Journal of Dental Sciences最新文献

{"title":"Current challenges of dental laboratory in Taiwan: The perspectives from a senior certified dental technician in a dental laboratory attached to a teaching hospital","authors":"Feng-Chou Cheng , Wei-Chun Lin , Chun-Pin Chiang","doi":"10.1016/j.jds.2024.10.004","DOIUrl":"10.1016/j.jds.2024.10.004","url":null,"abstract":"","PeriodicalId":15583,"journal":{"name":"Journal of Dental Sciences","volume":"20 1","pages":"Pages 678-682"},"PeriodicalIF":3.4,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11762639/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143052727","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Deep learning system for the differential diagnosis of oral mucosal lesions through clinical photographic imaging","authors":"An-Yu Su ,&nbsp;Ming-Long Wu ,&nbsp;Yu-Hsueh Wu","doi":"10.1016/j.jds.2024.10.019","DOIUrl":"10.1016/j.jds.2024.10.019","url":null,"abstract":"<div><h3>Background/purpose</h3><div>Oral mucosal lesions are associated with a variety of pathological conditions. Most deep-learning-based convolutional neural network (CNN) systems for computer-aided diagnosis of oral lesions have typically concentrated on determining limited aspects of differential diagnosis. This study aimed to develop a CNN-based diagnostic model capable of classifying clinical photographs of oral ulcerative and associated lesions into five different diagnoses, thereby assisting clinicians in making accurate differential diagnoses.</div></div><div><h3>Materials and methods</h3><div>A set of clinical images were selected, including 506 images of five different diagnoses. The images were pre-processed and randomly divided into two sets for training and testing the CNN model. The model architecture was composed of convolutional layers, batch normalization layers, max pooling layers, the dropout layer and fully-connected layers. Evaluation metrics included weighted-precision, weighted-recall, weighted-F1 score, average specificity, Cohen’s Kappa coefficient, normalized confusion matrix and AUC.</div></div><div><h3>Results</h3><div>The overall performance for the image classification showed a weighted-precision of 88.8%, a weighted-recall of 88.2%, a weighted-F1 score of 0.878, an average pecificity of 97.0%, a Kappa coefficient of 0.851, and an average AUC of 0.985.</div></div><div><h3>Conclusion</h3><div>The model achieved a decent classification performance (overall AUC=0.985), showing the capacity to discern between benign and malignant potential lesions, and laid the foundation of a novel tool that can help clinical differential diagnosis of oral mucosal lesions. The main challenges were the small and imbalanced dataset. Enlarging the minority classes, incorporating more oral mucosal lesion diagnoses, employing transfer learning and cross-validation might be included in future works to optimize the image classification model.</div></div>","PeriodicalId":15583,"journal":{"name":"Journal of Dental Sciences","volume":"20 1","pages":"Pages 54-60"},"PeriodicalIF":3.4,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11763237/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143052728","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Determination of periodontal bone loss in panoramic radiographs through artificial intelligence analysis","authors":"Chia-Tze Kao,&nbsp;Chih-Jen Tseng,&nbsp;Ming-Che Tsai,&nbsp;Chien-Ning Huang","doi":"10.1016/j.jds.2024.09.031","DOIUrl":"10.1016/j.jds.2024.09.031","url":null,"abstract":"","PeriodicalId":15583,"journal":{"name":"Journal of Dental Sciences","volume":"20 1","pages":"Pages 698-700"},"PeriodicalIF":3.4,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11762257/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143052729","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Digital integration in dental education: A novel self-directed learning model using intraoral scanners for tooth preparation training","authors":"Chia-Ming Liu ,&nbsp;Min-Hsun Hsu ,&nbsp;Min Yee Ng ,&nbsp;Chuan-Hang Yu","doi":"10.1016/j.jds.2024.10.030","DOIUrl":"10.1016/j.jds.2024.10.030","url":null,"abstract":"<div><h3>Background/purpose</h3><div>Traditional dental education faces challenges, such as high student-to-faculty ratios and disruptions like the COVID-19 pandemic, which limit hands-on learning opportunities. Digital technologies, including intraoral scanners, offer potential solutions by improving accuracy and efficiency in clinical practice. This study explored the integration of digital tools in a self-directed learning model for the fixed prosthodontic tooth preparation.