Runhua Tang, Shuhang Luo, Huimin Hou, Jianyong Liu, Ming Liu, Jianye Wang","doi":"10.1186/s41043-025-00925-z","DOIUrl":"10.1186/s41043-025-00925-z","url":null,"abstract":"<p><strong>Background: </strong>Benign prostatic hyperplasia (BPH) and prostate cancer (PCa) are prevalent prostate diseases in aging male populations, with significant implications for quality of life and healthcare burden. While cardiovascular health (CVH) and lifestyle factors have been linked to aging and chronic diseases, their association with prostate diseases remains underexplored.</p><p><strong>Objective: </strong>This study investigates the relationship between CVH, assessed using the Life's Crucial 9 (LC9) score, and the risk of prostate diseases, including BPH and PCa, in a large UK cohort.</p><p><strong>Methods: </strong>Data from 26,656 male participants in the UK Biobank were analyzed. The LC9 score, an expanded CVH metric incorporating mental health, was calculated based on physical, metabolic, and psychological factors. Logistic regression and restricted cubic spline analyses were performed to examine associations between the LC9 score and prostate diseases. Subgroup and interaction analyses were conducted to explore potential modifiers.</p><p><strong>Results: </strong>A higher LC9 score was significantly associated with a lower risk of BPH in both continuous and categorical models (P < 0.001). The association demonstrated a linear dose-response relationship, with the inflection point at an LC9 score of 72.5. Subgroup analysis revealed stronger protective effects in participants with lower socioeconomic deprivation. However, no significant association was observed between the LC9 score and PCa risk, even in subgroup analyses.</p><p><strong>Conclusions: </strong>This study highlights the importance of overall cardiovascular and psychological health in reducing BPH risk, emphasizing the need for sustained healthy behaviors. The absence of a significant link between the LC9 score and PCa suggests distinct pathophysiological mechanisms and warrants further research. These findings provide valuable insights for targeted prevention and management strategies in prostate health.</p>","PeriodicalId":15969,"journal":{"name":"Journal of Health, Population, and Nutrition","volume":"44 1","pages":"163"},"PeriodicalIF":2.4,"publicationDate":"2025-05-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12090484/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144101848","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The association between HPV vaccination and new-onset cardiovascular and cerebrovascular diseases: based on a retrospective study.","authors":"Chiao-Yu Yang, Yu-Hsiang Shih, Chia-Chi Lung","doi":"10.1186/s41043-025-00918-y","DOIUrl":"10.1186/s41043-025-00918-y","url":null,"abstract":"<p><strong>Introduction: </strong>Human papillomavirus (HPV), a widespread sexually transmitted infection, is well-known for its association with cancers like cervical, anal, and oropharyngeal. While extensively studied for its oncogenic properties, HPV's influence on these non-cancerous conditions remains under investigation. This study examines the impact of HPV vaccination on the incidence of cardiovascular and cerebrovascular diseases, exploring its protective potential.</p><p><strong>Methods: </strong>Utilizing the global TriNetX database, this retrospective cohort study analyzed data from adults aged 20 to 40 who were either vaccinated or not vaccinated against HPV between January 1, 2019, and December 31, 2021. The study employed propensity score matching to ensure balanced comparison groups and utilized ICD-10 codes to identify new-onset cardiovascular and cerebrovascular diseases.</p><p><strong>Results: </strong>The study included 59,423 vaccinated and an equal number of unvaccinated individuals, balanced for various demographic and health characteristics. The vaccinated group demonstrated a lower incidence of cardiovascular diseases (hazard ratio [HR] = 0.9, 95% CI 0.847-0.957), cerebrovascular diseases (HR = 0.605, 95% CI 0.484-0.754), and heart dysfunction (HR = 0.833, 95% CI 0.708-0.98) compared to the unvaccinated group. Subgroup analyses further supported the protective effect of HPV vaccination across different demographics.</p><p><strong>Conclusion: </strong>HPV vaccination is linked to a lower risk of new-onset cardiovascular and cerebrovascular diseases in adults, suggesting broader health benefits beyond cancer prevention. These results advocate for incorporating cardiovascular health into public health strategies promoting HPV vaccination. Further research is necessary to understand the mechanisms and validate these protective effects across diverse populations and extended follow-up periods.</p>","PeriodicalId":15969,"journal":{"name":"Journal of Health, Population, and Nutrition","volume":"44 1","pages":"162"},"PeriodicalIF":2.4,"publicationDate":"2025-05-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12090540/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144101798","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Serum zinc concentration and history of isCGM contact dermatitis in type 1 diabetes.","authors":"Mitsunobu Kubota, Shizuka Matsuda, Mimu Matsuda, Shinji Maeda, Sayo Yoshiyama","doi":"10.1186/s41043-025-00927-x","DOIUrl":"10.1186/s41043-025-00927-x","url":null,"abstract":"<p><strong>Background: </strong>In insulin treatment for type 1 diabetes, intermittent scanning continuous glucose monitoring (isCGM: FreeStyle® Libre), in which a sensor is adhered to the skin, is often used to monitor blood glucose fluctuations and manage glucose levels. Zinc-deficient skin is reportedly more susceptible to primary irritant rashes. This study investigated whether zinc deficiency is associated with a history of contact dermatitis caused by isCGM in patients with type 1 diabetes.</p><p><strong>Methods: </strong>The subjects comprised 55 patients (23 men, 32 women, age 57.9 ± 17.6 years) with type 1 diabetes who were outpatients at our department and had a history of isCGM use. We examined the history of contact dermatitis due to isCGM in relation to serum zinc concentration.</p><p><strong>Results: </strong>Serum zinc was significantly lower in those with history of contact dermatitis (23 subjects) compared to those without (32 subjects) (P = 0.033). History of contact dermatitis due to isCGM was negatively associated with both age (β = - 0.266, P = 0.040) and zinc deficiency category (β = - 0.315, P = 0.017).</p><p><strong>Conclusions: </strong>For people undergoing treatment for type 1 diabetes for whom skin problems caused by isCGM are a barrier to glucose management, screening of serum zinc concentration may be important.</p>","PeriodicalId":15969,"journal":{"name":"Journal of Health, Population, and Nutrition","volume":"44 1","pages":"161"},"PeriodicalIF":2.4,"publicationDate":"2025-05-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12084942/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144094001","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}