Journal of Biology and Life Science最新文献

{"title":"Role of Sonography in the Assessment of Dengue Fever with Serological Correlation","authors":"Amir Rashid, Amer Fakhr, Abdul Rehman Azeem, Abdul Rehman Arshad, Waqas Ahmed, Yastoor Ahmed","doi":"10.37185/lns.1.1.390","DOIUrl":"https://doi.org/10.37185/lns.1.1.390","url":null,"abstract":"Objective: To assess ultrasound findings and their correlation with hematological parameters in patients with serologically confirmed Dengue Fever (DF).Study Design: Cross-sectional study.Place and Duration of Study: The study was carried out at the Department of Medicine of Pak Emirates Military Hospital (PEMH), Rawalpindi, Pakistan from April 2022 to July 2022.Methods: All participants in this study were serologically confirmed to have dengue disease. Each participant underwent chest, abdomen, and pelvis ultrasound examinations and a complete blood count (CBC). Both descriptive and analytic factors were analyzed statistically. Chi-Square / Fisher exact tests were employed to determine the connection between variables. A p-value less than (0.05) was statistically significant.Results: 166 individuals with Dengue NS-1 antigen positive with a mean age of 35.77±11.13 years were included in this research. The mean duration of symptoms at the time of admission was 7.32± 1.86 days, and the average duration of hospital stay was 6.69± 2.01 days. Edema of the gallbladder wall was noticed in 67 (40.36%) of patients, whereas hepatomegaly was observed in 82 (49.39%). Ascites in 49 (29.51%), Pleural effusion in 48 (28.91%), and splenomegaly in 37 (22.28%). The average count of megakaryocytes was 97.09± 43.10. Significantly more sonographic anomalies were identified in patients younger than 36 years of age.Conclusion: Ultrasound helps in early detection of leaky phase and complications in serologically confirmed patients with Dengue Fever who need prompt medical care.
 How to cite this: Rashid A, Fakhr A, Azeem AR, Arshad AR, Ahmed W, Ahmed Y. Role of Sonography in the Assessment of Dengue Fever with Serological Correlation. Life and Science. 2023; 4(4): 410-414. doi: http://doi.org/10.37185/LnS.1.1.390","PeriodicalId":15254,"journal":{"name":"Journal of Biology and Life Science","volume":"57 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135547395","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Diagnostic Accuracy of Cord Blood Bilirubin in Predicting Neonatal Hyperbilirubinemia, Taking Neonatal Hyperbilirubinemia within One Week of Birth as Gold Standard","authors":"Maryam Majeed, Daniyal Ahmed, Danish Hanif, Hamna Khaliq, Ali Ahmad, Zunaira Asghar Awan","doi":"10.37185/lns.1.1.347","DOIUrl":"https://doi.org/10.37185/lns.1.1.347","url":null,"abstract":"Objective: To determine the diagnostic accuracy of cord blood bilirubin in predicting neonatalhyperbilirubinemia, taking neonatal hyperbilirubinemia within one week of birth as the gold standard.Study Design: Across-sectional study.Place and Duration of Study: The Study was conducted at the Department of Pediatric Medicine, Sheikh Zayed Hospital, Rahim Yar Khan, Pakistan from 7 September 2020 to 6 March 2021.Methods: A total of 366 term neonates of both gendersgenders were included. Neonates with congenital hypothyroidism, neonatal hepatitis, biliary atresia, and sepsis were excluded. After getting informed consent from parents, a cord blood sample was taken and sent to the institutional laboratory for measuring total bilirubin levels, and neonatal hyperbilirubinemia (yes/no) was noted. All neonates were followed by the researcher for one week and neonatal hyperbilirubinemia was noted.Results: The study yielded 193 true positive and 14 false positive cases, along with 7 false negative and 152 true negative cases, with a statistically significant p-value of 0.0001. Overall, the diagnostic accuracy of cord blood bilirubin in predicting neonatal hyperbilirubinemia, using neonatal hyperbilirubinemia within one week of birth as the gold standard, was found to be 96.50% for sensitivity, 91.57% for specificity, 93.24% for positive predictive value, 95.60% for negative predictive value, and 94.26% for diagnostic accuracy.Conclusion: This study has shown that cord blood bilirubin has a rather good diagnostic accuracy for predicting newborn hyperbilirubinemia.
