{"title":"Research productivity, collaboration patterns, and socio-economic correlates of rheumatic fever and rheumatic heart disease research in Southeast Asia: a bibliometric analysis.","authors":"Maria Llaine J Callanta, Patrick R Relacion","doi":"10.1186/s41043-026-01354-2","DOIUrl":"10.1186/s41043-026-01354-2","url":null,"abstract":"<p><strong>Background: </strong>Rheumatic fever and rheumatic heart disease (RF/RHD) remain important causes of preventable cardiovascular morbidity in low- and middle-income settings, including Southeast Asia. Although research output on these conditions has increased globally, the extent, thematic focus, and distribution of research productivity within Southeast Asia have not been comprehensively characterized. This study aimed to examine the publication trends, collaboration patterns, funding distribution, thematic focus, and selected socio-economic correlates of rheumatic fever and rheumatic heart disease research in Southeast Asia using bibliometric methods.</p><p><strong>Methods: </strong>Original articles and conference papers on RF/RHD in SEA from 1900 to 2024 were identified using the Scopus database. Bibliometric indicators and citation data were extracted and summarized descriptively. Country collaboration networks and author keyword co-occurrence maps were visualized using VOSviewer. Associations between selected country-level socio-economic indicators and bibliometric measures were explored using correlation analysis.</p><p><strong>Results: </strong>A total of 333 records on RF/RHD published between 1900 and 2024 from various SEA countries were obtained. Regional publication output remained relatively high in recent years, although annual counts fluctuated and the 2024 output was incomplete at the time of search. Thailand, Indonesia, Malaysia, Singapore, and the Philippines accounted for the largest share of regional output. However, despite this positive trend, SEA's contribution to the global output for RF/RHD research is still below 2.5%. Notably, only one-fifth of the regional publications reported funding support, with marked disparities across countries. The retrieved literature was concentrated in themes related to diagnosis, surgery and complications, registries and epidemiology, anticoagulation, and valvular assessment. In contrast, topics such as social determinants of health, cost-effectiveness, implementation research, and patient-centered care appeared less represented. Country-level research productivity showed positive associations with selected socio-economic indicators and international collaboration, although these findings should be interpreted cautiously.</p><p><strong>Conclusion: </strong>Research on RF/RHD in Southeast Asia has grown, but publication output and funding remain unevenly distributed across countries. Continued efforts to strengthen international collaboration and research support are needed to amplify research productivity in low-resource Southeast Asian settings.</p>","PeriodicalId":15969,"journal":{"name":"Journal of Health, Population, and Nutrition","volume":" ","pages":""},"PeriodicalIF":3.7,"publicationDate":"2026-06-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13505024/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148211435","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ling Ren, Dawei Liu, Bo Zhou, Jie Liu, Changqing Yu
{"title":"The association between triglyceride-glucose index and major adverse cardiovascular and cerebrovascular events in patients with heart failure.","authors":"Ling Ren, Dawei Liu, Bo Zhou, Jie Liu, Changqing Yu","doi":"10.1186/s41043-026-01369-9","DOIUrl":"10.1186/s41043-026-01369-9","url":null,"abstract":"<p><strong>Objective: </strong>This study aimed to verify the association between triglyceride-glucose (TyG) and major adverse cardiovascular and cerebrovascular events (MACCE) in patients with heart failure (HF).</p><p><strong>Methods: </strong>This single-center retrospective cohort study enrolled 927 patients with HF. Participants were categorized into four groups based on TyG index quartiles: Q1 (n = 227), Q2 (n = 237), Q3 (n = 234), and Q4 (n = 229). According to the occurrence of MACCE, they were further classified into non-MACCE (n = 847) and MACCE (n = 80) groups. Cox regression, subgroup analysis, receiver operating characteristic (ROC) curve analysis, Kaplan-Meier survival curves, and restricted cubic spline (RCS) plots were employed to evaluate the association between the TyG index and MACCE risk.