Lucia D Beissel, Fabian Kording, Christian Ruprecht, Alexander Isaak, Thomas M Vollbrecht, Claus C Pieper, Daniel Kuetting, Abdulamir Ali, Pia Wölfl, Christopher Hart, Julian A Luetkens
{"title":"Doppler Ultrasound Gating for Adult Cardiovascular Magnetic Resonance: Initial Experience.","authors":"Lucia D Beissel, Fabian Kording, Christian Ruprecht, Alexander Isaak, Thomas M Vollbrecht, Claus C Pieper, Daniel Kuetting, Abdulamir Ali, Pia Wölfl, Christopher Hart, Julian A Luetkens","doi":"10.1016/j.jocmr.2025.101862","DOIUrl":"https://doi.org/10.1016/j.jocmr.2025.101862","url":null,"abstract":"<p><strong>Background: </strong>Despite of being a common gating method for cardiovascular magnetic resonance (CMR), electrocardiogram (ECG) gating has its disadvantages and new gating strategies are desirable. An alternative CMR gating method is doppler ultrasound (DUS) gating, which detects blood flow and ventricular movement. The aim of this study was to prove the feasibility of DUS gating as a novel CMR gating method in a clinical patient population.</p><p><strong>Methods: </strong>In this prospective study, patients underwent clinically indicated CMR. Balanced steady-state free precession two-dimensional (2D) cine sequences in short axis and 4-chamber views were acquired using ECG and DUS gating. DUS and ECG signal were recorded simultaneously. Time difference between R wave and DUS systolic trigger detection was defined as trigger delay, the standard deviation of trigger delays as trigger jitter. Left and right ventricular parameters were assessed: Left and right ventricular ejection fraction (LVEF, RVEF) and left and right ventricular end-diastolic volume index (LVEDVI, RVEDVI). Overall image quality was assessed using a 5-point Likert scale (5=excellent to 1=non-diagnostic). For statistical analysis, paired t-test, Wilcoxon test, Pearson Correlation and intraclass correlation coefficient (ICC) were employed.</p><p><strong>Results: </strong>21 patients (7 female) were included (age: 45.4±19.7 years; body mass index: 27.6±5.5kg/m<sup>2</sup>). DUS mean trigger delay was 128±28ms. DUS mean trigger jitter was 23±13ms. Overall image quality showed no difference between ECG and DUS gating (e.g., short axis: 5 [IQR 3-5] vs. 4 [IQR 3.5-5]; P=0.21). Quantitative analysis revealed no differences between ECG and DUS gating: LVEF (53.2±9.2% vs. 52.3±9.1%; P=0.18; ICC 0.97 [95% confidence interval [CI] 0.93-0.99]), LVEDVI (84.5±15.8ml/m<sup>2</sup> vs. 83.3±15.8ml/m<sup>2</sup>; P=0.06; ICC 0.99 [95% CI 0.98-1.00]), RVEF (52.8±8.0% vs. 51.6±7.2%; P=0.06; ICC 0.96 [95% CI 0.89-0.99]) and RVEDVI (80.8±17.6ml/m<sup>2</sup> vs. 80.9±16.5ml/m<sup>2</sup>; P=0.91; ICC 0.98 [95% CI 0.96-0.99]). In one patient with a prominent lingula of the lung image quality non-diagnostic with DUS gating.</p><p><strong>Conclusion: </strong>CMR gating with DUS is feasible and can offer an equivalent performance to ECG regarding image quality and quantitative parameter assessment.</p>","PeriodicalId":15221,"journal":{"name":"Journal of Cardiovascular Magnetic Resonance","volume":" ","pages":"101862"},"PeriodicalIF":4.2,"publicationDate":"2025-02-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143425472","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Late Gadolinium-Enhanced Cardiac Magnetic Resonance for Predicting Left Ventricular Reverse Remodeling in Dilated Cardiomyopathy A Comprehensive Review and Meta-Analysis.","authors":"Yaqiong Zhou, Yuanwei Xu, Yangjie Li, Chuang Huang, Yucheng Chen","doi":"10.1016/j.jocmr.2025.101860","DOIUrl":"https://doi.org/10.1016/j.jocmr.2025.101860","url":null,"abstract":"<p><strong>Background: </strong>There is currently a lack of evidence regarding the significance of late gadolinium enhancement (LGE) on cardiac magnetic resonance (CMR) in predicting left ventricular (LV) reverse remodeling (RR) in pooled data. This study aimed to evaluate the predictive value of the presence and extent of LGE for LVRR in patients with dilated cardiomyopathy (DCM).