Journal of Feline Medicine and Surgery最新文献

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2024 ISFM and AAFP consensus guidelines on the long-term use of NSAIDs in cats 2024 ISFM 和 AAFP 关于猫长期使用非甾体抗炎药的共识指南
IF 1.7 2区 农林科学
Journal of Feline Medicine and Surgery Pub Date : 2024-04-08 DOI: 10.1177/1098612x241241951
Samantha Taylor, Margaret Gruen, Kate KuKanich, B Duncan X Lascelles, Beatriz P Monteiro, Llibertat Real Sampietro, Sheilah Robertson, Paulo V Steagall
{"title":"2024 ISFM and AAFP consensus guidelines on the long-term use of NSAIDs in cats","authors":"Samantha Taylor, Margaret Gruen, Kate KuKanich, B Duncan X Lascelles, Beatriz P Monteiro, Llibertat Real Sampietro, Sheilah Robertson, Paulo V Steagall","doi":"10.1177/1098612x241241951","DOIUrl":"https://doi.org/10.1177/1098612x241241951","url":null,"abstract":"Practical relevance:Non-steroidal anti-inflammatory drugs (NSAIDs) are widely used and are effective for the management of pain in cats. These Guidelines will support veterinarians in decision-making around prescribing NSAIDs in situations of chronic pain, to minimise adverse effects and optimise pain management. Information is provided on mechanism of action, indications for use, screening prior to prescription, use in the presence of comorbidities, monitoring of efficacy, and avoidance and management of adverse effects.Clinical challenges:The cat's unique metabolism should be considered when prescribing any medications, including NSAIDs. Chronic pain may be challenging to detect in this species and comorbidities, particularly chronic kidney disease, are common in senior cats. Management of chronic pain may be complicated by prescription of other drugs with the potential for interactions with NSAIDs.Evidence base:These Guidelines have been created by a panel of experts brought together by the International Society of Feline Medicine (ISFM) and American Association of Feline Practitioners (AAFP). Information is based on the available literature, expert opinion and the panel members' experience.","PeriodicalId":15851,"journal":{"name":"Journal of Feline Medicine and Surgery","volume":"74 1","pages":""},"PeriodicalIF":1.7,"publicationDate":"2024-04-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140564649","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Thank you to our reviewers 感谢我们的评论员
IF 1.7 2区 农林科学
Journal of Feline Medicine and Surgery Pub Date : 2024-03-15 DOI: 10.1177/1098612x241238120
{"title":"Thank you to our reviewers","authors":"","doi":"10.1177/1098612x241238120","DOIUrl":"https://doi.org/10.1177/1098612x241238120","url":null,"abstract":"","PeriodicalId":15851,"journal":{"name":"Journal of Feline Medicine and Surgery","volume":"37 1","pages":""},"PeriodicalIF":1.7,"publicationDate":"2024-03-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140149098","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Bicavitary effusion in cats: retrospective analysis of signalment, clinical investigations, diagnosis and outcome. 猫双腔积液:信号、临床检查、诊断和结果的回顾性分析。
IF 1.7 2区 农林科学
Journal of Feline Medicine and Surgery Pub Date : 2024-03-01 DOI: 10.1177/1098612X241227122
Joshua J Hardwick, Christopher S F K Ioannides-Hoey, Natalie Finch, Victoria Black
{"title":"Bicavitary effusion in cats: retrospective analysis of signalment, clinical investigations, diagnosis and outcome.","authors":"Joshua J Hardwick, Christopher S F K Ioannides-Hoey, Natalie Finch, Victoria Black","doi":"10.1177/1098612X241227122","DOIUrl":"10.1177/1098612X241227122","url":null,"abstract":"<p><strong>Objectives: </strong>The aim of this study was to describe the clinical and diagnostic findings and outcome of cats with bicavitary effusion presenting to a referral centre.</p><p><strong>Methods: </strong>Medical records of cats presenting with bicavitary effusion were identified and their history, physical examination findings, clinicopathological data, diagnostic imaging findings, aetiology of bicavitary effusions (cardiac disease, neoplasia, infectious disease, sterile inflammatory disease, severe hypoalbuminaemia, trauma, coagulopathy or 'open' if no definitive diagnosis was reached) and outcome were recorded. Cox regression analysis was performed to identify independent predictors of death in cats with bicavitary effusion. Kaplan-Meier curves were generated for survival analysis.