发布求助
文献互助 智能选刊 最新文献

Journal of Clinical Psychopharmacology最新文献

筛选
英文 中文
Examining Alternative Inclusion Criteria Based on Core Symptoms of Depression in Antidepressant Clinical Trials. 抗抑郁药临床试验中基于抑郁核心症状的替代纳入标准的研究
IF 2.9 3区 医学
Journal of Clinical Psychopharmacology Pub Date : 2025-01-01 Epub Date: 2024-11-18 DOI: 10.1097/JCP.0000000000001926
Evyn M Peters, Saba Aziz, Lloyd Balbuena
{"title":"Examining Alternative Inclusion Criteria Based on Core Symptoms of Depression in Antidepressant Clinical Trials.","authors":"Evyn M Peters, Saba Aziz, Lloyd Balbuena","doi":"10.1097/JCP.0000000000001926","DOIUrl":"10.1097/JCP.0000000000001926","url":null,"abstract":"","PeriodicalId":15455,"journal":{"name":"Journal of Clinical Psychopharmacology","volume":"45 1","pages":"46-47"},"PeriodicalIF":2.9,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142877231","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Broad-Spectrum Micronutrients or Antidepressants for Antenatal Depression: Effect on Maternal and Infant Birth Outcomes in an Observational Secondary Analysis of NUTRIMUM. 广谱微量营养素或抗抑郁药治疗产前抑郁症：NUTRIMUM观察性二级分析对母婴分娩结局的影响。
IF 2.9 3区 医学
Journal of Clinical Psychopharmacology Pub Date : 2025-01-01 Epub Date: 2024-12-02 DOI: 10.1097/JCP.0000000000001934
Jessica L Heaton, Siobhan A Campbell, Hayley A Bradley, Roger T Mulder, Lesley Dixon, Jacki Henderson, Julia J Rucklidge
{"title":"Broad-Spectrum Micronutrients or Antidepressants for Antenatal Depression: Effect on Maternal and Infant Birth Outcomes in an Observational Secondary Analysis of NUTRIMUM.","authors":"Jessica L Heaton, Siobhan A Campbell, Hayley A Bradley, Roger T Mulder, Lesley Dixon, Jacki Henderson, Julia J Rucklidge","doi":"10.1097/JCP.0000000000001934","DOIUrl":"10.1097/JCP.0000000000001934","url":null,"abstract":"<p><strong>Purpose/background: </strong>One-fifth of women experience antenatal depression. Untreated antenatal depression is associated with increased risk of adverse birth outcomes. This study investigated the effect of broad-spectrum micronutrients (BSM; vitamins and minerals), used to treat antenatal depression (NUTRIMUM trial), on birth outcomes.</p><p><strong>Methods/procedures: </strong>Birth outcomes of 129 mother-infant pairs were obtained from hospital medical records or personal health records for home births. Pairs from NUTRIMUM exposed to ≥8 weeks of BSM antenatally (MN; n = 55) were compared to pairs exposed to antidepressants antenatally (MED; n = 20) and a reference group (REF; n = 54) of pairs not exposed to trial BSM or antidepressants.</p><p><strong>Findings/results: </strong>Groups were comparable on demographic variables. At study entry, MN and MED had depression scores in the moderate range, statistically higher than REF (nonclinical range). MN and REF did not differ significantly for gestational age, preterm births, infant size, or infant resuscitation. There were significantly lower rates of postpartum hemorrhage in MN relative to REF (7.7% vs 30%; RR = 0.26, 95% CI [0.08-0.84]). Gestational age at birth was higher for MN (39.5 weeks) than MED (38.5 weeks; d = 0.67, 95% CI [0.15-1.20], P = 0.03) as well as infant birth length (52.2 vs 50.0 cm; d = 0.77, 95% CI [0.21-1.33], P = 0.02), and rates of infant resuscitation were lower (14.5% vs 45%; RR = 0.33, 95% CI [0.15-0.73]). Days of BSM exposure was positively associated with birth weight ( r = 0.32, P = 0.008) and length ( r = 0.25, P = 0.04).</p><p><strong>Implications/conclusions: </strong>Micronutrients used to alleviate antenatal depression may mitigate negative effects of depression on birth outcomes and showed more favorable birth outcomes compared with antidepressants.</p>","PeriodicalId":15455,"journal":{"name":"Journal of Clinical Psychopharmacology","volume":" ","pages":"4-15"},"PeriodicalIF":2.9,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142769466","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Citalopram Associated with the Development of Tinnitus in an Adolescent Girl: A Case Report. 西酞普兰与青春期女孩耳鸣的发展有关：一例报告。
IF 2.9 3区 医学
Journal of Clinical Psychopharmacology Pub Date : 2025-01-01 Epub Date: 2024-11-22 DOI: 10.1097/JCP.0000000000001937
Hasibe Ağır, Fatma Coşkun
