Journal of Dental Sciences最新文献

{"title":"The first Taiwanese female dentist in Taiwan","authors":"Feng-Chou Cheng , Ling-Hsia Wang , Julia Yu-Fong Chang, Chun-Pin Chiang","doi":"10.1016/j.jds.2024.10.005","DOIUrl":"10.1016/j.jds.2024.10.005","url":null,"abstract":"","PeriodicalId":15583,"journal":{"name":"Journal of Dental Sciences","volume":"20 1","pages":"Pages 695-697"},"PeriodicalIF":3.4,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11763607/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143052783","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The relationship between pneumonia and dental visits in patients with cerebral palsy: A nationwide registry-based cohort study in Taiwan","authors":"Fu-Hsuan Liu ,&nbsp;Jing-Yang Huang ,&nbsp;Yu-Chao Chang","doi":"10.1016/j.jds.2024.09.019","DOIUrl":"10.1016/j.jds.2024.09.019","url":null,"abstract":"<div><h3>Background/purpose</h3><div>In general, improving oral health can reduce the risk of pneumonia. The purpose of this retrospective cohort study was to investigate the risk of pneumonia between cerebral palsy (CP) cohort and non-CP cohort as well as the association of pneumonia with the number of dental visits in CP patients in Taiwan.</div></div><div><h3>Materials and methods</h3><div>We identified 10,544 patients who were diagnosed with CP between 2010 and 2019 from the Taiwan National Health Insurance Research Database. 63,264 individuals who had never been diagnosed with CP were captured and matched in a 6:1 ratio. Cox proportional hazard regression analysis was adopted to assess the hazard ratio (HR) of pneumonia between CP cohort and non-CP cohort.</div></div><div><h3>Results</h3><div>Our findings demonstrated that CP cohort had 2.619-fold risk for pneumonia as compared with non-CP cohort after adjustment (95 % CI = 2.574–2.813, <em>P</em> &lt; 0.0001). Cox regression analysis indicated that the CP group had significantly higher incidence risk of pneumonia (log rank <em>P</em> &lt; 0.0001). Higher risks of pneumonia in CP patients were associated with younger age, and lower urbanization level. Some comorbidities as well as history of pneumonia had the higher aHR for pneumonia within 180 days prior to index date. In addition, there was a positive association with the more than two dental visits for the decrease 0.887-fold incidence of pneumonia in CP-cohort as compared with no dental visit (95 % CI: 0.799–0.984).</div></div><div><h3>Conclusion</h3><div>Taken together, CP patients had a higher risk of pneumonia. Dental visits are beneficial for preventing the risk of pneumonia in CP patients. The patients with CP should receive regular dental checkup.</div></div>","PeriodicalId":15583,"journal":{"name":"Journal of Dental Sciences","volume":"20 1","pages":"Pages 118-125"},"PeriodicalIF":3.4,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11762931/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143052789","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Usefulness of bilateral sagittal split osteotomy with posterior bending osteotomy fixed by absorbable systems for facial asymmetry","authors":"Shinsuke Yamamoto,&nbsp;Keigo Maeda,&nbsp;Naoki Taniike","doi":"10.1016/j.jds.2024.09.028","DOIUrl":"10.1016/j.jds.2024.09.028","url":null,"abstract":"","PeriodicalId":15583,"journal":{"name":"Journal of Dental Sciences","volume":"20 1","pages":"Pages 701-703"},"PeriodicalIF":3.4,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11762623/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143052798","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Using optimization approach to design dental implant in three types of bone quality - A finite element analysis","authors":"Chih-Ling Chang ,&nbsp;Jing-Jie Chen ,&nbsp;Chen-Sheng Chen","doi":"10.1016/j.jds.2024.09.017","DOIUrl":"10.1016/j.jds.2024.09.017","url":null,"abstract":"<div><h3>Background/Purpose</h3><div>The use of finite element (FE) analysis in implant biomechanics offers many advantages over other approaches in simulating the complexity of clinical situations. The aim of this study was to perform an optimization analysis of dental implants with different thread designs in three types of bone quality.</div></div><div><h3>Materials and methods</h3><div>The three-dimensional FE model of a mandibular bone block with a screw-shaped dental implant and superstructure was simulated. In the optimization analysis, the design variables included the thread pitch and the thread depth of the implant. The objective was to minimize the displacement of the implant to the target value. Three FE models with different bone qualities (D2: better bone quality; D3: ordinary bone quality; D4: poor bone quality) were created.</div></div><div><h3>Results</h3><div>The FE results showed that the displacement of the implant and the stress of the cortical bone increased, while the Young's modulus of the cancellous bone decreased. In the D2 bone, changing the thread pitch and thread depth had little effect on cortical stress and implant displacement. However, in D3 and D4 bone, increasing thread depth reduced cortical stress by 40 % and implant displacement by at least 9 %.