Hamad. M. Adress. Hasan, Huda S. Muftah, Nada. Hemdan. Ahmed
{"title":"Study the effect of some solvents on the λmax and absorbance of bromo phenol blue and phenol red indicators","authors":"Hamad. M. Adress. Hasan, Huda S. Muftah, Nada. Hemdan. Ahmed","doi":"10.36811/jca.2021.110034","DOIUrl":"https://doi.org/10.36811/jca.2021.110034","url":null,"abstract":"This study which carried out on some indicators including (Phenol red and Bromo phenol Blue). Different solvents were used including (Methanol, propanol, DMF and DMSO). The effect of solvents on the λ max and absorbance values were investigated. The results recorded that the λmax values were effected and changed according to the polarities of the applied solvents. Also, the obtained results showed changes in the absorbance values after applied solvents compared with the original absorbance values.\u0000\u0000Keywords: Bromophenol blue; Phenol red; Effect of solvents on electronic transitions","PeriodicalId":15265,"journal":{"name":"Journal of Chemistry and Applications","volume":"7 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-12-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78491086","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"In vitro antimicrobial activity screening of new Heterocyclic compounds derived from 5-bromo-2,3-di(furan-2-yl)-1h-indole","authors":"H. A. A. Mageed, Reda F. El-Ezabi, F. Khaled","doi":"10.36811/jca.2021.110033","DOIUrl":"https://doi.org/10.36811/jca.2021.110033","url":null,"abstract":"This article describes the antimicrobial activity evaluation of new heterocyclic compounds derived from 5-bromo-2,3-di(furan-2-yl)-1h-indole. Heterocyclic moiety serve as perfect framework on which pharmacophores can be effectively attached to produce novel drugs. New compounds were obtained on the basis of derivatives including 1H-indole-2,3-dione derivatives. Acid-catalyzed, three-component reaction (Belinelli synthesis) between 5-bromo-2,3-di(furan-2-yl)1H-indole, acetylacetone and semi carbazide, thiosemicarbazone, urea, thiourea, guanidine constitutes a rapid and facile synthesis of corresponding tetrahydro pyrimidines, which are interesting compounds with a potential for pharmaceutical application. Antimicrobial tests revealed high antibacterial activity of obtained derivatives. The synthesized compounds have been screened for their in vitro antimicrobial activity against various strains of bacteria and fungi.\u0000\u0000Keywords: Vitro; Heterocyclic Compounds; Antimicrobial","PeriodicalId":15265,"journal":{"name":"Journal of Chemistry and Applications","volume":"93 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-12-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83825000","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Estimate Lead and Cadmium contents of some archeological samples collected from ancient cities location (Cyrene and Abolonia) at Al - Gabal Al -Akhder Region, Libya","authors":"Hamad. M. Adress. Hasan","doi":"10.36811/jca.2021.110035","DOIUrl":"https://doi.org/10.36811/jca.2021.110035","url":null,"abstract":"This study was carried out on archeological samples which collected from one of the most important ancient cities which located at eastern north side of Libya, these cities called (Cyrene and Abolonia Cyrene). Different samples were collected from the outside surface of the studied samples. The contents of lead (pb) and cadmium (Cd) were determined b using atomic absorption instrument. The results showed small variations for the studied metals between the studied samples. The concluded that the source of the detected metals are mainly due to the effects of air pollutions by the dust of machines and cars.","PeriodicalId":15265,"journal":{"name":"Journal of Chemistry and Applications","volume":"89 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-12-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83869301","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Eman, G. A. Allafi, Om-alsaad E. I. Omar, Fayrouz A. Khaled
