Clinical Medicine And Health Research Journal最新文献

{"title":"Scarcity of Awareness and Level of Misconception about Thalassemia around the Population of Kolkata and Neighbouring Places- A Preliminary Study","authors":"Rittika Majumdar, Shuvam Mondal, T. Rudra","doi":"10.18535/cmhrj.v3i01.142","DOIUrl":"https://doi.org/10.18535/cmhrj.v3i01.142","url":null,"abstract":"Thalassemia is a genetic disorder caused by the inheritance of mutated and abnormal genes involved in the production of hemoglobin from the parents. Thalassemia is most seen in Mediterranean region, Middle East, South-East Asia, Africa, and Indian subcontinent. It is also known as The Mediterranean Disease. The study aims to focus on the awareness of thalassemia among the population of Kolkata, emphasizing on college and university going students. A questionnaire-based survey was conducted among 55 willing participants in a 6-week tenure, from June to July 2022. The study used data visualization method and descriptive statistics for understanding the level of awareness, perception about thalassemia among the participants. The mean knowledge percentage was 25.43% which was analyzed by calculating the points obtained by the participants allotted to each question, the point range was 2­–22 in which only 6 i.e., 10.9% of people had an excellent knowledge of the disease. The points acquired ranged from 8–22 i.e., 4 to 11 questions, more than half of the participants (60%, 33) believe there is a cure for thalassemia and almost 44% (24) participants believe screening of thalassemia can be done only by blood tests. This work focuses on the scarcity of information and degree of misconception about thalassemia. It calls for an urgent, routine need of thalassemia awareness program in the population.","PeriodicalId":155428,"journal":{"name":"Clinical Medicine And Health Research Journal","volume":"60 3","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"120915279","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Current Aspects of Non Hodgkin Lymphoma (NHL) In Bangladesh: A Mini Review","authors":"Md. Khaledur Rahman Bhuiyan, Dr.Mahmudur Rahman, Swapan Kumar Das, Dr. Syed Mahmood Shahidul Islam, Dr. Faiza Mahmud, A. Mukit, J. A. Malik, Md. Rezwan Ahmed Mahedi, Sadia Afrin, Nikolaos Symros","doi":"10.18535/cmhrj.v3i01.130","DOIUrl":"https://doi.org/10.18535/cmhrj.v3i01.130","url":null,"abstract":"Approximately 90% of all lymphomas are classified as non-Hodgkin lymphoma (NHL), a subtype of lymphoma originating in other parts of the immune system outside the lymph nodes. Adult NHL may be classified as either B-cell lymphoma, T-cell lymphoma, or natural killer cell lymphoma, according to the World Health Organization's (WHO) categorization system. According to the statistics, about one and a half million new people are diagnosed with cancer in a year in Bangladesh, among which more than seven thousand people are affected by various blood cancers. Non-Hodgkin and Hodgkin lymphoma, leukaemia, and myeloma belong to blood cancers. Treatment also varies depending on the disease's type and stage or risk. The paper aims to express the current condition of NHL & the treatment approach for this disease by analysing the literature and data of Bangladesh.","PeriodicalId":155428,"journal":{"name":"Clinical Medicine And Health Research Journal","volume":"44 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124221745","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cardioprotective Diet: A Possibility of Diet Therapy Treatment","authors":"Luz Edith Garcia, Cintra Patricia, Holsbach Anderson Leão Nogueira, Nunes Ângela Alves, Anastácio de Oliveira Thaís","doi":"10.18535/cmhrj.v2i6.131","DOIUrl":"https://doi.org/10.18535/cmhrj.v2i6.131","url":null,"abstract":"The Brazilian Cardioprotective Diet is a diet for patients with heart disease, but it provides health benefits when used as an adjuvant in the prevention and treatment of diseases that have food as one of the factors for their development. It was developed by Hcor in partnership with the Ministry of Health in 2018. It classifies and recommends the consumption of foods by groups: green, yellow, and blue, using the Food Guide for the Brazilian Population as a referência. The objective of this study was, through a literature review, to find scientific data on the cardioprotective diet. This diet indicates the inclusion or exclusion of food from the values of food density (kcal, saturated fat, cholesterol, and sodium).Studies have pointed out that the excessive intake of ultra-processed foods is associated with practicality of eating, afforda prices, and easy availability of products, and therefore these foods have become cheaper compared to fresh, minimally processed foods, and the ultra-processed foods are the main responsible for the increase in non-transmissible chronic diseases. The cardioprotective diet