Journal of Feline Medicine and Surgery最新文献

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Behaviors suggestive of pain: the perceptions and veterinary-related decisions of cat guardians in the USA. 暗示疼痛的行为:美国猫咪监护人的看法和兽医相关决定。
IF 1.9 2区 农林科学
Journal of Feline Medicine and Surgery Pub Date : 2024-10-01 DOI: 10.1177/1098612X241272885
Lori R Kogan, Jen Currin-McCulloch, Peter Hellyer
{"title":"Behaviors suggestive of pain: the perceptions and veterinary-related decisions of cat guardians in the USA.","authors":"Lori R Kogan, Jen Currin-McCulloch, Peter Hellyer","doi":"10.1177/1098612X241272885","DOIUrl":"10.1177/1098612X241272885","url":null,"abstract":"<p><strong>Objectives: </strong>The aim of the study was to assess cat guardians' concern levels and veterinary care decisions pertaining to behaviors that might signify pain before and after receiving brief pain-related educational information. The secondary aims were to evaluate cat guardians' perceptions of the usefulness of a modified version of the Colorado State University Feline Acute Pain Scale (CSU-FAPS) in identifying their cat's pain level, determining if they should take their cat to the veterinarian and describing their cat's pain to their veterinarian.</p><p><strong>Methods: </strong>Participants were recruited through Prolific. An electronic survey was created in Qualtrics and distributed via a link offered in Prolific.</p><p><strong>Results: </strong>A total of 362 surveys were completed by participants who resided in the USA and were the primary caretaker of at least one cat. Significant differences between participants' concern levels before and after pain-related educational information were found for two of the three scenarios. Significant differences were found between participants' veterinary-related behavior choices before and after pain-related educational information for all three scenarios. The most common reasons for not seeking immediate veterinary care included elements related to cost and stress for guardian and cat during veterinary visits. The majority of participants reported finding the CSU-FAPS useful for identifying their cat's pain level (90%), determining if they should take their cat to the veterinarian (86%) and describing their cat's pain to their veterinarian (92%).</p><p><strong>Conclusions and relevance: </strong>Guardians' interpretations of and subsequent actions to behaviors that might suggest pain carry great implications for feline health and wellbeing. After exposure to brief pain-related educational material, guardians in our study reported significant increases in stated concern related to their cat's change in behavior and intention to seek veterinary care. These findings suggest that even very brief pain-related educational material can have a positive impact on cat guardians' perceptions of feline behavior changes and increase the possibility they obtain appropriate veterinary care.</p>","PeriodicalId":15851,"journal":{"name":"Journal of Feline Medicine and Surgery","volume":null,"pages":null},"PeriodicalIF":1.9,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142390998","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Dietary phosphorus and renal disease in cats: where are we? 猫的膳食磷与肾病:进展如何?
IF 1.9 2区 农林科学
Journal of Feline Medicine and Surgery Pub Date : 2024-10-01 DOI: 10.1177/1098612X241283355
Jonathan Stockman
{"title":"Dietary phosphorus and renal disease in cats: where are we?","authors":"Jonathan Stockman","doi":"10.1177/1098612X241283355","DOIUrl":"https://doi.org/10.1177/1098612X241283355","url":null,"abstract":"<p><strong>Practical relevance: </strong>Phosphorus is an essential nutrient required for the normal function of every cell in the body and a deficiency in dietary phosphorus may lead to adverse effects. Conversely, high dietary phosphorus may cause kidney damage in otherwise healthy adult cats, particularly when provided in highly bioavailable forms and when the calcium-to-phosphorus ratio is low. For cats that have chronic kidney disease (CKD), phosphorus is the most important mineral in its pathogenesis and morbidity. As the disease progresses, elevated phosphorus may increase the risk of complications such as soft tissue mineralization, which can lead to a further decrease in renal function. Additionally, the hormones secreted in response to increased circulating phosphorus have harmful effects, such as bone resorption, and can cause cardiovascular pathology. Very low phosphorus diets can also be problematic in cats with early CKD, potentially leading to hypercalcemia.