Journal of Indian Society of Periodontology最新文献

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Assessment of peri-implant tissues in posterior implants placed using flapless approach: A clinicoradiographic study. 采用无瓣法植入后牙种植体的种植体周围组织评估:临床放射学研究
Journal of Indian Society of Periodontology Pub Date : 2024-03-01 Epub Date: 2024-08-31 DOI: 10.4103/jisp.jisp_457_23
Pranjali Vijaykumar Bawankar, Abhay Pandurang Kolte, Rajashri Abhay Kolte
{"title":"Assessment of peri-implant tissues in posterior implants placed using flapless approach: A clinicoradiographic study.","authors":"Pranjali Vijaykumar Bawankar, Abhay Pandurang Kolte, Rajashri Abhay Kolte","doi":"10.4103/jisp.jisp_457_23","DOIUrl":"https://doi.org/10.4103/jisp.jisp_457_23","url":null,"abstract":"<p><strong>Background: </strong>It is important to prognosticate the hard- and soft-tissue alterations in immediate and delayed implants, as inadequacy can lead to complications affecting the long-term survival of the implant. Therefore, the purpose of this study was to evaluate and compare the hard- and soft-tissue changes in immediate and delayed posterior implants with a flapless approach.</p><p><strong>Materials and methods: </strong>With an equal allocation ratio, the study included 46 patients requiring implant treatment in the posterior segment, including the premolars and molars. Group 1 consisted of patients with immediate implants, whereas Group 2 consisted of patients who received delayed implants. The clinical parameters, including plaque index (PI), gingival index, modified sulcus bleeding index, probing depth, and soft-tissue assessment using the Testori esthetic score (TS), were evaluated at baseline, 3, 6, 9, and 12 months. Hard-tissue parameters, such as buccal bone thickness (BBT), crestal bone height (CBH), and ridge width, were evaluated radiographically with cone-beam computed tomography at baseline and 12 months posttherapy.</p><p><strong>Results: </strong>Intragroup comparisons in both the groups showed significant differences in PI, probing pocket depth, and TS over time (<i>P</i> = 0.00). The mean BBT at the crest in delayed implants (1.76 ± 0.24) significantly reduced after 12 months compared to immediate implants. A significantly higher TS score was observed after 12 months in both the groups.</p><p><strong>Conclusion: </strong>A significant difference in TS scores after 12 months was found between the two groups, with better esthetics in Group 1 compared to Group 2. However, no significant changes in BBT or CBH were observed after 12 months in Group 1.</p>","PeriodicalId":15890,"journal":{"name":"Journal of Indian Society of Periodontology","volume":"28 2","pages":"197-203"},"PeriodicalIF":0.0,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11472978/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142467389","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Together for better oral health: Communication, collaboration, commitment. 携手改善口腔健康:沟通、合作、承诺。
Journal of Indian Society of Periodontology Pub Date : 2024-03-01 Epub Date: 2024-08-31 DOI: 10.4103/jisp.jisp_303_24
Ashish Jain
{"title":"Together for better oral health: Communication, collaboration, commitment.","authors":"Ashish Jain","doi":"10.4103/jisp.jisp_303_24","DOIUrl":"https://doi.org/10.4103/jisp.jisp_303_24","url":null,"abstract":"","PeriodicalId":15890,"journal":{"name":"Journal of Indian Society of Periodontology","volume":"28 2","pages":"155"},"PeriodicalIF":0.0,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11472969/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142467379","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Serum 25 hydroxycholecalciferol in periodontitis patients with type 2 diabetes mellitus - A socioeconomic and clinicobiochemical study in Chhattisgarh. 恰蒂斯加尔邦 2 型糖尿病牙周炎患者血清 25 羟基胆钙化醇--一项社会经济和临床生物化学研究。
Journal of Indian Society of Periodontology Pub Date : 2024-03-01 Epub Date: 2024-08-31 DOI: 10.4103/jisp.jisp_349_23
M P Gazala, Supriya Mishra, Vineeta Gupta, Waheda Rahman, Nupoor Khiraiya, Sheetal Dahiya
{"title":"Serum 25 hydroxycholecalciferol in periodontitis patients with type 2 diabetes mellitus - A socioeconomic and clinicobiochemical study in Chhattisgarh.","authors":"M P Gazala, Supriya Mishra, Vineeta Gupta, Waheda Rahman, Nupoor Khiraiya, Sheetal Dahiya","doi":"10.4103/jisp.jisp_349_23","DOIUrl":"https://doi.org/10.4103/jisp.jisp_349_23","url":null,"abstract":"<p><strong>Background: </strong>Very few studies have examined the impact of the concurrent presence of periodontitis (PD) and type 2 diabetes mellitus (T2DM) on serum Vitamin D levels, particularly in developing nations like India, and needs further investigation.</p><p><strong>Aim: </strong>This study aims to assess the relationship between serum Vitamin D values and PD in T2DM patients and to study the correlation between socioeconomic and demographic variables that influence the serum Vitamin D levels and the extent of PD in patients with T2DM.