Journal of diabetes & metabolism最新文献_第8页

Prevalence of diabetes type-2 and pulmonary tuberculosis in Filipinos and treatment outcomes: A surveillance study in eastern Saudi Arabia 菲律宾2型糖尿病和肺结核的患病率和治疗结果:沙特阿拉伯东部的一项监测研究

Journal of diabetes & metabolism Pub Date : 2018-01-04 DOI: 10.4172/2155-6156-c1-078

L. A. Chaudhry

引用次数: 0

Investigation of Metabolic and Circulatory Parameters That Predict Effects of Dapagliflozin, a Sodium-Glucose Cotransporter 2 Inhibitor, on Blood Glucose and Body Weight in a Retrospective, Multicenter Study 一项多中心回顾性研究:代谢和循环参数预测钠-葡萄糖共转运蛋白2抑制剂达格列净对血糖和体重的影响

Journal of diabetes & metabolism Pub Date : 2018-01-01 DOI: 10.4172/2155-6156.1000810

Tadachika Kudo, Ichiro Abe, Midori Minezaki, K. Sugimoto, Hideyuki Fujii, H. Ohishi, Midori Nakagawa, Saori Yano, S. Matsubayashi, Miho Fukudome, H. Ninomiya, H. Ishii, T. Kodera, Hisao Itô, Y. Maeda, Kunihisa Kobayashi

引用次数: 2

Major Complication Associated With Diabetes Mellitus Type II in Punjab and Khyber Paktunkhwa Population 旁遮普和开伯尔-普赫图赫瓦人口II型糖尿病的主要并发症

Journal of diabetes & metabolism Pub Date : 2018-01-01 DOI: 10.4172/2155-6156.1000809

S. Riaz, S. Naz, U. Kousar, Zilfiqar Malik, R. Bashir

{"title":"Major Complication Associated With Diabetes Mellitus Type II in Punjab and Khyber Paktunkhwa Population","authors":"S. Riaz, S. Naz, U. Kousar, Zilfiqar Malik, R. Bashir","doi":"10.4172/2155-6156.1000809","DOIUrl":"https://doi.org/10.4172/2155-6156.1000809","url":null,"abstract":"Type-II diabetes mellitus is a particularly heterogeneous and multifactorial metabolic disorder that is characterized by a combination of insulin insufficiency and insulin resistance. The prevalence of diabetes mellitus has risen exponentially over the last three decades, with resultant increase in morbidity and mortality mainly due to its complications. Data of 400 individuals affected with diabetes mellitus type II were collected from different hospitals of Lahore (Punjab) and Dera Ismail khan (KPK) during the year 2016-2017. Two hundred individual data recruited from Punjab out of them 90 (45%) were male; while from KPK 107 (53.5%) were male. The age of these patients were range between 17 to 90 years but most of the patients fall in the range between 40-60 years. The mean age of patients of Punjab 52.6 ± 11.2 and KPK 50.31 ± 12.0. Patients are mostly belonging to urban areas (70%) in Punjab while in KPK from rural areas (62.5%). In Punjab 45% patients have the knowledge about diabetes management and complication while in KPK only 25% affected individuals have awareness about the disease. Results showed that cardiovascular risk in the population of Khyber Pakhtunkhwa is 40%, nephropathy and foot ulcer is present in same percentage (9%). On the other side, the percentage of cardiovascular complication in Punjab is 26%, nephropathy is 14% and foot ulcer is 12%. There is need of Increases awareness of these complications among patients and populations, this facilitate early detection and prevention of these diseases. The earlier diagnosis, timely appropriate treatment may help in avoiding severe, irreversible disability and deformity, which can be done with the tool of patient education and conducting seminar to increase awareness.","PeriodicalId":15597,"journal":{"name":"Journal of diabetes & metabolism","volume":"34 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77682988","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Obesity, Inflammation, Dectin-1 and Exercise Training 肥胖，炎症，Dectin-1和运动训练

Journal of diabetes & metabolism Pub Date : 2018-01-01 DOI: 10.4172/2155-6156.1000788

A. Saeidi, A. Hackney, Vahid Arab-yarmohammadi, Lida Moradi, S. Pashaei, A. Abderrahmane, H. Zouhal

引用次数: 0

Epidermal Growth Factor Therapy Impact on Scar Tissue Resilience of Diabetic Lower Limbs Ulcers-An Enlightening Hypothesis 表皮生长因子治疗对糖尿病下肢溃疡瘢痕组织恢复力的影响——一个具有启发性的假说

