Journal of Biology and Life Science最新文献

{"title":"Histopathological Study and Clinical Correlation of Glial Tumors at a Tertiary Care Hospital of Karachi","authors":"Javeria Khan, Irtiza Ahmed Bhatti, Nazish Jaffar, Ghulam Haider, Aliya Zaman, Shamama Muhamad Shabbir","doi":"10.37185/lns.1.1.337","DOIUrl":"https://doi.org/10.37185/lns.1.1.337","url":null,"abstract":"Objective: To observe the spectrum of glial tumors in a resource-limited tertiary care setup of Karachi according to the modified WHO central nervous system tumor classification.Study Design:A retrospective analysis.Place and Duration of Study: The study was conducted at the Oncology Ward of Jinnah Postgraduate Medical Centre (JPMC), Karachi, Pakistan from August 2020 to January 2021.Methods: The study was done to record data of patients diagnosed with glioma, which were registered during 2017 - 2019. Patients were classified according to recent WHO brain tumor classification. Data analysis as performed by SPSS version 26.0.Results: A total of 115 glioma cases were included. The most common presenting age group was in the 4th decade of their life. Oligodendroglioma was the most common histological type 61 (53.5%). The most common presenting symptom was a headache in 46 (40%). The location of the tumor was temporoparietal lobe in 51/115 (44.3%). Immunohistochemical studies showed a significant association with histological subtypes (p-value: 0.002). Conclusion: Oligodendroglioma was found to be the most common histological type. Immunohistochemical marker GFAP expression was positive for the majority of diagnosed cases, where 1p19q / codeletion was observed specifically in oligodendrogliomas.
 How to cite this: Khan J, Bhatt IA, Jaffar N, Haider G, Zaman A, Shabbir SM Histopathological Study and Clinical Correlation of Glial Tumors: Tertiary Care Setting in Karachi. Life and Science. 2023; 4(4): 481-486. doi: http://doi.org/10.37185/LnS.1.1.337","PeriodicalId":15254,"journal":{"name":"Journal of Biology and Life Science","volume":"302 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135547394","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Quality of Life of Medical and Nursing Students of a Private Institute of Wah Cantt","authors":"Shezadi Sabah Imran, Khola Waheed Khan, Sadia Nadeem, Robina Mushtaq, Musarat Ramzan","doi":"10.37185/lns.1.1.311","DOIUrl":"https://doi.org/10.37185/lns.1.1.311","url":null,"abstract":"Objective: Quality of life is an encompassing term dealing with multiple aspects of life, including physical, social, environmental & psychological domains. It is a measurement of the gap between what people wish to have & what they possess. The objectives were to assess the quality of life among medical & nursing students and evaluate the association of various demographic factors with the quality of life. Study Design: Cross-sectional study. Place and Duration of Study: The study was carried out at the Department of Community Medicine, Wah Medical College and Institute of Nursing, Wah Cantt, from January 2022 to June 2022. Methods: The study was conducted on 282 students; 188 medical and 94 nursing students, selected by applying systematic random and convenient sampling techniques respectively. A pre-tested questionnaire, including demographic information and questions related to the quality of life-based on the English version of WHOQOL-BREF, was used for data collection. The data was analyzed using SPSS version 23; frequencies and percentages of categorical variables were calculated. The mean scores of items within each domain were used to calculate the domain's score. To measure better scores in different domains, the percent score of each domain was calculated. The higher scores indicate a higher quality of life. An independent sample t-test was used to assess the association of factors like gender, age group, and place of living with the quality of life. The Pvalue of less than 0.05 was considered significant. Results: The score of the environmental domain was reported highest, followed by the physical, psychological, and social domains. The students living with their families had a better quality of life than the hostelites, P value of 0.009. Conclusion: It is ascertained that the quality of life of medical and nursing students is above average. Gender difference has no effect, but living with families favors a better quality of life among students.
