L. Ke, Zong-Keng Kuo, Yu-Shih Chen, Hsiang-Wen Tseng, Cheng-Hsien Liu
{"title":"PEGDA-based photocrosslinking platform for real time cell trapping","authors":"L. Ke, Zong-Keng Kuo, Yu-Shih Chen, Hsiang-Wen Tseng, Cheng-Hsien Liu","doi":"10.1109/NEMS.2012.6196748","DOIUrl":"https://doi.org/10.1109/NEMS.2012.6196748","url":null,"abstract":"Poly (ethylene glycol)-diacrylate (PEG-DA) is a commonly used material in tissue engineering. It is cross-linking via UV-initiated photopolymerization to form the PEG-DA microstructures. This paper reports the fabrication of capillary PEG-DA architectures on photopolymerizable hydrogel characteristic. In the UV-initiated photopolymerization, oxygen can damage the photopolymerization reaction that to from microinterstices. In PDMS-based chip, a little oxygen in PDMS material is stored in PEG-DA material. By the way, we designed PEGDA-based V-shape microbarriers to trapped HMEC-1 cell for another biotechnology. For V-shaped microbarriers, we used the solution of the PEG-DA had been exposed to form V-shaped barriers by mask pattern. Cell trapping array platform was used for understanding fundamental cell studies which are cell-cell interactions and cell responses, such as hydrodynamic trapping system.","PeriodicalId":156839,"journal":{"name":"2012 7th IEEE International Conference on Nano/Micro Engineered and Molecular Systems (NEMS)","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2012-03-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133598314","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"On the design of subwavelength waveguiding structures for terahertz Applications","authors":"Vikas Singal, S. Smaili, Y. Massoud","doi":"10.1109/NEMS.2012.6196827","DOIUrl":"https://doi.org/10.1109/NEMS.2012.6196827","url":null,"abstract":"Closing the THz gap would lead to a tremendous of advancement in a wide range of applications such as biomedical imaging, security, and material inspection. The gap refers to the lack of devices for the manipulation of THz radiation as compared to its microwave and optical counterparts. Plasmonic devices based on semiconductors rather than metals allow the realization of efficient and small scale THz devices by utilizing the unique properties of plasmon oscillations. In this paper, we investigate the performance of an InSb-SiO2-InSb structure for THz waveguiding. We study the propagation length and the skin depth of the symmetric and antisymmetric transverse magnetic modes of these waveguides. We use numerical techniques to solve for the dispersion relation and derive the propagation length and the skin depth as a function of frequency.","PeriodicalId":156839,"journal":{"name":"2012 7th IEEE International Conference on Nano/Micro Engineered and Molecular Systems (NEMS)","volume":"22 11","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2012-03-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114129286","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Nanofluidic device with self-assembled nafion membrane utilizing capillary valve","authors":"Shuo Wang, Huaiqiang Yu, Wei Wang, Zhihong Li","doi":"10.1109/NEMS.2012.6196861","DOIUrl":"https://doi.org/10.1109/NEMS.2012.6196861","url":null,"abstract":"In this paper, a PDMS-based nanofluidic device for ICP (ion concentration polarization) was designed, fabricated and tested. In this device, a Nafion membrane, which acted as a network of nanochannels and provided paths for particular ions to migrate between main channel and buffer channel, was formed in 20μm-wide microchannel using capillary valve structure. Ion concentration polarization effect was observed when a voltage of 80 volts was applied across the Nafion junction. The fabrication process was simple and inexpensive. The manipulation of cells movement was successfully demonstrated using our PDMS micro-chip.","PeriodicalId":156839,"journal":{"name":"2012 7th IEEE International Conference on Nano/Micro Engineered and Molecular Systems (NEMS)","volume":"170 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2012-03-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132157238","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
C. Shih, Wei-Chih Lin, Chao-Sung Lin, Yung-Ning Pan
