Journal of Clinical Imaging Science最新文献

{"title":"Adamantinoma-like Ewing sarcoma of the parotid gland: A case report.","authors":"Ayushi Vashishtha, Daniel Jeong, Hasanain Hasan, Rikesh J Makanji","doi":"10.25259/JCIS_142_2025","DOIUrl":"10.25259/JCIS_142_2025","url":null,"abstract":"<p><p>Adamantinoma-like Ewing sarcoma (ALES) of the parotid gland is an exceptionally rare neoplasm. We report the case of a 57-year-old male with a history of p16-positive tonsillar squamous cell carcinoma who presented 2 years after remission with excessive mucus production and neck stiffness. Imaging identified a left parotid mass, and diagnosis was confirmed through surgical pathology, with molecular testing revealing a Fused in Sarcoma-Fifth Ewing Variant (<i>FUS-FEV)</i> fusion gene. Treatment included radical parotidectomy, adjuvant external beam radiation, and systemic chemotherapy following the Ewing sarcoma paradigm. Despite initial response, the patient experienced significant toxicities and eventually succumbed to disease-related complications. This case illustrates the challenges in diagnosing and managing rare parotid malignancies and highlights the importance of multidisciplinary care.</p>","PeriodicalId":15512,"journal":{"name":"Journal of Clinical Imaging Science","volume":"15 ","pages":"47"},"PeriodicalIF":1.3,"publicationDate":"2025-12-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12860319/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146105594","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Multimodal imaging findings of primary inflammatory myofibroblastoma of the gallbladder in adolescents.","authors":"Xin-Ran Qu, Ying Yu, Guang-Bin Cui","doi":"10.25259/JCIS_145_2025","DOIUrl":"10.25259/JCIS_145_2025","url":null,"abstract":"<p><p>Inflammatory myofibroblastic tumor (IMT) is a rare mesenchymal-derived neoplasm that most commonly arises in the lung. It can also occur in other parts of the body. Primary IMT of the gallbladder is exceptionally uncommon. Due to the absence of large-sample studies, the current understanding of gallbladder IMT remains largely limited to case reports. This article reports the diagnosis and treatment course of a 13-year-old male with inflammatory myofibroblastoma of the gallbladder. It specifically focuses on delineating its distinct imaging characteristics across ultrasonography, computed tomography, and magnetic resonance imaging, aiming to enhance the accuracy of pre-operative diagnosis and provide valuable insights into the literature for this rare condition.</p>","PeriodicalId":15512,"journal":{"name":"Journal of Clinical Imaging Science","volume":"15 ","pages":"46"},"PeriodicalIF":1.3,"publicationDate":"2025-12-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12707596/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145774367","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"TFE3-rearranged renal cell car cinoma with massive calcification: Imaging-pathologic correlation.","authors":"Wenjuan Wang, Hao Ma, Wengang Wang, Dmytro Pylypenko","doi":"10.25259/JCIS_126_2025","DOIUrl":"10.25259/JCIS_126_2025","url":null,"abstract":"<p><p>Transcription Factor E3 (TFE3)-rearranged renal cell carcinoma (RCC) is rare. Radiologically, TFE3-rearranged RCC typically appears as a hyperattenuating mass with calcifications. Calcifications typically appear as small punctate or irregular coarse deposits, which are pathologically associated with granular and collagenous stromal degeneration. Here, we report a case of TFE3-rearranged RCC with extensive calcification in a young female, emphasizing imaging-pathologic correlation to enhance diagnostic accuracy. This case underscores the importance of recognizing atypical radiological features in rare RCC subtypes.</p>","PeriodicalId":15512,"journal":{"name":"Journal of Clinical Imaging Science","volume":"15 ","pages":"45"},"PeriodicalIF":1.3,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12707593/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145774439","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"An unusual case of breast cancer masked by hidradenitis suppurativa.","authors":"Sara Ramezanpour, Sai Swarupa Reddy Vulasala, Smita Sharma, Swati Sharma","doi":"10.25259/JCIS_43_2025","DOIUrl":"10.25259/JCIS_43_2025","url":null,"abstract":"<p><p>We report a rare case of a 28-year-old African-American woman with chronic hidradenitis suppurativa (HS), in whom breast masses were initially misattributed to HS-related inflammation, delaying diagnosis of breast cancer. She presented with back pain and diagnostic work-up revealed thoracic vertebral metastasis. Dedicated breast imaging showed suspicious breast masses and biopsy confirmed invasive ductal carcinoma. This case highlights the importance of breast imaging when inflammatory skin conditions of the breast fail to respond to standard treatment.