</p><p><strong>Results: </strong>In total, 103 cats with bicavitary effusion were included. Neoplasia and cardiac disease were the most common aetiologies of bicavitary effusion, in 21 (20.4%) and 20 (19.4%) cats, respectively, followed by infectious disease (n = 11, 10.7%), trauma (n = 13, 12.6%), hypoalbuminaemia (n = 6, 5.8%), sterile inflammatory disease (n = 4, 3.9%) and coagulopathy (n = 1, 1.0%). The median survival time for all cats with bicavitary effusion was 3 days. Cats with a neoplastic aetiology had a 2.03 times greater risk of death compared with cats in which no diagnosis was achieved. Neoplasia (<i>P</i> = 0.030) and pedigree breed status (<i>P</i> = 0.016) were independent predictors of death in the multivariable Cox regression model.</p><p><strong>Conclusions and relevance: </strong>This study highlights that bicavitary effusions in cats generally carry a guarded to poor prognosis, particularly if neoplasia is the underlying aetiology or if the cat is a pedigree breed. Cardiac disease appeared to be associated with a better prognosis, suggesting that assessment for congestive heart failure should be considered early when evaluating cats with bicavitary effusion. The prognosis for cats with feline infectious peritonitis is likely to be markedly improved by the advent of novel antiviral drugs, compared with the historical cohort of cats presented here.</p>","PeriodicalId":15851,"journal":{"name":"Journal of Feline Medicine and Surgery","volume":"26 3","pages":"1098612X241227122"},"PeriodicalIF":1.7,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10983610/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140175028","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Comparison of analgesic efficacy of tramadol, morphine and methadone in cats undergoing ovariohysterectomy. 比较曲马多、吗啡和美沙酮对接受卵巢切除术的猫的镇痛效果。
IF 1.7 2区 农林科学
Journal of Feline Medicine and Surgery Pub Date : 2024-03-01 DOI: 10.1177/1098612X231224662
Mariela Goich, Alejandra Bascuñán, Patricio Faúndez, Daniela Siel
{"title":"Comparison of analgesic efficacy of tramadol, morphine and methadone in cats undergoing ovariohysterectomy.","authors":"Mariela Goich, Alejandra Bascuñán, Patricio Faúndez, Daniela Siel","doi":"10.1177/1098612X231224662","DOIUrl":"10.1177/1098612X231224662","url":null,"abstract":"<p><strong>Objectives: </strong>The aim of this study was to compare the analgesic efficacy and the effect on physiological variables and behavior of the use of tramadol, methadone and morphine as preoperative analgesia in healthy cats undergoing elective ovariohysterectomy.</p><p><strong>Methods: </strong>Cats undergoing ovariohysterectomy were randomly assigned to receive one of the following premedication treatments intramuscularly: methadone (0.2 mg/kg; n = 10); morphine (0.2 mg/kg; n = 10); or tramadol (3 mg/kg; n = 10). Induction of anesthesia was done with propofol, and maintenance of anesthesia was done with isoflurane. Intraoperative heart rate, arterial blood pressure, respiratory rate, end-tidal isoflurane concentration and frequency of rescue analgesia (fentanyl 2.5 µg/kg) were compared between groups. Postoperative analgesia was assessed using the UNESP-Botucatu Multidimensional Composite Pain Scale, and perioperative serum glucose, cortisol concentrations and postoperative rescue analgesia were evaluated.</p><p><strong>Results: </strong>Intraoperative rescue analgesia was required in 76.5% of cats at some time during surgery, and 27% of cats required postoperative rescue analgesia up to 6 h after extubation. There were no significant differences between groups with respect to intraoperative and postoperative rescue analgesia, pain scale scores and end-tidal isoflurane concentrations. In the immediate postoperative period, after extubation, most of the patients presented with hypothermia; however, 1-6 h postoperatively, hyperthermia was observed in most of the patients, and was most common in the tramadol group.