{"title":"Surface-modified diamond embedded in nickel matrix composite for intrinsic polishing application","authors":"C. Shih, Wei-Chih Lin, Chao-Sung Lin, Yung-Ning Pan","doi":"10.1109/NEMS.2012.6196867","DOIUrl":"https://doi.org/10.1109/NEMS.2012.6196867","url":null,"abstract":"An approach for fabricating a diamond conditioner by using a micro patterning and nickel electroforming method is demonstrated to improve the material removal rate (MRR) and the diamond worn ratio. By compared with the currently commercial conditioner, our developed diamond conditioner performs approximate 35% of the MRR and 18% of diamond worn ratio. The contact surface between the diamond and the counterpart is increased by the well-controlled of the grit protrusion which is within the range of 1.36 micrometer. This protrusion control not only results in the MRR and frictional coefficient increase, but also the load force reduction on each diamond grit during a wearing test. Furthermore, a chemical treatment is utilized to functionalize the surface of the diamond grits for the adhesion enhancement which can eliminate the matrix defects at the interface between the grits and nickel matrix.","PeriodicalId":156839,"journal":{"name":"2012 7th IEEE International Conference on Nano/Micro Engineered and Molecular Systems (NEMS)","volume":"34 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2012-03-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128256776","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A study of tin oxide thin film gas sensors with high oxygen vacancies","authors":"Chen Lin, Dacheng Zhang, Xiaodi Liu","doi":"10.1109/NEMS.2012.6196870","DOIUrl":"https://doi.org/10.1109/NEMS.2012.6196870","url":null,"abstract":"In this paper, gas sensors employing nanoscale tin oxide films of high oxygen vacancies were successfully made and tested in order to determine which factors affected the gas sensitivity of them. Firstly electrothermal simulations were carried out to predict the steady-state temperature distributions of the tin oxide thin film and the overall gas sensor using ANSYS™. Then the composition of the tin oxide calcined twice in O2 was analyzed by X-ray photoelectron spectroscopy (XPS). The result of XPS showed that the tin oxide under this condition had high oxygen vacancies. Finally, the ethanol sensing and humidity sensing properties of the gas sensors at various operating voltages and calcined in different conditions were tested. The experimental results showed that high gas sensitivity of the gas sensors could be achieved by changing the internal and external factors.","PeriodicalId":156839,"journal":{"name":"2012 7th IEEE International Conference on Nano/Micro Engineered and Molecular Systems (NEMS)","volume":"10 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2012-03-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133064080","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"High speed enucleation of oocyte using magnetically actuated microrobot on a chip","authors":"M. Hagiwara, A. Ichikawa, T. Kawahara, F. Arai","doi":"10.1109/NEMS.2012.6196794","DOIUrl":"https://doi.org/10.1109/NEMS.2012.6196794","url":null,"abstract":"We have developed novel microfluidic chip for enucleation of oocytes by magnetically actuated microrobots. Si and Ni composite microrobot driven by permanent magnets was developed and used as high power, high speed and high accuracy microarm to transport, rotate and cut swine oocyte in a microfluidic chip. The novelties of developed microrobot are as follows. 1) The drive frequency capability of microrobot improved by 10 times comparing to previously developed microrobot. 2) Si-Ni composite microrobot has no risk of biocompatibility. 3) A force of order of millinewton can be outputted from permanent magnets. The microfluidic chip was specially designed by fluid analysis of FEM for stable supply of the oocytes to the MMT manipulation area from the inlet. The integration of this high speed microrobot and microfluidic chip enables high throughput enucleation process in a microfluidic chip.","PeriodicalId":156839,"journal":{"name":"2012 7th IEEE International Conference on Nano/Micro Engineered and Molecular Systems (NEMS)","volume":"19 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2012-03-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126042010","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A high heating efficiency two-beam microhotplate for catalytic gas sensors","authors":"Lei Xu, Tie Li, Xiuli Gao, Yuelin Wang","doi":"10.1109/NEMS.2012.6196724","DOIUrl":"https://doi.org/10.1109/NEMS.2012.6196724","url":null,"abstract":"This paper presents a suspended-membrane-type microhotplate with high heating efficiency for catalytic gas sensors. This microhotplate has only two supporting beams through which heat loss via conduction can be effectively reduced. By isolating heat in a rectangular active membrane, high heating efficiency can be achieved. Power per active area (PPAA) of the microhotplate is only about 30% in comparison with current microhotplates. Based on the two-beam microhotplate, a catalytic gas sensor was fabricated by sol-gel process introducing Pd-Pt as the catalytic material. Test results indicate that this catalytic gas is sensitive to methane with a high sensitivity. And the sensor output has a fairly linear relation to methane concentration.","PeriodicalId":156839,"journal":{"name":"2012 7th IEEE International Conference on Nano/Micro Engineered and Molecular Systems (NEMS)","volume":"35 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2012-03-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124779841","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