 How to cite this: Majeed M, Ahmed D, Hanif D, Khaliq H, Ahmad A, Khan ZA. Diagnostic Accuracy of Cord Blood Bilirubin in Predicting Neonatal Hyperbilirubinemia, Taking Neonatal Hyperbilirubinemia within One Week of Birth as Gold Standard. Life and Science. 2023; 4(4): 401-409. doi: http://doi.org/10.37185/LnS.1.1.347","PeriodicalId":15254,"journal":{"name":"Journal of Biology and Life Science","volume":"32 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135547503","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Occurrences of Dental Diseases in Dogs in a Teaching Animal Hospital, Morogoro, Tanzania","authors":"Immanuel Justine, Modesta Makungu","doi":"10.5296/jbls.v15i1.20859","DOIUrl":"https://doi.org/10.5296/jbls.v15i1.20859","url":null,"abstract":"Dental diseases are common in dogs with a prevalence of more than 80% in some breeds of dogs. They cause damage to oral health and may act as a source of bacteria causing other diseases such as endocarditis, pneumonia and arthritis. A cross section study was conducted to determine the current status on the occurrence of dental diseases in dogs attended at Sokoine University of Agriculture (SUA) Teaching Animal Hospital in Morogoro, Tanzania. A total of 87 dogs were examined macroscopically for the presence of dental diseases. Dogs examined in this study ranged from medium (93.1%) to large (6.9%) sized, and up to 73.6% were mixed-breed. The minimum and maximum ages of the dogs were 6 and 72 months, respectively, with majority being females (60.9%). The proportions of intact, spayed and castrated were 92%, 5.8% and 2.3%, respectively. Of the 87 dogs examined, 62.1% had different kinds of dental diseases. The frequently observed dental diseases were; dental deposits (43.7%), missing teeth (24.1%), periodontal disease (20.7%), dental attrition (16.1%), and dental abrasion (10.3%). Further, it was noted that none of the dogs had been previous underwent routine dental check-up or anaesthetised for dental cleaning. This study indicates that dental diseases are frequent in dogs attended at SUA Teaching Animal Hospital. Therefore, it is recommended that routine dental examination should be performed in dogs presented at the Teaching Animal Hospital. Further, there is a need for educating dog breeders and owners on the importance of dental home care.","PeriodicalId":15254,"journal":{"name":"Journal of Biology and Life Science","volume":"15 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135258400","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Reviewer Acknowledgements for Journal of Biology and Life Scienc, Vol. 14, No. 2","authors":"Kelvin Lee","doi":"10.5296/jbls.v14i2.21270","DOIUrl":"https://doi.org/10.5296/jbls.v14i2.21270","url":null,"abstract":"Journal of Biology and Life Science (JBLS) would like to acknowledge the following reviewers for their assistance with peer review of manuscripts for this issue. Many authors, regardless of whether JBLS publishes their work, appreciate the helpful feedback provided by the reviewers. Their comments and suggestions were of great help to the authors in improving the quality of their papers. Each of the reviewers listed below returned at least one review for this issue.Reviewers for Volume 14, Number 2Bratko Filipic, CIETO, SloveniaHoe Yin Chen, Tunku Abdul Rahman University College, MalaysiaHomyra Tasnim, Louisiana State University, BangladeshHui Xiang, Allergan, Inc., USAMemoona Ramzan, University of Miami, USAMohammad Tavakkoli Yaraki, National University of Singapore, SingaporeNatalia Tkachuk, T.H. Shevchenko National University “Chernihiv Colehium”, UkraineRajaa Ahmed Mahmoud, University of Basrah, Iraq Kelvin LeeEditorial AssistantJournal of Biology and Life Science-------------------------------------------Macrothink Institute5348 Vegas Dr.