Putri Hendria Wardhani, Cita Rosita Sigit Prakoeswa, Muhammad Yulianto Listiawan
{"title":"Evaluation of Wrinkle and Dermal Thickness in the Forearm before and after Picosecond Laser Therapy.","authors":"Putri Hendria Wardhani, Cita Rosita Sigit Prakoeswa, Muhammad Yulianto Listiawan","doi":"10.4103/JCAS.JCAS_80_22","DOIUrl":"10.4103/JCAS.JCAS_80_22","url":null,"abstract":"<p><strong>Background: </strong>Skin wrinkles are generated as a result of the aging process. Dermal thickness underneath a wrinkle decreases absolutely. Approximately 20% of dermal thickness disappears as people become elderly. In recent times, people have attempted to reduce wrinkles using various procedures. Currently, available picosecond lasers in dermatology can create mechanical stress and the energy can be fractionated via diffractive lens arrays (DLA). An emerging indication for the picosecond laser includes photorejuvenation. Non-ablative laser skin rejuvenation therapy demonstrates the dermis can be safely reconstructed by only irradiating the skin surface with a laser. The clinical effects of picosecond pulse laser have been frequently reported, but few studies have included histological investigation.</p><p><strong>Aims and objectives: </strong>This study aimed to evaluate wrinkle and dermal thickness in the forearm before and after picosecond laser therapy.</p><p><strong>Materials and methods: </strong>Twenty healthy male and female subjects between 36 and 55 years old with wrinkles in the forearm who met the sample requirements and were willing to participate were recruited in this study. Clinical examination and biopsy for histopathological examination were carried out before and 4 weeks after therapy, then treatment was carried out using a picosecond laser.</p><p><strong>Results: </strong>At 1-month follow-up, a significant improvement was noted in wrinkle and dermal thickness (<i>P</i> < 0.05).</p><p><strong>Conclusions: </strong>This picosecond 755 nm alexandrite laser with DLA was found to be very effective in treating wrinkles, which was confirmed by a dermatologic assessment from forearm photographic assessment scaled and dermal thickness improvement.</p>","PeriodicalId":15415,"journal":{"name":"Journal of Cutaneous and Aesthetic Surgery","volume":"17 1","pages":"7-10"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11086935/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140911820","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A comparative study of fractional CO<sub>2</sub> laser with topical triamcinolone acetonide versus intralesional triamcinolone acetonide in the treatment of alopecia areata.","authors":"Harish Prasanna, Rajashekar Talari Srinivas, Suresh Kumar Kuppuswamy, Hanumanthayya Keloji, Pavithra Thotta Ravikumar","doi":"10.4103/JCAS.JCAS_31_23","DOIUrl":"10.4103/JCAS.JCAS_31_23","url":null,"abstract":"<p><strong>Introduction: </strong>Alopecia areata (AA) is a non-scarring alopecia of chronic autoimmune etiology with heterogenous severity against the anagen hair follicle over the scalp, beard, or any part of the body and is associated with a significant psychological morbidity in the mental status of the patients leading the patients to seek treatment for cosmetic reasons. The management of AA is very unpredictable and is associated with various cosmetic adverse effects. This study aimed at comparing the efficacy and safety of a novel procedure of laser-assisted drug delivery system of steroids with the first-line procedure of intralesional steroids (ILS) for the treatment of patchy AA.</p><p><strong>Aims and objectives: </strong>To assess and compare the efficacy and safety of fractional CO<sub>2</sub> laser in combination with topical triamcinolone acetonide aqueous solution and intralesional triamcinolone acetonide as a monotherapy and in the treatment of AA.</p><p><strong>Materials and methods: </strong>A total of 60 patchy AA patients were included in this study. Patients were randomized into two equal groups: Group A and Group B with 30 patients in each group using a computer-generated block randomization. Patients in Group A received fractional CO<sub>2</sub> laser with topical triamcinolone acetonide aqueous solution and Group B received ILS. Both groups received treatment for five settings with each setting a gap of 3 weeks. The efficacy and safety of treatment modalities in both groups were assessed using global photograph assessment (GPA)-scale, lesional area density score percentage of improvement (LAD score improvement %), visual discomfort scale (VDS), visual analogue scale, and documentation of adverse effects in each setting.</p><p><strong>Results: </strong>Efficacy of treatment modality-assessed using means score of GPA-scale and LAD score improvement % suggests quicker results to patients in Group B in initial settings but drastic improvement happens to patients in Group A in subsequent settings. At the end of 5th setting, GPA-scale and LAD score improvement % suggest maximum efficacy in patients in Group A and they are statistically significant (<i>P</i>-value < 0.001). The mean VDS in both groups suggests maximum discomfort in Group A, yet the patient satisfaction at the end of 5th setting was maximum with patients in Group A and they are statistically significant (<i>P</i>-value < 0.001). Cosmetic notable adverse effect of atrophy of skin was documented in 30% of patients in Group B.</p><p><strong>Conclusion: </strong>This study showed that fractional CO<sub>2</sub> laser with topical triamcinolone acetonide is a better treatment modality than the intralesional triamcinolone acetonide for the treatment of AA with respect to efficacy, safety, and adverse events.