Journal of Feline Medicine and Surgery最新文献

{"title":"Exposure of urine of domestic cats to different substrates: impact on urine specific gravity.","authors":"Ana Paula Prueza de Almeida Luna Alves, Leandro Zuccolotto Crivellenti, Sofia Borin-Crivellenti, Suzana Akemi Tsuruta, Lucas Vinicius Ribeiro de Sousa, Vinicius Souza Mendes, Yury Carantino Costa Andrade","doi":"10.1177/1098612X251314710","DOIUrl":"10.1177/1098612X251314710","url":null,"abstract":"<p><p>ObjectivesUrine specific gravity (USG) is a crucial indicator of renal function and is integral in the monitoring of renal disease progression. Although USG is a readily quantifiable parameter, the process of urine collection in cats can induce stress. Utilizing both hydrophobic and non-hydrophobic substrates in litter trays may reduce this stress and enhance owner compliance with urine collection protocols. This study investigated changes in USG as a result of exposing urine to different substrates over different time periods. A second objective was to assess the impact of other urine parameters, including microhematuria, proteinuria, pyuria, glycosuria, crystalluria and cylindruria, on USG within the context of the substrates used.MethodsA total of 34 cat urine samples were exposed to different substrates (a hydrophobic substrate, waterproof sand and aquarium gravel). Urine absorption and USG values were evaluated 10, 30, 60 and 120 mins after exposure.ResultsThe use of aquarium gravel as a substrate was deemed unsuitable because it absorbed the urine samples, thereby hindering sequential evaluations. In contrast, the hydrophobic substrate (Kit4Cat) showed no significant influence on USG. The non-absorbent waterproof sand (Fantastic Sand) significantly increased the USG values of cat urine during exposure periods of 60 mins and 120 mins.Conclusions and relevanceThe hydrophobic substrate used in this study did not interfere with USG monitoring for up to 120 mins.</p>","PeriodicalId":15851,"journal":{"name":"Journal of Feline Medicine and Surgery","volume":"27 7","pages":"1098612X251314710"},"PeriodicalIF":1.9,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12228917/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144567514","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Percutaneous cholecystostomy drain placement in cats: feasibility and safety of an ultrasound- and fluoroscopy-guided method.","authors":"Jasmin Ordobazari, Charlotte Pfeiffer, Adriano Wang Leandro, Ina Quadflieg, Holger A Volk, Georga T Karbe","doi":"10.1177/1098612X251336702","DOIUrl":"10.1177/1098612X251336702","url":null,"abstract":"<p><p>ObjectivesThe aim of the present study was to evaluate the feasibility and safety of percutaneous ultrasound- and fluoroscopy-guided cholecystostomy drain placement.MethodsAn experimental cadaveric study was conducted on 16 cat cadavers weighing between 2.5 and 6.4 kg. Two drain systems were tested for percutaneous ultrasound- and fluoroscopy-guided placement: the nephrostomy component of a subcutaneous urethral bypass system (SUB-nephrostomy drain) and a paediatric percutaneous access set (paediatric-nephrostomy drain). Ultrasound-guided cholecystocentesis was performed via the 8th-12th intercostal space. Using a Seldinger technique, a guidewire was advanced into the gallbladder over which the drains were then passed under fluoroscopic control. Protocol modification was required mid experiment. Gallbladders were filled via catheterisation of the common bile duct before cholecystocentesis. After fluoroscopy-confirmed cholecystostomy drain placement, CT scans were performed to assess drain position, iatrogenic organ injuries and leakage. Leak pressure testing was performed followed by anatomic dissection. Organ injuries were recorded and classified as minor, moderate or severe.ResultsSUB-nephrostomy drain placement was performed in 15 cats and placement into the gallbladder was feasible in two: one was passed before and one after technique modification. Paediatric-nephrostomy drain placement was tested in one cat. The gallbladder could not accommodate the drain size, placement was not feasible and the device was not further tested. A CT scan of the two cats with drain placement showed a moderate amount of free peritoneal contrast, no pleural space penetration and one liver injury. Leakage occurred at a pressure of 4.5 cm H₂O. For all drains, injuries recorded during anatomic dissection were to the liver, pleural space and gallbladder. The majority of injuries were classified as minor.Conclusions and relevancePercutaneous placement of cholecystostomy drains was not feasible with the method and devices tested. Further studies are needed to investigate alternative techniques in cats.