#825Las Vegas, Nevada 89108United StatesTel: 1-702-953-1852 ext.510Fax: 1-702-420-2900E-mail 1: jbls@macrothink.orgE-mail 2: jbls@macrothink.comURL: http://jbls.macrothink.org","PeriodicalId":15254,"journal":{"name":"Journal of Biology and Life Science","volume":"34 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-07-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135313712","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Frequency of Raised Serum Uric Acid in Patients with Stroke; A Cross-Sectional Study","authors":"R. Kousar, Mirza Sijeel Ahmad, Robina Kousar, Sobia Latif, Anam Zargham, A. Khan","doi":"10.37185/lns.1.1.321","DOIUrl":"https://doi.org/10.37185/lns.1.1.321","url":null,"abstract":"Objective: To define the rate of raised serum uric acid in patients with Stroke.Study Design: Cross-sectional study.Place and Duration of study: The study was carried out in the Department of Medicine, Military Hospital, Rawalpindi, Pakistan, from 13th July 2017 to 12th January 2018.Materials and Methods: A total of 96 cases of ischemic Stroke aged 26-74 years were selected. Cases with hemorrhagic Stroke who were consuming anti-hyperuricemia medications, diuretics, and Gout were excluded. Patients who fulfilled the clinical or radiological diagnostic criteria of Stroke underwent laboratory tests which included serum uric acid levels, fasting lipid profile, 24hrs urine for creatinine clearance and proteinuria, blood sugar levels, and renal profile.Results:   Among 96 patients from 26 to 74 years of age, with a mean of 54.01 ± 12.42 years. Fifty six cases (58.33%) were from 51 to 74 years of age, 48 (50.0%) were male, and 48 (50.0%) were females. Hyperuricemia was found in 55 (57.29%) patients, whereas there was no Hyperuricemia in 41 (42.71%) patients. Conclusion: The rate of raised serum uric acid is high in patients with Stroke.","PeriodicalId":15254,"journal":{"name":"Journal of Biology and Life Science","volume":"13 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-07-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90186219","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prevalence of Mediterranean Mutation of Glucose 6 Phosphate Dehydrogenase in Children of Malak Din Khel Subtribe of Afridi","authors":"Mohammad Amjid, Nazish Farooq","doi":"10.37185/lns.1.1.403","DOIUrl":"https://doi.org/10.37185/lns.1.1.403","url":null,"abstract":"Objective: To determine the prevalence of Glucose 6 Phosphate Dehydrogenase (G6PD) deficiency in the Malak Din Khel subtribe, the biggest subtribe of Afridi, with expectations of newer findings in the area of medicine and research.Study Design: Cross-sectional study.Place and Duration of Study: This study was conducted in District Khyber from March 2018 to August 2018.Materials and Methods: The sample size of this study was 177 preschool-going children of 4-5 years of age. Multistage cluster sampling was done. Only resident families of Khyber Agency were selected. Children of age 04 to 05 years were enrolled in the study after consent from a parent/ guardian. Children with major comorbidities, non-consenting parents/ guardians, and children transfused in the last 24-48 hours were excluded from the study. 05 ml of blood was collected from each child. G6PD qualitative tests were performed in the field; rest of the tests were carried out later at Dabgari Garden “”in lab. PCR was processed according to protocol. Data were analyzed by SPSS 26.0.Results:  A total sample size of 177 respondents were initially investigated through a qualitative test for G6PD deficiency. Among these, only 4 (2.3%) respondents were found to be G6PD deficient, The PCR analysis depicted that among 177 respondents, 31 (17.5%) were found to be mutant. Among these, 26(84%) were heterozygous, while 5 (16%) respondents were found to be homozygous. The PCR analysis further revealed that among the 5 homozygous respondents, 3 were found to be G6PD deficient, as also depicted by the qualitative test. One of the homozygous respondents, although found deficient by qualitative test, showed no Mediterranean mutation.Conclusion: Most studies done in Pakistan are hospital-based and the method for diagnosing is a qualitative test, but if the G6PD enzyme activity level is more than 30% qualitative test cannot pick the respondent as deficient. In our study, we ran qualitative tests on all respondents and only 4/177(2.3%), followed by PCR analysis for Mediterranean mutation of all samples, which showed that 31/177 (17.5%) were G6PD deficient. Further studies need to be conducted in the same manner to know the exact prevalence of G6PD. Detailed studies in other ethnic groups of the country must also be conducted to highlight the actual position of this threat.","PeriodicalId":15254,"journal":{"name":"Journal of Biology and Life Science","volume":"25 