</p><p><strong>Clinical challenges: </strong>There is currently a lack of maximum safety limits for dietary phosphorus in accepted nutritional guidelines in North American and Europe, which makes it difficult to assess the safety of some higher phosphorus cat foods. Additionally, information regarding phosphorus bioavailability is unknown for many diets and there are no commercially available tests. Similarly, there is no consensus regarding phosphorus requirement and recommended intake in cats with International Renal Interest Society stage 1-4 CKD despite there being targets for serum phosphorus.</p><p><strong>Aims: </strong>This review evaluates dietary phosphorus in healthy cats and cats with renal disease, and describes how newer research is informing evolving clinical approaches in feline nutrition.</p><p><strong>Audience: </strong>The article is aimed at general practitioners, internal medicine specialists and veterinary nutritionists.</p><p><strong>Evidence base: </strong>Information provided in this article is drawn from the published literature.</p>","PeriodicalId":15851,"journal":{"name":"Journal of Feline Medicine and Surgery","volume":null,"pages":null},"PeriodicalIF":1.9,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142391007","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Retrospective description of the clinical use of chloramphenicol in client-owned cats: 12 cases (2015-2023). 对客户饲养的猫咪临床使用氯霉素情况的回顾性描述:12 个病例(2015-2023 年)。
IF 1.9 2区 农林科学
Journal of Feline Medicine and Surgery Pub Date : 2024-10-01 DOI: 10.1177/1098612X241254024
Vanessa Bruneau, Faye Hartmann, Katrina Viviano
{"title":"Retrospective description of the clinical use of chloramphenicol in client-owned cats: 12 cases (2015-2023).","authors":"Vanessa Bruneau, Faye Hartmann, Katrina Viviano","doi":"10.1177/1098612X241254024","DOIUrl":"https://doi.org/10.1177/1098612X241254024","url":null,"abstract":"<p><strong>Objectives: </strong>The study aimed to describe the clinical use of chloramphenicol in client-owned cats, examining the patient population, sites of infection, targeted pathogens, prescribed dosing regimen, outcomes and adverse effects.</p><p><strong>Methods: </strong>Between 2015 and 2023, a retrospective medical record review was undertaken to identify a case series of cats treated with chloramphenicol.</p><p><strong>Results: </strong>Twelve client-owned cats with complicated infections were treated with chloramphenicol at a median dose of 13.3 mg/kg (range 9.1-34.7) administered orally every 12 h for a median duration of 14.5 days. Within 30 days before starting chloramphenicol, 11/12 cats had received treatment with at least one antibiotic. The sites of infection included skin, urinary tract and multisystemic. Multidrug-resistant pathogens, for which no alternative oral antibiotic therapy was available, were commonly targeted. These included meticillin-resistant <i>Staphylococcus</i> species and multidrug-resistant <i>Enterococcus faecium</i>. Of the 12 cats treated with chloramphenicol, nine effectively achieved either bacteriologic or clinical cure. Chloramphenicol adverse effects were uncommon and limited to gastrointestinal upset, which was self-limiting or manageable with supportive treatment in two cats.</p><p><strong>Conclusions and relevance: </strong>In these cats, the decision to treat with chloramphenicol was made because an alternative oral antibiotic was not available to target the multidrug-resistant pathogens. Infections of the skin or urinary tract were common. Overall, chloramphenicol was well tolerated, and treatment success was possible for most cats.</p>","PeriodicalId":15851,"journal":{"name":"Journal of Feline Medicine and Surgery","volume":null,"pages":null},"PeriodicalIF":1.9,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142391008","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Clinical perioperative outcomes in 39 cats after single session bilateral femoral head and neck excision 单次双侧股骨头和股骨颈切除术后 39 只猫的临床围手术期结果
IF 1.7 2区 农林科学
Journal of Feline Medicine and Surgery Pub Date : 2024-09-17 DOI: 10.1177/1098612x241275890
Hania Brasali, Sam Stewart, Nicole S Amato