{"title":"Effect of Tramadol on Hormones and Lipid Peroxidation of male Rabbits","authors":"Eman, G. A. Allafi, Om-alsaad E. I. Omar, Fayrouz A. Khaled","doi":"10.36811/jca.2021.110036","DOIUrl":"https://doi.org/10.36811/jca.2021.110036","url":null,"abstract":"Tramadol manhandle straightforwardly impacts the discharge of luteinizing hormone and follicular stimulating g hormone from the front pituitary organ that diminishes the common discharge of luteinizing hormone in a pulsatile way, resulting in a negative impact on male testiclesdue to lower levels of testosterone hormone. Animals were orally given 40 mg/kg B.W. doses of tramadol. The tried measurements were given to rabbits each other day for 6 weeks. Tramadol significantly decreased body weight (BW), weight of brain, testes, testosterone, estradiol, follicle stimulating hormone (FSH), luteinizing hormone (LH), triiodothyronine (T3) and thyroxin hormone (T4). While, it caused significant increase in thiobarbituric acid-reactive substances (TBARS) concentrations in plasma, testes and brain.\u0000\u0000Keywords: Tramadol; Hormone; TBARS; Rabbits","PeriodicalId":15265,"journal":{"name":"Journal of Chemistry and Applications","volume":"22 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-12-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82241023","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Kareima A. Abdelghani, Nisrin, F. Kirallah, Saleh M. Bofarwa, A A Idress
{"title":"Corrosion protection of mild steel in Hydrochloric acid solutions using expired Hydrocortisone sodium succinate drug","authors":"Kareima A. Abdelghani, Nisrin, F. Kirallah, Saleh M. Bofarwa, A A Idress","doi":"10.36811/jca.2021.110031","DOIUrl":"https://doi.org/10.36811/jca.2021.110031","url":null,"abstract":"The erosion hindrance of carbon steel in 1M HCl in nearness and nonappearance of terminated Hydrocortisone Sodium Succinate has been examined utilizing mass-loss. Comes about gotten appeared that the restraint productivity expanded with the increment of the concentration of the utilized medicate and diminished with the increment of temperature. The adsorption of this sedate on carbon steel surface takes after Langmuir’s adsorption isotherm. A few thermodynamic parameters were calculated. The motor parameters of erosion of carbon steel in HCl arrangement have been examined.\u0000Keywords: Corrosion inhibition; Carbon steel; Hydrocortisone","PeriodicalId":15265,"journal":{"name":"Journal of Chemistry and Applications","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-11-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89792860","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"T Cell Engineering as Therapy for Cancer and HIV","authors":"Elena Locci, Silvia Raymond","doi":"10.36811/jca.2021.110027","DOIUrl":"https://doi.org/10.36811/jca.2021.110027","url":null,"abstract":"Through T-cell engineering, researchers at the California South University (CSU) Cancer Research Institute (CRI) have shown that tumor growth can be stopped in a variety of cancers and prevented from spreading to other tissues. Findings from this study are the result of decades of research by Professor Alireza Heidari, a member of the Cancer Biology Research Program at the California South University (CSU), who discovered a protein called AH that can inhibit the growth and spread of cancer cells in several different ways. They become in the tissues of the body.\u0000\u0000Keywords: Cancer; Cells; Tissues, Tumors; Prevention, Prognosis; Diagnosis; Imaging; Screening; Treatment; Management","PeriodicalId":15265,"journal":{"name":"Journal of Chemistry and Applications","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-11-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79891677","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Differential Diagnosis of Benign and Malignant Breast Masses Using Diffusion-Weighted Magnetic Resonance Imaging (MRI)","authors":"Alireza Heidari, E. Locci, Silvia Raymond","doi":"10.36811/jca.2021.110022","DOIUrl":"https://doi.org/10.36811/jca.2021.110022","url":null,"abstract":"When it comes to the microbiome, people usually think of the gut, but there is also the breast microbiome, and its role in the health and risk of breast cancer is not fully understood. A microbiome is a collection of microorganisms that live in a specific environment in the body. Diet can affect the breast microbiome, which shows that like the gut microbiome, breast microbiomes can respond to diet. New research now shows that diet, including fish oil supplements, can alter not only the breast microbiome but also its cancerous tumors.