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-07-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85604188","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Diagnostic Performance of Direct Microscopic Techniques and Culture Media for Fungal Isolates from Hair Specimens","authors":"Faiza Zeeshan, F. Uddin, Suresh Kumar, Shahida Kashif, N. Jaffar","doi":"10.37185/lns.1.1.316","DOIUrl":"https://doi.org/10.37185/lns.1.1.316","url":null,"abstract":"Objective: To compare the diagnostic performance of direct microscopic techniques and culture media for detecting fungal isolates in hair specimens.Study Design:  Cross-sectional study.Place and Duration of Study: The study was conducted at the Department of Microbiology, Basic Medical Sciences Institute, Karachi, Pakistan, from January 2021 to June 2021.Materials and Methods:  A total of 207 hair specimens were collected from the patients with superficial mycoses of the scalp. The specimens were collected under aseptic techniques using clean glass slides and forceps which were processed for Potassium hydroxide mount and Calcofluor white staining. The mycological cultures were performed on a Dermatophyte test medium and Sabouraud Dextrose agar with and without antibiotics. The data was recorded and analyzed on SPSS version 21. The frequencies, percentages, means, and ratios were calculated using Descriptive statistics. The association between variables were analyzed by the Chi-square test and kappa index.Results: Potassium hydroxide mount revealed fungal spores and hyphae in 154(74.3%) specimens, while Calcofluor white staining showed fungal elements in 179(86.5%) specimens. Out of 207 specimens, 106(51.2%) were culture positive and 101(48.8%) were declared culture negative. Out of culture-positive specimens, dermatophytes were yielded in 61(57.5%) and non-dermatophytes in 45(42.5%) specimens. Among all culture media, the highest number of dermatophytes was yielded by plain Sabouraud dextrose agar (59; 96.5%), followed by dermatophyte test medium (55; 90%), and Sabouraud dextrose agar with antibiotics (54; 90.1%). On the contrary, the primary isolation of non-dermatophytes on the plain was Sabouraud dextrose agar s 32(71.1%), Sabouraud dextrose agar with antibiotics 31(68.2%), and dermatophyte test medium 13(28.8%).Conclusion: In our study, we found Calcofluor white staining technique as the most sensitive method to detect fungal elements from the given hair specimens. For mycological culture, all tested culture media were equally effective for the retrieval of dermatophytes. However, for non-dermatophytes, plain SDA and SDA with antibiotics were found to be better media for isolation.","PeriodicalId":15254,"journal":{"name":"Journal of Biology and Life Science","volume":"13 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-07-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82131138","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparison Between the Combination Therapy in Terms of Therapeutic Effectiveness and Anti-Microbial Efficacy in Extensive Drug-Resistant Acinetobacter Baumannii Infections","authors":"N. Parveen, Rana Imran Sikander, Muhammad Zeeshan, S. M. Muneeb Ali, Muhammad Hassan","doi":"10.37185/lns.1.1.312","DOIUrl":"https://doi.org/10.37185/lns.1.1.312","url":null,"abstract":"Objective: To compare the clinical and antimicrobial efficacy of a triple-antibiotic regimen (Colistin, Cefoperazone/Sulbactam, and Tigecycline) with a double-antibiotic regimen (Colistin and Minocycline) for treating drug-resistant Acinetobacter baumannii infections in critically ill patients.Study Design:  A comparative cross-sectional study design.Place and Duration of Study: The study was conducted at the Medical Intensive Care Unit (ICU) of Pakistan Institute of Medical Sciences (PIMS), Islamabad, Pakistan from April 2022 to October 2022.Materials and Methods: A total of 38 patients aged 18-70 years admitted to the Medical Intensive Care Unit (ICU) of the Pakistan Institute of Medical Sciences, Islamabad gave consent to participate in the study. Any patient having a culture-proven polymicrobial infection was excluded. A total of 20 patients were allocated to Group A (triple-antibiotic regimen) and 18 patients to Group B (double-antibiotic regimen). Vital statistics were recorded daily, while laboratory-based biochemical markers (leucocyte count, CRP, lactate, procalcitonin) were recorded every 48 hours for