{"title":"Citalopram Associated with the Development of Tinnitus in an Adolescent Girl: A Case Report.","authors":"Hasibe Ağır, Fatma Coşkun","doi":"10.1097/JCP.0000000000001937","DOIUrl":"10.1097/JCP.0000000000001937","url":null,"abstract":"","PeriodicalId":15455,"journal":{"name":"Journal of Clinical Psychopharmacology","volume":"45 1","pages":"57-58"},"PeriodicalIF":2.9,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142877229","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Recurrent Clozapine-Associated Pneumonia: A Case Report. 复发性氯氮平相关性肺炎1例报告。
IF 2.9 3区 医学
Journal of Clinical Psychopharmacology Pub Date : 2025-01-01 Epub Date: 2024-11-22 DOI: 10.1097/JCP.0000000000001942
Carolanne Wartman, Melodie Vick, Bethany Thomas
{"title":"Recurrent Clozapine-Associated Pneumonia: A Case Report.","authors":"Carolanne Wartman, Melodie Vick, Bethany Thomas","doi":"10.1097/JCP.0000000000001942","DOIUrl":"10.1097/JCP.0000000000001942","url":null,"abstract":"","PeriodicalId":15455,"journal":{"name":"Journal of Clinical Psychopharmacology","volume":"45 1","pages":"52-54"},"PeriodicalIF":2.9,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142877242","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Ischemic Priapism With Therapeutic Serum Concentrations of Psychotropic Medications. 血清中精神药物浓度达到治疗水平的缺血性尿崩症。
IF 2.9 3区 医学
Journal of Clinical Psychopharmacology Pub Date : 2025-01-01 Epub Date: 2024-11-27 DOI: 10.1097/JCP.0000000000001940
Fumiya Inoue, Yuji Okazaki, Kyungo Huh, Toshihisa Ichiba, Akira Namera
{"title":"Ischemic Priapism With Therapeutic Serum Concentrations of Psychotropic Medications.","authors":"Fumiya Inoue, Yuji Okazaki, Kyungo Huh, Toshihisa Ichiba, Akira Namera","doi":"10.1097/JCP.0000000000001940","DOIUrl":"10.1097/JCP.0000000000001940","url":null,"abstract":"","PeriodicalId":15455,"journal":{"name":"Journal of Clinical Psychopharmacology","volume":" ","pages":"54-55"},"PeriodicalIF":2.9,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142729112","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Noncardiac Chest Pain and Hypertensive Urgency During Long-term Intravenous Racemic Ketamine for Treatment-Resistant Depression. 长期静脉外消旋氯胺酮治疗难治性抑郁症期间的非心源性胸痛和高血压急症。
IF 2.9 3区 医学
Journal of Clinical Psychopharmacology Pub Date : 2025-01-01 Epub Date: 2024-11-18 DOI: 10.1097/JCP.0000000000001939
Liliana Patarroyo-Rodriguez, Jennifer L Vande Voort, Simon Kung, Sarah K Brown, Stefanie Cavalcanti, Matthew J Ritter, Balwinder Singh
{"title":"Noncardiac Chest Pain and Hypertensive Urgency During Long-term Intravenous Racemic Ketamine for Treatment-Resistant Depression.","authors":"Liliana Patarroyo-Rodriguez, Jennifer L Vande Voort, Simon Kung, Sarah K Brown, Stefanie Cavalcanti, Matthew J Ritter, Balwinder Singh","doi":"10.1097/JCP.0000000000001939","DOIUrl":"10.1097/JCP.0000000000001939","url":null,"abstract":"","PeriodicalId":15455,"journal":{"name":"Journal of Clinical Psychopharmacology","volume":"45 1","pages":"49-52"},"PeriodicalIF":2.9,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11745506/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142877234","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Treatment of Iatrogenic Anorgasmia in a Male Patient on Clozapine for Treatment-Resistant Schizophrenia: The Role of Pseudoephedrine. 治疗一名服用氯氮平治疗难治性精神分裂症的男性患者的先天性性高潮：伪麻黄碱的作用。
IF 2.9 3区 医学
Journal of Clinical Psychopharmacology Pub Date : 2025-01-01 Epub Date: 2024-11-12 DOI: 10.1097/JCP.0000000000001930
Paul O'Connell, Mohamed Alsaffar
{"title":"The Treatment of Iatrogenic Anorgasmia in a Male Patient on Clozapine for Treatment-Resistant Schizophrenia: The Role of Pseudoephedrine.","authors":"Paul O'Connell, Mohamed Alsaffar","doi":"10.1097/JCP.0000000000001930","DOIUrl":"10.1097/JCP.0000000000001930","url":null,"abstract":"","PeriodicalId":15455,"journal":{"name":"Journal of Clinical Psychopharmacology","volume":" ","pages":"55-57"},"PeriodicalIF":2.9,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142620493","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Recurrent Pancreatitis Associated With Atomoxetine Use in a 9-Year-Old Boy: A Case Report. 9岁男孩使用托莫西汀并发胰腺炎复发1例报告。
IF 2.9 3区 医学