</p><p><strong>Conclusions and clinical relevance: </strong>Under the conditions of this study, methadone, morphine and tramadol produced satisfactory postoperative analgesia in most of the cats undergoing ovariohysterectomy, and the effects lasted up to 6 h postoperatively. Intraoperative analgesia was not sufficient in most cases. Significant cardiovascular or respiratory effects contraindicating the use of these drugs were not found. Postanesthetic hyperthermia occurred with all opioids studied and was more frequent in the tramadol group.</p>","PeriodicalId":15851,"journal":{"name":"Journal of Feline Medicine and Surgery","volume":"26 3","pages":"1098612X231224662"},"PeriodicalIF":1.7,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10983611/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140305849","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Comparison of Doppler ultrasonic sphygmomanometry, oscillometry and high-definition oscillometry for non-invasive blood pressure measurement in conscious cats. 多普勒超声血压计、示波法和高清示波法在清醒猫体内进行无创血压测量的比较。
IF 1.7 2区 农林科学
Journal of Feline Medicine and Surgery Pub Date : 2024-03-01 DOI: 10.1177/1098612X241231471
Marieke Knies, Erik Teske, Hans Kooistra
{"title":"Comparison of Doppler ultrasonic sphygmomanometry, oscillometry and high-definition oscillometry for non-invasive blood pressure measurement in conscious cats.","authors":"Marieke Knies, Erik Teske, Hans Kooistra","doi":"10.1177/1098612X241231471","DOIUrl":"10.1177/1098612X241231471","url":null,"abstract":"<p><strong>Objectives: </strong>Systemic arterial hypertension is a common occurrence and can have serious adverse consequences in cats. Therefore, measuring blood pressure is very important. There are many indirect blood pressure measurement devices available. This study compared Doppler, oscillometric (petMAP Graphic II, SunTech Vet20, the Cardell Insight-X0000) and high-definition oscillometry devices for the non-invasive measurement of blood pressure in conscious cats.</p><p><strong>Methods: </strong>In this prospective study, blood pressure was measured in 32 cats using the different devices according to the recommendations of the American College of Veterinary Internal Medicine Consensus Statement. Blood pressures (systolic blood pressure [SBP], diastolic blood pressure [DBP], mean arterial pressure [MAP]), time to complete measurements, number of attempts needed, coefficient of variation (CV) between the blood pressure measurements of the different devices, ease of completing measurements and apparent stress level of the cat were assessed.</p><p><strong>Results: </strong>There was a significant difference between devices in the time taken to obtain blood pressure readings and the number of attempts necessary to obtain six reliable measurements. The CV of the Doppler device was significantly smaller than that of the rest of the devices, but there were no other differences between the devices. The mean SBP, DBP and MAP measured by the petMAP device were significantly higher than the measurements from the other devices. The perceived ease of measurement was not significantly different between the various machines. The perceived level of stress of measurement with the Doppler device was significantly higher compared with the other devices but did not lead to an increased SBP.</p><p><strong>Conclusions and relevance: </strong>Using a Doppler device to measure blood pressure in conscious cats is fast, relatively easy and gives reliable results. A disadvantage is that the Doppler device can only measure SBP, while oscillometric devices also provide DBP and MAP. However, in veterinary medicine, systolic hypertension is considered the most relevant.</p>","PeriodicalId":15851,"journal":{"name":"Journal of Feline Medicine and Surgery","volume":"26 3","pages":"1098612X241231471"},"PeriodicalIF":1.7,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10983607/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140305850","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Identifying policy alternatives to enable the virtual establishment of a veterinarian-client-patient relationship. 确定政策备选方案,以便虚拟建立兽医-客户-患者关系。