shows the significant effect on the modulation of inflammatory response, through the intake of several nutrients and bioactive compounds from food, which act by activating the signaling pathways involved in the synthesis of inflammatory biomarkers. Therefore, although there are few published studies on cardioprotective food and being it effective in the secondary treatment of chronic noncommunicable diseases, it is necessary to conduct research among nutritionists to know the difficulties of assistance within the Public Health System.","PeriodicalId":155428,"journal":{"name":"Clinical Medicine And Health Research Journal","volume":"8 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-12-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115030008","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Hyperthyroidism and Covid-19, Early or Late: A Case Series from South-West Nigeria","authors":"A. Esan, Martins Ehizode Emuze, O. Adekanmbi","doi":"10.18535/cmhrj.v2i6.136","DOIUrl":"https://doi.org/10.18535/cmhrj.v2i6.136","url":null,"abstract":"The Coronavirus disease 2019 (COVID-19) pandemic has put the world on its toes for more than 2 years. It is caused by a novel virus called severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Initial symptoms associated with the virus were mainly respiratory in nature but over time, varied presentations have been noted in persons infected with the disease. Research has shown that COVID-19 can cause both pulmonary and systemic inflammation, which may result in multi-organ dysfunction. The effects of COVID-19 on metabolism including glucose regulation and diabetes mellitus have been highlighted in literature and it is now known that persons with poorly controlled diabetes will most likely have a poor clinical outcome when infected with SARS-CoV-2. Biochemical abnormalities of the thyroid hormones during and post-COVID infection have been noted by some authors, however, there is scanty information available in sub-Saharan Africa. The essence of this case series is to document the experience of an endocrine facility as regards thyroid abnormalities observed in persons who presented with confirmed COVID-19 infection and COVID-19 related symptoms without confirmation by PCR.","PeriodicalId":155428,"journal":{"name":"Clinical Medicine And Health Research Journal","volume":"8 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-12-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128158277","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect of a low-carb and low-calorie diet on weight loss in overweight or obese patients","authors":"Francisca Santos Rodrigues da Silva, Ana Paula Moreira Carvalho Alves, Ezequiel António Marques Pinto","doi":"10.18535/cmhrj.v2i6.134","DOIUrl":"https://doi.org/10.18535/cmhrj.v2i6.134","url":null,"abstract":"As obesity is the epidemic of the 21st century and has become a major public health problem worldwide, being responsible for the vast majority of chronic diseases, a prospective convenience study was carried out on the effect of low-carb and low-calorie diets in people with overweight and/or obesity, at the Centro Hospitalar Universitário do Algarve (CHUA), Portimão unit, at the external nutrition appointment. The study lasted three months. As a result, there is a decrease in weight, Body mass index, fat mass (FM), and visceral fat (VF) in users who had nutritional intervention, with statistical significance (weight (p=0.012), BMI (p=0.012), FM (p<0.001), and VF (p=0.003). In short, concludes that, throughout the appointments, there were statistically significant reductions in weight, BMI, fat mass and visceral fat.","PeriodicalId":155428,"journal":{"name":"Clinical Medicine And Health Research Journal","volume":"15 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-12-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128600833","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Case of Subarachnoid Haemorrhage and Postop Cerebral Vasospasm Successfully Healed Using Yoga Prana Vidya Energy Healing Techniques as Complementary Therapy","authors":"Ganesh Hr, A. Kumar M., Saloni Dilip Shah, Venkata Satyanarayana Nanduri","doi":"10.18535/cmhrj.v2i6.132","DOIUrl":"https://doi.org/10.18535/cmhrj.v2i6.132","url":null,"abstract":"Introduction: Subarachnoid haemorrhage (SAH) refers to the bleeding in the space surrounding the brain and its membrane and occurs usually due to the bulging or ruptures in the blood vessels of the brain. Following SAH, cerebral vasospasm can occur which can lead to sudden death or brain damage if not treated correctly and immediately. This paper presents a case of a 35 years old male patient with SAH & cerebral vasospasm, who completely recovered after a successful surgery, and using Yoga Prana Vidya Healing techniques as complementary therapy.