{"title":"Clinical perioperative outcomes in 39 cats after single session bilateral femoral head and neck excision","authors":"Hania Brasali, Sam Stewart, Nicole S Amato","doi":"10.1177/1098612x241275890","DOIUrl":"https://doi.org/10.1177/1098612x241275890","url":null,"abstract":"ObjectivesThe aim of the study was to evaluate the perioperative outcomes and complications of single session bilateral femoral head and neck excision (FHNE) in cats for treatment of bilateral coxofemoral joint disease.MethodsThe medical records of cats undergoing a single session bilateral FHNE were identified and the history, signalment, diagnosis, surgery reports, anesthetic records, postoperative radiographs, postoperative examinations, complications and outcomes were recorded.ResultsA total of 39 cats undergoing a single session bilateral FHNE were included. Bilateral slipped capital femoral epiphysis was the most commonly diagnosed etiology. All cats were discharged within 48 h of the procedure. One major complication and five minor complications were reported. All but one cat returned to normal activity and no owners reported concerns after the 2-week postoperative recheck.Conclusions and relevanceSingle session bilateral FHNE is a viable surgical option for the treatment of bilateral coxofemoral disease in cats that results in a quick return to function, especially when other options are not indicated, available or affordable.","PeriodicalId":15851,"journal":{"name":"Journal of Feline Medicine and Surgery","volume":null,"pages":null},"PeriodicalIF":1.7,"publicationDate":"2024-09-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142261420","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Histopathological changes in testicular lesions in cats 猫睾丸病变的组织病理学变化
IF 1.7 2区 农林科学
Journal of Feline Medicine and Surgery Pub Date : 2024-09-17 DOI: 10.1177/1098612x241264124
Fraser I Hill, May PY Tse, Steve W Mills, Jeanine R Sandy, Ibrahim Elsohaby, Vanessa R Barrs
{"title":"Histopathological changes in testicular lesions in cats","authors":"Fraser I Hill, May PY Tse, Steve W Mills, Jeanine R Sandy, Ibrahim Elsohaby, Vanessa R Barrs","doi":"10.1177/1098612x241264124","DOIUrl":"https://doi.org/10.1177/1098612x241264124","url":null,"abstract":"ObjectivesThe aim of this retrospective study was to describe the neoplastic and non-neoplastic lesions seen on histopathological examination of cat testes in Hong Kong between 2018 and 2024.MethodsA total of 26 single or dual testes samples were collected from 18 cats by veterinarians at 14 veterinary clinics and submitted for histopathological examination. Laboratory records, including signalment, lesion location, age, breed and histopathological findings, were reviewed for each cat.ResultsNeoplastic testicular lesions were seen in three older cats (median age 8.5 years; range 3–17) compared with 18 non-neoplastic lesions in 15 cats (median age 1 year; range 0.5–3). The most common non-neoplastic lesions included inflammation (in the testes, epididymis, tunics and ductus deferens), cryptorchidism, and one case each of polyorchidism and epididymal cyst formation. Two of the testes with inflammation were identified on immunohistochemical staining as feline coronavirus-infected and one pair of testes was associated with the presence of extracellular Gram-negative bacteria at the lesion site. Three different neoplastic lesions were identified, one each of Sertoli cell tumour, leiomyoma and fibrosarcoma.Conclusions and relevanceNon-neoplastic testicular lesions were most common, including inflammation, cryptorchidism, polyorchidism and epididymal cysts. To our knowledge, leiomyoma and fibrosarcoma have not been reported in cat testes before and represent important differential diagnoses for testicular lesions.","PeriodicalId":15851,"journal":{"name":"Journal of Feline Medicine and Surgery","volume":null,"pages":null},"PeriodicalIF":1.7,"publicationDate":"2024-09-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142261419","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Signalment and laboratory findings in cats with diabetes mellitus in Germany: a retrospective review of laboratory submissions of 129,505 cats 德国猫糖尿病患者的信号和实验室检查结果:对 129 505 只猫的实验室报告的回顾性分析
IF 1.7 2区 农林科学
Journal of Feline Medicine and Surgery Pub Date : 2024-09-17 DOI: 10.1177/1098612x241262669