Journal of diabetes & metabolism Pub Date : 2018-01-01 DOI: 10.4172/2155-6156.1000798

J. Berlanga-Acosta, Y. Mendoza-Marí, Ariana García-Ojalvo, M. Fernández-Mayola, G. Guillén-Nieto

引用次数: 5

Evaluation of Effect of Vitamin D Supplementation on Glycemic Control in Patients of Type 2 Diabetes Mellitus 补充维生素D对2型糖尿病患者血糖控制效果的评价

Journal of diabetes & metabolism Pub Date : 2018-01-01 DOI: 10.4172/2155-6156.1000806

Deepak S. Bhosle

{"title":"Evaluation of Effect of Vitamin D Supplementation on Glycemic Control in Patients of Type 2 Diabetes Mellitus","authors":"Deepak S. Bhosle","doi":"10.4172/2155-6156.1000806","DOIUrl":"https://doi.org/10.4172/2155-6156.1000806","url":null,"abstract":"Background: In India the number of people with diabetes is increasing day-by-day. Due to a sole “Asian Indian Phenotype,” Indians develop diabetes an era earlier and have an earlier onset of complications. Therefore, it is essential to evaluate more effective treatment strategies at an earlier stage of disease progression. WHO defines Diabetes Mellitus as a metabolic disorder characterized by hyperglycemia, glycosuria, hyperlipidemia, negative nitrogen balance and sometimesketonemia. Aim: To assess and study the effect of Vitamin D supplementation on FBS, PPBS and HbA1clevel in diagnosed patients of Type 2 Diabetes Mellitus. Methods: The present study was Prospective, open label, comparative, randomized, parallel group, two arm interventional study. Comparison of two active treatment groups over a period of six months. Total 120 patients of either sex in the age group of 30 to 60 years with Type 2 Diabetes Mellitus, with HbA1c level >7.0% and <8.5%. The effect of with/without Vitamin Dsupplementwith OHA observed on various parameters i.e. FBG, PPBS, HbA1c. Results: In Group C the mean change in FBS from baseline to 6 months was 162.90 to 127.2 (-35.7); on the other hand, in Group Tfrom baseline to 6 months was 157.90 to 94.93 (-62.97). Whereas, PPBS from 213.40 to 176.17 (-37.23) in Group C; in GroupT from 209.70 to 149.03 (-60.67). On the other hand, in Group C, HbA1c 7.80 to 7.22 (-0.58) and in GroupT, 7.76 to 6.70 (-1.06). Group T statistically highly significant than GroupC in improving glycemic indices. Conclusions: In Treatment Group Vitamin D supplement was responsible for improved levels of FBS, PPBS, HbA1c. In summation, it can be said thatwhen vitamin D levels were adequate control ofglycemic indices.The advantages of the study include: significant reductions, good efficacy, minimal rates of adverse reactions, no toxicity, good compliance.","PeriodicalId":15597,"journal":{"name":"Journal of diabetes & metabolism","volume":"38 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85384787","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 3

Association of Vitamin B12 and Metformin in Type II Diabetes Patients in Bahrain 维生素B12和二甲双胍在巴林II型糖尿病患者中的作用

Journal of diabetes & metabolism Pub Date : 2018-01-01 DOI: 10.4172/2155-6156.1000796

F. Nasser, T. Islam

{"title":"Association of Vitamin B12 and Metformin in Type II Diabetes Patients in Bahrain","authors":"F. Nasser, T. Islam","doi":"10.4172/2155-6156.1000796","DOIUrl":"https://doi.org/10.4172/2155-6156.1000796","url":null,"abstract":"Objective: Metformin therapy is the gold standard treatment for type 2 diabetic patients. Long term use of metformin has been associated with vitamin B12 deficiency. We aimed to study the level of vitamin B12 in type 2 diabetic patients on metformin, and to determine other factors affecting the level of vitamin B12. Methodology: Out of 344 patients with type 2 diabetes that were interviewed from January to December 2015; 304 (91.3%) were investigated for vitamin B12 levels deficiency. The patient’s lab results from 2015-2016 were reviewed from the electronic hospital information system, patient data file. Result: Most of the patients, 56.4% had a normal vitamin B12 level. In 91% of the patients the treating physician had already investigated for serum vitamin B12 level. Dyslipidemia and hypertension were significantly more (p=0.009 and 0.022 respectively) in patients with normal vitamin B12 level. Percentage of normal B12 level patients was higher (p=0.001)even in more than 20 years of metformin use; 46.7% of more than 20 years Metformin users had vitamin B12 level within 301-450 pg/mL and 33.3% had more than 450 pg/mL. Conclusion: We recommend routine screening for basal vitamin B12 level for all patients with type 2 diabetes mellitus (T2DM) at the initiation of metformin therapy with subsequent annual follow up of the level.","PeriodicalId":15597,"journal":{"name":"Journal of diabetes & metabolism","volume":"18 1","pages":"1-6"},"PeriodicalIF":0.0,"publicationDate":"2018-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79742727","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 3