</p>","PeriodicalId":15415,"journal":{"name":"Journal of Cutaneous and Aesthetic Surgery","volume":"17 1","pages":"34-40"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11086937/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140911817","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Surgical pearl: Modified hypodermic needle and its cap for guarded prick incision.","authors":"Muhammed Mukhtar","doi":"10.4103/JCAS.JCAS_62_21","DOIUrl":"10.4103/JCAS.JCAS_62_21","url":null,"abstract":"<p><p>There are many instruments to prick the comedone before its extraction and scalp during hair transplantation. These instruments are not well guarded, and it can cause deep injury and fear in the patients. Here we described how to guard these needle for safety during procedure.</p>","PeriodicalId":15415,"journal":{"name":"Journal of Cutaneous and Aesthetic Surgery","volume":"17 1","pages":"66-68"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11086934/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140911824","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Alay S Banker, Bansri M Mahadevia, Harita Shah, Ahan A Banker
{"title":"Full Thickness Macular Hole in Aesthetician Occurring Due to Accidental Self-exposure to Cosmetic Laser Machine Trying to Take Special Precautions Against COVID-19.","authors":"Alay S Banker, Bansri M Mahadevia, Harita Shah, Ahan A Banker","doi":"10.4103/JCAS.JCAS_74_21","DOIUrl":"10.4103/JCAS.JCAS_74_21","url":null,"abstract":"<p><p>A 25-year-old aesthetician was operating Q-switch pulse (SPECTRA) cosmetic laser machine of 1,064 nm wavelength, for the purpose of skin bleaching. The probe suddenly slipped over the plastic sheet that had been placed to avoid COVID-19 exposure after which she complained of sudden loss of vision. She was diagnosed as having vitreous hemorrhage in her right eye and was treated conservatively for one month. She then complained of central scotoma and was diagnosed to have developed a full-thickness macular hole, for which she was advised vitrectomy surgery. The purpose of this case report is to emphasize the importance of taking precautions during the COVID-19 era and while doing that making sure how to handle the machines so as not to inflict any accidental injury to the operating physician. Macular Holes following skin bleaching with Nd:YAG laser occurring in operating aesthetician is rare as compared to that occurring in the patients.</p>","PeriodicalId":15415,"journal":{"name":"Journal of Cutaneous and Aesthetic Surgery","volume":"17 1","pages":"75-77"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11086931/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140911823","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Anaphylactic shock secondary to topical EMLA","authors":"V. M. V. Gowda, S. Shenoi, K. M. Augustine","doi":"10.4103/jcas.jcas_30_23","DOIUrl":"https://doi.org/10.4103/jcas.jcas_30_23","url":null,"abstract":"The eutectic mixture of local anesthetics (EMLAs) is an anesthetic cream frequently used by dermatologists for various aesthetic procedures on a daily basis. Although side effects of EMLA are usually mild local skin reactions, rare complications such as methemoglobinemia, central nervous system toxicity, and cardiotoxicity can occur. Herein, we are reporting a case of anaphylactic shock to topical application of EMLA.","PeriodicalId":15415,"journal":{"name":"Journal of Cutaneous and Aesthetic Surgery","volume":"127 13","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-11-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139197344","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Spontaneous and induced degradation of dermal fillers: A review","authors":"Uwe Wollina, A. Goldman","doi":"10.4103/jcas.jcas_137_23","DOIUrl":"https://doi.org/10.4103/jcas.jcas_137_23","url":null,"abstract":"Dermal fillers are among the most versatile tools in esthetic medicine. A broad range of temporary, semipermanent, and permanent filler products is on the market. We performed a narrative review on spontaneous and induced degradation of dermal fillers in vitro and in vivo. Hyaluronic acid-based fillers are the most frequently used temporary fillers. The products differ in their hyaluronic acid content, cross-linking, and rheological parameters. Endogenous hyaluronidase and reactive oxygen species are responsible for the spontaneous degradation of these fillers. Hyaluronidase digests the filler material by cleavage of the β-1,4 glycosidic linkage between N-acetyl-glucosamine and d-glucuronic acid. The enzyme can be used for treatment of medical and cosmetic adverse events due to hyaluronic acid-based filler. Higher hyaluronidase content and higher degree of cross-linking are major factors contributing to filler persistence over time. Semipermanent fillers are poly-(d),l-lactic acid and calcium hydroxylapatite. These filler types are decomposed by hydrolysis and osteoclastic enzymes. They usually persist up to 2 years, in single patients even more than 5 years. Sodium thiosulfate can stimulate degradation of calcium hydroxylapatite, but it is slow acting and not effective in case of emergency. Permanent fillers may show some kind of modification in situ, but spontaneous or induced degradation has not been documented. Once implanted the permanent fillers remain lifelong. Intralesional laser treatment supports the removal of permanent filler material as an alternative to surgery. Besides biocompatibility and toxicity, filler materials should also be assessed for degradation to improve patient safety.","PeriodicalId":15415,"journal":{"name":"Journal of Cutaneous and Aesthetic Surgery","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-11-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139201751","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Fatemeh Samiee-Rad, Fatemeh Ghasemi, Ensiyeh Bahadoran, M. Sofiabadi, Zahra Shalbaf, Armane Taherkhani, N. Gheibi