</p>","PeriodicalId":15512,"journal":{"name":"Journal of Clinical Imaging Science","volume":"15 ","pages":"44"},"PeriodicalIF":1.1,"publicationDate":"2025-11-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12707591/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145774431","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Improving cone-beam computed tomography image quality for transarterial therapy of liver malignancies: Evaluation of a motion correction algorithm with and without automated bone removal.","authors":"Abdul Rehman Mustafa, Adham Khalil, Arun Kamireddy, Dana Angelina Schaar, Fereshteh Khorshidi, Izzet Altun, Heyuan Huang, Christopher R Bailey, Robert P Liddell, Nariman Nezami, Peter Fischer, Alexander Preuhs, Tina Ehtiati, Clifford R Weiss","doi":"10.25259/JCIS_150_2025","DOIUrl":"10.25259/JCIS_150_2025","url":null,"abstract":"<p><strong>Objectives: </strong>The objectives of the study are to compare the effect on image quality of a motion artifact correction algorithm (CAVAREC) alone versus in combination with an automated bone removal algorithm (ZIBOS) for motion-degraded intraprocedural liver cone-beam computed tomography (CBCT) images.</p><p><strong>Material and methods: </strong>In this retrospective, two-center, Institutional Review Board (IRB)-approved study, 48 CBCTs from 41 patients were included. Inclusion criteria were (a) age ≥18; (b) liver CBCT with contrast injected at the main, right, or left hepatic artery; and (c) CBCT motion-degraded. Exclusion criteria were (a) no visible tumor and (b) CBCT not capturing the entire liver. The mean (standard deviation [SD]) age was 64 (7) years, 81% male. 65% had hepatocellular carcinoma and 35% metastatic cancer. 69% CBCTs were from transarterial radioembolization (TARE) mapping, 25% transarterial chemoembolization, and 6% TARE treatment. Mean (SD) maximum tumor diameter was 4.6 (2.7) cm. CBCT images were processed with CAVAREC (prototype, Siemens Healthineers AG, Forchheim, Germany) and CAVAREC + ZIBOS (work in progress, Comprehenso, Hannover, Germany). Using CoroEval, sharpness for two segmental arteries per case was obtained quantitatively. Three blinded interventional radiologists independently evaluated overall image quality on a 0-100 scale and large vessels, small vessels, vessel sharpness, tumor feeders, tumor blush, and streak artifacts on a -50 to +50 scale relative to uncorrected images. Results were analyzed with paired <i>t-</i>tests and Wilcoxon signed-rank tests, adjusting <i>P</i>-values with the Benjamini-Hochberg procedure.</p><p><strong>Results: </strong>On quantitative assessment, mean (SD) sharpness for uncorrected, CAVAREC, and CAVAREC + ZIBOS (C+Z) images was 0.281 (0.04), 0.287 (0.04), and 0.284 (0.04), respectively, <i>P</i> = 0.02 for uncorrected versus CAVAREC and <i>P</i> > 0.05 for other comparisons. On qualitative assessment, mean (SD) overall quality for uncorrected, CAVAREC, and C+Z images was 45 (14), 53 (16), and 53 (17), respectively, <i>P</i> < 0.001 for both uncorrected versus CAVAREC and uncorrected versus C+Z and <i>P</i> = 0.06 for CAVAREC versus C+Z. The mean preference for both CAVAREC and C+Z compared to uncorrected images for all parameters ranged from +4.3 to +9.5, <i>P</i> < 0.001, except tumor blush which was +1.6 for CAVAREC and +0.9 for C+Z, <i>P</i> > 0.05. CAVAREC versus C+Z was not significant for any parameter.</p><p><strong>Conclusion: </strong>Motion artifact correction of liver CBCT images using CAVAREC improves image quality significantly. According to observer studies, integrating the automated bone segmentation algorithm ZIBOS with CAVAREC does not degrade image quality.</p>","PeriodicalId":15512,"journal":{"name":"Journal of Clinical Imaging Science","volume":"15 ","pages":"43"},"PeriodicalIF":1.3,"publicationDate":"2025-11-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12707598/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145774406","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparison of image quality in carotid dual-energy computed tomography angiography at 55 keV virtual monoenergetic imaging using deep learning and adaptive iterative reconstruction algorithm.","authors":"Xiaohan Liu, Chong Wang, Juan Long, Yang Wu, Zhongxiao Liu, Meng Yu, Chenzi Wang, Wenbei Xu, He Zhang, Aiyun Sun, Shuai Zhang, Kai Xu, Yankai Meng","doi":"10.25259/JCIS_109_2025","DOIUrl":"10.25259/JCIS_109_2025","url":null,"abstract":"<p><strong>Objectives: </strong>This study aims to evaluate the image quality of 55 keV virtual monoenergetic imaging (VMI) in carotid dual-energy computed tomography (CT) angiography (DE-CTA) reconstructed using deep learning image reconstruction (DLIR) algorithms and traditional iterative reconstruction algorithms.