Nutritional Status of Depressive Patients 抑郁症患者的营养状况

Journal of diabetes & metabolism Pub Date : 2018-01-01 DOI: 10.4172/2155-6156.1000786

R. Othman, O. Mziou, A. Gamoudi, A. Smida, Cyrin Souissi, Insaf Loukil, F. Mahjoub, O. Berriche, H. Jamoussi

{"title":"Nutritional Status of Depressive Patients","authors":"R. Othman, O. Mziou, A. Gamoudi, A. Smida, Cyrin Souissi, Insaf Loukil, F. Mahjoub, O. Berriche, H. Jamoussi","doi":"10.4172/2155-6156.1000786","DOIUrl":"https://doi.org/10.4172/2155-6156.1000786","url":null,"abstract":"Depression is a multifactorial disease and nutrition is an important environmental factor in its development and progression. Methods: This is a retrospective study of 50 depressed patients recruited from the outpatient department of psychiatry in Tunisia, as well as 50 controls. Both groups were matched for age and sexResults: A pathological waist circumference was found in 84% of cases against 78% of controls p=0.02. Our patients had a significantly higher intake of carbohydrates and sucrose compared to controls p=0.0001, p=0.02, and significantly lower protein intake (p=0.0001), lipids (p=0.0001), SFA (p=0.01), MUFA (p=0.003), EPA (p=0.02), fibers (p=0.05 ), iron (p=0.0001), zinc (p=0.02), vitamin B9 (p=0.0001), vitamin B1 (p=0.02) vitamin C (p=0.02), calcium (P=0.004). In addition, controls consumed significantly more blue fish, hard cheeses and Olive oil than the patients respectively. Plus the depression was severe, according to the PHQ9 score, plus the intakes were significantly lower in: proteins, carbohydrates, alpha linoleic acid Calcium, consumption of butter and cheese spread, and when depression was certain, according to the HAD, intakes of protein, w3, alpha linoleic acid, corn oil and soybean were low.Conclusions: Our study revealed a very frequent deficit in micro and macronutrients in depressed patients. Some of these deficits, in particular Omega 3, were significantly associated with the severity of depression.","PeriodicalId":15597,"journal":{"name":"Journal of diabetes & metabolism","volume":"9 1","pages":"1-7"},"PeriodicalIF":0.0,"publicationDate":"2018-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81953593","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 5

Prevalence of Hypertension among Patients with Type 2 Diabetes Mellitus and Its Socio Demographic Factors in Nigist Ellen Mohamed Memorial Hospital Hosanna, Southern Ethiopia 埃塞俄比亚南部胡萨纳尼吉斯特埃伦·穆罕默德纪念医院2型糖尿病患者高血压患病率及其社会人口学因素

Journal of diabetes & metabolism Pub Date : 2018-01-01 DOI: 10.4172/2155-6156.1000792

