Therapeutic Potential of Pharmacological Targeting NLRP3 Inflammasome Complex in Cancer Using Inhibition of NLRP3 Inflammasome in Tumor Microenvironment Leads to Suppression of Metastatic Potential of Cancer Cells

Elena Locci, Silvia Raymond
{"title":"Therapeutic Potential of Pharmacological Targeting NLRP3 Inflammasome Complex in Cancer Using Inhibition of NLRP3 Inflammasome in Tumor Microenvironment Leads to Suppression of Metastatic Potential of Cancer Cells","authors":"Elena Locci, Silvia Raymond","doi":"10.36811/jca.2021.110030","DOIUrl":null,"url":null,"abstract":"Thanks to work by researchers at the California South University (CSU) Cancer Research Institute (CRI), they may soon have new tools to treat melanoma and other cancers. In an article published last month, members of the Cancer Research Institute (CRI) introduced an intracellular complex. Involved in melanoma-mediated inflammation and leads to tumor growth and progression. The researchers found that by inhibiting NLRP3, they could reduce inflammation and tumor spread.\n\nKeywords: Cancer; Cells; Tissues, Tumors; Prevention, Prognosis; Diagnosis; Imaging; Screening; Treatment; Management","PeriodicalId":15265,"journal":{"name":"Journal of Chemistry and Applications","volume":"40 1","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2021-11-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"1","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Chemistry and Applications","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.36811/jca.2021.110030","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 1

Abstract

Thanks to work by researchers at the California South University (CSU) Cancer Research Institute (CRI), they may soon have new tools to treat melanoma and other cancers. In an article published last month, members of the Cancer Research Institute (CRI) introduced an intracellular complex. Involved in melanoma-mediated inflammation and leads to tumor growth and progression. The researchers found that by inhibiting NLRP3, they could reduce inflammation and tumor spread. Keywords: Cancer; Cells; Tissues, Tumors; Prevention, Prognosis; Diagnosis; Imaging; Screening; Treatment; Management
利用肿瘤微环境中NLRP3炎性体的抑制抑制癌细胞的转移潜能,靶向NLRP3炎性体复合物的药物治疗潜力
多亏了南加州大学癌症研究所(CRI)的研究人员的工作,他们可能很快就会有治疗黑色素瘤和其他癌症的新工具。在上个月发表的一篇文章中,癌症研究所(CRI)的成员介绍了一种细胞内复合物。参与黑色素瘤介导的炎症并导致肿瘤的生长和进展。研究人员发现,通过抑制NLRP3,他们可以减少炎症和肿瘤扩散。关键词:癌症;细胞;组织,肿瘤;预防、预测;诊断;成像;筛选;治疗;管理
本文章由计算机程序翻译,如有差异,请以英文原文为准。
求助全文
约1分钟内获得全文 求助全文
来源期刊
自引率
0.00%
发文量
0
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:604180095
Book学术官方微信