</div></div><div><h3>Conclusion</h3><div>Adjusted thread depth for D3 and D4 bone would reduce crestal bone stress and increase implant stability, but only a little alteration on crestal bone stress and implant stability for D2 bone.</div></div>","PeriodicalId":15583,"journal":{"name":"Journal of Dental Sciences","volume":"20 1","pages":"Pages 126-136"},"PeriodicalIF":3.4,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11762967/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143052801","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect of a modified methyl methacrylate-p-styrene sulfonic acid copolymer-based gel desensitizer on dentin permeability and tubule occlusion in human dentin in vitro","authors":"Athimas Chatanan ,&nbsp;Kanittha Kijsamanmith ,&nbsp;Varunee Kerdvongbundit ,&nbsp;Thanwarat Aroonrangsee ,&nbsp;Noppakun Vongsavan","doi":"10.1016/j.jds.2024.04.017","DOIUrl":"10.1016/j.jds.2024.04.017","url":null,"abstract":"<div><h3>Background/purpose</h3><div>Tubular occlusion is an effective method to treat dentin hypersensitivity. This study aimed to determine the effect of a modified methyl methacrylate-p-styrene sulfonic acid copolymer-based gel desensitizer on dentin permeability and tubule occlusion in extracted human premolars.</div></div><div><h3>Materials and methods</h3><div>Hydraulic conductance (HC) measurement (n = 50) and scanning electron microscopy (SEM; n = 64) were performed. Tooth specimens were divided into 6 groups and treated with: G1, distilled water for 30 s; G2, distilled water for 5 min; G3, gel desensitizer for 30 s; G4, gel desensitizer for 5 min; G5, 3% potassium oxalate for 30 s; G6, 3% potassium oxalate for 5 min. HC of dentin were measured before and after 30 s-etching with 35% phosphoric acid, at 0, 30, 60 min after group treatment and after 5-min acid challenge with 6% citric acid. The degree of tubule occlusion and the penetration depth of each agent were also determined. ANOVA and multiple comparison tests were used for data analysis.</div></div><div><h3>Results</h3><div>G3, G4, G5 and G6 significantly decreased in HC after group treatment every observation period, compared to after acid-etching (<em>P</em> &lt; 0.001), and had 100% degree of tubule occlusion with penetration depth about 7.62, 7.94, 8.59 and 8.66 μm, respectively. However, G6 showed the greatest reduction in HC (<em>P</em> &lt; 0.05).</div></div><div><h3>Conclusion</h3><div>Gel desensitizer treatment, for only 30 s, could reduce dentin permeability and completely occlude the dentinal tubules, even though after acid challenge. However, 5-min treatment with potassium oxalate showed the greatest decrease in dentin permeability.</div></div>","PeriodicalId":15583,"journal":{"name":"Journal of Dental Sciences","volume":"20 1","pages":"Pages 596-604"},"PeriodicalIF":3.4,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11762247/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143052759","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"From microscope to masterpiece: Validating the role of artistic competition in enhancing dental students' engagement in histological study","authors":"Chuan-Hang Yu ,&nbsp;Chun-Pin Chiang","doi":"10.1016/j.jds.2024.11.008","DOIUrl":"10.1016/j.jds.2024.11.008","url":null,"abstract":"<div><h3>Background/purpose</h3><div>Our previous study found that the integration of arts into the dental education through an innovative photomicrograph competition can increase the dental students' interests in learning microscopic lessons. This study aimed to validate whether the same photomicrograph competition still had its effectiveness to promote the students' interests in learning microscopic lessons.</div></div><div><h3>Materials and methods</h3><div>A photomicrograph competition was organized for the 477 dental students. The students captured artistic images from the oral histology and oral pathology slides. The entries were evaluated through a peer vote. A post-competition survey was performed to assess the students' perceptions of the activity's impact on their learning interest, satisfaction, and views on the potentially broader implementation.</div></div><div><h3>Results</h3><div>The photomicrograph competition gathered a 29 % overall participation rate, with the highest engagement from the third-year (66 %) and second-year (50 %) dental students. Of the participants, 73 % reported an increase in interest in the microscopic lessons, 78 % expressed satisfaction with the photomicrograph competition activity, and 80 % supported its annual continuation. Furthermore, 68 % of the students believed the photomicrograph competition could be adopted by all dental schools in Taiwan.