 How to cite this: Imran SS, Khan KW, Nadeem S, Mushtaq R, Ramzan M. Quality of Life of Medical and Nursing Students of a Private Institute of Wah Cantt. Life and Science. 2023; 4(4): 487-491. doi: http://doi.org/10.37185/LnS.1.1.311","PeriodicalId":15254,"journal":{"name":"Journal of Biology and Life Science","volume":"61 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135547508","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect of Truncal Versus Branch Ligation of Inferior Thyroid Artery on Postoperative Hypocalcemia Patients Undergoing Thyroid Surgery: Rawalpindi","authors":"Romassa Javed, Muhammad Qasim Butt, Mansoor Tariq, Rohan Qamar, Sarah Tauseef Bukhari","doi":"10.37185/lns.1.1.366","DOIUrl":"https://doi.org/10.37185/lns.1.1.366","url":null,"abstract":"Objective: To investigate the effect of truncal or branch ligation of the inferior thyroid artery on postoperative hypocalcemia. Study Design: Quasi-experimental study.Place and Duration of Study: The study was conducted at the Department of Surgery, Pak Emirates Military Hospital (PEMH), Rawalpindi, Pakistan from July 2021 to June 2022.Methods: For this study, 60 patients were enrolled who underwent total thyroidectomy at the Department of Surgery from July 2021 to June 2022. Patients were divided into Group 'A' and Group 'B', with an equal number of 30 patients in each group. Patients in group 'A' underwent bilateral ITA ligation at the trunk, while patients in group 'B' underwent ligation of terminal branches of ITA on the gland capsule. The primary outcome was postoperative hypocalcemia on 1 postoperative day.Results: Our results showed a significant difference in hypocalcemia in both groups. Decreased incidence of biochemical hypocalcemia was found in branch ligation of ITA (3.33%) than trunk ligation (36.36%) P value 0.025.Conclusion: Branch ligation of ITA decreases the incidence of hypocalcemia after total thyroidectomy.
 How to cite this: Javed R, Butt MQ, Tariq M, Qamar R, Bukhari ST. Effect of Truncal Versus Branch Ligation of Inferior Thyroid Artery on Postoperative Hypocalcemia Patients Undergoing Thyroid Surgery: Rawalpindi. Life and Science. 2023; 4(4): 452-457. doi: http://doi.org/10.37185/LnS.1.1.366","PeriodicalId":15254,"journal":{"name":"Journal of Biology and Life Science","volume":"126 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135547684","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Reliability and Validity of the COPE Index among Caregivers of Hemodialysis Patients in Pakistan","authors":"Sumaira Nasim, Nicola M. Lowe, Victoria Hall Moran, Stephanie Dillon, Sidra Zaheer, Ian Philp","doi":"10.37185/lns.1.1.351","DOIUrl":"https://doi.org/10.37185/lns.1.1.351","url":null,"abstract":"Objective: To assess the reliability and validity of the COPE (Carers of Older People in Europe) index tool among the caregivers of dialysis-dependent patients in Pakistan.Study Design: Cross-sectional study.Place and Duration of Study: The study was conducted at the Dialysis Unit of Pakistan Kidney Patients Association Rawalpindi, Bahria International Hospital Rawalpindi and Fauji Foundation Hospital Rawalpindi, Pakistan, from December 2018 to January 2019. Methods: A 15-item COPE index questionnaire was administered, and data were collected from 124 caregivers of patients undergoing regular hemodialysis. A Principal Component Analysis (PCA) was performed on all items of the COPE index to retain the underlying components. Further, Cronbach's alpha was used to assess the internal consistency of the retained component structure and loadings obtained from the PCA and the entire instrument separately.Results: The PCA analysis revealed that, with the context of this study, the COPE index had good internal consistency for the negative aspects of caregiving and social support (Cronbach's alpha scores were 0.864 and 0.781, respectively). For the positive impact items, a Cronbach's alpha score of 0.655 indicated modest internal consistency. Cronbach's alpha of 0.714 for the entire 15 items indicated that the COPE index had good overall internal consistency in our study population.Conclusion: The COPE index was found to be a valid tool for use in Pakistan to assess the caregiver experience, including both positive and negative aspects of caregiving.