</p>","PeriodicalId":15851,"journal":{"name":"Journal of Feline Medicine and Surgery","volume":"27 7","pages":"1098612X251336702"},"PeriodicalIF":1.9,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12227865/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144553739","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Physical rehabilitation of cats: 1. Common conditions benefiting from physiotherapy.","authors":"Mary Ellen Goldberg","doi":"10.1177/1098612X251334558","DOIUrl":"10.1177/1098612X251334558","url":null,"abstract":"<p><strong>Practical relevance: </strong>Physical rehabilitation (physiotherapy) involves restoring a patient's movement and function following an injury, illness or trauma. It can be used for acute and chronic conditions and, in some cases, the techniques are used as a preventive treatment. Some therapies can also provide pain relief, which can be especially helpful when analgesic drugs are contraindicated in a patient. In recent years, there has been increasing interest in the application of physiotherapy to small animals, and while physical rehabilitation has traditionally been used more commonly for canine than feline patients, as cats can benefit just as much as dogs, this trend is changing. A multidisciplinary team is involved and identifying when a cat is painful and prioritizing therapies accordingly is crucial.</p><p><strong>Clinical challenges: </strong>Cats are typically not accustomed to regular handling or restraint and tend to become uninterested and frustrated quickly, which means they are often perceived as poor candidates for physiotherapy referral. As well as a cat's temperament, there are physical factors that may limit or exclude particular therapies; for instance, a cat's level of cardiovascular health. There can also be much variation with the success of different therapies - what works well in one individual might have no effect in another.</p><p><strong>Aims: </strong>This article, the first in a two-part series, discusses the most common painful conditions in cats that can benefit from physical rehabilitation, as well as the importance of prioritizing the type of therapy depending on the individual patient. Part 2 discusses individual therapies and exercises for physical rehabilitation.</p>","PeriodicalId":15851,"journal":{"name":"Journal of Feline Medicine and Surgery","volume":"27 7","pages":"1098612X251334558"},"PeriodicalIF":1.9,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12227867/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144553740","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Physical rehabilitation of cats: 2. Treatment therapies and exercises.","authors":"Mary Ellen Goldberg","doi":"10.1177/1098612X251334555","DOIUrl":"10.1177/1098612X251334555","url":null,"abstract":"<p><strong>Practical relevance: </strong>Physical rehabilitation (physiotherapy) involves restoring a patient's movement and function following an injury, illness or trauma. It can be used for acute and chronic conditions and, in some cases, the techniques are used as a preventive treatment. Some therapies can also provide pain relief, which can be especially helpful when analgesic drugs are contraindicated in a patient. In recent years, there has been increasing interest in the application of physiotherapy to small animals, and while physical rehabilitation has traditionally been used more commonly for canine than feline patients, as cats can benefit just as much as dogs, this trend is changing. A multidisciplinary team is involved and identifying when a cat is painful and prioritizing therapies accordingly is crucial.</p><p><strong>Clinical challenges: </strong>Cats are not accustomed to regular handling or restraint and tend to become uninterested and frustrated quickly, which means they are often perceived as poor candidates for physiotherapy referral. As well as a cat's temperament, there are physical factors that may limit or exclude particular therapies; for instance, a cat's level of cardiovascular health. There can also be much variation with the success of different therapies - what works well in one individual might have no effect in another.</p><p><strong>Aims: </strong>This article, the second in a two-part series, discusses individual therapies and exercises for physical rehabilitation. This follows on from Part 1, which discusses the most common painful conditions in cats that can benefit from physical rehabilitation, as well as the importance of prioritizing the type of therapy depending on the individual patient.</p>","PeriodicalId":15851,"journal":{"name":"Journal of Feline Medicine and Surgery","volume":"27 7","pages":"1098612X251334555"},"PeriodicalIF":1.9,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12227875/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144553741","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Immunohistochemical evaluation of cyclooxygenase-2 expression in feline nasal malignant epithelial tumours.","authors":"Nicolas Diop, Aude M Canonne, Hélène Huet, Edouard Reyes-Gomez, Jérémy Béguin","doi":"10.1177/1098612X251314336","DOIUrl":"10.1177/1098612X251314336","url":null,"abstract":"<p><p>ObjectivesCyclooxygenase-2 (COX-2), a pivotal enzyme in the cyclooxygenase family, plays a critical role in carcinogenesis. While its expression is well documented in various neoplasms in humans and dogs, data on COX-2 expression in feline neoplasms, particularly nasal malignant epithelial tumours, is limited. This study aimed to evaluate COX-2 expression in feline nasal malignant epithelial tumours through immunohistochemistry. We hypothesised that these tumours would exhibit COX-2 expression, consistent