Bente Guse, Judith Langenstein, Natali Bauer, Katarina Hazuchova
{"title":"Signalment and laboratory findings in cats with diabetes mellitus in Germany: a retrospective review of laboratory submissions of 129,505 cats","authors":"Bente Guse, Judith Langenstein, Natali Bauer, Katarina Hazuchova","doi":"10.1177/1098612x241262669","DOIUrl":"https://doi.org/10.1177/1098612x241262669","url":null,"abstract":"ObjectivesThe aims of this study were to compare signalment and laboratory parameters between diabetic (D) and non-diabetic (ND) cats and poorly-controlled diabetic (PD) and well-controlled diabetic (WD) cats in Germany.MethodsLaboratory data from Antech Lab Germany between 2015 and 2018 were retrospectively analysed. Age, sex, red blood cell count (RBC), creatinine (CREA), alkaline phosphatase (AP), alanine aminotransferase (ALT), bilirubin (BILI), cholesterol (CHOL), triglycerides (TRI), glucose (GLU) and total thyroxine (TT4) were compared between D (fructosamine ⩾340 µmol/l) and ND cats, and PD (fructosamine &gt;500 µmol/l) and WD (fructosamine 340–500 µmol/l) cats. The proportion of cats with anaemia (RBC ⩽4.21 ×10<jats:sup>12</jats:sup>/l), CREA &gt;250 µmol/l, ALT &gt;455 U/l, AP &gt;315 U/l, BILI ⩾35 µmol/l and TT4 &gt; reference interval (RI) was compared between PD and WD cats. Data are presented as median and interquartile range (IQR) and analysed using non-parametric tests. Significance was P&lt;0.05, and effect size was assessed by Cramér V or r.ResultsIn total, 129,505 cats were included (D: n = 9334 [prevalence 7.2%], WD: n = 5670/9334 [60.7%]). The median age of D and ND cats was 12 years (IQR D 9–14; ND 9–15); there was no difference in sex. A significant difference was found between groups (D vs ND; PD vs WD) for all parameters studied. Considering the effect sizes and medians outside the RI, the only relevant difference was higher CHOL, TRI, AP and GLU in PD compared with WD (CHOL: PD 7.46 [5.85–9.32] vs WD 5.44 [4.32–6.97] mmol/l, P&lt;0.001, r = 0.39; TRI: PD 1.44 [0.84–3.66] vs WD 0.78 [0.5–1.35] mmol/l, P &lt;0.001, r = 0.35; AP: PD 66 [47–92] vs WD 35 [23–59] U/l, P &lt;0.001, r = 0.39; GLU: PD 23.7 [20.15–27.3] vs WD 6.89 [5–11.31] mmol/l, P &lt;0.001, r = 0.69).Conclusions and relevanceLaboratory changes in diabetic cats were mild and mainly associated with lipid derangements.","PeriodicalId":15851,"journal":{"name":"Journal of Feline Medicine and Surgery","volume":null,"pages":null},"PeriodicalIF":1.7,"publicationDate":"2024-09-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142261415","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Video-based compilation of acute pain behaviours in cats 猫咪急性疼痛行为视频汇编
IF 1.7 2区 农林科学
Journal of Feline Medicine and Surgery Pub Date : 2024-09-17 DOI: 10.1177/1098612x241260712
Sabrine Marangoni, Paulo V Steagall
{"title":"Video-based compilation of acute pain behaviours in cats","authors":"Sabrine Marangoni, Paulo V Steagall","doi":"10.1177/1098612x241260712","DOIUrl":"https://doi.org/10.1177/1098612x241260712","url":null,"abstract":"ObjectivesThe aim of this work was to create a video-based compilation of acute pain behaviours in cats as an open-access online resource for training of veterinary health professionals.MethodsA database comprising 60 h of video recordings of cats was used. Videos were previously recorded after ethical approval and written client consent forms, and involved cats with different types (eg, medical, surgical, trauma, orofacial) and degrees (eg, from no pain to severe pain) of acute pain, before and after surgery or the administration of analgesia. The database included videos of cats of different coat colours, ages, sex and breeds. Video selection was based on a published ethogram of acute pain behaviours in cats. Videos were selected by one observer (SM) according to their definition and quality, followed by a second round of screening by two observers (SM and PVS). Video editing included a standardised template (ie, watermark and titles).ResultsA total of 24 videos (mean length 33 ± 17 s) with each acute pain-related behaviour described in the ethogram were uploaded to an open-access online video-sharing platform ( http://www.youtube.com/@Steagalllaboratory ) with an individual hyperlink. Videos were provided with a short description of the behaviour for the public.Conclusions and relevanceThis video-based compilation may promote better training of veterinary health professionals on acute pain assessment while improving feline health and welfare and the understanding of cat behaviours.","PeriodicalId":15851,"journal":{"name":"Journal of Feline Medicine and Surgery","volume":null,"pages":null},"PeriodicalIF":1.7,"publicationDate":"2024-09-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142261417","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Tensile testing in feline ventral abdominal coeliotomy closure with different sizes of polydioxanone suture material: a biomechanical study 使用不同尺寸的聚二氧杂蒽酮缝合材料进行猫腹部开腹缝合的拉力测试:一项生物力学研究