</div></div><div><h3>Materials and methods</h3><div>This study, conducted with 81 fourth-year dental students, incorporated digital tools like intraoral scanners into practical training. Students completed a pre-intervention evaluation, followed by training on digital analysis tools, and concluded with a self-directed learning protocol. The study assessed students' theoretical knowledge and practical skills using pre- and post-intervention tests, digital scans, and feedback questionnaires. Statistical analyses, including paired t-tests, evaluated the effectiveness of the intervention.</div></div><div><h3>Results</h3><div>Significant improvements were observed in both theoretical knowledge (pre-test 86 %, post-test 98 %, <em>P</em> = 0.012) and practical skills, with the percentage of “perfect” crown preparations rising from 14 % to 73 % (<em>P</em> &lt; 0.0001). Occlusal reduction showed improvement but remained challenging for some students. Digital tools reduced student anxiety, with 77 % of students reporting decreased anxiety during practical exercises.</div></div><div><h3>Conclusion</h3><div>Integrating digital scanning technology with traditional teaching enhanced student competence in tooth preparation, reduced anxiety, and provided objective evaluation criteria. The self-directed learning model supported skill development and independent problem-solving, indicating the potential for broader application in dental education. Future research should explore long-term impacts on clinical performance and optimize digital tool integration throughout the curriculum.</div></div>","PeriodicalId":15583,"journal":{"name":"Journal of Dental Sciences","volume":"20 1","pages":"Pages 639-645"},"PeriodicalIF":3.4,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11762640/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143052730","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Sodium butyrate activates the extrinsic and intrinsic apoptotic processes in murine cementoblasts","authors":"Shih-Kai Lo ,&nbsp;Ni-Yu Su ,&nbsp;Chun-Chuan Su ,&nbsp;Yu-Chao Chang","doi":"10.1016/j.jds.2024.11.006","DOIUrl":"10.1016/j.jds.2024.11.006","url":null,"abstract":"<div><h3>Background</h3><div><em>/purpose</em>: The metabolic by-product butyric acid of Gram-negative anaerobic bacteria can invoke pathological effects on periodontal cells resulting in inflammation and further destruction of periodontium. However, limited researches on the effects of butyric acid on cementoblasts were reported. Therefore, this study aimed to investigate the type of cell death in murine cementoblast (OCCM.30) caused by adding the different concentrations of sodium butyrate to the cell culture.</div></div><div><h3>Materials and methods</h3><div>OCCM.30 cells were exposed to sodium butyrate (0, 2, 4, 8, 16 mM) for 48 h. Cell viability was determined by microculture tetrazolium assay. Cell cycle distribution and cell death were analyzed by flow cytometry. Caspase-mediated apoptotic cascade was evaluated by Western blot.</div></div><div><h3>Results</h3><div>The concentrations of sodium butyrate≧4 mM were found to inhibit cell viability of OCCM.30 cells in a dose-dependent manner (<em>P</em> &lt; 0.05). Sodium butyrate elevated sub-G1 cell population which exhibited cell apoptosis in OCCM.30 cells (<em>P</em> &lt; 0.05). In addition, early and later apoptotic cells were found in sodium butyrate-induced cell death. Sodium butyrate significantly stimulated the degradation of procaspases-3, -8, and -9 levels, respectively (<em>P</em> &lt; 0.05). Simultaneously, sodium butyrate corresponded to augment the levels of cleaved forms of caspases-3, -8, and -9, respectively (<em>P</em> &lt; 0.05).</div></div><div><h3>Conclusion</h3><div>Taken together, sodium butyrate is a cytotoxic agent and can induce apoptosis on cementoblasts. The pathway involved in apoptosis is activated by caspase family signaling pathways. These evidences may provide a new mechanistic insight into the mechanism of damage of cementoblasts during the development and progression of periodontitis.