</p><p><strong>Materials and methods: </strong>This was a cross-sectional, hospital-based research. Medical, dental, and diet histories were obtained from the participants, and their socioeconomic status (SES) was determined. Clinical parameters - plaque index (PI), gingival index (GI), sites with gingival bleeding, probing pocket depth (PPD), and clinical attachment level (CAL) were compared among three groups -patients with generalized Stage III Grade B PD with T2DM (n=35), patients with generalized stage III Grade B PD (n=35) and healthy controls (n=35) and the clinical parameters - plaque index(PI), gingival index(GI), sites with gingival bleeding, probing pocket depth(PPD), and clinical attachment level(CAL) were measured. Biochemical tests included the evaluation of serum 25-hydroxyvitamin D (25[OH] D) and hemoglobin A1C (HbA1c) levels.</p><p><strong>Statistical analysis: </strong>Periodontal and biochemical parameters were compared using a one-way analysis of variance across the three groups. The association between clinical parameters, SES, and 25(OH)D was examined using Pearson's correlation coefficient test and linear regression analysis.</p><p><strong>Results: </strong>The serum 25(OH)D levels were lowest in the subjects with generalized Stage III Grade B PD with T2DM (13.54 ± 3.31 ng/mL). Furthermore, there was a significant (<i>P</i> < 0.01) negative correlation between serum 25(OH)D and periodontal parameters, PI (-0.442), PPD (-0.474), CAL (-0.459), sites with gingival bleeding (-0.354), and GI (-0.346) among the groups. The regression analyses showed that an increase in periodontal parameters (PI, GI, PPD, and CAL) and a higher HbA1c was linked to a lower 25(OH)D. However, the periodontal parameters and 25(OH)D levels showed no correlation with socioeconomic and demographic parameters in the study.</p><p><strong>Conclusion: </strong>Serum Vitamin D values are negatively influenced by the synergistic effect of PD and T2DM or by the presence of PD alone. However, the association of SES on serum Vitamin D values in individuals with PD and T2DM or PD alone could not be demonstrated.</p>","PeriodicalId":15890,"journal":{"name":"Journal of Indian Society of Periodontology","volume":"28 2","pages":"216-223"},"PeriodicalIF":0.0,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11472963/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142467377","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Efficacy of allogenic bone block graft in maxillary alveolar ridge reconstruction: A systematic review. 上颌骨牙槽嵴重建中异体骨块移植的疗效:系统综述。
Journal of Indian Society of Periodontology Pub Date : 2024-03-01 Epub Date: 2024-08-31 DOI: 10.4103/jisp.jisp_337_23
Aishwarya Ramkishan Purohit, Rajashri Abhay Kolte, Abhay Pandurang Kolte, Vrushali Nilesh Lathiya
{"title":"Efficacy of allogenic bone block graft in maxillary alveolar ridge reconstruction: A systematic review.","authors":"Aishwarya Ramkishan Purohit, Rajashri Abhay Kolte, Abhay Pandurang Kolte, Vrushali Nilesh Lathiya","doi":"10.4103/jisp.jisp_337_23","DOIUrl":"https://doi.org/10.4103/jisp.jisp_337_23","url":null,"abstract":"<p><strong>Background: </strong>The purpose of this systematic review was to assess the efficiency of allogenic bone block grafts for maxillary alveolar ridge reconstruction.</p><p><strong>Materials and methods: </strong>An electronic literature search was conducted using the PubMed, Cochrane Library, and Google Scholar databases. In addition, manual searching was done. Randomized controlled trials (RCTs) and prospective clinical trials (non-RCTs) up to December 2022, presenting the outcomes of allogenic bone blocks in maxillary alveolar ridge reconstruction, were identified. The rate of resorption, survival rate of implants, and formation of new bone following ridge augmentation were the outcome parameters. The quality assessment of the studies included was done using Joanna Briggs Institute Critical Appraisal Tool.</p><p><strong>Results: </strong>A total of 13 studies that matched the inclusion criteria were included. The average rate of bone resorption ranged from 0.2 to 29.2 mm, with an implant survival rate of 96.87% across the included investigations. On an average, 25.83 mm (18.6-33/mm) of new mature compact osseous tissue was discovered, including viable osteocytes in close contact with the remnant cancellous bone.</p><p><strong>Conclusion: </strong>According to the results of the current systematic review, using allogenic bone block graft for reconstruction of atrophic maxillae appears to be an effective and reliable bone substitute for reconstruction of atrophic maxillae.</p>","PeriodicalId":15890,"journal":{"name":"Journal of Indian Society of Periodontology","volume":"28 2","pages":"176-184"},"PeriodicalIF":0.0,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11472974/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142467395","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Spontaneous postoperative bleeding after periodontal procedure: An alarming sign of bleeding disorder. 牙周手术后自发性出血:出血性疾病的警示信号