IF 1.7 2区 农林科学
Journal of Feline Medicine and Surgery Pub Date : 2024-03-01 DOI: 10.1177/1098612X231224167
Sue M Neal, Mike J Greenberg
{"title":"Identifying policy alternatives to enable the virtual establishment of a veterinarian-client-patient relationship.","authors":"Sue M Neal, Mike J Greenberg","doi":"10.1177/1098612X231224167","DOIUrl":"10.1177/1098612X231224167","url":null,"abstract":"<p><strong>Objectives: </strong>This research seeks to identify an existing policy stream around the establishment of a veterinarian-client-patient relationship (VCPR) through telemedicine to provide evidence of, and advance policy alternatives for, states and countries looking to allow this practice responsibly. This is seen as an important step for access to veterinary care, particularly for cats.</p><p><strong>Methods: </strong>The multiple streams policy framework requires identification of a centering event, problem stream, policy stream and politics stream in order to have the necessary conditions for policy change to occur. This research identifies that policy stream through thematic content analysis. State-level policies from across the entire USA that address the virtual establishment of a physician-patient relationship were analyzed to provide themes that could be applied to similar policies in veterinary medicine.</p><p><strong>Results: </strong>Ten key themes were identified and further organized into four high-order concepts through the thematic content analysis. Detailed accounting of the specific policy alternatives is provided in the supplementary materials.</p><p><strong>Conclusions and relevance: </strong>The themes and concepts presented provide evidence of a robust policy stream. This content analysis, and the supporting supplementary details, provide many options to guide states in the development of sound policies for the virtual establishment of a VCPR by drawing from the more matured field of human medicine.</p>","PeriodicalId":15851,"journal":{"name":"Journal of Feline Medicine and Surgery","volume":"26 3","pages":"1098612X231224167"},"PeriodicalIF":1.7,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10983609/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140119694","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Evaluation of the analgesic efficacy of grapiprant compared with robenacoxib in cats undergoing elective ovariohysterectomy in a prospective, randomized, masked, non-inferiority clinical trial. 在一项前瞻性、随机、掩蔽、非劣效性临床试验中,评估格拉吡特与罗苯昔布对接受择期卵巢切除术的猫的镇痛效果。
IF 1.7 2区 农林科学
Journal of Feline Medicine and Surgery Pub Date : 2024-03-01 DOI: 10.1177/1098612X241230941
Elizabeth K Pisack, Stephanie A Kleine, Chiara E Hampton, Christopher K Smith, Jennifer Weisent, Rebecca DeBolt, Cambrie Schumacher, Genevieve Bussières, Reza Seddighi
{"title":"Evaluation of the analgesic efficacy of grapiprant compared with robenacoxib in cats undergoing elective ovariohysterectomy in a prospective, randomized, masked, non-inferiority clinical trial.","authors":"Elizabeth K Pisack, Stephanie A Kleine, Chiara E Hampton, Christopher K Smith, Jennifer Weisent, Rebecca DeBolt, Cambrie Schumacher, Genevieve Bussières, Reza Seddighi","doi":"10.1177/1098612X241230941","DOIUrl":"10.1177/1098612X241230941","url":null,"abstract":"<p><strong>Objectives: </strong>The main objective of this study was to compare the postoperative analgesic effects of grapiprant with those of robenacoxib in cats undergoing ovariohysterectomy (OVH).</p><p><strong>Methods: </strong>In total, 37 female cats (age range 4 months-10 years, weighing ⩾2.5 kg) were enrolled in a prospective, randomized, masked, non-inferiority (NI) clinical trial. Cats received oral robenacoxib (1 mg/kg) or grapiprant (2 mg/kg) 2 h before OVH. Analgesia was assessed via the Feline Grimace Scale (FGS), the Glasgow Composite Measure Pain Scale-Feline (CMPS-F), von Frey monofilaments (vFFs) and pressure algometry (ALG) 2 h before treatment administration, at extubation, and 2, 4, 6, 8, 18 and 24 hours after extubation. Hydromorphone (<8 h postoperatively) or buprenorphine (>18 h postoperatively) were administered to cats with scores of ⩾5/20 on CMPS-F and/or ⩾4/10 on FGS. NI margins for CMPS-F and vFFs were set at 3 and -0.2, respectively. A mixed-effect ANOVA was used for FGS scores (<i>P</i> <0.05). Data are reported as mean ± SEM.