</div></div><div><h3>Conclusion</h3><div>This study confirms the effectiveness of integrating arts into the dental education through the photomicrograph competitions. The consistent positive outcomes over time suggest the long-term viability and benefits of this approach in improving the students’ histological studies, particularly among the second-year and third-year dental students. A strong support for the continued and broader implementation indicates a high potential for the incorporation of photomicrograph competitions in the dental curricula.</div></div>","PeriodicalId":15583,"journal":{"name":"Journal of Dental Sciences","volume":"20 1","pages":"Pages 626-631"},"PeriodicalIF":3.4,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11762922/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143052395","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect of pulp-chamber lateral wall thickness and number on fracture resistance in endocrown-restored molars: An in vitro study","authors":"Zhi Li ,&nbsp;Jun-Xin Zhu ,&nbsp;Yong-Xiang Xu ,&nbsp;Xu-Dong Bao ,&nbsp;Xiao-Yan Wang","doi":"10.1016/j.jds.2024.05.012","DOIUrl":"10.1016/j.jds.2024.05.012","url":null,"abstract":"<div><h3>Background/purpose</h3><div>It remains unclear how the thickness and number of pulp-chamber lateral walls (PCLWs) affects fracture resistance in endocrown-restored teeth.</div></div><div><h3>Materials and methods</h3><div>64 mandibular molars were collected and randomly divided into eight groups (n = 8). In group C (control group), the teeth were untreated. In groups T1, T2, and T3, the teeth were subjected to endodontic treatment and restored with nanoceramic endocrowns exhibiting different PCLW thicknesses (T1: 0.5 mm, T2: 1.0 mm, and T3: 1.5 mm). In groups N1, N2, N3, and N4, the numbers of missing PCLWs in prepared teeth were one (N1), two (N2), three (N3), and four (N4). All restored teeth were subjected to axial loading until fracture using a universal testing machine. The mean fracture loads were recorded and compared by one-way analysis of variance; the fractured samples were observed under a stereo microscope.</div></div><div><h3>Results</h3><div>The results showed no statistically significant differences in fracture load among groups T1, T2, and T3 (<em>P</em> &gt; 0.05). Although the fracture loads gradually decreased as the number of missing PCLWs increased, there were no statistically significant differences in fracture load among groups C, N1, N2, and N3, and N4 (<em>P</em> &gt; 0.05).</div></div><div><h3>Conclusion</h3><div>Both thickness and remaining number of PCLW does not affect fracture resistance in endodontically treated molars restored with nanoceramic endocrowns.</div></div>","PeriodicalId":15583,"journal":{"name":"Journal of Dental Sciences","volume":"20 1","pages":"Pages 470-476"},"PeriodicalIF":3.4,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141141466","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Influence of dual-cure resin-cement curing modes on gingival cytotoxicity and inflammatory responses","authors":"Takeru Kondo ,&nbsp;Hiroaki Kakinuma ,&nbsp;Sara Ambo ,&nbsp;Koki Otake ,&nbsp;Yumi Sato ,&nbsp;Hiroshi Egusa","doi":"10.1016/j.jds.2024.04.019","DOIUrl":"10.1016/j.jds.2024.04.019","url":null,"abstract":"<div><h3>Background/purpose</h3><div>Dual-cure resin-cements are used for various dental restorations. However, whether the curing modes of these resin-cements influence gingival inflammation remains unclear. Hence, herein, we evaluated the effects of dual-cure resin-cement curing modes on gingival cytotoxicity and inflammatory responses.</div></div><div><h3>Materials and methods</h3><div>Specimens were prepared using two dual-cure resin-cements—RelyX Unicem 2 (RU) and G-CEM ONE (GO)—by light-cure or self-cure modes. Degree of conversion (DC) and monomer elution of the resin-cements were measured using Fourier-transform infrared spectroscopy and high-performance liquid chromatography, respectively. Human gingival fibroblasts (GFs) and macrophages were cultured on resin-cements, and inflammatory cytokine levels, intracellular reactive oxygen species (ROS) generation, and mitogen-activated protein (MAP) kinase activation were evaluated.</div></div><div><h3>Results</h3><div>Light-cured (LC) resin-cements exhibited significantly higher DC and lower monomer elution than did self-cured (SC) resin-cements. Triethyleneglycol dimethacrylate (TEGDMA) and urethane dimethacrylate (UDMA) were substantially eluted from RU and GO, respectively. Neither LC resin-cement exhibited cytotoxicity and enhanced pro-inflammatory cytokine expression in GFs and macrophages. However, both SC resin-cements significantly decreased cell numbers and promoted cellular inflammatory responses. SC generated higher intracellular ROS levels compared to that seen with LC, and different patterns of MAP kinase activation were observed between SC–RU and SC–GO.</div></div><div><h3>Conclusion</h3><div>Compared with LC dual-cure resin-cements, SC dual-cure resin-cements show stronger cytotoxicity and elicit greater inflammatory responses in gingival cells owing to residual monomers (e.g., TEGDMA and UDMA) by activating MAP kinases in GFs and macrophages. Clinicians should ensure adequate light irradiation during prosthesis cementation and make efforts to remove the excess cement.