</p><p><strong>Results: </strong>Multivariable Cox regression analysis demonstrated that the TyG index remained independently associated with the risk of MACCE after adjusting for lifestyle factors, comorbidities, treatments, and key laboratory and echocardiographic parameters. Each 1-unit increase in TyG was associated with an 85.4% increase in MACCE risk (HR: 1.336-2.572, P < 0.001). Patients in the highest TyG quartile (Q4) had a 3.679-fold higher risk of MACCE compared to those in the lowest quartile (Q1) (HR: 1.702-7.956, P = 0.001). Subgroup analyses revealed that the association was more pronounced in females, patients aged > 75 years, those with chronic HF, hypertension, and those without chronic kidney disease (P for interaction = 0.021 and 0.035 for gender and hypertension, respectively). Sensitivity analyses addressing endpoint heterogeneity showed a stronger association between TyG and \"hard endpoints\" (HR per unit: 2.01, P < 0.001), with significant net reclassification improvement at 12 months. ROC analysis indicated a modest predictive value of TyG for MACCE (AUC = 0.587, 95% CI: 0.525-0.649, P = 0.010). Kaplan-Meier curves showed significant differences in cumulative event risk across TyG groups (Log-rank P = 0.025). RCS analysis indicated a significant positive linear dose-response relationship between TyG and MACCE risk (P for nonlinearity > 0.05).</p><p><strong>Conclusion: </strong>The TyG index exhibits a significant positive linear association with the risk of MACCE in patients with HF. As a simple and readily accessible metabolic marker, the TyG index may provide supplementary prognostic information when considered alongside established clinical risk factors in this population.</p>","PeriodicalId":15969,"journal":{"name":"Journal of Health, Population, and Nutrition","volume":" ","pages":""},"PeriodicalIF":3.7,"publicationDate":"2026-06-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13504782/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148217811","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Development and validation of a short-form Tuberculosis Medication Adherence Scale (TBMAS-SF).","authors":"Wei Zang, Xiaoxin Zhang, Wenjing Gu, Lutong Pan, Ziying Yu, Yunchou Wu, Ting Li","doi":"10.1186/s41043-026-01349-z","DOIUrl":"https://doi.org/10.1186/s41043-026-01349-z","url":null,"abstract":"<p><strong>Background: </strong>In this study, weemployed classical test theory (CTT) to develop and validate a concise, abbreviated version of the Tuberculosis Medication Adherence Scale (TBMAS-SF). This shortened version aims to provide a more efficient measurement tool for tuberculosis patients while maintaining acceptable psychometric properties.</p><p><strong>Methods: </strong>A survey of tuberculosis patients undergoing treatment at the Heilongjiang Provincial Institute of Infectious Disease Control and Prevention was conducted using convenient sampling and the TBMAS. Data analysis was performed using SPSS 26.0 and Amos 24.0. A total of 496 questionnaires were distributed in this study, with 404 valid responses collected, resulting in a valid response rate of 81.45%.</p><p><strong>Results: </strong>The analysis revealed that the TBMAS-SF demonstrated acceptable reliability, with a Cronbach's α coefficient of 0.931 and a split-half reliability of 0.739. Confirmatory factor analysis indicated that the TBMAS-SF demonstrated acceptable comparative fit but suboptimal absolute fit, with a chi-square degrees of freedom ratio of 4.981, RMSEA = 0.141, RMR = 0.014 (which is less than 0.05), CFI and IFI values exceeding 0.9, and NFI and TLI values approaching 0.9. There was a statistically significant but modest positive correlation between the TBMAS-SF score and medication literacy score (r = 0.228, p < 0.01), suggesting limited but acceptable empirical validity.</p><p><strong>Conclusion: </strong>The TBMAS-SF demonstrates acceptable internal consistency and promising construct validity, though suboptimal absolute fit indices warrant further refinement and cross-validation.</p>","PeriodicalId":15969,"journal":{"name":"Journal of Health, Population, and Nutrition","volume":" ","pages":""},"PeriodicalIF":2.8,"publicationDate":"2026-06-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148199266","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ke Wang, Jinzhen Gong, Ziting Yuan, Ruiyan Wang, Mengyu He, Yuli Huang, Jing Zhou, Feng Wang