ten days. Antimicrobial efficacy was assessed by a culture analysis on the 10th day.Results: There were 20 patients in Group A and 18 in Group B. There were 32 patients with Ventilator-Associated Pneumonia (VAP), and six with bloodstream infection. No significant difference in the vitals and lab markers were found between the two groups. The only exception was serum lactate levels, which were significantly higher Group A (34.03 + 28.37 mg/dL), compared to Group B (16.11 + 15.63 mg/dL; p = 0.024). Group A therapy was also found to have significantly improved antimicrobial efficacy in terms of positive-culture results (n=4, 20%) compared to Group B (n=10, 55.6%; p = 0.023).Conclusion: The triple-antibiotic regimen had better antimicrobial efficacy than the double-antibiotic regimen for treating Acinetobacter baumannii-related infections.","PeriodicalId":15254,"journal":{"name":"Journal of Biology and Life Science","volume":"106 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-07-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88003404","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Emotional Intelligence and Conflict Resolution as a Predictor of Resilience in Rescue Workers","authors":"A. Malik, H. Rana, Rabbia Ashraf","doi":"10.37185/lns.1.1.331","DOIUrl":"https://doi.org/10.37185/lns.1.1.331","url":null,"abstract":"Objective: This research aimed to examine the relationship among emotional intelligence, conflict resolution, and resilience in rescue workers.Study Design: Cross-sectional study.Place and Duration of Study: The study was conducted in the Lahore head office of rescue1122. Data was collected for the period of 5 months from 2nd August to 2nd December 2022.Materials and Methods: The study comprised 210 rescue workers, age range between 22 to 40 years (M=30.74, SD=5.00), and data was collected from Lahore (n=89) and Bhakkar (n=121) cities of Punjab Province, Pakistan, by employing purposive sampling.Results: The results of the current study showed that there was a significant positive correlation between Emotional Intelligence, Conflict Resolution, and Resilience, whereas the subscales of Emotional Intelligence (Perception of Emotions and Managing Own Emotions) were strong predictors of Resilience. Significant differences in Emotional Intelligence and Conflict Resolution were found in rescue workers of Lahore and Bhakkar city, but the same level of Resilience was found in employees of both cities.Conclusion: The present research concluded that there is a positive and strong relationship between emotional intelligence, conflict resolution, and resilience which describes that higher emotional intelligence and conflict resolution become the reason to have an increase in resilience.","PeriodicalId":15254,"journal":{"name":"Journal of Biology and Life Science","volume":"43 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-07-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89155573","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Diagnostic Predicament of Persistent Electrolyte Imbalance in a Neonate, Pseudohypoaldosteronism (PHA)","authors":"Ahsan Ahmad Ghauri, Muhammad Usman Munir, Z. Haroon, Muhammad Younas","doi":"10.37185/lns.1.1.323","DOIUrl":"https://doi.org/10.37185/lns.1.1.323","url":null,"abstract":"Pseudohypoaldosteronism (PHA) type 1 is a heterogeneous group of disorder of electrolyte metabolism characterized by apparent renal tubular unresponsiveness to aldosterone action. PHA-1 is manifested by hyponatremia, hyperkalemia, metabolic acidosis and may present as salt wasting crisis with elevated levels of renin and aldosterone. PHA-1 is subdivided into two types with varying degree of severity. The earliest sign of both type of PHA-1 is poor weight gain due to dehydration and failure to thrive during infancy. Here, we report a case of renal PHA-1 in a 30 days old female infant who presented with hyponatremia, mild dehydration and hyperkalemia and was treated with dietary sodium chloride supplementation, potassium binding resin and fluid replacement therapy which proved to be lifesaving.","PeriodicalId":15254,"journal":{"name":"Journal of Biology and Life Science","volume":"18 3 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-07-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83188327","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}