IF 1.7 2区 农林科学
Journal of Feline Medicine and Surgery Pub Date : 2024-09-17 DOI: 10.1177/1098612x241271871
Sebastian Jaenich, Tomasz Bartkowiak, Hubert Jopek, Mathias Brunnberg, Pavel Slunsky
{"title":"Tensile testing in feline ventral abdominal coeliotomy closure with different sizes of polydioxanone suture material: a biomechanical study","authors":"Sebastian Jaenich, Tomasz Bartkowiak, Hubert Jopek, Mathias Brunnberg, Pavel Slunsky","doi":"10.1177/1098612x241271871","DOIUrl":"https://doi.org/10.1177/1098612x241271871","url":null,"abstract":"ObjectivesThe aim of this study was to evaluate, in vitro, the load and type of failure of the sutured ventral abdominal fascia of cats with different sizes of suture material made of polydioxanone (PDX) (2-0, 3-0, 4-0, 5-0 USP).MethodsA total of 32 samples of the ventral abdominal wall from 16 cadaveric cats were harvested using an hourglass-shaped template. The samples were sectioned longitudinally along the linea alba and then sutured together in a continuous pattern using four different randomly assigned sizes of pdx suture material (2-0, 3-0, 4-0, 5-0 USP). A universal testing machine was used for linear distraction of the samples. The tensile strength and type of failure were recorded and analysed. Three types of failure were defined: suture material failure (S), suture line failure (T1) and failure of the abdominal wall further away from the linea alba (T2).ResultsThe frequency of suture material failure decreased with increasing suture size. Suture size 5-0 failed due to a S failure in 6/8 samples, PDX 4-0 failed in 2/8 samples and PDX 3-0 failed in only 1/8 samples. However, PDX 2-0 failed due to only T1 or T2 failures, with both failures being almost equally represented. No statistically significant differences in the load to failure between PDX 2-0, 3-0 and 4-0 were noted ( P &gt;0.05). The risk of suture failure increased with decreasing suture size diameter.Conclusions and relevancePDX 2-0 and 3-0 can be used without reservation for the closure of ventral midline coeliotomy in cats. Although there was no statistically significant difference between PDX 2-0, 3-0 and 4-0, PDX 4-0 showed a higher probability for suture breakage and should be used only after careful consideration of the patient while clinical evaluation is pending. Pdx 5-0 cannot be recommended as a safe suture size for this type of surgical closure.","PeriodicalId":15851,"journal":{"name":"Journal of Feline Medicine and Surgery","volume":null,"pages":null},"PeriodicalIF":1.7,"publicationDate":"2024-09-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142261416","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The incidence and trends of proteinuria, azotemia and hypertension in cats receiving toceranib phosphate 接受磷酸托塞瑞尼治疗的猫咪蛋白尿、氮质血症和高血压的发生率及趋势
IF 1.7 2区 农林科学
Journal of Feline Medicine and Surgery Pub Date : 2024-09-17 DOI: 10.1177/1098612x241266418
Kimberly Williams, Valerie MacDonald-Dickinson, Arata Matsuyama
{"title":"The incidence and trends of proteinuria, azotemia and hypertension in cats receiving toceranib phosphate","authors":"Kimberly Williams, Valerie MacDonald-Dickinson, Arata Matsuyama","doi":"10.1177/1098612x241266418","DOIUrl":"https://doi.org/10.1177/1098612x241266418","url":null,"abstract":"ObjectivesThis retrospective study aimed to determine the incidence and trends of proteinuria, elevations in serum creatinine and urea, and systolic blood pressure in cats undergoing treatment with toceranib.MethodsIn total, 32 cats treated with toceranib for malignancies were analyzed. Cats were included if urinalysis and urine protein:creatinine ratio (UPC) measurements were available at 28 days (T1) and 56 days (T2) after starting the treatment. Cats with concurrent