</div></div>","PeriodicalId":15583,"journal":{"name":"Journal of Dental Sciences","volume":"20 1","pages":"Pages 613-619"},"PeriodicalIF":3.4,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11762920/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143052763","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparison of computed tomographic findings for radiolucent lesions of the mandibular ameloblastoma, odontogenic keratocyst, dentigerous cyst, and simple bone cyst","authors":"Tomoki Sueyoshi ,&nbsp;Junsei Sameshima ,&nbsp;Naoki Kaneko ,&nbsp;Toru Chikui ,&nbsp;Hu Chen ,&nbsp;Shiho Yokomizo ,&nbsp;Haruki Nagano ,&nbsp;Taiki Sakamoto ,&nbsp;Shintaro Kawano","doi":"10.1016/j.jds.2024.04.013","DOIUrl":"10.1016/j.jds.2024.04.013","url":null,"abstract":"<div><h3>Background/purpose</h3><div>Radiolucent lesions of the mandible, including ameloblastoma, odontogenic keratocyst (OKC), dentigerous cyst (DC) and simple bone cyst (SBC), are frequently encountered in clinical practice. However, they vary in type and occasionally in appearance. Each lesion needs a different treatment and approach; therefore, accurate diagnosis is crucial before treatment. However, the radiographic findings, including computed tomography (CT), are often similar. This study aimed to compare the CT findings of 41 ameloblastomas, 74 OKCs, 87 DCs, and 13 SBCs in the mandible.</div></div><div><h3>Materials and methods</h3><div>Patients were evaluated on initial CT images focusing on features such as long/short diameters, relationship with adjacent teeth, cortex appearance, locularity, scalloped margins, and sclerotic rims. Multivariate logistic regression analysis was performed to determine the most useful features for differential diagnosis. Criteria for differential diagnosis were finally established for three lesions, excluding SBC, which had a relatively small number of cases.</div></div><div><h3>Results</h3><div>The relationship with the affected tooth, short diameters, sclerotic rims, and locularity were found to be significant features in the differential diagnosis. Ameloblastomas were characterized by relatively larger short diameters, frequently accompanied by root resorption and adjacent tooth displacement, while SBCs lacked these features. Sclerotic rims were commonly observed in OKCs and DCs, and most DCs were unilocular, containing a crown within the lesion. Based on these results, criteria were established for differential diagnosis with a diagnostic accuracy of 84.2%.</div></div><div><h3>Conclusion</h3><div>This is the first study to attempt to characterize each lesion's radiological features, and these criteria are likely to assist in clinical diagnosis.</div></div>","PeriodicalId":15583,"journal":{"name":"Journal of Dental Sciences","volume":"20 1","pages":"Pages 605-612"},"PeriodicalIF":3.4,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140790774","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Beta-adrenergic receptor antagonist propranolol prevents bisphosphonate-related osteonecrosis of the jaw by promoting osteogenesis","authors":"Qianxin Du ,&nbsp;Qizhang Wang ,&nbsp;Yuhao Wang ,&nbsp;Chengzhi Zhao ,&nbsp;Jian Pan","doi":"10.1016/j.jds.2024.04.016","DOIUrl":"10.1016/j.jds.2024.04.016","url":null,"abstract":"<div><h3>Background/purpose</h3><div>Bisphosphonate-related osteonecrosis of the jaw (BRONJ), a complication arising from the use of bisphosphonates (BPs), inflicts long-term suffering on patients. Currently, there is still a lack of effective treatments. This study aimed to explore the preventive effects of propranolol (PRO) on BRONJ in vitro and in vivo, given PRO's potential in bone health enhancement.</div></div><div><h3>Materials and methods</h3><div>In vitro, effect of PRO on zoledronic acid (ZA)-pretreated bone marrow mesenchymal stem cells (BMSCs) was detected by cell counting kit-8, alkaline phosphatase (ALP) staining, alizarin red staining, real-time quantitative polymerase chain reaction (RT-qPCR) and Western blot. In vivo, forty mice were divided into four groups: control, ZA, PRO, and ZA-PRO. The maxillary extraction sockets sides were analyzed with micro-CT and histomorphometry. Hematoxylin-eosin (H&amp;E), Masson staining, immunofluorescence staining of ALP, bone morphogenetic protein 2 (BMP2), runt-related transcription factor 2 (RUNX2) and TUNEL staining were performed.