Journal of Cardiovascular Disease Research最新文献

{"title":"Study of Extrathoracic Subclavian/Axillary Vein Puncture with a Novel Technique using Micro-Wire as a Guide for Device Lead Implantation","authors":"A. Lone, I. Hafeez, I. Bhat, A. Rashid, J. Beig, N. Tramboo","doi":"10.5530/jcdr.2018.4.41","DOIUrl":"https://doi.org/10.5530/jcdr.2018.4.41","url":null,"abstract":"Background: Cannulation of veins for Cardiovascular implantable electronic devices (CIED) therapy always involves some risk of complication. To prevent lead related complications, most operators now prefer large veins like proximal part of subclavian vein and axillary vein. A novel technique of subclavian/axillary vein puncture is described where a “microwire”, a routine 0.014 PCI wire is used as a guide to obtain vascular access. Aims and Objectives: To study safety and efficacy of a novel technique of subclavian/axillary vein puncture using a microwire. Materials and Methods: 67 adult patients admitted for routine device therapy requiring 114 lead implantations were included. A 20 gauge IV cannula was introduced on medial side of anticubital area in ipsilateral arm. Through this cannula, PCI wire was advanced via axillary vein to right atrium under fluoroscopy. Same microwire was used to guide access of subclavian/ axillary vein over first rib. Results: One patient was excluded due to absence of any visible vein. In 66 patients, all 112 subclavian/axillary vein cannulations were successfully performed using microwire guidance technique. Success was achieved in first attempt for 86 (76.8%), in second attempt for 18 (16%) and in third attempt for 8 (7.2 %) punctures. No complications related to punctures were observed. Conclusion: This technique of extra-thoracic, subclavian/axillary vein cannulations using a ‘micro-wire’ introduced through ipsilateral arm vein is simple, safe and more predictable for device lead implantation. Puncture is virtually done under vision as radiopaque micro-wire serves as a real-time landmark of position and course of vein over first rib.","PeriodicalId":15222,"journal":{"name":"Journal of Cardiovascular Disease Research","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41946493","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Association of Serum Soluble Receptor for Advanced Glycation End Products (sRAGE), S100A12 and Pulse Pressure Value in Coronary Artery Disease Patients","authors":"Deeraj Mungun, I. Zakaria, Xiang-ming Wang, Lu Miao, T. Tu, Yan Guo","doi":"10.5530/jcdr.2018.4.39","DOIUrl":"https://doi.org/10.5530/jcdr.2018.4.39","url":null,"abstract":"","PeriodicalId":15222,"journal":{"name":"Journal of Cardiovascular Disease Research","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42791803","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Effect of Electromagnetic Fields Emitted from Mobile Phone on qt Intervals and Dispersion Among Hypertensive Subjects","authors":"A. Oluwole, O. Familoni, T. Olunuga","doi":"10.5530/jcdr.2018.4.36","DOIUrl":"https://doi.org/10.5530/jcdr.2018.4.36","url":null,"abstract":"Background: There is increasing public concern about the possible health risks associated with the electromagnetic field emitted by mobile phones with conflicting data about these risks. Prolonged QT interval and or increased dispersion have been associated with increased cardiovascular risk and mortality in health and diseased states even among hypertensives. Aim: To study the effects of electromagnetic field emitted from mobile phone on QT intervals and dispersions among hypertensives. Subjects and Methods: 100 hypertensive patients were compared with age and sex matched controls. Five sets of 12 lead resting ECGs were obtained from each participant, baseline ECG obtained without mobile phone. ECGs were obtained during 4 experimental settings: Mobile phone over the precordium turned ON not ringing, then in RINGING mode; then at the hip level turned ON and lastly on hip RINGING.QT interval and dispersion were manually measured from each of the ECGs. Results: Overall, there tended to be the longest QT intervals with the phone ringing on the precordium of hypertensive patients, though this was not statistically significant with ANOVA. However there was significant prolongation of the