\u0000\u0000Keywords: Cancer; Cells; Tissues, Tumors; Prevention, Prognosis; Diagnosis; Imaging; Screening; Treatment; Management","PeriodicalId":15265,"journal":{"name":"Journal of Chemistry and Applications","volume":"73 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-11-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82290305","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A Comparison of Flow Cytometry, Bone Marrow Biopsy and Bone Marrow Aspirates in the Detection of Lymphoid Infiltration in T Cell Disorders","authors":"Elena Locci, Silvia Raymond","doi":"10.36811/jca.2021.110026","DOIUrl":"https://doi.org/10.36811/jca.2021.110026","url":null,"abstract":"Leukemia occurs when a person's entire bone marrow tissue space is occupied by cancer cells or blasts that are young, dysfunctional, undifferentiated, and proliferating cells. In this situation, there is no space left for the bone marrow to be able to produce normal blood cells such as platelets, red and white blood cells. These patients suffer from severe bleeding due to decreased platelets or due to a decrease in white blood cells, which are often diagnosed with dangerous infections that cause death in these patients. The exact cause of leukemias is not yet known, but a number of factors have been identified that play a role in the development of these cancers, including high doses of radiation or atomic radiation, prolonged exposure to certain chemicals, and some Mentioned viruses and some genetic diseases such as Down syndrome or underlying diseases.\u0000\u0000Keywords: Cancer; Cells; Tissues, Tumors; Prevention, Prognosis; Diagnosis; Imaging; Screening; Treatment; Management","PeriodicalId":15265,"journal":{"name":"Journal of Chemistry and Applications","volume":"82 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-11-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81009208","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Engineering T-Cell Activation for Immunotherapy by Mechanical Forces","authors":"Elena Locci, Silvia Raymond","doi":"10.36811/jca.2021.110023","DOIUrl":"https://doi.org/10.36811/jca.2021.110023","url":null,"abstract":"A groundbreaking study led by engineering and medical researchers at the California South University (CSU) shows how immune cells engineered in new cancer therapies can overcome physical barriers so that the patient's own immune system can fight tumors. This research could improve the future of millions of cancer patients worldwide. Immunotherapy, instead of using chemicals or radiation, is a type of cancer treatment that helps the patient's immune system fight cancer. T cells are a type of white blood cell that is essential for the body's immune system. Cytotoxic T cells are like soldiers searching for and destroying target invading cells. Although there has been success in using immunotherapy for some types of cancer in the blood or blood-producing organs, T cell work is much more difficult in solid tumors.\u0000\u0000Keywords: Cancer; Cells; Tissues, Tumors; Prevention, Prognosis; Diagnosis; Imaging; Screening; Treatment; Management","PeriodicalId":15265,"journal":{"name":"Journal of Chemistry and Applications","volume":"16 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-11-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87027612","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Therapeutic Potential of Pharmacological Targeting NLRP3 Inflammasome Complex in Cancer Using Inhibition of NLRP3 Inflammasome in Tumor Microenvironment Leads to Suppression of Metastatic Potential of Cancer Cells","authors":"Elena Locci, Silvia Raymond","doi":"10.36811/jca.2021.110030","DOIUrl":"https://doi.org/10.36811/jca.2021.110030","url":null,"abstract":"Thanks to work by researchers at the California South University (CSU) Cancer Research Institute (CRI), they may soon have new tools to treat melanoma and other cancers. In an article published last month, members of the Cancer Research Institute (CRI) introduced an intracellular complex. Involved in melanoma-mediated inflammation and leads to tumor growth and progression. The researchers found that by inhibiting NLRP3, they could reduce inflammation and tumor spread.\u0000\u0000Keywords: Cancer; Cells; Tissues, Tumors; Prevention, Prognosis; Diagnosis; Imaging; Screening; Treatment; Management","PeriodicalId":15265,"journal":{"name":"Journal of Chemistry and Applications","volume":"40 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-11-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79182261","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}