</div></div><div><h3>Results</h3><div>PRO increased proliferation and osteogenic differentiation of BMSCs. PRO stimulated bone formation and facilitated the healing process in zoledronic acid-induced osteonecrosis of jaw in mouse model. Compared with ZA group, control and PRO group showed more BMP2⁺, RUNX2⁺, and ALP⁺ cells (<em>P</em> &lt; 0.05). However, PRO rescued the decreased expression of ALP, RUNX2, BMP2 due to ZA and decreased the expression of TUNEL (<em>P</em> &lt; 0.05).</div></div><div><h3>Conclusion</h3><div>The findings suggest that propranolol may offer a promising preventive strategy against BRONJ by enhancing bone regeneration. This research contributes to the understanding of the pathogenesis of BRONJ and opens avenues for potential treatments of BRONJ focusing on β-adrenergic signaling.</div></div>","PeriodicalId":15583,"journal":{"name":"Journal of Dental Sciences","volume":"20 1","pages":"Pages 539-552"},"PeriodicalIF":3.4,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141045150","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A comparative analysis of older patients with chewing difficulties due to temporomandibular disorders and tooth loss","authors":"Hye-Mi Jeon ,&nbsp;So-Yeun Kim ,&nbsp;Yong-Woo Ahn ,&nbsp;Soo-Min Ok ,&nbsp;Sung-Hee Jeong ,&nbsp;Hye-Min Ju","doi":"10.1016/j.jds.2024.07.001","DOIUrl":"10.1016/j.jds.2024.07.001","url":null,"abstract":"<div><h3>Background/purpose</h3><div>Chewing difficulty can contribute to psychological stress, which reduces the quality of life for older adults. The purpose of this study was to investigate and analyze the severity of masticatory discomfort, stress response, and sleep disturbance in older patients experiencing masticatory discomfort due to tooth loss or temporomandibular disorders (TMD), to find the further treatment direction for these patients.</div></div><div><h3>Materials and methods</h3><div>A total of 392 patients aged 50 years and older with mastication difficulties were analyzed. Two group of patients, those seeking prosthetic treatment due to tooth loss (n = 193) and those who were referred due to TMD-related pain discomfort (n = 199), were identified. Numeric rating scale (NRS), stress response inventory (SRI), and insomnia severity index (ISI) were used as tools to measure patients’ subjective chewing discomfort, stress response, and sleep status.</div></div><div><h3>Results</h3><div>Chewing discomfort and age were found to be much higher in the prosthetic group than in the TMD group. The TMD group had significantly higher scores in five SRI parameters (tension, anger, depression, fatigue, and frustration) as well as total score and a higher percentage of clinical insomnia compared to prosthetic patients.</div></div><div><h3>Conclusion</h3><div>Since the number of remaining teeth has a significant impact on the masticatory discomfort severity, restoring the occlusion through prosthodontic treatment is important to improve masticatory function. In patients with TMD, it is necessary to assess stress response and sleep quality, and a multidisciplinary treatment approach may be necessary to effectively address masticatory discomfort.</div></div>","PeriodicalId":15583,"journal":{"name":"Journal of Dental Sciences","volume":"20 1","pages":"Pages 342-349"},"PeriodicalIF":3.4,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141692643","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluating the image recognition capabilities of GPT-4V and Gemini Pro in the Japanese national dental examination","authors":"Hikaru Fukuda ,&nbsp;Masaki Morishita ,&nbsp;Kosuke Muraoka ,&nbsp;Shino Yamaguchi ,&nbsp;Taiji Nakamura ,&nbsp;Izumi Yoshioka ,&nbsp;Shuji Awano ,&nbsp;Kentaro Ono","doi":"10.1016/j.jds.2024.06.015","DOIUrl":"10.1016/j.jds.2024.06.015","url":null,"abstract":"<div><h3>Background/purpose</h3><div>OpenAI's GPT-4V and Google's Gemini Pro, being Large Language Models (LLMs) equipped with image recognition capabilities, have the potential to be utilized in future medical diagnosis and treatment, ands serve as valuable educational support tools for students. This study compared and evaluated the image recognition capabilities of GPT-4V and Gemini Pro using questions from the Japanese National Dental Examination (JNDE) to investigate their potential as educational support tools.