{"title":"Association of the Naples prognostic score with all-cause and cardiovascular mortality in U.S. patients with heart failure: a retrospective cohort study using NHANES 2001-2018.","authors":"Ke Wang, Jinzhen Gong, Ziting Yuan, Ruiyan Wang, Mengyu He, Yuli Huang, Jing Zhou, Feng Wang","doi":"10.1186/s41043-026-01352-4","DOIUrl":"10.1186/s41043-026-01352-4","url":null,"abstract":"<p><strong>Background: </strong>Naples Prognostic Score (NPS) predicts mortality risk in heart failure (HF).</p><p><strong>Methods and results: </strong>This retrospective cohort study utilized data from the 2001-2018 National Health and Nutrition Examination Survey (NHANES), including 1,111 adults with HF. The NPS was calculated based on serum albumin (SA), total cholesterol (TC), neutrophil-to-lymphocyte ratio (NLR), and lymphocyte-to-monocyte ratio (LMR). Mortality outcomes were ascertained through linkage with the National Death Index (NDI). Associations between NPS and all-cause mortality (ACM) and cardiovascular mortality (CVM) were evaluated using survey-weighted Cox proportional hazards models and Kaplan-Meier (KM) analyses. Subgroup and sensitivity analyses were performed to assess the robustness of the findings. Over a median follow-up of 70 months (interquartile range [IQR], 36-114 months), 545 ACM and 202 CVM cases were documented. Compared with participants with an NPS of 0, those in the high-risk group (NPS: 3-4) had significantly increased risks of mortality, with adjusted hazard ratios (HRs) of 2.53 (95% confidence interval [CI], 1.38-4.63; P < 0.01) for ACM and 2.62 (95% CI, 1.20-5.74; P < 0.05) for CVM. These associations remained consistent across subgroup and sensitivity analyses, supporting the robustness of the results.</p><p><strong>Conclusion: </strong>A higher NPS was independently associated with increased risks of ACM and CVM among U.S. adults with HF. These findings suggest that NPS may serve as a useful prognostic marker; however, further validation in prospective clinical cohorts is warranted.</p>","PeriodicalId":15969,"journal":{"name":"Journal of Health, Population, and Nutrition","volume":" ","pages":""},"PeriodicalIF":3.7,"publicationDate":"2026-06-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13563757/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148176158","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Richard Moore, Abdel-Karim Al-Tamimi, Lambros Lazuras
{"title":"PhysB: a framework for designing conversational agents to support physical activity in adolescents.","authors":"Richard Moore, Abdel-Karim Al-Tamimi, Lambros Lazuras","doi":"10.1186/s41043-026-01254-5","DOIUrl":"10.1186/s41043-026-01254-5","url":null,"abstract":"<p><p>Conversational Agents (CAs) are a promising tool for enhancing adolescents' physical activity behaviours. To effectively fulfil their role, these agents must address the diverse range of barriers adolescents encounter and provide effective, evidence-based solutions. To achieve this, a theoretical framework titled PhysB is proposed, which is grounded in theory and evidence, allowing for the identification and categorisation of barriers through natural language input. The PhysB framework outlines the relationship between the process of identifying barriers and the cognitive system driving the CA's interaction with adolescents. It incorporates key constructs from various theoretical models and frameworks and draws from behaviour change theory. The PhysB framework's main function is to inform the design and evaluation of personalised, evidence-based conversational AI interventions to promote positive behaviour change in adolescents. The PhysB framework's broad applicability extends to practitioners, policymakers, researchers, and designers involved in designing conversational AI interventions.</p>","PeriodicalId":15969,"journal":{"name":"Journal of Health, Population, and Nutrition","volume":" ","pages":""},"PeriodicalIF":3.7,"publicationDate":"2026-06-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13660111/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148194767","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Mobina Imannezhad, Susan Darroudi, Maryam Saberi-Karimian, Habibollah Esmaily, Mohsen Moohebati, Simin Rashidian, Sara Ghazizadeh, Gordon A Ferns, Majid Ghayour-Mobarhan, Maryam Alinezhad-Namaghi
{"title":"Association of emerging anthropometric ratios with arterial stiffness risk measured by pulse wave velocity: insights from a middle-eastern population.","authors":"Mobina Imannezhad, Susan Darroudi, Maryam Saberi-Karimian, Habibollah Esmaily, Mohsen Moohebati, Simin Rashidian, Sara Ghazizadeh, Gordon A Ferns, Majid Ghayour-Mobarhan, Maryam Alinezhad-Namaghi","doi":"10.1186/s41043-026-01338-2","DOIUrl":"10.1186/s41043-026-01338-2","url":null,"abstract":"<p><strong>Background: </strong>Arterial stiffness (AS), a strong risk factor for atherosclerosis and coronary artery disease (CAD), is typically assessed using pulse wave velocity (PWV). This study takes a unique approach by exploring the relationship between novel anthropometric indices and AS in a large cohort study.