Journal of Indian Society of Periodontology Pub Date : 2024-03-01 Epub Date: 2024-08-31 DOI: 10.4103/jisp.jisp_308_23
Shivani Mishra, Madhu Singh Ratre, Parul Jain
{"title":"Spontaneous postoperative bleeding after periodontal procedure: An alarming sign of bleeding disorder.","authors":"Shivani Mishra, Madhu Singh Ratre, Parul Jain","doi":"10.4103/jisp.jisp_308_23","DOIUrl":"https://doi.org/10.4103/jisp.jisp_308_23","url":null,"abstract":"<p><p>The prevalence of inherited bleeding disorders (BDs) is low in the general population (10-20 per 100,000 individuals), particularly hemophilia B cases, which may remain undiagnosed for a very long time until exposed to some surgical procedure. The dental professional must be aware of the possibility that patients with no previous history of abnormal bleeding may manifest their first bleeding episode in the dental office. Particularly as periodontists, we often encounter patients with bleeding gums and severe bleeding complications may precipitate while performing routine periodontal procedures. Hence, we must have a thorough knowledge of BDs and their management in challenging hemorrhagic situations. Management of such patients necessitates a multidisciplinary approach by involving the patient's hematologist and advanced laboratory facilities. The present case report is an attempt to discuss the diagnosis and management of a bleeding episode that occurred post periodontal flap surgery in an undiagnosed hemophilia B patient.</p>","PeriodicalId":15890,"journal":{"name":"Journal of Indian Society of Periodontology","volume":"28 2","pages":"258-261"},"PeriodicalIF":0.0,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11472971/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142467378","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Comparative clinical evaluation of the stability of implants using double acid etching treatment with and without the addition of fluoride solution: A randomized clinical trial. 使用含氟溶液和不含氟溶液的双酸蚀刻治疗种植体稳定性的临床对比评估:随机临床试验。
Journal of Indian Society of Periodontology Pub Date : 2024-03-01 Epub Date: 2024-08-31 DOI: 10.4103/jisp.jisp_52_23
Fernando Luiz Kaesemodel Hoppe, Márcio de Carvalho Formiga, Gislaine Fernandes Felipe Garcia, Rafael Manfro, Marcelo Carlos Bortoluzzi
{"title":"Comparative clinical evaluation of the stability of implants using double acid etching treatment with and without the addition of fluoride solution: A randomized clinical trial.","authors":"Fernando Luiz Kaesemodel Hoppe, Márcio de Carvalho Formiga, Gislaine Fernandes Felipe Garcia, Rafael Manfro, Marcelo Carlos Bortoluzzi","doi":"10.4103/jisp.jisp_52_23","DOIUrl":"https://doi.org/10.4103/jisp.jisp_52_23","url":null,"abstract":"<p><strong>Background: </strong>Osseointegration depends on primary stability, and further, implant surface modifications may improve secondary stability. This randomized clinical trial evaluates whether adding a fluoride solution enhances the implant stability.</p><p><strong>Materials and methods: </strong>Stability of dental implants with two different types of surface treatments was compared utilizing resonance frequency analysis (RFA). Twelve patients were recruited: eight females and four males with an average age of 58.3 years and they received either double acid etched implants (control: Porus Implant, Sistema Conexão) and double acid etched implants containing fluoride on their surfaces (test: Porus Nano Implant, Sistema Conexão). Each patient received one implant from the test category and another implant from the control category, resulting in 24 implants in this study. RFA, utilizing Osstell was used to assess the implant stability, immediately after the placement of implant and 15, 30 and 45 days post-implant placement.</p><p><strong>Results: </strong>At the initial time, there was no difference between the test and control groups regarding the ISQ. However, after 15, 30, and 45 days, ISQ values for the test group were significantly higher than the control group. When using implants without fluoride addition, it was observed that after 15 days, the ISQ values were lower than those found at the initial time, but after 30 days, values matched the initial. Concerning the test group results, the ISQ values from T0 (immediately after implant placement) to T3 (45 days after implant placement) always increased from every period of evaluation.</p><p><strong>Conclusions: </strong>It was concluded that double acid etched implants with surfaces containing fluoride solution increases the implant stability quotient, compared to implants with fluoride-free double acid etched surfaces.</p>","PeriodicalId":15890,"journal":{"name":"Journal of Indian Society of Periodontology","volume":"28 2","pages":"185-191"},"PeriodicalIF":0.0,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11472973/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142467392","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Osteogenic assessment of leukocyte platelet-rich fibrin and injectable platelet-rich fibrin in the human osteosarcoma MG - 63 cell line in chronic periodontitis patients: An in vitro study. 白细胞富血小板纤维蛋白和可注射富血小板纤维蛋白在慢性牙周炎患者人骨肉瘤 MG - 63 细胞系中的成骨作用评估:体外研究。
