Journal of Indian Society of Periodontology最新文献

{"title":"Alterations in macrophage polarization play a key role in control and development of periodontal diseases.","authors":"Mariane Cristina Sloniak, Ana Paula Lepique, Laís Yumi Souza Nakao, Cristina Cunha Villar","doi":"10.4103/jisp.jisp_75_23","DOIUrl":"10.4103/jisp.jisp_75_23","url":null,"abstract":"<p><p>Periodontitis is a chronic inflammatory disease driven by complex interplays between a dysbiotic oral microbiome and a dysregulated host inflammatory response that results in the destruction of the tooth-supporting apparatus. Among the inflammatory cells involved in the pathogenesis of periodontitis, macrophages are recruited early on to sites of periodontal infection. These cells can polarize in different phenotypes that mediate the initiation and resolution of inflammatory responses, as well as in tissue healing. Macrophage phenotypic plasticity is thought to play a critical role in the induction and resolution of inflammation and may be compromised in patients with chronic inflammatory diseases. Here, we reviewed the role of macrophage polarization in periodontal disease and therapy.</p>","PeriodicalId":15890,"journal":{"name":"Journal of Indian Society of Periodontology","volume":"27 6","pages":"578-582"},"PeriodicalIF":0.0,"publicationDate":"2023-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10906788/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140021901","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinical efficacy of 1% metformin gel around conventionally placed dental implants: A 9-month follow-up study.","authors":"Govardhani Krishnakumar, Sitamahalakshmi Koppu, Jampani Narendra Dev, Vajra Madhuri Songa, Lahari Buggapati, Radhika Mandrachalam","doi":"10.4103/jisp.jisp_534_22","DOIUrl":"10.4103/jisp.jisp_534_22","url":null,"abstract":"<p><strong>Aim: </strong>The study aimed to compare the clinical and radiographic outcomes of bone volume, density, and crestal bone levels in conventionally placed dental implants with and without local application of 1% metformin (MF) gel using cone-beam computed tomography (CBCT) at 9 months.</p><p><strong>Materials and methods: </strong>Twenty implants were placed in 18 individuals, randomly divided into 2 groups where Group A received a local application of 1% MF gel along with implant placement. In contrast, Group B received implant placement alone. After thorough clinical examination and preoperative CBCTs, implants were placed under aseptic conditions. Patients were recalled at 3 and 9 months after surgery. Implants were functionally loaded by the end of 3^rd month. Soft-tissue parameters such as modified plaque index and modified sulcular bleeding index were recorded along with CBCT evaluation to assess the crestal bone loss, bone density measurement, and bone volume, postoperatively. Fisher's extract test, independent and paired <i>t</i>-test, and Bonferroni analysis were used to determine statistical significance with <i>P</i> ≤ 0.05.</p><p><strong>Results: </strong>There was no discernible difference between the groups regarding soft-tissue parameters, bone density, and crestal bone levels. However, comparing bone volume between the test and control groups at 9 months was statistically significant. The test group with 1% MF gel showed increased bone volume around the implant.</p><p><strong>Conclusion: </strong>The data obtained were strong enough to suggest that 1% MF gel administered locally can increase peri-implant bone volume, possibly due to its additional property favoring osteoblastic stimulation and proliferation.</p>","PeriodicalId":15890,"journal":{"name":"Journal of Indian Society of Periodontology","volume":"27 6","pages":"626-635"},"PeriodicalIF":0.0,"publicationDate":"2023-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10906785/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140021959","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Zimmermann-Laband syndrome-associated hereditary gingival fibromatosis.","authors":"Jaishree Tukaram Kshirsagar, Kalaiselvan Dharani, Priyangha Thangavel","doi":"10.4103/jisp.jisp_582_22","DOIUrl":"10.4103/jisp.jisp_582_22","url":null,"abstract":"<p><p>Hereditary gingival fibromatosis (HGF) is an uncommon slow-growing fibrous overgrowth characterized by connective tissue accumulation. It presents as an isolated feature or as a manifestation of any syndrome. Various syndromes associated with HGF are inherited by autosomal dominant/recessive/X-linked traits. Zimmermann-Laband syndrome (ZLS) is a rare, autosomal dominant inherited disease manifested with gingival fibromatosis (GF), nose and ears abnormalities, and hypoplastic/dysplastic nails or terminal phalanges of hand and feet. Although the pattern of inheritance was found to be both autosomal dominant and recessive traits, the molecular basis is still unclear. This report presents a possible case of ZLS-associated HGF in a 25-year-old female patient who presents with GF, hypertrichosis, and other syndrome-related features. Her father was similarly affected whereas her mother and sibling were asymptomatic. The patient and her family members were explained about the condition and surgical periodontal therapy was carried out for the patient to improve esthetics and was followed up regularly. Esthetics was significantly improved and no recurrence was noted at the end of 6 months.