with findings in humans and dogs.MethodsFormalin-fixed, paraffin-embedded biopsy samples from feline nasal malignant epithelial tumours were retrospectively analysed for COX-2 expression by immunohistochemistry. Biopsies from cats previously treated with non-steroidal anti-inflammatory drugs were excluded. Immunohistochemistry was performed with a monoclonal rabbit antibody, with feline renal macula densa cells serving as the positive control. The immunoreactive score (IRS) combined a semiquantitative estimation of immunolabelled neoplastic cells with labelling intensity. Scores in the range of 0-1 were classified as negative, 2-3 as low, 4-8 as intermediate and greater than 8 as high COX-2 expression levels.ResultsA total of 18 feline nasal biopsies (nine adenocarcinomas, seven carcinomas, one squamous cell carcinoma and one mucinous carcinoma) were included. Clinical signs included nasal discharge, sneezing, epistaxis and inspiratory dyspnoea. COX-2 expression was not detected in any case (IRS = 0). Follow-up data were available for 7/18 cats. The overall median survival time after diagnosis in our cohort was 667 days (range 0-1642).Conclusions and relevanceIn contrast to canine nasal malignant epithelial tumours, COX-2 expression was not observed in feline nasal malignant epithelial tumours. These results suggest species-specific differences in COX-2 expression in nasal malignant epithelial tumours. Further studies evaluating other carcinogenesis pathways, such as vascular endothelial growth factor or platelet-derived growth factor, seem crucial to better understand feline nasal malignant epithelial tumours and to improve their therapeutic management.</p>","PeriodicalId":15851,"journal":{"name":"Journal of Feline Medicine and Surgery","volume":"27 6","pages":"1098612X251314336"},"PeriodicalIF":1.9,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12177249/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144302236","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A retrospective descriptive study of colorectal large or intermediate cell lymphoma in cats managed with surgical resection and/or medical management.","authors":"Katerina Holenova, Petros Odatzoglou, Frances Taylor","doi":"10.1177/1098612X251338641","DOIUrl":"10.1177/1098612X251338641","url":null,"abstract":"<p><p>ObjectivesThe current standard-of-care treatment for feline gastrointestinal intermediate- or large-cell lymphoma is systemic chemotherapy. There is some evidence that feline lymphoma patients with a solitary gastrointestinal mass may benefit from excisional surgery followed by chemotherapy; however, most studies of feline gastrointestinal lymphoma combine various stages and anatomical sites of the disease. Studies indicating different behaviour of feline gastrointestinal lymphoma depending on its anatomical location have been published, and significantly longer survival times have been seen in canine colorectal lymphoma. The aim of the present study was therefore to describe the signalment, treatment and outcome of cats with intermediate- or large-cell lymphoma in the colorectal region.MethodsThe medical records of three veterinary hospitals were retrospectively searched for cats diagnosed with a colorectal intermediate- or large-cell lymphoma. The data were collected and subjected to a univariate analysis, and median values were calculated for each of the variables of interest. Median survival times were estimated using the Kaplan-Meier method.ResultsA total of 11 cats were included in the study, with the most common presenting signs being haematochezia, hyporexia, diarrhoea and weight loss. Different treatment strategies and their combinations were used, leading to an overall median survival time of 177 days, with a difference seen between chemotherapy only (29 days) and a combination of surgery and chemotherapy (972 days). Two cats treated with both surgery and chemotherapy were alive at more than 20 months after diagnosis.Conclusions and relevanceThis is the first study to describe specifically cases of cats with intermediate- to large-cell colorectal lymphoma. Even though the number of cases was limited because of the rarity of the disease, the data indicate multimodal treatment might be beneficial in these cases.</p>","PeriodicalId":15851,"journal":{"name":"Journal of Feline Medicine and Surgery","volume":"27 6","pages":"1098612X251338641"},"PeriodicalIF":1.9,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12206256/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144528239","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Retrospective study of biochemical profile changes in 93 cats with different hepatobiliary diseases.","authors":"Athena Kam, Jill E Maddison, Balazs Szladovits","doi":"10.1177/1098612X251335202","DOIUrl":"10.1177/1098612X251335202","url":null,"abstract":"<p><p>ObjectivesThis study aims to assess hepatic clinicopathological changes in cats with different hepatobiliary diseases and to assess whether specific serum biochemistry changes can help differentiate these diseases.MethodsA retrospective analysis was conducted on serum biochemistry data from 93 cats with hepatobiliary diseases and 80 control cats. Of