</div></div>","PeriodicalId":15583,"journal":{"name":"Journal of Dental Sciences","volume":"20 1","pages":"Pages 586-595"},"PeriodicalIF":3.4,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11762211/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143052358","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Influence of operator experience on the complete-arch accuracy and time-based efficiency of three intraoral scanners","authors":"Wei-Chun Lin ,&nbsp;Chian-Chuen Lee ,&nbsp;Sheng-Yang Lee ,&nbsp;Chiao-Yun Peng ,&nbsp;Chia-Cheng Lin","doi":"10.1016/j.jds.2024.11.009","DOIUrl":"10.1016/j.jds.2024.11.009","url":null,"abstract":"<div><h3>Background/purpose</h3><div>The performance of intraoral scanners (IOSs) relies on the operator's skills. However, whether operator experience influences IOS accuracy remains unclear. This study investigated the effect of operator experience on the trueness accuracy and time-based efficiency of IOSs.</div></div><div><h3>Materials and methods</h3><div>Thirty operators were equally divided into two groups on the basis of their IOS-handling experience. Each operator performed simulation scans of a maxillary model in a training dummy by using three IOSs: CEREC Omnicam, Primescan, and Aoralscan 3. A total of 90 scans were generated, and the scan time for image acquisition and the render time required for an IOS to generate a three-dimensional image were recorded. The trueness of each scan was calculated by comparing with a reference scan obtained from an industrial high-precision scanner. The <em>t</em> test and the ANOVA followed by the Tukey post hoc test were used to determine statistical differences. Significance was set at <em>P</em> &lt; 0.01.</div></div><div><h3>Results</h3><div>For the three IOSs, no significant difference was noted in trueness accuracy, scan time, or render time between inexperienced and experienced operators. For both inexperienced and experienced operators, Omnicam had significantly less accuracy and longer scan time than did the other IOSs; the render time was significantly shorter for Aoralscan 3 than for the other IOSs.</div></div><div><h3>Conclusion</h3><div>Operator experience does not substantially influence the trueness accuracy and time-based efficiency of IOSs; these factors vary across IOS types. The render time for obtaining three-dimensional images is a significant feature for improving the time-based efficiency of IOSs.</div></div>","PeriodicalId":15583,"journal":{"name":"Journal of Dental Sciences","volume":"20 1","pages":"Pages 620-625"},"PeriodicalIF":3.4,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11762679/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143052359","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"miR-508-5p suppresses osteogenic differentiation of human periodontal ligament stem cells via targeting sex-determining region Y-related HMG-box 11","authors":"Jing Guo,&nbsp;Xiang-Ying Ouyang,&nbsp;Jian-Ru Liu,&nbsp;Wen-Yi Liu,&nbsp;Yuan-Bo Wang","doi":"10.1016/j.jds.2024.08.012","DOIUrl":"10.1016/j.jds.2024.08.012","url":null,"abstract":"<div><h3>Background/Purpose</h3><div>The local inflammatory microenvironment created by periodontitis negatively impacts periodontal tissue regeneration, necessitating the development of methods to enhance the regenerative capacity of stem cells. This study explored the regulatory role and underlying mechanism of miR-508-5p in the osteogenic differentiation of human periodontal ligament stem cells (hPDLSCs).</div></div><div><h3>Materials and methods</h3><div>The regulatory roles of miR-508–5p in osteogenic differentiation of hPDLSCs were investigated through its inhibition or overexpression. Expression of the sex-determining region Y-related HMG-box 11 (SOX11) and osteogenic markers was analyzed using Western blot and real-time PCR. Osteogenesis was measured using alizarin red S (ARS) staining and alkaline phosphatase (ALP) staining. A dual luciferase reporter assay was performed to confirm SOX11 as a target of miR-508-5p.</div></div><div><h3>Results</h3><div>During the osteogenic differentiation of hPDLSCs, miR-508-5p expression level gradually decreased, while that of SOX11 increased. miR-508-5p inhibition significantly promoted osteogenesis in hPDLSCs, while overexpression inhibited the process. SOX11 overexpression reversed the suppressive effects of miR-508-5p on the osteogenic differentiation of hPDLSCs. miR-508–5p downregulation significantly increased SOX11; a dual luciferase reporter assay provided evidence for their direct targeting.</div></div><div><h3>Conclusion</h3><div>miR-508-5p downregulation promotes the osteogenic differentiation of hPDLSCs by targeting SOX11.</div></div>","PeriodicalId":15583,"journal":{"name":"Journal of Dental Sciences","volume":"20 1","pages":"Pages 201-211"},"PeriodicalIF":3.4,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11763229/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143052625","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}