\u0000Method: This paper uses case study method going through patient medical records, YPV healers’ records and patient feedback. \u0000Results: The patient recovered within 4 hours from a complicated 7+ hours of SAH surgery, was able to recognize people and respond to body movements and also use the washroom comfort ability by himself. Within 14 days of YPV healing, the patient was discharged from the hospital and within 2 months of the surgery the patient resumed office and started leading normal life.\u0000Conclusion: It is observed that with Yoga Prana Vidya, which is a no-touch no-drug and distant healing modality, faster and complete recovery of patients takes place when used complementarily to medical and surgical treatments such as this case. YPV Healing techniques have been known to increase the life energy or prana in the energy body of a person thereby helping them with a speedy recovery. There is a great scope for further research on this topic using appropriate methodology and sample size.","PeriodicalId":155428,"journal":{"name":"Clinical Medicine And Health Research Journal","volume":"62 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-12-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123595323","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Surgical Management of Lutembacher’s Syndrome in Congestive Cardiac Failure: A Case Report & Review of Literature","authors":"R. Yadav, S. Pathak, Shubha Gupta","doi":"10.18535/cmhrj.v2i6.127","DOIUrl":"https://doi.org/10.18535/cmhrj.v2i6.127","url":null,"abstract":"Introduction: Lutembacher’s syndrome is a rare clinical entity. In 1916, French physician Rene Lutembacher described his first case of 61 years old woman with a combination of congenital ASD with acquired MS. But he attributed this mitral lesion to congenital mitral stenosis. The definition of this syndrome named after him has undergone many changes since then. The current consensus defines Lutembacher Syndrome (LS) as any combination of ASD (congenital or iatrogenic) and MS (congenital or acquired). The clinical presentation of LS is a result of the interplay between the size of ASD, the severity of MS, pulmonary vascular resistance and RV compliance. Financial constraints also add to the delayed diagnosis and adequate treatment in our part of the world. Here we have discussed a case of LS with severe TR and moderate PAH in congestive cardiac failure which was successfully treated by surgery thereby demonstrating cost-effective and successful surgical management of a rare cardiac disease where vascular resistance, compliance, size and severity of lesions interplay causing cardiac failure.\u0000Case report: A 42 years old thin built, poorly nourished housewife presented with chest discomfort and fatigue for the last 4 years. She was diagnosed with an atrial septal defect four years back but could not receive appropriate treatment due to financial constraints. For the last 15 days, she had breathlessness even at rest and paroxysmal episodes that interrupted her sleep. Icterus and pedal edema was also present. As we evaluated the patient, her clinical examination could not be entirely explained by ASD alone. Soon, our suspicion of LS was confirmed by TTE and the diagnosis of Lutembacher Syndrome with Severe Tricuspid Regurgitation with Moderate PAH was made. As the patient presented to us with atrial fibrillation & heart failure, she was admitted for optimization. The patient was then successfully managed by MVR [#27 SJM, metallic] with pericardial patch closure of ASD with Devaga’s Tricuspid Valve annuloplasty and discharged on a postop day 11.\u0000Conclusions: Early diagnosis and surgical treatment bear a good prognosis and prolong survival. If a patient is diagnosed late, pulmonary hypertension and heart failure set in and the outcome becomes poor. The higher cost of surgical intervention and low socio-economic distribution of the disease in developing countries like India should not challenge the patient’s right to receive the standard treatment.","PeriodicalId":155428,"journal":{"name":"Clinical Medicine And Health Research Journal","volume":"10 4","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-12-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"113975034","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of Serum Calcitonin, Creatinine and Uric Acid in Ckd Complicated By Dysthyroidism","authors":"Christian Ugege, Ehiremen S. E., Eidangbe A.P, Ohiwerei W.O., Otaye O.M","doi":"10.18535/cmhrj.v2i6.126","DOIUrl":"https://doi.org/10.18535/cmhrj.v2i6.126","url":null,"abstract":"This study evaluated the serum calcitonin, creatinine and uric acid levels in chronic kidney diseases (CKD) complicated by dysthyroidism. A total of 119 participants were recruited in this study, majority of who were males. This may likely be as a result of the bread winning role of men and hence are often economically empowered to seek health