the 93 cats with definitive diagnoses of hepatobiliary diseases, 22 had cholangitis, 14 had hepatic lipidosis, 18 had primary hepatic neoplasia confirmed via Tru-cut or laparotomic wedge biopsy and 39 had congenital portosystemic shunting (CPSS) confirmed by abdominal ultrasound. The biomarkers analysed were alanine aminotransferase (ALT), alkaline phosphatase (ALP), gamma glutamyl-transferase (GGT), total bilirubin and albumin.ResultsCats with hepatobiliary disease had significantly higher enzyme activities, total bilirubin concentrations and lower albumin concentrations compared with controls (<i>P</i> <0.01). Comparison between diseases showed that there were no differences in hepatobiliary biomarkers between cholangitis and neoplasia, despite cholangitis being an abnormality of bile ductules and neoplasia affecting hepatic parenchymal cells. GGT activities in cats with hepatic lipidosis showed no difference compared with controls. A significant increase in ALP activity was observed in CPSS cases (<i>P</i> <0.01); however, this difference disappeared when the analysis was restricted to age-matched controls.Conclusions and relevanceThis study provides the most recent corroboration of previous findings on clinical pathology changes in feline hepatobiliary disease, supporting research conducted over a decade ago with new data from a different geographical location. For example, the observation that a significant increase in ALP without an increase in GGT is highly suggestive of hepatic lipidosis, aligning with findings from a 1993 study conducted in North America. In addition, this study reinforced the importance of serum biochemistry as a useful tool in differentiating cats with hepatobiliary disease from those without; however, it also reaffirmed previous conclusions that serum biochemistry alone is insufficient for a definitive diagnosis, which instead must be based on a combination of patient history, clinical signs and ancillary diagnostic tests, such as ultrasound and tissue biopsy.</p>","PeriodicalId":15851,"journal":{"name":"Journal of Feline Medicine and Surgery","volume":"27 6","pages":"1098612X251335202"},"PeriodicalIF":1.9,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12141792/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144225679","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Body stalk anomalies and their relationship to amniotic band disruption complex in six cats.","authors":"Nieves Martín-Alguacil, José M Cozar, Luis Avedillo","doi":"10.1177/1098612X251341068","DOIUrl":"10.1177/1098612X251341068","url":null,"abstract":"&lt;p&gt;&lt;p&gt;ObjectivesThe aim of this study was to investigate the appearance of body stalk anomalies (BSAs) and amniotic band disruption complex (ABDC) in cats (&lt;i&gt;Felis catus&lt;/i&gt;), classify these congenital conditions using a system originally developed for humans and pigs, and provide new insights into the aetiopathogenesis.MethodsSix cats suspected of having BSAs and/or ABDC were examined. The classification system for BSA, which includes eight types, was applied to these cases. Detailed observations were made regarding physical deformities, presence of amniotic adhesions and degree of impairment. A comparative analysis with similar conditions in pigs and humans was carried out to highlight differences and similarities.ResultsTwo of the eight BSA classifications used in human and porcine congenital anomalies were detected in the six cats. In the studied cases, the degree of severity was lower than in pigs. The abnormalities associated with BSAs were attributed to the effect of amniotic bands on already formed organs or to the disruption of organ development, leading to a cascade of abnormal events.Conclusions and relevanceThis study is the first to describe and classify BSAs and ABDC in cats and provides valuable insights into these congenital anomalies. The findings highlight significant differences and similarities between cats and other species, particularly pigs. Understanding the aetiopathogenesis of these conditions is essential to improve clinical management and prognosis. Surgical correction and supportive care can improve the quality of life of affected cats, depending on the severity of the condition. Continued research and collaboration are essential to advance the prevention, diagnosis and treatment of BSAs and ABDC in cats, with wider implications for congenital anomalies across species.Plain language summaryThis study aims to explore body stalk anomalies (BSAs) and amniotic band disruption complex (ABDC) in cats (&lt;i&gt;Felis catus&lt;/i&gt;). It classifies these conditions using a system developed for humans and pigs and seeks to understand their causes and management in cats. Six cats with suspected BSAs and/or ABDC were examined. The classification system for BSA, which includes eight types, was applied to these cases. Observations focused on physical deformities, amniotic adhesions and the severity of the conditions. Comparisons were made with similar conditions in pigs and humans. Two of the eight BSA classifications used in human and porcine congenital anomalies were detected in the six cats. In this study, the severity of the