A Comparison of Flow Cytometry, Bone Marrow Biopsy and Bone Marrow Aspirates in the Detection of Lymphoid Infiltration in T Cell Disorders

Abstract

Leukemia occurs when a person's entire bone marrow tissue space is occupied by cancer cells or blasts that are young, dysfunctional, undifferentiated, and proliferating cells. In this situation, there is no space left for the bone marrow to be able to produce normal blood cells such as platelets, red and white blood cells. These patients suffer from severe bleeding due to decreased platelets or due to a decrease in white blood cells, which are often diagnosed with dangerous infections that cause death in these patients. The exact cause of leukemias is not yet known, but a number of factors have been identified that play a role in the development of these cancers, including high doses of radiation or atomic radiation, prolonged exposure to certain chemicals, and some Mentioned viruses and some genetic diseases such as Down syndrome or underlying diseases. Keywords: Cancer; Cells; Tissues, Tumors; Prevention, Prognosis; Diagnosis; Imaging; Screening; Treatment; Management