</div></div><div><h3>Materials and methods</h3><div>We analyzed 160 questions from the 116th JNDE, administered in March 2023, using ChatGPT-4V, and Gemini Pro, which have image recognition functions. Standardized prompts were used for all LLMs, and statistical analysis was conducted using Fisher's exact test and the Mann–Whitney U test.</div></div><div><h3>Results</h3><div>For the 160 JNDE questions, the accuracy rates of GPT-4V and Gemini Pro were 35.0% and 28.1%, respectively, with GPT-4V being the highest, although not statistically significant. Across dental specialties, the accuracy rates of the GPT-4V were generally higher than those of the Gemini Pro, with some areas showing equal accuracy. Accuracy rates tended to decrease with an increased number of images within a question, suggesting that the number of images influenced the correctness of the responses.</div></div><div><h3>Conclusion</h3><div>The overall superior performance of GPT-4V compared to Gemini Pro may be attributed to the continuous updates in OpenAI's model. This research demonstrates the potential of LLMs as educational support tools in dentistry, while also highlighting areas that require further technological development.</div></div>","PeriodicalId":15583,"journal":{"name":"Journal of Dental Sciences","volume":"20 1","pages":"Pages 368-372"},"PeriodicalIF":3.4,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141698741","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"COVID-19 vaccination patterns among oral cancer patients: A comprehensive analysis in a medical center in Taiwan","authors":"Chi-Sheng Cheng ,&nbsp;Han-Pang Liu ,&nbsp;Li-Tzu Lee","doi":"10.1016/j.jds.2024.06.020","DOIUrl":"10.1016/j.jds.2024.06.020","url":null,"abstract":"<div><h3>Background/purpose</h3><div>COVID-19 vaccines are supplied at no-cost to residents as a measure to prevent comorbidities, fatalities, and the increased risk of community transmission, thus protecting public health systems. However, vaccine acceptance among cancer patients remained uncertain. This study aimed to elucidate the vaccination rates among oral cancer patients at a medical center in Taiwan.</div></div><div><h3>Materials and methods</h3><div>We included Individuals who attended for routine follow-ups from January 2021 to December 2022, with a total of 1448 patients subjected to comprehensive analysis. Medical records were reviewed to identify factors influencing vaccine acceptance.</div></div><div><h3>Results</h3><div>Our findings indicate that 1,264 patients received vaccinations, while 184 remained unvaccinated. The vaccination rates among patients in advanced disease stages and those with neck lymph node metastasis (N+) were significantly lower (both P &lt; 0.001). Furthermore, a notable lower vaccination rate was evident among patients receiving active treatment modalities (P &lt; 0.01). Conversely, age, and comorbidities (evaluated using the New Charlson Comorbidity Index), didn't show a significant correlation with vaccination rates. The risk of death caused by oral cancer among vaccinated patients was significantly lower compared to non-vaccinated group (P &lt; 0.001). Logistic regression showed the risk of COVID infection was significant lower in vaccinated group than non-vaccinated group (OR = 0.31, P = 0.034).</div></div><div><h3>Conclusion</h3><div>The risk of COVID-19 infection in oral cancer patients was lower among vaccinated group, and the vaccination was not associated with more mortality. Identifying the characteristics of non-vaccinated individuals and understanding factors influencing vaccine hesitancy in oral cancer patients is vital for developing targeted strategies to improve vaccine uptake.</div></div>","PeriodicalId":15583,"journal":{"name":"Journal of Dental Sciences","volume":"20 1","pages":"Pages 335-341"},"PeriodicalIF":3.4,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141705906","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}