</p>","PeriodicalId":15890,"journal":{"name":"Journal of Indian Society of Periodontology","volume":"27 6","pages":"645-650"},"PeriodicalIF":0.0,"publicationDate":"2023-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10906793/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140021970","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Communicate……Collaborate…….Emulate……….","authors":"Dharmarajan Gopalakrishnan","doi":"10.4103/jisp.jisp_528_23","DOIUrl":"https://doi.org/10.4103/jisp.jisp_528_23","url":null,"abstract":"","PeriodicalId":15890,"journal":{"name":"Journal of Indian Society of Periodontology","volume":"27 6","pages":"549"},"PeriodicalIF":0.0,"publicationDate":"2023-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10906794/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140021960","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation and comparison of three-dimensional finite element analysis of stress distribution in immediately placed and loaded conventional and customized three-dimensional printed dental implants.","authors":"Priya Saini, Vishakha Grover, Shaveta Sood, Ashish Jain, Parveen Kalra","doi":"10.4103/jisp.jisp_585_22","DOIUrl":"10.4103/jisp.jisp_585_22","url":null,"abstract":"<p><strong>Aim: </strong>The aim of this study was to evaluate and compare the stress distribution patterns in immediately placed and loaded conventional and customized three-dimensional (3D) printed dental implants by 3D finite element analysis.</p><p><strong>Materials and methods: </strong>Twelve 3D finite element models [Group A-3 models; Group B-9 models] with 72 test conditions which were modeled and compared from customized 3D printed dental implants [Group A] and 3 commercially available implant systems [Group B] (Straumann, Ankylos, and Astratech) using \"SolidWorks\". All models were embedded in extraction socket models of the maxillary central incisor (CI) and Canine (C), Mandibular 1^st Premolar. An occlusal loading by axial and nonaxial force of 100 N and 150 N at 30° and 45° was applied on the abutment using the \"ANSYS\" Suite. Customized 3D printed dental implant (Group A) for maxilla (Max.) CI, Max. C, and mandibular 1^st premolar (PM) socket model was compared with three commercial available dental implant systems (Group B) for Max. CI, Max. C, and mandible (Mand.) 1^st PM socket model to understand the stress distribution patterns.</p><p><strong>Results: </strong>With increasing oblique loads, von Mises stresses were reduced for the customized group as compared to conventional implants. Increased axial loads caused proportionate increase in the stresses for both groups, yet remained under the physiologic limits in all test conditions. Higher stresses were observed in cortical bone than in cancellous bone at bone-implant contact in general. Marked reduction in von Mises stress was observed at the boundary between compact and cancellous bone. Customized 3D printed implants performed better for oblique loads and comparable for axial load stress distribution in comparison to conventional implant systems in Max. CI and C, Mand. 1^st PM.</p><p><strong>Conclusion: </strong>Thus, customized 3D printed implants appear a promising alternative for immediately placed immediately loaded protocols, with additional benefits in specific clinical situations.</p>","PeriodicalId":15890,"journal":{"name":"Journal of Indian Society of Periodontology","volume":"27 6","pages":"590-599"},"PeriodicalIF":0.0,"publicationDate":"2023-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10906799/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140021963","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Localized juvenile spongiotic gingival hyperplasia.","authors":"Nitya Kala, Harikrishnan Prasad","doi":"10.4103/jisp.jisp_105_23","DOIUrl":"10.4103/jisp.jisp_105_23","url":null,"abstract":"<p><p>Localized juvenile spongiotic gingival hyperplasia (LJSGH) is a poorly understood entity and is probably a misnomer too. Although this lesion is thought to be predominantly found in young children, a significant number of cases have also been reported in adults. A 41-year-old female patient presented with an erythematous, velvety-appearing gingival mass in the mandibular anterior region. The lesion was recurrent in nature, although it was asymptomatic. A diagnosis of LJSGH was made after correlating the clinical and histopathological features. A literature search revealed that a large number of cases have been reported in adults, some as old as 87 years old. There seems to be no gender predilection, and the lesion is frequently noticed in relation to maxillary anterior gingiva. Recurrence is a characteristic feature of this lesion, although its etiology and pathogenesis are poorly understood till date. Since it has a unique behavior in terms of high recurrences, dentists and periodontists need to be made aware about spongiotic gingival hyperplasia since the lesion may be mistaken for common reactive lesions.</p>","PeriodicalId":15890,"journal":{"name":"Journal of Indian Society of Periodontology","volume":"27 6","pages":"642-644"},"PeriodicalIF":0.0,"publicationDate":"2023-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10906789/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140021966","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"One step at a time: How so ever baby, it may be.","authors":"Ashish Jain","doi":"10.4103/jisp.jisp_545_23","DOIUrl":"https://doi.org/10.4103/jisp.jisp_545_23","url":null,"abstract":"","PeriodicalId":15890,"journal":{"name":"Journal of Indian Society of Periodontology","volume":"27 6","pages":"550-551"},"PeriodicalIF":0.0,"publicationDate":"2023-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10906791/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140021967","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"<i>In vivo</i> efficacy of 2% povidone iodine, chlorhexidine gluconate, and herbal extract mouthwash on SARS-CoV-2 viral load in saliva: A randomized clinical trial.","authors":"Sayana Nazrine, Ritesh Kulal, B M Shivaprasad, Nimmi Janardhanan","doi":"10.4103/jisp.jisp_469_22","DOIUrl":"10.4103/jisp.jisp_469_22","url":null,"abstract":"<p><strong>Background: </strong>One of the major techniques to reduce the transmission rate of COVID-19 would be to decrease the viral titers of SARS-CoV-2 in the saliva of infected patients and it is particularly useful in a dental setting. The present study evaluated the change in salivary viral load of COVID-19 patients using povidone iodine (PI), chlorhexidine (CHX), and an herbal extract (RightSure^®) oral antiviral herbal mouthwash (HM) at clinically recommended duration and concentrations.