Journal of Cardiovascular Disease Research最新文献

{"title":"Assessment of Coronary Bifurcation Stenting using Optical Coherence Tomography","authors":"G. Paramasivam, R. Vijayvergiya","doi":"10.5530/jcdr.2019.3.16","DOIUrl":"https://doi.org/10.5530/jcdr.2019.3.16","url":null,"abstract":"Coronary bifurcation lesions constitute about 15 20% of total percutaneous coronary interventions (PCI).1 Bifurcation PCI is technically challenging despite improvement in techniques and devices. Side-branch occlusion occurs in about 10% of bifurcation PCI cases.2 The long-term clinical outcome is also poor in these cases compared to non-bifurcation PCI.3,4 Conventional coronary angiography has several limitations in assessing this complex bifurcation site, both before and after PCI.1 Intravascular imaging has helped in better assessment of bifurcations lesions and improved procedural outcomes.5,6 Recently, with frequent use of high-resolution optical coherence tomography (OCT), these lesions can be better-assessed preand post-PCI.1,7 We evaluate the use of OCT for PCI optimization in bifurcation lesions, using provisional one-stent and elective two-stent strategies.","PeriodicalId":15222,"journal":{"name":"Journal of Cardiovascular Disease Research","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-10-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42216102","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Is Galectin 3 more Accurate than Brain Natriuretic Peptide in Diagnosing Chronic Heart Failure? A Systematic Review","authors":"Ampofo Ama Gyamfua, K. Ehsan, B. M. Ibitoye","doi":"10.5530/jcdr.2019.3.17","DOIUrl":"https://doi.org/10.5530/jcdr.2019.3.17","url":null,"abstract":"Heart failure (HF) is a clinical syndrome in which the pumping action of the heart is impaired. Globally, more than 23 million people are affected by HF1,2. Also, about 160,000 people across the United Kingdom and 5.8 million people suffer from HF in the United States of America and contribute to 50,000 deaths annually in the United States of America. The main cause of HF has been attributed to left ventricular failure3,4. It has been estimated that about 58% of the population affected by HF following myocardial infarction is often asymptomatic5. Therefore, often misdiagnosed or underdiagnosed in primary care6. Hence, asymptomatic AMI can lead to symptomatic HF that may masquerade as COPD. This is important as a good biomarker will help identify the problem more accurately before individual suffering from HF deteriorates.","PeriodicalId":15222,"journal":{"name":"Journal of Cardiovascular Disease Research","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-10-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46457796","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Optimal Coronary Evaluation and Management of Patient with Shepherd`s Crook Right Coronary Artery","authors":"Y. Song, Sang-Hoon Seol, Jino Park, Seunghwan Kim, Dong-Kie Kim, Ki-Hun Kim, D. Kim","doi":"10.5530/JCDR.2019.2.13","DOIUrl":"https://doi.org/10.5530/JCDR.2019.2.13","url":null,"abstract":"Shepherd’s crook deformity of right coronary artery is a unique condition of dramatic upturn with a near 180oC switchback turn. It is a challenge for interventionist to perform percutaneous coronary intervention in case of severe tortuous artery with atherosclerosis. Many tips, techniques and devices have been developed to overcome technical issues. We present an interesting case of 64-year-old male with extreme tortuosity of RCA who had difficulty in assessing the lesion characteristics.","PeriodicalId":15222,"journal":{"name":"Journal of Cardiovascular Disease Research","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-07-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47924740","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Metabolic Syndrome (MetS) Does not Confer Additional Risk Above and Beyond its Individual Components for Left Ventricular Remodeling","authors":"R. Prakaschandra, D. P. Naidoo","doi":"10.5530/JCDR.2019.2.11","DOIUrl":"https://doi.org/10.5530/JCDR.2019.2.11","url":null,"abstract":"Introduction: The detection of preclinical changes in Left Ventricular (LV) structure in the Metabolic Syndrome (MetS) has not been adequately studied, although MetS is strongly associated with increased cardiovascular risk. The influence of the MetS and its individual components on LV geometry across age groups in a cohort of SA Indians was studied. Method: Data on 902 randomly selected participants, a sub-group of the Phoenix Lifestyle project was studied. Detailed methodology has been previously published. The MetS was defined according to the