</p><p><strong>Material and methods: </strong>This prospective study included 48 patients who underwent DE-CTA examinations at our institution between December 2024 and January 2025. Image reconstructions were performed using 50% strength adaptive statistical iterative reconstruction-Veo (ASIR-V 50%), low and high strengths DLIR (DLIR-L and DLIR-H) algorithms. Objective image quality was evaluated by measuring background noise (standard deviation), signal-to-noise ratio (SNR), and contrast-to-noise ratio (CNR) at key anatomical locations, including the aortic arch, common carotid artery, carotid bifurcation, and internal carotid artery. Two senior radiologists conducted subjective assessments of image quality, focusing on image noise, artifacts, and vessel continuity, and the clarity of vascular wall margin.</p><p><strong>Results: </strong>Compared with ASIR-V 50% and DLIR-L, DLIR-H significantly improved image quality by reducing background noise and increasing SNR and CNR (<i>P</i> < 0.05). Subjectively, DLIR-H images demonstrated better suppression of noise and clearer vascular wall margin (<i>P</i> < 0.05). Subgroup analysis revealed that these improvements were more pronounced in patients with a body mass index (BMI) ≥24 kg/m². No significant differences were observed in CT attenuations among the three reconstruction methods (<i>P</i> > 0.05).</p><p><strong>Conclusion: </strong>At 55 keV VMI in carotid DE-CTA, DLIR-H significantly enhanced image quality, particularly by reducing noise and preserving fine anatomical structures. Its efficacy was especially notable in patients with BMI ≥24 kg/m².</p>","PeriodicalId":15512,"journal":{"name":"Journal of Clinical Imaging Science","volume":"15 ","pages":"42"},"PeriodicalIF":1.3,"publicationDate":"2025-11-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12707594/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145774398","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Malformations of cortical development on fetal MRI.","authors":"Shankar Srinivas Ganapathy, Kyle Hunter, Emily Janitz, Gayathri Sreedher","doi":"10.25259/JCIS_123_2023","DOIUrl":"10.25259/JCIS_123_2023","url":null,"abstract":"<p><p>Neuronal migrational anomalies, cortical dysplasias, hemimegalencephaly, and microcephalies are collectively termed malformations of cortical development (MCD). MCDs have multifactorial etiologies including genetic, environmental, vascular, and infectious insults between the late 1^st trimester and late 2^nd trimester. Neonatal correlates of various neuronal migration anomalies detected on fetal magnetic resonance imaging are illustrated. Physiologic immaturity of sulci and certain mimics of migration anomalies can pose a challenge, and these are also outlined.</p>","PeriodicalId":15512,"journal":{"name":"Journal of Clinical Imaging Science","volume":"15 ","pages":"41"},"PeriodicalIF":1.3,"publicationDate":"2025-11-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12596790/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145488485","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Incidentally detected retropharyngeal cystic parathyroid adenoma in trauma imaging: A diagnostic challenge.","authors":"Hunter Ryan Carlock, Sean Cleary, Shehanaz Ellika","doi":"10.25259/JCIS_89_2025","DOIUrl":"10.25259/JCIS_89_2025","url":null,"abstract":"<p><p>Computed tomography (CT) is often utilized for evaluation of patients presenting with traumatic injuries, and differentiating between traumatic and non-traumatic pathologies can be difficult, particularly for uncommon or atypically presenting disease. A 43-year-old male presented to the hospital as a restrained driver in a motor vehicle collision, and CT angiogram of the neck revealed a well-defined, mixed cystic and solid lesion, with enhancing components that were initially interpreted as a retropharyngeal hematoma with contained contrast extravasation. Serial laryngoscopes revealed stability of the lesion, and the mass was resected the following day without complication. Histopathology revealed this mass to be a cystic parathyroid adenoma. Diagnosis of a functional cystic parathyroid adenoma is difficult, and an atypical presentation like in our case is challenging to the radiologist when assessing trauma CTs. The typical findings of mixed solid and cystic component, intense enhancement of the solid component, and prominent inferior polar artery should increase suspicion for a cystic parathyroid adenoma. This case emphasizes the need for radiologists to maintain a broad differential diagnosis when reviewing trauma imaging, particularly in the head-and-neck region.