Journal of Clinical Psychopharmacology Pub Date : 2025-01-01 Epub Date: 2024-11-29 DOI: 10.1097/JCP.0000000000001938
Ömer Faruk Bulut, Ali Karayağmurlu
{"title":"Recurrent Pancreatitis Associated With Atomoxetine Use in a 9-Year-Old Boy: A Case Report.","authors":"Ömer Faruk Bulut, Ali Karayağmurlu","doi":"10.1097/JCP.0000000000001938","DOIUrl":"10.1097/JCP.0000000000001938","url":null,"abstract":"","PeriodicalId":15455,"journal":{"name":"Journal of Clinical Psychopharmacology","volume":" ","pages":"48-49"},"PeriodicalIF":2.9,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142750456","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Ethics in Psychedelic Science: Promises and Responsibilities. 迷幻科学的伦理：承诺与责任。
IF 2.9 3区 医学
Journal of Clinical Psychopharmacology Pub Date : 2025-01-01 Epub Date: 2024-11-27 DOI: 10.1097/JCP.0000000000001944
Dominic Sisti
{"title":"Ethics in Psychedelic Science: Promises and Responsibilities.","authors":"Dominic Sisti","doi":"10.1097/JCP.0000000000001944","DOIUrl":"10.1097/JCP.0000000000001944","url":null,"abstract":"","PeriodicalId":15455,"journal":{"name":"Journal of Clinical Psychopharmacology","volume":" ","pages":"1-3"},"PeriodicalIF":2.9,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142729107","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Quality Assurance of Depression Ratings in Psychiatric Clinical Trials. 精神病学临床试验中抑郁评分的质量保证。
IF 2.9 3区 医学
Journal of Clinical Psychopharmacology Pub Date : 2025-01-01 Epub Date: 2024-11-21 DOI: 10.1097/JCP.0000000000001936
Michael T Sapko, Cortney Kolesar, Ian R Sharp, Jonathan C Javitt
{"title":"Quality Assurance of Depression Ratings in Psychiatric Clinical Trials.","authors":"Michael T Sapko, Cortney Kolesar, Ian R Sharp, Jonathan C Javitt","doi":"10.1097/JCP.0000000000001936","DOIUrl":"10.1097/JCP.0000000000001936","url":null,"abstract":"<p><strong>Background: </strong>Extensive experience with antidepressant clinical trials indicates that interrater reliability (IRR) must be maintained to achieve reliable clinical trial results. Contract research organizations have generally accepted 6 points of rating disparity between study site raters and central \"master raters\" as concordant, in part because of the personnel turnover and variability within many contract research organizations. We developed and tested an \"insourced\" model using a small, dedicated team of rater program managers (RPMs), to determine whether 3 points of disparity could successfully be demonstrated as a feasible standard for rating concordance.</p><p><strong>Methods: </strong>Site raters recorded and scored all Montgomery-Åsberg Depression Rating Scale (MADRS) interviews. Audio files were independently reviewed and scored by RPMs within 24 to 48 hours. Concordance was defined as the absolute difference in MADRS total score of 3 points or less. A MADRS total score that differed by 4 or more points triggered a discussion with the site rater and additional training, as needed.</p><p><strong>Results: </strong>In a sample of 236 ratings (58 patients), IRR between site ratings and blinded independent RPM ratings was 94.49% (223/236). The lowest concordance, 87.93%, occurred at visit 2, which was the baseline visit in the clinical trial. Concordance rates at visits 3, 4, 5, and 6 were 93.75%, 96.08%, 97.30%, and 100.00%, respectively. The absolute mean difference in MADRS rating pairs was 1.77 points (95% confidence interval: 1.58-1.95). The intraclass correlation was 0.984 and an η2 = 0.992 (F = 124.35, P < 0.0001).</p><p><strong>Conclusions: </strong>Rigorous rater training together with real-time monitoring of site raters by RPMs can achieve a high degree of IRR on the MADRS.</p>","PeriodicalId":15455,"journal":{"name":"Journal of Clinical Psychopharmacology","volume":"45 1","pages":"28-31"},"PeriodicalIF":2.9,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142877238","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
首页 上一页 下一页 尾页
0
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整，为了账户安全，请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
请完成安全验证×
相关产品
×
本文献相关产品
联系我们：info@booksci.cn Book学术提供免费学术资源搜索服务，方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号：481959085
Book学术官方微信