condition in cats was lower compared with pigs. The abnormalities were caused by amniotic bands affecting already-formed organs or disrupting organ development, leading to a series of abnormal events. This is the first study to describe and classify BSAs and ABDC in cats. It provides new insights into these congenital conditions and highlights differences and similarities with other species. Surgical correction and ","PeriodicalId":15851,"journal":{"name":"Journal of Feline Medicine and Surgery","volume":"27 6","pages":"1098612X251341068"},"PeriodicalIF":1.9,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12188039/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144475518","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Adverse events after fecal microbiota transplantation in nine cats: a case series.","authors":"Mary Ann Lee, Tanner Slead, Jan Suchodolski, M Katherine Tolbert, Sina Marsilio","doi":"10.1177/1098612X251337274","DOIUrl":"10.1177/1098612X251337274","url":null,"abstract":"<p><p>This case series describes nine cases of fecal microbiota transplantation in cats and associated adverse events (AEs) from two tertiary referral hospitals. AEs were graded according to criteria established by the Veterinary Cooperative Oncology Group's Common Terminology Criteria for Adverse Events (VCOG-CTCAE v2) for clinical trials. Cats received 5-6 g/kg donor feces 2-6 times for chronic enteropathy (n = 4) or therapy-resistant diarrhea (n = 5). AEs included lethargy (n = 7), vomiting (n = 5), diarrhea (n = 5), weight loss (n = 5), inappetence (n = 5), dehydration (n = 5), abdominal pain (n = 2), gastroenterocolitis based on ultrasound (n = 2) and anorexia (n = 1). Temperatures of up to 103.4°F were noted but did not meet the criteria for AEs (>103.5°F). Cats responded to antimicrobials (metronidazole, marbofloxacin), anthelmintics (fenbendazole), supportive care with fluids, ondansetron and mirtazapine (n = 5), gabapentin (n = 2), pradofloxacin (n = 1) or self-resolved (n = 1). Positive response to fecal microbiota transplantation for the presenting complaint was seen in eight cats (seven complete, one partial and transient).Relevance and novel informationFecal microbiota transplantation is increasing in usage among companion animals. Fecal microbiota transplantations in cats have been rarely described in the literature as have AEs after administration. This case series represents the first description of AEs after fecal microbiota transplantation in cats.</p>","PeriodicalId":15851,"journal":{"name":"Journal of Feline Medicine and Surgery","volume":"27 5","pages":"1098612X251337274"},"PeriodicalIF":1.9,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12126621/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144180394","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Voluntary acceptance of nutrient-enriched water supplement and promotion of water intake in clinically dehydrated cats.","authors":"Maria Peralta, Amy Nichelason, Lauren Trepanier","doi":"10.1177/1098612X251334279","DOIUrl":"10.1177/1098612X251334279","url":null,"abstract":"<p><p>ObjectivesThe aim of this prospective observational study was to quantitate voluntary consumption of a nutrient-enriched water (NW) supplement and assess any improvements in serum biochemical values, clinical hydration assessments or quality of life (QoL) parameters in clinically dehydrated feline patients.MethodsA total of 13 stable, clinically dehydrated pet cats, for which outpatient management was deemed clinically appropriate by the attending veterinarian, completed the study between May and December 2023. Cats were offered NW based on body weight, along with ad libitum water. Fluid intake was measured, and changes in blood urea nitrogen and other biochemical measures of hydration, body weight, clinical hydration and owner-perceived QoL) survey scores were assessed at baseline and at 48 h.ResultsVoluntary NW intake (median 38.9 ml/kg/day) was significantly higher than ad libitum drinking water consumption (13.7 ml/kg/day; <i>P</i> = 0.005). Owners perceived the NW to be well accepted by their cats. Cats had a median total fluid intake of 47.2 ml/kg/day and every participating cat exceeded a target total fluid intake of 30 ml/kg/day. There were no changes in biochemical markers or body weight over 48 h of NW intake. Clinical assessments of hydration significantly improved (<i>P</i> <0.004), as did owner-perceived QoL (<i>P</i> = 0.001).Conclusions and relevanceClinically dehydrated pet cats voluntarily accepted the NW and consumed more NW than water. Median NW intake exceeded commonly prescribed feline subcutaneous fluid doses of 20 ml/kg/day, and both clinical hydration and owner-perceived QoL improved over the study duration. NW provides a well-tolerated, low-stress and voluntarily accepted method to promote fluid intake in feline patients.</p>","PeriodicalId":15851,"journal":{"name":"Journal of Feline Medicine and Surgery","volume":"27 5","pages":"1098612X251334279"},"PeriodicalIF":1.9,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12089729/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144094005","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}