QTc intervals in hypertensives with the phone ringing on precordium compared to hip QTc (432.84+24.38 vs 430.72 +26.40 ms, p= 0.038); QTcmax (455.04+27.78 vs 450.28+27.77msecs p=0.002). This trend was absent however with QT dispersions. All the baseline QT intervals were longer in hypertensives compared with controls. Conclusion: Short-term exposure to electromagnetic field emitted by mobile phone interferes with QT intervals in hypertensive patients particularly when ringing on the precordium.","PeriodicalId":15222,"journal":{"name":"Journal of Cardiovascular Disease Research","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44505063","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Blood Urea Nitrogen, Creatinine and Urea Nitrogen-to-creatinine Ratio as Predictors of In-Hospital Adverse Cardiac Events in Acute Myocardial Infarction","authors":"A. B. Hartopo, Ira Puspitawati, I. A. Arso, B. Setianto","doi":"10.5530/JCDR.2018.4.37","DOIUrl":"https://doi.org/10.5530/JCDR.2018.4.37","url":null,"abstract":"Background: Kidney dysfunction affects cardiovascular outcome in patients with acute myocardial infarction. Creatinine, urea nitrogen and urea nitrogen-to-creatinine ratio (UCR) are kidney biomarkers routinely measured in patients with acute myocardial infarction. Their implication in acute myocardial infarction has not been validated. Aims: The study aims to investigate the association between urea nitrogen, creatinine and UCR and in-hospital adverse cardiac events in patients with acute myocardial infarction. Methodology: The study design was cohort. Subjects were patients with acute myocardial infarction. Blood urea nitrogen and creatinine were measured on admission. The UCR was calculated as ratio of urea nitrogen to creatinine. The observation was performed during hospitalization in ICCU to detect the adverse cardiac events, i.e. death, acute heart failure, cardiogenic shock, reinfarction and rescucitated ventricular arrhytmia. The ROC curve was designed to determine the cut-off point of high urea nitrogen, creatinine and UCR. The bivariate and multivariable analysis were performed to establish the independent predictors of adverse cardiac events. A p value < 0.05 was a limit of statistics significance. Results: The subjects of this research were 424 patients. Among them, 96 subjects (22.6 %) developed in-hospital adverse cardiac events. Subjects with adverse cardiac events had significantly higher level of urea nitrogen, creatinine and UCR. The bivariate analysis showed that high urea nitrogen, high creatinine and high UCR were associated with adverse cardiac events. The multivariable analysis showed only high urea nitrogen as an independent predictor for adverse cardiac events (adjusted OR 3.14 (95 % CI:1.37-7.19, p value 0.007)). Conclusion: High urea nitrogen, creatinine and UCR were associated with increased in-hospital adverse cardiac events. Only high urea nitrogen was an independent predictor for in-hospital adverse cardiac events in patients with acute myocardial infarction.","PeriodicalId":15222,"journal":{"name":"Journal of Cardiovascular Disease Research","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44973671","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cholinesterase Levels in Cord Blood in Preeclamptics","authors":"Kharb Simmi, P. Prerna, K. Vikas, Ghalaut Veena Singh, J. Bala, N. Smiti","doi":"10.5530/jcdr.2018.4.35","DOIUrl":"https://doi.org/10.5530/jcdr.2018.4.35","url":null,"abstract":"Objective: Human placenta, a non-neural tissue, contains cholinergic system and high affinity muscarinic receptors. Role of Cholinesterases (CE) in trophoblast function and pregnancy is not clear. The present study was planned to analyse cholinesterase (CE) levels in cord blood in preeclamptic women. Materials and Methods: Cholinesterase levels were analyzed in maternal and cord blood in women with preeclampsia (n=25) and compared with those of normotensive pregnant women (n=25) and normal, healthy controls (n=25) by kinetic method (new DGKC method) using auto analyzer. Results: Cholinesterase levels were lower in maternal blood of preeclamptics as compared to normotensive controls. Cord blood cholinesterase levels were lowered in babies of normotensives and cord blood CE levels