harmonised criteria, hypertension according to the JNC criteria, diabetes according to the American Diabetes Association criteria and echocardiography according to the European Society of Echocardiography guidelines. Results: Normal LV geometry was found in 80.8%, eccentric hypertrophy 15.9%, concentric hypertrophy 3.2%, concentric remodelling 0.5%. Logistic regression with MetS as the only independent variable strongly predicted the presence of both concentric (OR = 4.36 CI 1.84, 10.3 p<0.0001) and eccentric hypertrophy (OR = 3.15 CI 2.15, 4.62; p=0.001). When all MetS component risk factors were adjusted for each other, independent predictors for the eccentric hypertrophy were the waist circumference (p=0.002; OR= 2.95 CI 1.49, 5.84), fasting glucose (p= 0.021; OR= 1.7 CI 1.1, 2.7) and Blood Pressure (BP) (p=0.005; OR= 1.78 CI 1.19; 2.71). Conclusion: The MetS is not associated with any additional risk for LV remodelling beyond its individual risk factor components. The main determinants of LV remodelling appear to be mediated by the effects of the increased waist circumference, increased blood glucose and BP.","PeriodicalId":15222,"journal":{"name":"Journal of Cardiovascular Disease Research","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-07-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71058414","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Association of Vitamin D Level with Severity of Angiographically Documented Coronary Artery Disease: Observations from Bangladeshi Patients","authors":"Ashraf Ur Rahman, P. Karmakar, S. Jabeen, S. Nabi, A. Khan, S. Shahriar, Iftequar Alam, Shubhra Chakraborty, M. Matin, S. A. Azam","doi":"10.5530/JCDR.2019.2.10","DOIUrl":"https://doi.org/10.5530/JCDR.2019.2.10","url":null,"abstract":"","PeriodicalId":15222,"journal":{"name":"Journal of Cardiovascular Disease Research","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-07-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43243471","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Rare Presentation of Wegners Granulomatosis as Complete Heart Block","authors":"Rahul Singla, N. Waghmare, Aniruddha M. Kaushik, Anil Kumar, N. Bansal","doi":"10.5530/JCDR.2019.2.14","DOIUrl":"https://doi.org/10.5530/JCDR.2019.2.14","url":null,"abstract":"Cardiac involvement is seen in 6 to 25% Wegener’s granulomatosis, but very rarely it can involve the conduction system and manifest as complete heart block. Earlier most of the case reports were with systemic variant rather than a limited variant. We report a case of complete Heart Block (3rd degree) in a case of limited Wegner granulomatosis which was treated with Permanent Pacemaker Implantation. Complete AV block is a rare but treatable manifestation of cardiac involvement of wegners granulomatosis usually associated with early active systemic disease. All patients diagnosed with Wegener’s granulomatosis should be screened with a baseline electrocardiogram and a transthoracic echocardiogram to document cardiac involvement and alert clinicians to those at risk of further cardiac complications.","PeriodicalId":15222,"journal":{"name":"Journal of Cardiovascular Disease Research","volume":"104 6","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-07-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41245030","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Correlation Between BMI, Hba1c And Fasting Lipid Profile in Patients Presenting with Acute Coronary Syndrome and Their Relationship with CVD Risk","authors":"Gnanaguru Durairaj, Akash Thomas Oommen, G. Pillai","doi":"10.5530/JCDR.2019.1.12","DOIUrl":"https://doi.org/10.5530/JCDR.2019.1.12","url":null,"abstract":"It has been seen that among all the disease, worldwide, cardiovascular diseases (CVD) are among those that are the leading causes of mortality and morbidity with a prevalence that is seen to be increasing day by day. The incidence of this symptomatic CAD is exerting a negative effect on the quality of life and healthcare economics. Thus, there is an increase in the awareness of underlying causes of CVD, as well as improvements in treatment of atherosclerosis which has now resulted in a shift in focus from treatment to prevention of Symptomatic CVD. Hence, the recognition of those at risk of developing CAD and subsequent events is essential in the prevention strategies.1","PeriodicalId":15222,"journal":{"name":"Journal of Cardiovascular Disease Research","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-07-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46406331","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Asymptomatic Bilateral Internal Carotid Artery Occlusion