{"title":"The effect of topical 0.5% humic acid gel on male rats with skin ulcer","authors":"Fatemeh Samiee-Rad, Fatemeh Ghasemi, Ensiyeh Bahadoran, M. Sofiabadi, Zahra Shalbaf, Armane Taherkhani, N. Gheibi","doi":"10.4103/jcas.jcas_104_23","DOIUrl":"https://doi.org/10.4103/jcas.jcas_104_23","url":null,"abstract":"Humic derivatives have antibacterial and anti-inflammatory properties. This study aimed to assess the experimental wound-healing effect of 0.5% humic acid gel. A full-thickness skin wound was created on the dorsal side of 24 Sprague Dawley male rats (220–250g). The animals were then randomly divided into the control, sham, and experimental groups. Skin wounds were bandaged daily using sterile gauze dipped in normal saline, carboxymethylcellulose, and 0.5% humic acid for 21 days. The wound-healing rate was evaluated grossly and histologically at various time intervals post-injury. Wound-healing percentage was significantly higher in the gel treatment group at all time points (P < 0.05). The mean number of inflammatory cells was significantly lower in the humic acid gel group than in the other groups (P < 0.001). Moreover, the number of new vascular cells and fibroblasts were significantly increased in the humic acid gel compared to the control (P < 0.001). These data confirmed that 0.5% humic acid gel accelerates wound healing, probably by anti-inflammatory effects, as well as by promoting vascular and fibroblast proliferation. Therefore, the humic acid gel may be used to improve wound care.","PeriodicalId":15415,"journal":{"name":"Journal of Cutaneous and Aesthetic Surgery","volume":"380 ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-11-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139205011","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Custom-made dental prosthetic clip for postoperative management of earlobe keloids","authors":"Vikas Pathania, Rahul Udayasankar","doi":"10.4103/jcas.jcas_16_23","DOIUrl":"https://doi.org/10.4103/jcas.jcas_16_23","url":null,"abstract":"Earlobe keloids are a common condition with varied and cross-specialty presentation. The condition is often recalcitrant and difficult to treat on account of its location. Frequent recurrences following excision is often frustrating for the patient and the surgeon. Application of pressure along with intra-operative and postoperative intralesional steroids is a popular choice and is in vogue by surgeons and dermatologists. However, considering the uniqueness of the structure for every individual, it is often difficult to ensure one size fits all when using pressure therapy as an adjunct. We designed a simple PMMA dental prosthesis to ensure comfortable yet effective constant pressure over the lesion to ensure complete aesthetic outcome without recurrence in an operated earlobe keloid.","PeriodicalId":15415,"journal":{"name":"Journal of Cutaneous and Aesthetic Surgery","volume":"52 8","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-11-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139205142","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Pedunculated superficial angiomyxoma of the thigh mimicking molluscum pendulum","authors":"Abdulmooti Hawilo, Wejdene Fakhfakh, N. Litaiem","doi":"10.4103/jcas.jcas_72_23","DOIUrl":"https://doi.org/10.4103/jcas.jcas_72_23","url":null,"abstract":"Superficial angiomyxoma (SAM) is a rare acquired benign neoplasm. It may be sporadic or associated with Carney’s complex. Typical locations for SAM are the head, neck, and trunk. It usually presents as a skin-colored papule or sessile lobulated nodule. Large pedunculated forms are less common. We describe a sporadic massive pedunculated SAM of the thigh occurring in a 75-year-old man and provide a comprehensive summary of SAM characteristics.","PeriodicalId":15415,"journal":{"name":"Journal of Cutaneous and Aesthetic Surgery","volume":"47 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-11-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139202185","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Shubham Kumar, S. Patra, Bharti Devnani, Varun Rajagopalan, Maninder Kaur
{"title":"Giant neglected unresectable ulcerated basal cell carcinoma of face: Radiotherapy at rescue","authors":"Shubham Kumar, S. Patra, Bharti Devnani, Varun Rajagopalan, Maninder Kaur","doi":"10.4103/jcas.jcas_62_23","DOIUrl":"https://doi.org/10.4103/jcas.jcas_62_23","url":null,"abstract":"Basal cell carcinomas are typically considered indolent and slowly progressing tumors, but giant basal cell carcinomas are more aggressive with more risk of invasion and poor prognosis. management of such giant BCCs is difficult due to difficulty in surgical approach. we hereby reporting a case of giant ulcerated BCC of face treated with radiotherapy as a rescue treatment.","PeriodicalId":15415,"journal":{"name":"Journal of Cutaneous and Aesthetic Surgery","volume":"85 9","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-11-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139206662","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}