{"title":"利用肿瘤微环境中NLRP3炎性体的抑制抑制癌细胞的转移潜能，靶向NLRP3炎性体复合物的药物治疗潜力","authors":"Elena Locci, Silvia Raymond","doi":"10.36811/jca.2021.110030","DOIUrl":null,"url":null,"abstract":"Thanks to work by researchers at the California South University (CSU) Cancer Research Institute (CRI), they may soon have new tools to treat melanoma and other cancers. In an article published last month, members of the Cancer Research Institute (CRI) introduced an intracellular complex. Involved in melanoma-mediated inflammation and leads to tumor growth and progression. The researchers found that by inhibiting NLRP3, they could reduce inflammation and tumor spread.\n\nKeywords: Cancer; Cells; Tissues, Tumors; Prevention, Prognosis; Diagnosis; Imaging; Screening; Treatment; Management","PeriodicalId":15265,"journal":{"name":"Journal of Chemistry and Applications","volume":"40 1","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2021-11-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"1","resultStr":"{\"title\":\"Therapeutic Potential of Pharmacological Targeting NLRP3 Inflammasome Complex in Cancer Using Inhibition of NLRP3 Inflammasome in Tumor Microenvironment Leads to Suppression of Metastatic Potential of Cancer Cells\",\"authors\":\"Elena Locci, Silvia Raymond\",\"doi\":\"10.36811/jca.2021.110030\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Thanks to work by researchers at the California South University (CSU) Cancer Research Institute (CRI), they may soon have new tools to treat melanoma and other cancers. In an article published last month, members of the Cancer Research Institute (CRI) introduced an intracellular complex. Involved in melanoma-mediated inflammation and leads to tumor growth and progression. The researchers found that by inhibiting NLRP3, they could reduce inflammation and tumor spread.\\n\\nKeywords: Cancer; Cells; Tissues, Tumors; Prevention, Prognosis; Diagnosis; Imaging; Screening; Treatment; Management\",\"PeriodicalId\":15265,\"journal\":{\"name\":\"Journal of Chemistry and Applications\",\"volume\":\"40 1\",\"pages\":\"\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2021-11-11\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"1\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of Chemistry and Applications\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.36811/jca.2021.110030\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Chemistry and Applications","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.36811/jca.2021.110030","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Therapeutic Potential of Pharmacological Targeting NLRP3 Inflammasome Complex in Cancer Using Inhibition of NLRP3 Inflammasome in Tumor Microenvironment Leads to Suppression of Metastatic Potential of Cancer Cells
Thanks to work by researchers at the California South University (CSU) Cancer Research Institute (CRI), they may soon have new tools to treat melanoma and other cancers. In an article published last month, members of the Cancer Research Institute (CRI) introduced an intracellular complex. Involved in melanoma-mediated inflammation and leads to tumor growth and progression. The researchers found that by inhibiting NLRP3, they could reduce inflammation and tumor spread.
Keywords: Cancer; Cells; Tissues, Tumors; Prevention, Prognosis; Diagnosis; Imaging; Screening; Treatment; Management
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