J. Xiong, Yingzhan Yan, Chang-ling Zou, F. Sun, S. Yan, C. Xue, Jun Liu, Wendong Zhang
{"title":"A stable frequency references platform based on packaged microsphere-taper coupling system","authors":"J. Xiong, Yingzhan Yan, Chang-ling Zou, F. Sun, S. Yan, C. Xue, Jun Liu, Wendong Zhang","doi":"10.1109/NEMS.2012.6196787","DOIUrl":"https://doi.org/10.1109/NEMS.2012.6196787","url":null,"abstract":"“Whispering gallery modes” (WGM) optical micro- and nano resonators are important category in nanophotonics researches. The ultra-high quality factor (Q) makes them promising ranging from sensors, filters to low threshold sources. In the above supplications, the frequency stability of the WGM is critical, which is determined by several factors. In this paper, using the microsphere resonator we construct a robust packaged microsphere-taper coupling system (MTCS) to stabilize the resonant WGMs. Furthermore, a stable frequency references platform based on the packaged microcavity unit is constructed. This stable frequency references platform can eliminate the noise of the WGM, and promote the microresonator researches.","PeriodicalId":156839,"journal":{"name":"2012 7th IEEE International Conference on Nano/Micro Engineered and Molecular Systems (NEMS)","volume":"4 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2012-03-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126128746","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Rapid thermal plasma deposition of transparent nanocrystalline ZnO thin films and the effects of annealing","authors":"K. Teh, J. Pedersen, Heather Esposito","doi":"10.1109/NEMS.2012.6196770","DOIUrl":"https://doi.org/10.1109/NEMS.2012.6196770","url":null,"abstract":"Conductive, undoped zinc oxide nanocrystalline thin film with predominant c-axis orientation is prepared on crystalline and amorphous substrates using a rapid, one-step ambient-pressure, thermal plasma chemical vapor deposition process. Nonporous and conformal zinc oxide films can be prepared at temperature as low as 160°C, with an average grain size of 25 nm. Scanning electron micrographs indicate a growth rate of 15~50 nm/min, depending on factor including source temperature, deposition temperature, and pressure. X-ray diffraction shows a predominant (002) grain orientation that is independent of the substrate's crystallinity. For films with thickness of 200 nm, the average electrical conductivity ranges from 60-910 S/m. The results demonstrate the potential of thermal plasma CVD for the rapid synthesis of conductive zinc oxide film at ambient condition.","PeriodicalId":156839,"journal":{"name":"2012 7th IEEE International Conference on Nano/Micro Engineered and Molecular Systems (NEMS)","volume":"100 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2012-03-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124110500","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Kuo-Wei Chang, Chia-Tung Lee, P. T. Harishchandra, Hung-Po Chen, Ting-Ru Yueh, S. Puttaswamy, S. Sivashankar, Cheng-Hsien Liu
{"title":"3D biomimetic chip integrated with microvascular system for studying the liver specific functions","authors":"Kuo-Wei Chang, Chia-Tung Lee, P. T. Harishchandra, Hung-Po Chen, Ting-Ru Yueh, S. Puttaswamy, S. Sivashankar, Cheng-Hsien Liu","doi":"10.1109/NEMS.2012.6196760","DOIUrl":"https://doi.org/10.1109/NEMS.2012.6196760","url":null,"abstract":"We describe the design and fabrication of 3D chip that enables the cell co-culture under continuous flow perfusion and repeated in situ observation by light microscopy. Thin polydimethylsiloxane (PDMS) membrane was etched to create an array of through-holes, and sandwiched between two PDMS channels to form an upper chamber and lower chamber. In the upper chamber hepatocytes (HepG2) and fibroblasts (3T3) were co-cultured to mimic the liver whereas in the lower structure endothelial cells (HMEC-1) were cultured to mimic the vascular system at the cellular scale for providing nutrients to the in vitro liver mimicked in the upper channel.","PeriodicalId":156839,"journal":{"name":"2012 7th IEEE International Conference on Nano/Micro Engineered and Molecular Systems (NEMS)","volume":"41 1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2012-03-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129181794","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}