</p><p><strong>Materials and methods: </strong>Thirty individuals with SARS-CoV-2 were randomly allocated to three groups: (1) Group 1, PI mouthwash; (2) Group 2, CHX mouthwash; and (3) Group 3, HM mouthwash. A baseline salivary throat sample was collected from all the participants who were later instructed to rinse with their respective mouthwash for 30 s. A second salivary sample was collected 30 min after rinsing. The SARS-CoV-2 viral load was analyzed using real-time reverse-transcription polymerase chain reaction wherein the cyclic threshold (Ct) values were evaluated.</p><p><strong>Results: </strong>Independent <i>t</i>-test analysis reported a statistically significant difference concerning the PI group (before-after comparison) (<i>P</i> < 0.05). The rest of the two study groups failed to report any significant difference in the nucleocapsid gene and open reading frame 1a gene levels.</p><p><strong>Conclusion: </strong>While all three types of mouthwash increased the Ct values, a statistically significant difference was observed with PI mouthwash, indicating that it might potentially reduce the spread of the SARS-CoV-2 virus, especially via aerosol but further studies with larger sample size and longer follow-up periods are required to investigate this relationship.</p>","PeriodicalId":15890,"journal":{"name":"Journal of Indian Society of Periodontology","volume":"27 6","pages":"607-611"},"PeriodicalIF":0.0,"publicationDate":"2023-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10906800/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140021900","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Tilapia fish waste: An asset for tissue engineering - A review.","authors":"Shalini Mundra, Preetha J Shetty, Neetha J Shetty","doi":"10.4103/jisp.jisp_395_22","DOIUrl":"10.4103/jisp.jisp_395_22","url":null,"abstract":"<p><p>Fisheries and aquaculture output have exploded due to an alarming increase in consumption due to the global understanding of the nutritional advantages of fish. Inadvertently, the methods produce a massive amount of fish waste, posing a serious environmental threat. Recycling this waste has now become a major point of controversy that must be resolved. It is critical to emphasize the utility of discarded marine by-products for the creation of high-value commodities such as marine collagen (MC), which can be considered a sustainable solution. Because of its biocompatibility, biodegradability, safety, minimal immunogenicity, and low production costs, MC has various benefits over terrestrial collagen. Many academics have recently become interested in the use of MC as a scaffold. This review focuses on the intriguing contribution of MC in the production of MC-based scaffolds.</p>","PeriodicalId":15890,"journal":{"name":"Journal of Indian Society of Periodontology","volume":"27 6","pages":"568-577"},"PeriodicalIF":0.0,"publicationDate":"2023-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10906792/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140021969","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Actinomycosis of periodontium, mimicking gingival enlargement - A case report and its management.","authors":"Renganath Murugan Jeyasree, Thamil Selvan Muthuraj, Gomakumar Kanakasabhapathi Usha, Jacob Raja","doi":"10.4103/jisp.jisp_63_23","DOIUrl":"10.4103/jisp.jisp_63_23","url":null,"abstract":"<p><p>Gingival abscess is a localized, acute inflammatory lesion which is caused by various factors that include microbial plaque infection, foreign body impaction, and trauma. Management includes a simple incision and draining of the purulent exudate along with systemic antibiotics in most of the cases. This article reports a case of a 16-year-old female patient, with a chief complaint of painful and swollen gums in her lower right front tooth region of the jaw along with fever for the past 5 days. Emergency treatment of abscess drainage was done on day 1. On 5^th day of review, the case presented with persistent signs of gingival inflammation in relation to 43 to 41. Considering the provisional diagnosis as dentigerous cyst with persistent gingival abscess, definitive treatment was performed by transalveolar extraction of the impacted canine and debridement of the osseous lesion. The histologic analysis of the lesion exhibited foci of eosinophilic coagulum-like areas with epicentric and radiating filamentous appearance at the periphery, which is suggestive of an inflamed dentigerous cyst with actinomycosis infection of periodontium.</p>","PeriodicalId":15890,"journal":{"name":"Journal of Indian Society of Periodontology","volume":"27 6","pages":"651-654"},"PeriodicalIF":0.0,"publicationDate":"2023-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10906796/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140023969","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}