</p><p><strong>Results: </strong>The data from 33 cats were analyzed. The upper limit of the 95% confidence interval (CI) (0.35) was less than the NI margin of 3 for CMPS-F, and the lower limit of the 95% CI (0.055) was greater than the NI margin of -0.2 for vFFs, indicating NI of grapiprant. The FGS scores were greater than baseline at extubation for both treatments (1.65 ± 0.63; <i>P</i> = 0.001); however, there was no difference between treatments. There was no difference between treatments, nor treatment by time interaction, for vFFs (<i>P</i> <0.001). The CMPS-F scores for both treatments were higher at extubation but returned to baseline after 4 h (<i>P</i> <0.001). For ALG, there was no difference in treatment or treatment by time interaction. The robenacoxib group had lower pressure readings at extubation and 6 h compared with baseline.</p><p><strong>Conclusions and relevance: </strong>These results indicate that grapiprant was non-inferior to robenacoxib for mitigating postsurgical pain in cats after OVH performed via ventral celiotomy. The impact of grapiprant for analgesia in OVH via the flank is unknown.</p>","PeriodicalId":15851,"journal":{"name":"Journal of Feline Medicine and Surgery","volume":"26 3","pages":"1098612X241230941"},"PeriodicalIF":1.7,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10983605/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140175029","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Impact of stress on the tear production of healthy cats. 压力对健康猫咪泪液分泌的影响。
IF 1.7 2区 农林科学
Journal of Feline Medicine and Surgery Pub Date : 2024-03-01 DOI: 10.1177/1098612X241233116
Larissa Donat Almagro, Izabelle Moutinho, Victor Mendes de Oliveira, Gentil Ferreira Gonçalves
{"title":"Impact of stress on the tear production of healthy cats.","authors":"Larissa Donat Almagro, Izabelle Moutinho, Victor Mendes de Oliveira, Gentil Ferreira Gonçalves","doi":"10.1177/1098612X241233116","DOIUrl":"10.1177/1098612X241233116","url":null,"abstract":"<p><strong>Objectives: </strong>This study aimed to determine the impact of acute stress on tear production in companion cats to provide a basis for minimizing stress-inducing stimuli during ophthalmic evaluations.</p><p><strong>Methods: </strong>A total of 24 healthy owned cats (12 males, 12 females) of mixed breed, aged 8 months to 7 years, with no history of ocular diseases, were selected for the study. The cats were housed in individual cages under controlled conditions for 6 days. The Schirmer tear test-1 (STT-1) was performed in the morning (between 9:00 am and 11:00 am) using test strips from the same batch. The first test (without stress) was conducted on the fifth day of acclimation, and the second test (with stress) on the sixth day. The stress stimulus consisted of recordings of barking dogs, cats fighting and the murmuring of people. For both tests, the heart rate was assessed with a stethoscope before, during and after the tests, and the environmental stress level was also evaluated. Results are presented as mean ± SD and 95% confidence interval (CI).</p><p><strong>Results: </strong>The study found that STT-1 values were significantly higher (<i>P</i> = 0.009) with stress (22.2 ± 6.0 mm/min [95% CI 19.9-24.6]) than without stress (17.5 ± 6.9 mm/min [95% CI 14.8-20.2]). Similarly, the heart rate was significantly higher (<i>P</i> = 0.028) in stress vs non-stress conditions (213.4 ± 37.5 beats per minute [bpm] [95% CI 198.7-228.1] vs 171.5 ± 28.6 bpm [95% CI 160.3-182.7], respectively), and the environmental stress score was significantly higher (<i>P</i> <0.001) in stress vs non-stress conditions (3.3 ± 0.5 [95% CI 3.1-3.5] vs 1.2 ± 0.4 [95% CI 1.1-1.4], respectively).