were 88.65% of the maternal levels. Cord cholinesterase levels were significantly lowered in preeclamptic as compared to normotensive pregnant. On comparing CE levels with normal control (Group III) it was observed that CE levels were significantly raised both in normotensive as well as preeclamptic women. Conclusion: Findings of the present study indicate that decrease in cholinesterase levels in preeclampsia via loss of muscarinic cholinergic receptors occurring in preeclampsia.","PeriodicalId":15222,"journal":{"name":"Journal of Cardiovascular Disease Research","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46408030","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Study and Construction of New Polymeric Electrodes in PVC Matrix Membrane for Amiloride Hydrochloride Drug Determination","authors":"S. A. Abrahem, S. Ibrahim, A. Kader","doi":"10.33422/2nd.icarbme.2019.12.945","DOIUrl":"https://doi.org/10.33422/2nd.icarbme.2019.12.945","url":null,"abstract":"Based on Amiloride hydrochloride-methyl orange, two electrodes of Amiloride hydrochloride were constructed in PVC matrix as ion pair complex. They were plasticized using Nitrobenzene (NB), and Di-butyl phosphate (DBP). Amiloride hydrochloride (AMH) electrodes (e1and e2) presented slopes (54.210 and 52.810 mV/decade) and linear ranges (10-5-10-2, and 2*10-5-10-2 M), respectively. (e1), which is the best electrode, was based on DBP plasticizer. It gave a detection limit of 4x10-6M, slope of 54.210 mV/decade, correlation coefficient 0.9998, lifetime 36 days. The proposed electrode displayed reproducibility and good stability and was used for determining Amiloride hydrochloride in pharmaceutical samples. The interference measurements using (Na+, Cu+2, K+, Fe+3, and Mn+2) were studied for selectivity coefficient determination using the separated method, as well as the mixed method","PeriodicalId":15222,"journal":{"name":"Journal of Cardiovascular Disease Research","volume":"11 1","pages":"150-155"},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69745264","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Selected Cardiometabolic Risk-Factor Clusters of Urban Hypertensive Adults in Response to 72-hour ABU f.m. Call for Free-Medical Screening","authors":"O. Onyemelukwe, B. Maiha, T. Dahiru, N. Madugu, M. Aliyu, L. Ayanwuyi, I. Mudashir, K. Rahman, C. Chukwumerije, U. Adamu, L. Okonkwo, O. Bolaji, I. Okpe, A. Bakari","doi":"10.5530/JCDR.2018.11.XX","DOIUrl":"https://doi.org/10.5530/JCDR.2018.11.XX","url":null,"abstract":"","PeriodicalId":15222,"journal":{"name":"Journal of Cardiovascular Disease Research","volume":"10 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71057273","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect of Simulated Geomagnetic Activity on Myocardial Ischemia / Reperfusion Injury in Rats","authors":"Huisheng Wu, Weiyu Chang, Yanglin Deng, Xinli Chen, Yongli Ding, Xuesong Li","doi":"10.5530/jcdr.2019.10.x","DOIUrl":"https://doi.org/10.5530/jcdr.2019.10.x","url":null,"abstract":"","PeriodicalId":15222,"journal":{"name":"Journal of Cardiovascular Disease Research","volume":"10 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71057911","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Negative Stress Echocardiography in the Setting of Acute Myocardial Infarction","authors":"Mahmoud Abdelghany, S. Pruthi, Luna Bhatta, R. Carhart","doi":"10.5530/JCDR.2019.11.X","DOIUrl":"https://doi.org/10.5530/JCDR.2019.11.X","url":null,"abstract":"","PeriodicalId":15222,"journal":{"name":"Journal of Cardiovascular Disease Research","volume":"10 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71058398","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effectiveness of Panchkarma Based Heart Failure Reversal Therapy in Patients of Heart Failure with Diabetes Mellitus: An Observational Study","authors":"M. SaneRohit, A. SuleVarada, Wahane Shweta, Kore Rupali, R. Vrushali, Wajge Archana, S. MandoleRahul","doi":"10.5530/jcdr.2019.x.x","DOIUrl":"https://doi.org/10.5530/jcdr.2019.x.x","url":null,"abstract":"","PeriodicalId":15222,"journal":{"name":"Journal of Cardiovascular Disease Research","volume":"10 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71058623","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}