lower urinary tract disease, including urinary tract malignancy, were excluded. Friedman’s ANOVA compared variables between time points, and the Spearman test assessed the correlation between treatment duration and UPC.ResultsThe median starting dose of toceranib was 2.68 mg/kg (range 1.7–3.9). In total, 15 (46.9%) cats received concurrent non-steroidal anti-inflammatory drugs. The most commonly treated tumors were oral squamous cell carcinoma (n = 10) and mast cell tumor (n = 5). None of the 32 cats developed progressive proteinuria or azotemia during the follow-up period (median 56 days; range 56–336). Notably, UPC and serum creatinine were significantly lower at T2 compared with baseline ( P = 0.012 and 0.001, respectively). Among the four cats with baseline proteinuria, UPC decreased over time with or without concurrent telmisartan treatment (n = 2). All four of these cats experienced a reduction in tumor size with toceranib concurrently with their decreased UPC. There was no significant correlation between UPC and the duration of toceranib treatment ( P = 0.089). Blood pressure was not significantly different over the assessed time points.Conclusions and relevanceThe incidence of proteinuria, renal azotemia and hypertension in cats treated with toceranib for neoplasia appears to be low. Toceranib may be a viable treatment option even in cats with pre-existing proteinuria or renal disease, with careful monitoring of trends recommended.","PeriodicalId":15851,"journal":{"name":"Journal of Feline Medicine and Surgery","volume":null,"pages":null},"PeriodicalIF":1.7,"publicationDate":"2024-09-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142261418","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Feline friendly POCUS: how to implement it into your daily practice 猫科动物友好型 POCUS:如何将其应用到日常实践中
IF 1.7 2区 农林科学
Journal of Feline Medicine and Surgery Pub Date : 2024-09-10 DOI: 10.1177/1098612x241276916
Hugo Swanstein, Søren Boysen, Laura Cole
{"title":"Feline friendly POCUS: how to implement it into your daily practice","authors":"Hugo Swanstein, Søren Boysen, Laura Cole","doi":"10.1177/1098612x241276916","DOIUrl":"https://doi.org/10.1177/1098612x241276916","url":null,"abstract":"Practical relevance:Cats are great pretenders; they often hide illness until they are critical. This makes patients of this species challenging to assess and manage in the emergency setting where quick and stress-free diagnosis and treatment are necessary. Veterinary point-of-care ultrasound (POCUS) is a rapid, evidence-based, non-invasive, repeatable, cage-side ultrasonographic examination designed to answer clinically driven questions without compromising feline wellbeing. Integrating feline friendly POCUS as an extension of the physical examination to streamline diagnostic and therapeutic interventions, thereby limiting stress and improving overall patient care, is advocated by the authors of this article.Equipment:Given the multitude of ultrasound machines and probes available that are portable, meaning they can be moved around the clinic and used patient-side, it should be possible for most practitioners to integrate POCUS into daily practice. The authors’ preferred equipment for feline POCUS is a microconvex probe and a portable machine with a fixed pre-set. This set-up allows the clinician to complete all POCUS (abdominal, lung and pleural space, and heart) without needing to move the patient, change probes or restrain the patient in a particular position, ultimately saving time, personnel and cost while maintaining patient comfort and safety.Aim:This review aims to serve as a valuable resource for veterinarians seeking to improve their feline patient care through the judicious utilisation of POCUS. In this article, the complex challenges posed by cats are addressed, and the different POCUS techniques, applications and clinical recommendations are discussed.Evidence base:This review draws on the published literature, as well as the authors’ own collective experience when providing recommendations.","PeriodicalId":15851,"journal":{"name":"Journal of Feline Medicine and Surgery","volume":null,"pages":null},"PeriodicalIF":1.7,"publicationDate":"2024-09-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142213236","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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