 How to cite this: Nasim S, Lowe NM, Moran VH, Dillon S, Zaheer S, Philp I. Reliability and Validity of the COPE Index among Caregivers of Hemodialysis Patients in Pakistan. Life and Science. 2023; 4(4): 393-400. doi: http://doi.org/10.37185/LnS.1.1.351
","PeriodicalId":15254,"journal":{"name":"Journal of Biology and Life Science","volume":"32 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135547393","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Risk Factors of Obesity in the Adult Population of Pakistan","authors":"Rumza Mehr un Nisa Nomani, Aleena Khan, Syed Tahir Abbas Shah, Aisha Naeem, Afrose Liaquat, Muhammad Jawad Khan","doi":"10.37185/lns.1.1.433","DOIUrl":"https://doi.org/10.37185/lns.1.1.433","url":null,"abstract":"Objective: This study was conducted to find the prevalence of obesity in Pakistan and establish the link to know associated risk factors of obesity within the obese population. Study Design: Cross-sectional study.Place and Duration of Study: The study was carried out in the Functional Genomics Laboratory at the Department of Biosciences, COMSATS University, Islamabad, Pakistan from November 2017 to December 2021.Methods: A survey of 1061 individuals (55.97% males and 44.03% females) was conducted which was a national representation of the Pakistani population. The data variables were presented as numbers and analyzed by Chi-square.Results: Among our study population, 16.71% were obese, 22.9% overweight, and 36.28% had normal body mass index (BMI). Out of 177 obese participants, 63.27% were in Class 1, 25.43% were in Class 2, and 11.3 % were classified as Class 3 obesity. Among obese, males and females were 57.63% and 42.37% respectively. Individuals aged 26-39 were found to be more obese than other age groups. A total of 31.64% of obese individuals were in the age group 18-25, 42.36% were in adulthood (26-39), 15.26% were in middle age (40-54) and 10.74% were in old age (55 and above). Most of the respondents were not suffering from any metabolic disease (81.53%), and 18.47% presented one or more than one metabolic disease. Metabolic complications, smoking, and history of obesity, dietary intake, and physical activity were found significantly associated with health status.Conclusion: Increase in obesity among Pakistani adults was presented equally in both genders and in all regions. It is significantly associated with several risk factors including history of obesity, physical activity, and dietary intake
 How to cite this: Nomani RMN, Khan A, Shah STA, Naeem A, Liaquat A, Khan MJ. Risk Factors of Obesity in the Adult Population of Pakistan. 2023; 4(4): 379-386. doi: http://doi.org/10.37185/LnS.1.1.433","PeriodicalId":15254,"journal":{"name":"Journal of Biology and Life Science","volume":"474 2 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135547507","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Past, Present and Future of Biomaterials","authors":"Wasim Alamgir, Adnan Haider","doi":"10.37185/lns.1.1.500","DOIUrl":"https://doi.org/10.37185/lns.1.1.500","url":null,"abstract":"Biomaterials are substances that can be introduced into the body or tissue for a wide array of therapeutic or diagnostic purposes. Biomaterials can be of both natural or synthetic origin. The first examples describing the use of biomaterials includes the Neanderthals use of wood as dental implanting materials, and from 7th BC to the 4th AD, the ancient civilizations of Greece and Rome used various other naturally occurring substances and metals for treatment of wounds and other medical complications. In 16th century in Europe, silver and gold materials were used for dental repair and iron threads were used for bone repairs and various immobilization procedures.1 Significant advancement has been made in the field of biomaterials in the recent decades, and both natural and synthetic biomaterials have been effectively used to replace various human tissues such as teeth, ligaments, tendons, bones, and load-bearing implants. The biocompatibility, bioactivity, and mechanical properties of biomaterials plays a pivotal role in meeting the need for long-term implants and bone replacement. Biomaterials in use include but are not limited to metal-based biomaterials (titanium alloys, alumina, stainless steel, zirconia, cobalt-chromium alloys) and polymer-based biomaterials (polymethyl methacrylate and ultra-high molecular weight polyethylene). These are usually selected because they meet the required criteria of mechanical strength, biocompatibility, and desired physical and chemical properties. Considerable progress has been made in improving the effectiveness of artificial joints, reducing wear, and extending the life of implants or prostheses inserted into the human body.2,3 Until recently, the focus had been on biomaterials as replacement materials. However, the main issue is immune rejection of the introduced material. Therefore, the focus has changed to using biomaterials for tissue regeneration. A viable cellular construct in a controlled laboratory environment for the purpose of transplantation can be achieved by using bioactive scaffolds that