</p><p><strong>Method: </strong>This cross-sectional study was conducted during Phase II of the Mashhad Stroke and Heart Atherosclerotic Disorders (MASHAD) study, a 10-year cohort (2010-2020). Out of the original 9704 participants at the beginning of the MASHAD cohort study, 310 healthy participants, 206 individuals without confirmed cardiovascular disease (CVD), and 307 individuals with confirmed major cardiovascular events were randomly selected. PWV test was conducted using a specialized SphygmoCor XCEL System, and participants were grouped into two CVD and two non-CVD groups based on the median PWV < 6.9 or ≥ 6.9.</p><p><strong>Result: </strong>A total of 823 individuals took part in the study. The CVD group with PWV ≥ 6.9 m/s had the highest mean age of 51.37 ± 7.07 years. Multinomial logistic regression analysis revealed that with each unit increase in weight-adjusted waist index (WWI) and visceral adiposity index (VAI), the odds of AS increased by 25.7% [OR: 1.257 (1.002-1.576)] and 13.9% [OR: 1.139 (1.022-1.271)] (P-value = 0.048 and 0.019, respectively). Additionally, as lipid accumulation product (LAP) increased, the AS decreased by 0.4% [OR: 0.996 (0.993-0.999)] (P-value = 0.01). Moreover, height and arm-to-height ratio (AHR) resulted in a 3.7% [OR: 1.037 (1.003-1.073)] and 6.4% [OR: 1.064 (1.002-1.131)] increase in PWV risk (P-value = 0.034 and 0.044). In the CVD-, PWV ≥ 6.9 group, VAI posed a 16.4% [OR: 1.164 (1.051-1.289)] (P-value = 0.004) increase in AS with a one-unit increment.</p><p><strong>Conclusion: </strong>WWI and VAI showed significant associations with AS in CVD patients. VAI was also linked to AS in non-CVD patients, with a stronger association than height and AHR. This contributes significantly to our understanding of vascular health. Equally noteworthy is the protective association of LAP against AS in non-CVD individuals.</p>","PeriodicalId":15969,"journal":{"name":"Journal of Health, Population, and Nutrition","volume":" ","pages":""},"PeriodicalIF":3.7,"publicationDate":"2026-06-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13573387/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148163435","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The world's longest running civil war and chronic childhood undernutrition in Myanmar: a propensity score matched analysis.","authors":"Dhiman Bhadra","doi":"10.1186/s41043-026-01341-7","DOIUrl":"10.1186/s41043-026-01341-7","url":null,"abstract":"<p><strong>Background: </strong>Childhood undernutrition remains a major public health challenge in low- and middle-income countries (LMICs), particularly in settings affected by armed conflict and fragility. Prolonged civil conflict disrupts livelihoods, food systems and service delivery, yet its nutritional consequences remain poorly quantified. This study assesses the association between regional exposure to armed conflict and chronic childhood undernutrition in Myanmar.</p><p><strong>Methods: </strong>We linked nationally representative data obtained from the 2015-16 Myanmar Demographic and Health Survey with conflict event records from the Uppsala Conflict Data Program (2010-2015). Administrative regions were classified as conflict-affected or conflict-insulated based on the spatio-temporal frequency of conflict-related fatalities. Using a propensity score matching (PSM) approach, we estimated the association between conflict exposure and stunting (height-for-age Z-score < -2 SD) among a sample of 3,792 children matched on the basis of various demographic, socioeconomic and environmental attributes using the Average Treatment Effect on the Treated (ATT). Robustness checks across alternative matching algorithms and covariate exposure classification were carried out as well as sensitivity analysis for unmeasured confounding.</p><p><strong>Results: </strong>The estimated ATT was 0.045 (95% bootstrap CI: 0.005-0.083), corresponding to a 4.5 percentage point higher prevalence of stunting among children residing in conflict-affected regions compared with matched children from conflict-insulated regions. As a secondary analysis, post-matching multivariable logistic regression yielded a 28% higher odds of stunting for the former group (95% CI 1.10-1.49). Exploratory subgroup analysis suggested more pronounced associations among children of mothers with no education or employment, from poorer households and without access to improved sanitation. Results were robust to alternative propensity score modeling frameworks and moderate levels of unmeasured confounding.