</p>","PeriodicalId":15512,"journal":{"name":"Journal of Clinical Imaging Science","volume":"15 ","pages":"40"},"PeriodicalIF":1.3,"publicationDate":"2025-10-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12596788/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145488496","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Black bone magnetic resonance imaging in clinical practice: Systematic review of current perspectives and insights.","authors":"Dani N Jijo, Omkar Uttam Gaonkar, Mohit Kumar Pandey, V K Ilankathir, Anagha K A, Shashi Kumar Shetty","doi":"10.25259/JCIS_15_2025","DOIUrl":"10.25259/JCIS_15_2025","url":null,"abstract":"<p><p>Magnetic resonance imaging (MRI) has proven its strengths in soft-tissue imaging, but advancements in imaging techniques have now enhanced bone visualization. This review evaluates the effectiveness and reliability of black bone MRI for detecting and assessing bone abnormalities, particularly in orthopedic and craniofacial conditions. Articles from indexed journals such as Science Direct, Springer, Elsevier, PubMed/Medline, Wiley Online Library, and Scopus were analyzed, adhering to preferred reporting items for systematic review and meta-analysis guidelines. Ten studies met the criteria and were included in the study. The review highlights that black bone MRI outperforms computed tomography by offering superior imaging of bone and intracranial structures, leading to higher surgical accuracy and improved diagnostic precision.</p>","PeriodicalId":15512,"journal":{"name":"Journal of Clinical Imaging Science","volume":"15 ","pages":"39"},"PeriodicalIF":1.3,"publicationDate":"2025-10-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12530756/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145329521","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Whole-body magnetic resonance imaging with ultra-short echo time sequence versus fluorodeoxyglucose-positron emission tomography/computed tomography in detecting gynecologic metastases.","authors":"Kazim Ziya Gumus, Karina Hew, Savas Ozdemir, Sanjay Lamsal, Sindhu Kumar, Minh Nguyen, Pan Su, Vahid Khalilzad Sarghi, Mauricio Hernandez, Gregory C Wynn, Dheeraj Reddy Gopireddy, Chandana Lall","doi":"10.25259/JCIS_59_2025","DOIUrl":"10.25259/JCIS_59_2025","url":null,"abstract":"<p><strong>Objectives: </strong>This study aimed to assess the diagnostic performance of whole-body magnetic resonance imaging (wbMRI) in comparison with gold standard ¹⁸F-fluorodeoxyglucose-positron emission tomography/computed tomography (FDG-PET/CT) for detecting metastases in patients with gynecological cancer (GCa).</p><p><strong>Material and methods: </strong>We prospectively enrolled five histologically proven GCa patients who underwent FDG-PET/CT and were identified with metastatic disease in their lungs. We customized a wbMRI protocol including ultra-short echo time (UTE) MRI sequence with a stack-of-spiral acquisition and imaged the patients on a 3 Tesla MRI scanner. Nuclear medicine physicians and radiologists reviewed the PET/CT and MRI images respectively and compared the findings for each patient. PET/CT images were accepted gold standard. We calculated the sensitivities of wbMRI and assessed the differences in diagnostic performance between PET/CT and wbMRI using McNemar's test (<i>P</i> < 0.05).</p><p><strong>Results: </strong>Three patients had cervical cancer while two had ovarian cancer. FDG-PET/CT detected a total of 44 findings (including nodules, lesions, and lymph nodes) across the five patients. WbMRI showed 39 findings with a sensitivity of 89%. McNemar's test revealed no statistically significant difference between wbMRI and PET/CT. The pre-contrast UTE sequence displayed 33 findings (33/44) and in detecting lung nodules, it displayed an accuracy of 70% (7/10).</p><p><strong>Conclusion: </strong>This pilot study suggests that wbMRI demonstrates no statistically significant difference compared to ¹⁸FDG-PET/CT for detecting gynecological metastases. Furthermore, the UTE sequence proved valuable as part of the wbMRI protocol for detecting metastases without the need for a contrast agent.</p>","PeriodicalId":15512,"journal":{"name":"Journal of Clinical Imaging Science","volume":"15 ","pages":"38"},"PeriodicalIF":1.3,"publicationDate":"2025-10-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12530790/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145329448","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}