provide a structured environment to support cell growth and their function. Another strategy has been to trigger tissue regeneration within the body itself by using porous meshes or degradable bioactive materials which can facilitate the process.2 These techniques pose a risk of infection. Extensive research is currently underway to address these problems. In a recent study, scientists have successfully fabricated a composite scaffold of cellulose and silver nanoparticles.4 This innovative scaffold showed promising properties in preventing microbial infections and has the potential to prevent infections at wound sites.However, while it is important to acknowledge the above-mentioned beneficial properties of biomaterials; there is still a long way to go to achieve the desired goals. Immunomodulating biomaterials have been developed with the potential to effectively overcome common chronic diseases such as type 1","PeriodicalId":15254,"journal":{"name":"Journal of Biology and Life Science","volume":"124 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135547502","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Do Alpha-Ketoanalogues Slow Down Disease Progression in Non-Dialysis Dependent Chronic Kidney Disease?","authors":"Bilal Saeed, Khayam ., Zabihullah Afridi, Muhammad Sana Ullah","doi":"10.37185/lns.1.1.407","DOIUrl":"https://doi.org/10.37185/lns.1.1.407","url":null,"abstract":"Objective: To observe the effectiveness of keto-analogues in slowing down the disease progression in non-dialysis dependent CKD patients.Study Design: Quasi-experimental study.Place and Duration of Study: The study was carried out at Nephrology Department of Combined Military Hospital (CMH), Peshawar, Pakistan from August 2022 to 28 February 2023.Methods: Data was collected on 290 kidney disease improving global outcomes (KDIGO) stage 3 and 4 CKD patients through non-probability consecutive sampling technique. The cohort was divided into group A (Low protein diet) and B (ketodiet). Group A received low protein diet in addition to standard chronic disease treatment while Group B was labelled as keto-diet group which received ketoanalogues in addition to low protein diet and standard chronic kidney disease treatment. Baseline and six months eGFR was calculated and compared for both groups. SPSS version 23.00 was used for data analysis. The P value ≤ 0.05 was considered significant.Results: 286 patients aged 51.84±18.127 were selected for our study. 188(65.73%) were males while females were 98 (34.26%). There were 142 (50.34%) and 144(50.34%) patients in group A and B respectively. Duration of CKD in group A and B was 6.45±2.55 and 6.49±1.75 years respectively. The means difference of eGFR in group A (low protein diet) at baseline and after six months was 3.64±1.09mL/ min/ 1.73m2 while that of group B was 1.48±0.41 mL/ min/ 1.73m2 (P-value<0.000). Conclusion: Ketoanalogues is an emerging therapy which slows down disease progression in non-dialysis dependent CKD patients. Although its use is recommended by some clinicians in CKD stage 3 and 4 non-dialysis dependent but still controversial.&#x0D; How to cite this: Saeed B, Khayam, Afridi Z, Ullah MS. Do Alpha-Ketoanalogues Slow Down Disease Progression in Non-Dialysis Dependent Chronic Kidney Disease?. Life and Science. 2023; 4(4): 427-431. doi: http://doi.org/10.37185/LnS.1.1.407","PeriodicalId":15254,"journal":{"name":"Journal of Biology and Life Science","volume":"302 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135547499","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Intracranial Spread of Infections Among the Patients of Chronic Suppurative Otitis Media","authors":"Muhammad Imran Malik, Aiman Fatima Naqvi, Syeda Uzma Naqvi, Nida Khan, Aijaz Ali, Najaf Abbas","doi":"10.37185/lns.1.1.476","DOIUrl":"https://doi.org/10.37185/lns.1.1.476","url":null,"abstract":"Objective: To determine the frequency of intracranial spread of infections among the patients of chronic suppurative otitis media presenting at a tertiary care hospital in Karachi.Study Design: Cross-Sectional Study.Place and Duration of Study: The study was carried out at the Department of ENT, Head and Neck Surgery, Dow Medical College, Dr. K.M Ruth Pfau Civil Hospital, Karachi, Pakistan, from January 2021 to January 2022.Methods: Out of 87 patients with Chronic Suppurative Otitis Media were included using a non-probability sampling technique. Possible routes of spread of infections were identified based on per operative findings. The Descriptive statistics were applied to all parameters. On inferential statistics, Chi-square test was used for stratification, considering p-value ≤0.05 as significant.Results: 75 (86.2%) were male and 12 (13.8%) were female. 21 (24.1%) patients were found with meningitis, 11 (12.6%) with lateral sinus thrombosis, and 2 (2.3%) with otitis hydrocephalus. As far as signs and symptoms are concerned, 87 (100%) patients had a headache, 74 (85.1%) had nausea and vomiting, 44 (50.6%) patients had vertigo, 43 (49.4%) had a fever, 18 (20.7%) had diplopia, and 73 (83.9%) had altered consciousness. 