</p><p><strong>Conclusions and relevance: </strong>Stress increased tear production in cats. Although the mean STT-1 value obtained under stress conditions was within the normal range, stress can influence the test results. The use of cat friendly handling techniques facilitates execution of the STT-1.</p>","PeriodicalId":15851,"journal":{"name":"Journal of Feline Medicine and Surgery","volume":"26 3","pages":"1098612X241233116"},"PeriodicalIF":1.7,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10983608/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140305851","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Anti-rabies humoral immune response in cats after concurrent vs separate vaccination against rabies and feline leukaemia virus using canarypox-vectored vaccines. 使用金丝雀痘病毒疫苗同时接种狂犬病和猫白血病病毒疫苗与单独接种疫苗后猫的抗狂犬病体液免疫反应。
IF 1.7 2区 农林科学
Journal of Feline Medicine and Surgery Pub Date : 2024-02-01 DOI: 10.1177/1098612X231218643
Anna-Karina Weidinger, Michèle Bergmann, Matthias König, Yury Zablotski, Katrin Hartmann
{"title":"Anti-rabies humoral immune response in cats after concurrent vs separate vaccination against rabies and feline leukaemia virus using canarypox-vectored vaccines.","authors":"Anna-Karina Weidinger, Michèle Bergmann, Matthias König, Yury Zablotski, Katrin Hartmann","doi":"10.1177/1098612X231218643","DOIUrl":"10.1177/1098612X231218643","url":null,"abstract":"<p><strong>Objectives: </strong>Some expert groups recommend that cats should be vaccinated with non-adjuvanted feline leukaemia virus (FeLV) and rabies vector vaccines, which, in the European Union, are currently not licensed for concurrent use and have to be administered at least 14 days apart (different from the USA) and thus at separate visits, which is associated with more stress for cats and owners. The aim of this study was to assess the anti-rabies antibody response in cats after vaccination against rabies and FeLV at concurrent vs separate (4 weeks apart) visits using two canarypox-vectored vaccines (Purevax Rabies and Purevax FeLV; Boehringer Ingelheim) and to evaluate the occurrence of vaccine-associated adverse events (VAAEs).</p><p><strong>Methods: </strong>Healthy FeLV antigen-negative client-owned kittens (n = 106) were prospectively included in this randomised study. All kittens received primary vaccinations against rabies (week 0) and FeLV (weeks 4 and 8). After 1 year, the study group (n = 52) received booster vaccinations against rabies and FeLV concurrently at the same visit (weeks 50-52). The control group (n = 54) received booster vaccinations against rabies (weeks 50-52) and FeLV (weeks 54-56) separately. Anti-rabies virus antibodies (anti-RAV Ab) were determined by fluorescent antibody virus neutralisation assay at weeks 4, 50-52 and 54-56, and compared between both groups using a Mann-Whitney U-test.</p><p><strong>Results: </strong>Four weeks after the first rabies vaccination, 87/106 (82.1%) kittens had a titre ⩾0.5 IU/ml and 19/106 (17.9%) had a titre <0.5 IU/ml. Four weeks after the 1-year rabies booster, all cats had adequate anti-RAV Ab according to the World Organisation for Animal Health (⩾0.5 IU/ml), and the titres of the study group (median = 14.30 IU/ml) and the control group (median = 21.39 IU/ml) did not differ significantly (<i>P</i> = 0.141). VAAEs were observed in 7/106 (6.6%) cats.</p><p><strong>Conclusions and relevance: </strong>Concurrent administration of Purevax FeLV and Purevax Rabies vector vaccines at the 1-year booster does not interfere with the development of anti-RAV Ab or cause more adverse effects and thus represents a better option than separate vaccination visits for cats and owners.</p>","PeriodicalId":15851,"journal":{"name":"Journal of Feline Medicine and Surgery","volume":"26 2","pages":"1098612X231218643"},"PeriodicalIF":1.7,"publicationDate":"2024-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10911302/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139735408","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
2024 AAFP indoor/outdoor lifestyle position statement. 2024 全美全科医生协会室内/室外生活方式立场声明。
IF 1.7 2区 农林科学
Journal of Feline Medicine and Surgery Pub Date : 2024-02-01 DOI: 10.1177/1098612X241227827
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