Journal of Indian Society of Periodontology Pub Date : 2024-03-01 Epub Date: 2024-08-31 DOI: 10.4103/jisp.jisp_503_23
A Sheryl Dolly, Prem Blaisie Rajula, P L Ravi Shankar, S Lochini, Mohamed Rashik, Sindhujaa Raja
{"title":"Osteogenic assessment of leukocyte platelet-rich fibrin and injectable platelet-rich fibrin in the human osteosarcoma MG - 63 cell line in chronic periodontitis patients: An <i>in vitro</i> study.","authors":"A Sheryl Dolly, Prem Blaisie Rajula, P L Ravi Shankar, S Lochini, Mohamed Rashik, Sindhujaa Raja","doi":"10.4103/jisp.jisp_503_23","DOIUrl":"https://doi.org/10.4103/jisp.jisp_503_23","url":null,"abstract":"<p><strong>Background: </strong>The burgeoning interest in implant and regenerative dental care has led to a notable upsurge in the utilization of regenerative modalities. The intent of the present investigation was to evaluate the osteogenic ability of two different concentrated platelet groups at various concentrations in the human osteosarcoma MG-63 cell line.</p><p><strong>Materials and methods: </strong>Blood samples from 21 volunteers with chronic periodontitis were collected which were then centrifuged in accordance with the protocols of Choukroun <i>et al</i>. and Miron <i>et al</i>. to produce leukocyte- and platelet-rich fibrin (L-PRF) and injectable platelet-rich fibrin (I-PRF), respectively. Following MG-63 cell culture, the osteogenic ability of 0, 4%, and 20% concentrations of both L-PRF and I-PRF were determined using the real-time polymerase chain reaction assay.</p><p><strong>Results: </strong>The results showed that 20% I-PRF (1.52 ± 0.24) and 4% L-PRF (1.42 ± 0.37) had the highest amount of bone morphogenetic protein 2 and osteocalcin, respectively.</p><p><strong>Conclusion: </strong>I-PRF appears to promote the initial differentiation of cells.</p>","PeriodicalId":15890,"journal":{"name":"Journal of Indian Society of Periodontology","volume":"28 2","pages":"192-196"},"PeriodicalIF":0.0,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11472965/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142467374","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Applications of a minimally invasive roll flap technique in peri-implant soft-tissue augmentation - A case series. 微创卷皮瓣技术在种植体周围软组织增量中的应用--病例系列。
Journal of Indian Society of Periodontology Pub Date : 2024-03-01 Epub Date: 2024-08-31 DOI: 10.4103/jisp.jisp_274_23
Mihir Raghavendra Kulkarni, Anjali Mahesh Chhabariya, Shiphalika Sinha, L Sahana, Anushtha Jain
{"title":"Applications of a minimally invasive roll flap technique in peri-implant soft-tissue augmentation - A case series.","authors":"Mihir Raghavendra Kulkarni, Anjali Mahesh Chhabariya, Shiphalika Sinha, L Sahana, Anushtha Jain","doi":"10.4103/jisp.jisp_274_23","DOIUrl":"https://doi.org/10.4103/jisp.jisp_274_23","url":null,"abstract":"<p><p>Deficiency of peri-implant tissue contours is commonly seen due to the process of alveolar ridge resorption after tooth loss. Minor deficiencies can be effectively managed by soft-tissue augmentation procedures to create a more biomimetic tissue contour. The minimally invasive roll technique is a modification of the palatal roll-flap technique and can be carried out at both stages of implant surgery. In this technique, the crestal keratinized tissue is marked and de-epithelialized using a circular partial-thickness incision. The crestal connective tissue is then reflected using a lingual full-thickness semi-circular incision, keeping the buccal attachment intact. This buccal attachment serves as the pedicle. The crestal connective tissue is then rolled into a pouch on the buccal aspect of the ridge to obtain soft-tissue augmentation. The present case study documents the clinical results of the minimally invasive roll flap technique (MIRT) in three clinical scenarios, namely single-stage implant surgery, second-stage implant surgery, and anterior esthetic soft-tissue contouring. In all the cases, excellent soft-tissue contour and thickness has been obtained around dental implants. The MIRT is a simple and efficient technique for areas that require minor soft-tissue augmentation. The technique can be used both in the maxilla and the mandible and facilitates a suture-free surgery.</p>","PeriodicalId":15890,"journal":{"name":"Journal of Indian Society of Periodontology","volume":"28 2","pages":"262-267"},"PeriodicalIF":0.0,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11472964/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142467369","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Longterm success of implants: Supportive peri-implant care is the "MANTRA"?? 种植体的长期成功:种植体周围的支持性护理是 "MANTRA"?