</p><p><strong>Conclusions: </strong>Protracted armed conflict is strongly associated with child undernutrition in Myanmar, compounding existing inequalities and undermining progress toward national and global nutrition targets. Thus, strengthening conflict-sensitive nutrition programming, community-based service delivery and health system resilience is essential to protect vulnerable children in fragile and conflict-affected contexts as in Myanmar.</p>","PeriodicalId":15969,"journal":{"name":"Journal of Health, Population, and Nutrition","volume":" ","pages":""},"PeriodicalIF":3.7,"publicationDate":"2026-06-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13347874/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148156807","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Minimum acceptable diet and its associated factors among children aged 6-23months in rural households of South Ethiopia.","authors":"Kassahun Fikadu, Abinet Teshome, Zeleke Hailemariam","doi":"10.1186/s41043-026-01353-3","DOIUrl":"10.1186/s41043-026-01353-3","url":null,"abstract":"<p><strong>Background: </strong>Optimal nutrition throughout the first 1,000 days is critical for a child's development, but malnutrition remains a major issue in Ethiopia. The Minimum Acceptable Diet (MAD) is an important indication of nutritional quality in children aged 6-23 months, although its prevalence and determinants vary significantly across the country. The purpose of this study was to determine the prevalence of MAD and its related characteristics in Southern Ethiopia's rural Gamo Zone, to guide targeted local interventions.</p><p><strong>Methods: </strong>From July to September 2023, a community-based, cross-sectional study was undertaken in three rural areas with 1,479 mother-child (6-23 months) couples. Households were selected using a multistage sampling procedure. Data were gathered using a pre-tested, structured questionnaire on the KoboCollect app and analyzed with SPSS version 25. We employed bivariate and multivariable logistic regression to discover characteristics linked to MAD, with statistical significance established at p-value < 0.05.</p><p><strong>Results: </strong>Among children who had started complementary feeding, 41.1% (n = 595; 95% CI: 38.6, 43.7) received a MAD. Several factors were found in the multivariable analysis to be strongly connected with MAD achievement. These included the child's age (AOR = 1.52 for 12-17 months and AOR = 1.45 for 18-23 months), having a working father (AOR = 1.6), family food security (AOR = 2.11), mother postnatal care attendance (AOR = 2.16), and possessing a television or radio (AOR = 1.67).</p><p><strong>Conclusion: </strong>Less than half of the children in the study fulfilled the minimum requirement for an appropriate diet, indicating that optimal feeding practices were not followed. Interventions should prioritize strengthening postnatal care counseling, increasing household food security, and utilizing media channels for health education. Promoting father engagement and providing assistance to younger infants (6-11 months) is critical for enhancing child nutrition outcomes.</p>","PeriodicalId":15969,"journal":{"name":"Journal of Health, Population, and Nutrition","volume":" ","pages":""},"PeriodicalIF":3.7,"publicationDate":"2026-06-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13483854/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148150101","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Falls and the global burden of hip fractures in elderly: an integrated analysis of mendelian randomization and the global burden of disease study 2021.","authors":"Hualin Zeng, Huilong Zeng, Xiaoling Zheng, Kaibin Fang, Zhangsheng Dai, Xiaocong Lin","doi":"10.1186/s41043-026-01350-6","DOIUrl":"10.1186/s41043-026-01350-6","url":null,"abstract":"<p><strong>Background: </strong>Hip fracture in older adults is a leading traumatic cause of death in this population. Our study provides a comprehensive assessment of the burden of hip fracture among the elderly and, using multiple analytical approaches, demonstrates a strong association between falls and hip fracture in this age group.</p><p><strong>Methods: </strong>Using the Global Burden of Disease (GBD) database, we reported the disease burden and risk factors of hip fractures in older adults and analyzed the relationship between falls and the associated disease burden. We employed Mendelian randomization (MR) to estimate the causal relationships between various risk factors (including falls) and hip fractures in the elderly. Furthermore, we described the epidemiological trends and projected future incidence of fall-related hip fractures in this population.