K. Tadesse, H. Amare, Tesfahun Hailemariam, T. Gebremariam

{"title":"Prevalence of Hypertension among Patients with Type 2 Diabetes Mellitus and Its Socio Demographic Factors in Nigist Ellen Mohamed Memorial Hospital Hosanna, Southern Ethiopia","authors":"K. Tadesse, H. Amare, Tesfahun Hailemariam, T. Gebremariam","doi":"10.4172/2155-6156.1000792","DOIUrl":"https://doi.org/10.4172/2155-6156.1000792","url":null,"abstract":"Introduction: World Health Organization revealed 13% of all deaths globally related to hypertension making it an area of prime importance for public health in both developing and developed Country. The problem of hypertension is significant in low and middle income countries like sub-Saharan Africa; however, there are limited studies to report the exact prevalence rate in developing countries, particularly in Ethiopia. Therefore, the aim of this study was to determine prevalence of hypertension among patients with type 2 diabetes mellitus and its socio demographic factors in Nigist Ellen Mohamed Memorial Hospital Hosanna, Southern Ethiopia.Methods: Hospital based cross-sectional study was conducted in 140 randomly selected adult type 2 Diabetes Mellitus patients in Nigist Ellen Mohammed Memorial Hospital, Southern Ethiopia. Data was collected by measuring blood pressure of the study participants by using calibrated devices and interviewer administered questionnaires were used to assess prevalence and socio-demographic factors among the study participants. The collected data were entered, cleared and analyzed by using SPSS 20.0 version.Result: Mean (±SD) age of the clients was 46.5(±11.8) years and majority (63.6%) was male. The mean (±SD) Systolic blood pressure and Diastolic blood pressure of study subjects among type 2 Diabetes Mellitus clients were 135.98 (±17.11) and 88.89 (±12.77) mmHg respectively. More than half (55%) of the type 2 diabetic clients in this study were hypertensive. Finally, there is a significant association between age, gender, marital status, residence and average working hours.Concussion: Prevalence rate of hypertension among type 2 diabetic patients in Hosanna Nigist Ellen Mohammed Memorial Hospital was high. More than half of the study subjects in Nigist Ellen Mohamed Memorial Hospital hospital were hypertensive.","PeriodicalId":15597,"journal":{"name":"Journal of diabetes & metabolism","volume":"435 1","pages":"1-7"},"PeriodicalIF":0.0,"publicationDate":"2018-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76660307","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 25

Relationship between Type 2 Diabetes and Glucose-6 Phosphate Dehydrogenase (G6PD) Deficiency and Their Effect on Oxidative Stress 2型糖尿病与葡萄糖-6磷酸脱氢酶(G6PD)缺乏的关系及其对氧化应激的影响

Journal of diabetes & metabolism Pub Date : 2018-01-01 DOI: 10.4172/2155-6156.1000800

G. Engwa, F. Nwalo, Gregory Eze Chibuzor, Endaline Chiamaka Ejiagha, Micheal Chinweuba Abonyi, T. Ugwu, I. Obiudu, K. N. Agbafor, O. Ojo, B. Ubi

{"title":"Relationship between Type 2 Diabetes and Glucose-6 Phosphate Dehydrogenase (G6PD) Deficiency and Their Effect on Oxidative Stress","authors":"G. Engwa, F. Nwalo, Gregory Eze Chibuzor, Endaline Chiamaka Ejiagha, Micheal Chinweuba Abonyi, T. Ugwu, I. Obiudu, K. N. Agbafor, O. Ojo, B. Ubi","doi":"10.4172/2155-6156.1000800","DOIUrl":"https://doi.org/10.4172/2155-6156.1000800","url":null,"abstract":"Objective: Though the relationship between glucose-6-phosphate dehydrogenase (G6PD) deficiency and type 2 diabetes (T2D) has been reported, their interaction to influence oxidative stress is not fully understood. This study was conducted to investigate the relationship between T2D and G6PD deficiency and assessed their effect on oxidative stress. Methodology: A total of 73 T2D and 75 non-diabetic (ND) out-patients at Enugu State University Teaching Hospital (ESUTH) in Enugu, Nigeria were recruited. They were screened for G6PD deficiency, oxidative stress markers; lipid peroxidation, protein peroxidation and glycated haemoglobin (HbA1c) and antioxidant enzymes; superoxide dismutase (SOD) and catalase activities were assayed. Results: Oxidative stress was influenced by T2D as malondialdehyde (MDA), protein carbonyl and HbA1c levels were significantly higher (p<0.05) in T2D patients compared to ND patients. Significantly (p<0.05) decreased SOD and catalase activity were also observed in T2D patients. G6PD deficiency and T2D showed a significant relationship (p 0.05) interaction between G6PD deficiency and T2D to influence oxidative stress in patients. Conclusion: The interaction between G6PD deficiency and T2D did not influence oxidative stress though there was a possible relationship between G6PD deficiency and T2D in male patients.","PeriodicalId":15597,"journal":{"name":"Journal of diabetes & metabolism","volume":"12 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85964285","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 4