Journal of Indian Society of Periodontology Pub Date : 2024-03-01 Epub Date: 2024-08-31 DOI: 10.4103/jisp.jisp_306_24
Baljeet Singh
{"title":"Longterm success of implants: Supportive peri-implant care is the \"MANTRA\"??","authors":"Baljeet Singh","doi":"10.4103/jisp.jisp_306_24","DOIUrl":"https://doi.org/10.4103/jisp.jisp_306_24","url":null,"abstract":"","PeriodicalId":15890,"journal":{"name":"Journal of Indian Society of Periodontology","volume":"28 2","pages":"151-152"},"PeriodicalIF":0.0,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11472976/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142467373","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Quantification of Porphyromonas gingivalis using real-time polymerase chain reaction in subjects suffering from chronic periodontitis with and without rheumatoid arthritis. 利用实时聚合酶链式反应对患有或未患有类风湿性关节炎的慢性牙周炎患者中的牙龈卟啉单胞菌进行定量。
Journal of Indian Society of Periodontology Pub Date : 2024-03-01 Epub Date: 2024-08-31 DOI: 10.4103/jisp.jisp_351_23
Anuradha Bhatsange, Ketan Rajput
{"title":"Quantification of <i>Porphyromonas gingivalis</i> using real-time polymerase chain reaction in subjects suffering from chronic periodontitis with and without rheumatoid arthritis.","authors":"Anuradha Bhatsange, Ketan Rajput","doi":"10.4103/jisp.jisp_351_23","DOIUrl":"https://doi.org/10.4103/jisp.jisp_351_23","url":null,"abstract":"<p><strong>Background: </strong><i>Porphyromonas gingivalis</i>, highly virulent bacteria, is said to play an important role in the pathogenesis of periodontal disease and rheumatoid arthritis (RA). Chronic periodontitis (CP) is a microbial-induced inflammatory disease leading to tooth loss if undetected and untreated. RA is a systemic inflammatory disease affecting the joints with subsequent morbidity and mortality. These two diseases share a common pathobiology. Although the presence of <i>P. gingivalis</i> has been investigated as a bridging link between these two diseases, its quantification has not been fully elicited. Hence, this case-control study primarily aimed at quantifying <i>P. gingivalis</i> using real-time quantitative polymerase chain reaction (qPCR) and secondarily assess the influence of age and gender on the clinical and biochemical parameters of these two diseases.</p><p><strong>Materials and methods: </strong>The study population consisted of 51 patients divided into two age groups, i.e., 35-55 and 55-76 years. Twenty-five patients belonged to the test group (RA with CP) and 26 to the control group (CP without RA). Both the groups were analyzed for quantification of <i>P. gingivalis</i> using the qPCR technique along with periodontal and biochemical parameters. The study also analyzed the influence of age and gender on clinical characteristics.</p><p><strong>Results: </strong><i>P. gingivalis</i> count was exponentially raised in younger females having CP with RA. Age had no effect on clinical variables in CP patients with and without RA. However, gender comparison revealed RA factor and erythrocyte sedimentation rate to be more sensitive for females with significant relationship.</p><p><strong>Conclusion: </strong><i>P. gingivalis</i> count increased exponentially in CP patients with RA compared to those without RA. Younger females harbored more <i>P. gingivalis</i>.</p>","PeriodicalId":15890,"journal":{"name":"Journal of Indian Society of Periodontology","volume":"28 2","pages":"210-215"},"PeriodicalIF":0.0,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11472980/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142467376","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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