69 (79.3%) of patients' route of infection in the patients of chronic suppurative otitis media had bone erosion, 12 (13.8%) had thrombophlebitis, and 6 (6.9%) had anatomical pathways. Among different sites of spread of infection, the most common site was sinodural angle 45 (51.72%).Conclusion: Bone erosion, with 79.3%, was the most prevalent route of intracranial spread, followed by thrombophlebitis and anatomical pathways.&#x0D; How to cite this: Malik MI, Naqvi AF, Naqvi SU, Khan N, Ali A, Abbas N. Routes and Sites of Intracranial Spread of Infections Among the Patients of Chronic Suppurative Otitis Media. Life and Science.2023; 4(4): 476-482. doi: http://doi.org/10.37185/LnS.1.1.476","PeriodicalId":15254,"journal":{"name":"Journal of Biology and Life Science","volume":"179 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135547500","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Discrimination of Brain Abscess and Necrotic Brain Tumor with Proton MR Spectroscopy and Diffusion-Weighted Imaging","authors":"Hammad Saqib, Aisha Asghar, Atqa Firdous, Mahwish Zahra, Zia Ul Islam, Samreen Mushtaq","doi":"10.37185/lns.1.1.431","DOIUrl":"https://doi.org/10.37185/lns.1.1.431","url":null,"abstract":"Objective: To compare the efficacy of MR spectroscopy and diffusion-weighted imaging in discriminating between cystic or necrotic tumors and pyogenic brain abscesses.Study Design: A retrospective study design.Place and Duration of Study: The Study was conducted at the Radiology Department of Nishtar Hospital Multan and General Hospital Lahore, Pakistan, from January 2022 to January 2023. Methods: A total ten patients were included in the study. Of 10 patients, 5 had pyogenic abscesses, and 5 had tumors. Tumors were metastases (2 patients), glioblastomas (2 patients), and anaplastic astrocytoma (1 patient). Proton MR spectroscopy and diffusion-weighted imaging were performed in all patients. Results: Results showed that significant resonance lines (creatine/phosphocreatine, N-acetyl aspartate, and choline) observed in normal brain parenchyma were missing in abscesses or necrosis. MR spectroscopy of abscess showed multiple resonance peaks. Diffusion-weighted images showed that all pyogenic abscesses had lower ADC values and were hyperintense compared to normal brains. Conclusion: Diffusion-weighted imaging is more accurate and less time consuming method for discrimination of brain lesions compared to MR spectroscopy.&#x0D; How to cite this: Saqib HA, Asghar A, Firdous A, Zahra M, Islam Z, Mushtaq S. Discrimination of Brain Abscess and Necrotic Brain Tumor with Proton MR Spectroscopy and Diffusion Weighted Imaging. Life and Science. 2023; 4(4): 432-437. doi: http://doi.org/10.37185/LnS.1.1.431","PeriodicalId":15254,"journal":{"name":"Journal of Biology and Life Science","volume":"61 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135547501","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Decision to Delivery Interval of Emergency Caesarean Sections: Evaluating Adherence to Timeframe and its Impact on Feto-Maternal Outcomes","authors":"Shagufta Parveen, Saad Waqar","doi":"10.37185/lns.1.1.424","DOIUrl":"https://doi.org/10.37185/lns.1.1.424","url":null,"abstract":"Objective: To evaluate the decision to delivery interval (DDI) of category-1 and category-2 emergency caesarean section (ECS) and its effect on neonatal and maternal outcomes.Study Design: Cross-sectional study.Place and Duration of Study: The study was carried out at Combine Military Hospital (CMH), Kharian, Pakistan from February 2022 to February 2023.Methods: Data from 332 patients who underwent emergency caesarean section (ECS) at a tertiary care hospital were collected on a structured proforma and analyzed. Feto-maternal outcomes were dependent, and time to decision to delivery interval were independent variables.Results: Out of 332 ECS, 126 were Category 1, and 206 were category 2. The percentages of emergency caesarean section (ECS) done within the recommended DDI were 39.5% for category 1 and 20.5% for category 2. The median (IQR) of DDI was 45 (37–54) min and 90 (75–98) min for category 1 and category 2. Eclampsia, fetal distress and failed progress of labor were the most typical indications. In both types, there was no statistically significant poor neonatal outcome related to APGAR at 1 min and 5 min. Delays were associated with more cases of post-operative fever 74 (36) and 22(13.3) in category 2 than in category 1 ECS.Conclusion: Our study found delays in the decision-to-delivery interval (DDI) for both category 1 and category 2 emergency Caesarean sections. However, no statistically significant association was found between neonatal and maternal outcomes.&#x0D; How to cite this: Parveen S, Waqar S. Decision to Delivery Interval of Emergency Caesarean Sections: Evaluating Adherence to Timeframe and its Impact on Feto-Maternal Outcomes. Life and Science. 2023; 4(4): 445-451. doi: http://doi.org/10.37185/LnS.1.1.424","PeriodicalId":15254,"journal":{"name":"Journal of Biology and Life Science","volume":"128 7 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135547505","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}