Associated with Stenosis of the Right External Carotid Artery: Case Report","authors":"F. Hattab, F. Radi, L. Hara, E. Hafidi, J. Zarzur, M. Cherti","doi":"10.5530/JCDR.2019.2.15","DOIUrl":"https://doi.org/10.5530/JCDR.2019.2.15","url":null,"abstract":"Background: Bilateral Internal Carotid Artery Occlusion (BICAO) is an extremely rare pathological entity which have grave prognosis. It is responsible for 0.4% of completed strokes. Asymptomatic BICAO remains exceptional. Case report: We present a case of a 72-year-old man with asymptomatic bilateral internal carotid artery occlusion associated with stenosis of the right external carotid artery. Discussion: Therapeutic abstention was indicated given the absence of symptoms and the advanced age of our patient. Due to the limited cases reported in the literature whose therapeutic outcomes are controversial, the proper management strategy of BICAO remains unclear. Conclusion: We concluded that the increase in the number of reported cases, preferably series with large sample, as well as a long-term follow up for these patients will allow for a better evaluation of each therapeutic decision select.","PeriodicalId":15222,"journal":{"name":"Journal of Cardiovascular Disease Research","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-07-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44052237","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Invasive Assessment of Central Aortic Blood Pressure, Differential Impact of Beta Blocker vs. Non-Beta Blockers and their Correlation with Severity of Coronary Artery Disease in Hypertensive Patients Undergoing Coronary Angiography","authors":"S. Behera, A. Pradhan, R. Sethi, R. Saran, V. Narain, S. Dwivedi, S. Chandra","doi":"10.5530/JCDR.2019.1.4","DOIUrl":"https://doi.org/10.5530/JCDR.2019.1.4","url":null,"abstract":"Background: Non-invasively measured brachial arterial pressure is accepted as the standard method for blood pressure measurement. However, systolic pressure varies throughout the arterial tree such that central systolic pressure is actually lower than corresponding brachial pressure. The aim of the study was to evaluate the differential effects of commonly used antihypertensive drugs on central aortic pressure measured invasively. Methods and Results: This was a prospective, single-centre and observational study. During the time period November 2009 to November 2010, a total of 170 patients with chronic stable angina and systemic hypertension were enrolled. Detailed medical history and physical examinations were performed. Laboratory investigations were noted. Brachial and central aortic pressures were recorded and compared. Demographic and clinical parameters were comparable among patients in different antihypertensive therapy groups. Mean systolic blood pressure (SBP) difference and mean pulse pressure (PP) ratio values between beta blocker and non-beta blocker groups were significantly different, (p<0.0001) and (p=<0.0001) respectively. Mean central SBP difference and mean pulse pressure ratio values between beta blocker arm and beta blocker combination groups arm were significantly different too, (p <0.0001 and p=0.0005 respectively). Mean SBP difference and mean PP ratio were also significantly different for beta blocker monotherapy as compared with non-beta blocker drugs individually. In each antihypertensive therapy group, moderate and severe coronary artery disease groups had significantly higher central PP levels. Conclusion: Different classes of antihypertensives have differential impact on central blood pressures. Central systolic and pulse pressures cannot be inferred accurately from brachial blood pressures. Thus, there is potential for under treatment or overtreatment of hypertension based on brachial blood pressure targets.","PeriodicalId":15222,"journal":{"name":"Journal of Cardiovascular Disease Research","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-04-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47596107","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Quality of Life and its Predictors in Hospitalized Patients with Heart Failure at Hospitals Affiliated to Kermanshah-Iran University of Medical Sciences","authors":"S. Poorshadan, M. Fallahi, A. Abdi, Somayeh Mahdavikian, Javad Miri, H. Azami","doi":"10.5530/JCDR.2019.1.3","DOIUrl":"https://doi.org/10.5530/JCDR.2019.1.3","url":null,"abstract":"","PeriodicalId":15222,"journal":{"name":"Journal of Cardiovascular Disease Research","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-04-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42532502","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}