care. The higher proportion of males in this study could reflect a positive change in health seeking behavior of the male gender. Majority of the participants in this study were between the ages of 30 to 68 years with a median of 49 years. The high prevalence of CKD among this age group can be attributed to underlying pathologies such as hypertension, diabetes or both. Result from this study showed a significant increase (p ≤ 0.05) in serum calcitonin,TSH, creatinine and uric acid levels of CKD subjects when compared to the control and a significant decrease (p ≤ 0.05) was observed in serum T3 and T4 levels of CKD subjects were observed.T3 value showed significant decrease when the value of T3 gotten from stage 3,4 and 5 of CKD subjects were compared.","PeriodicalId":155428,"journal":{"name":"Clinical Medicine And Health Research Journal","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-12-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130744969","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Formulation Development & Evaluation of Controlled Drug Delivery System: An Overview","authors":"Shimanta Paul, Tausif Ahmed, Shanzid Hasan, Md. Khaledur Rahman Bhuiyan, Swapan Kumar Das, Nikolaos Symros","doi":"10.18535/cmhrj.v2i6.117","DOIUrl":"https://doi.org/10.18535/cmhrj.v2i6.117","url":null,"abstract":"The therapeutic effect is brought about by the drug delivery system dispensing the active medicinal ingredient. Due to fluctuations in plasma drug levels, traditional drug delivery devices have poor bioavailability and cannot generate a continuous release. The drug must also be supplied at a tightly regulated rate and to the correct location for it to be most effective and safe. To solve the problems inherent in the current methods of administering medication, scientists are working on perfecting controlled drug delivery systems. Controlled pharmaceutical delivery systems have come a long way in the last twenty years, from bulk distribution to nanoscale precision to smart, patient-specific dosing. The paper's initial portion provides background knowledge on drug delivery methods, emphasizing pharmacokinetics. The article also discusses the pros and cons of more conventional drug delivery methods. Controlled drug delivery systems' design factors, categorizations, and schematics are also discussed in length. In addition, recent advances in nano-drug delivery, targeted, and innovative drug delivery utilizing stimuli-responsive, intelligent biomaterials are discussed. The limitations of regulated medicine distribution and some possible solutions are discussed at the end of the study.","PeriodicalId":155428,"journal":{"name":"Clinical Medicine And Health Research Journal","volume":"10 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-11-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133115233","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparison of Pin Site Infection Rate between Schanz Screws and K-Wires in Ilizarov Fixator for Tibial Fracture","authors":"Ziyad Ahmad, Imdad Ullah, M. Izhar, Arsalan Hakim, Wajid Ullah, N. Ahmad","doi":"10.18535/cmhrj.v2i6.121","DOIUrl":"https://doi.org/10.18535/cmhrj.v2i6.121","url":null,"abstract":"Objective: Comparison of pin site infection rate between schanz screws and k-wires in ilizarov fixator for tibial fracture\u0000Methodology: It was a randomized control trial, conducted at department of Orthopedics, Khyber Teaching Hospital, MTI, and Peshawar from July 2021 to June 2022. Sampling Technique was Non-probability consecutive sampling. Patients were divided into two groups using computer generated random sequence number. Patients in group A were stabilized using K-wires and patients in group B were stabilized using k-wire and schanz screws. Data were entered in specially designed proforma.\u0000Result: Mean age in group A patients was 35±2.77 years, while in group B it was 38±3.12 years. Gender distribution between two groups was analyzed. In Group A 72.3% were males and 27.7 % females while in Group B patients, 70% were males and 30% were females. Mean duration from injury to surgery was 5 days with SD±2.12 in group A, while 5.5±2.37 days in Group B. Analysis of PSI among both groups shows that Group B, in whom Schanz pins technique was used, had significantly high rates of pin site infection (24.1%) compared to group A (9.6%) in whom K-wires technique was used (p 0.012).\u0000Conclusion: Our study concludes that the frequency of pin site infection is significantly less in Ilizarov fixator using K-wires (9.6%) as compared to Ilizarov fixator using Schanz pins(24.1%).","PeriodicalId":155428,"journal":{"name":"Clinical Medicine And Health Research Journal","volume":"102 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-11-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"117131341","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}