</p><p><strong>Results: </strong>In 2021, the global incidence of hip fractures in the elderly was 13,286,199 (9,285,138-18,354,164), with an ASIR of 1,311.94 (918.51-1,807.04). Based on the GBD study, in 2021 more than 90% of the age-standardized incidence, prevalence, and years-lived-with-disability rates for hip fractures in older adults were attributable to falls. Among all fall-related geriatric diseases, the ASIR of geriatric hip fractures is the highest, significantly exceeding that of other conditions. The MR findings revealed that falls are significantly associated with an increased risk of hip fractures in the elderly. In 2021, the global incidence of fall-related hip fractures in the elderly was 12,103,660 (8,116,663-17,145,727), with an ASIR of 1,201.05 (808.88-1,693.91). Based on the Joinpoint regression analysis, it can be observed that from 1990 to 2021, the AAPC for the global ASIR of fall-related hip fractures in the elderly was 0.33 (95% CI: 0.31 to 0.34), with a P-value of less than 0.05. Based on the BAPC model, the global number of incident cases of fall-related hip fractures in the elderly is projected to reach 40,833,020 by 2050, with an age-standardized incidence rate (ASIR) of 1,540.20 per 100,000.</p><p><strong>Conclusion: </strong>There is a close association between falls and hip fractures in the elderly. In recent years, fall-related hip fractures have resulted in a significant disease burden, and the epidemiological trend has been upward. In the future, fall-related hip fractures may continue to lead to an even more severe disease burden.</p>","PeriodicalId":15969,"journal":{"name":"Journal of Health, Population, and Nutrition","volume":" ","pages":""},"PeriodicalIF":3.7,"publicationDate":"2026-06-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13483485/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148150113","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Nutritional knowledge, sustainable food practices and food safety, in child and youth care facilities in KwaZulu-Natal, South Africa.","authors":"Mumsy Evidence Chibe, Carin Napier, Heleen Grobbelaar","doi":"10.1186/s41043-026-01343-5","DOIUrl":"10.1186/s41043-026-01343-5","url":null,"abstract":"<p><strong>Background: </strong>Child and Youth Care Centres (CYCCs) play an important role in providing nutritional support to disadvantaged children and youth. However, little is known about how food handlers apply national nutrition and food hygiene standards in resource-constrained CYCC settings in South Africa.</p><p><strong>Aim: </strong>The aim of the study was to examine food, nutrition, and hygiene practices among food handlers at CYCCs in KwaZulu-Natal Province of South Africa.</p><p><strong>Methodology: </strong>A qualitative exploratory research design was used in the study. Three online focus group discussions (FGDs) were conducted in August and September 2020, with 18 food handlers from two CYCCs participating. COVID-19 Alert Level 5 restrictions necessitated online FGDs. The discussions were audio-recorded, transcribed verbatim, and analysed thematically. Co-researchers' independent coding, peer debriefing, member checking, and safeguarding of an audit trail all assisted to assure trustworthiness.</p><p><strong>Results: </strong>The study revealed different levels of awareness about nutrition guidelines and food-based dietary guidelines, with a significant gap between knowledge and practical application. While participants exhibited a high level of awareness of food safety, hygiene, and storage practices, implementation was hindered by limited financial resources, inadequate nutrition instruction, a lack of standardised recipes, and insufficient access to hygiene supplies and personal protective equipment. Budget constraints significantly affected meal planning and dietary diversification.</p><p><strong>Conclusion: </strong>While food handlers in CYCCs have a basic understanding of food safety and cleanliness, they face systematic and structural impediments to effectively apply nutrition requirements. Strengthening practical nutrition training, improving resource allocation, and increasing institutional and policy support are critical for improving food, nutrition, and hygiene practices and promoting improved health outcomes for children in CYCCs.</p>","PeriodicalId":15969,"journal":{"name":"Journal of Health, Population, and Nutrition","volume":" ","pages":""},"PeriodicalIF":3.7,"publicationDate":"2026-05-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13479415/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148101350","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}