</p><p><strong>Methods: </strong>Systematic searches were conducted in PubMed, Embase, Cochrane Library, and ClinicalTrials.gov from database inception to May 21, 2024. We estimated the overall effect sizes using the Mantel-Haenszel random-effects model. Subgroup analyses, meta-regression, and sensitivity analyses were performed to investigate potential sources of heterogeneity among studies.</p><p><strong>Results: </strong>A total of 1141 patients (LGE prevalence: 49.7%) from 13 studies (five prospective and eight retrospective) were included. After a median follow-up period of 15 months, 43.5% of patients achieved LVRR. The presence of LGE predicted LVRR with a pooled odds ratio (OR) of 0.23 (95% confidence interval [CI]: 0.14-0.38, P<0.01) with significant heterogeneity (I² = 68%). The pooled OR for LVRR per percent increase in the extent of LGE was 0.94 (95% CI: 0.90-0.98, P<0.01) with low heterogeneity (I² = 19%). Subgroup analysis based on follow-up duration demonstrated that the presence of LGE was more strongly inversely associated with LVRR in <12 months follow-up (OR 0.06, 95% CI: 0.03-0.13, P<0.01) compared to ≥ 12 months follow-up (OR 0.36, 95% CI: 0.24-0.54, P<0.01).</p><p><strong>Conclusion: </strong>The presence and increase extent of LGE on CMR significantly diminish LVRR achievement in DCM patients, particularly in short-term follow-up (<12 months).</p>","PeriodicalId":15221,"journal":{"name":"Journal of Cardiovascular Magnetic Resonance","volume":" ","pages":"101860"},"PeriodicalIF":4.2,"publicationDate":"2025-02-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143425413","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Josefin Obergassel, Michael Bietenbeck, Nuriye Akyol, Volker Vehof, Claudia Meier, Maria Theofanidou, Philipp Stalling, Ali Yilmaz
{"title":"Diagnostic value of bone scintigraphy versus cardiovascular magnetic resonance in cardiac amyloidosis.","authors":"Josefin Obergassel, Michael Bietenbeck, Nuriye Akyol, Volker Vehof, Claudia Meier, Maria Theofanidou, Philipp Stalling, Ali Yilmaz","doi":"10.1016/j.jocmr.2025.101859","DOIUrl":"10.1016/j.jocmr.2025.101859","url":null,"abstract":"<p><strong>Background: </strong>Accurate diagnosis of transthyretin amyloidosis cardiomyopathy (ATTR-CM) and its differentiation from light-chain (AL) cardiac amyloidosis (CA) cases (AL-CM) are of paramount importance. Surprisingly, comparative imaging data based on concurrent cardiovascular magnetic resonance (CMR) and bone scintigraphy in the same patients with biopsy-proven diagnosis of CA are still rare.</p><p><strong>Methods: </strong>This was a real-world retrospective single-center study based on a local clinical care pipeline and we carefully analyzed clinical, laboratory, CMR, and bone scintigraphy data (and if necessary additional endomyocardial biopsy [EMB] data) in patients with suspected CA. As a major inclusion criterion, we only looked at those patients who underwent both a CMR study and a bone scintigraphy-with a clear-cut imaging finding detected by at least one imaging method.</p><p><strong>Results: </strong>One hundred twenty three patients in whom the final diagnosis was obtained either non-invasively based on combined findings from bone scintigraphy and monoclonal protein studies or invasively based on additional EMB findings were included. A positive CMR result indicating the presence of CA was found in 121 patients-suggesting a CMR sensitivity of 98.4% for the diagnosis of any CA. Bone scintigraphy identified 18 patients with low to moderate uptake (Perugini score = 0-1) and 105 patients with high uptake (Perugini score ≥2)-resulting in a sensitivity for bone scintigraphy of 85.4% for the diagnosis of any CA. There was an agreement (\"diagnostic match\") between CMR and bone scintigraphy results in 103 patients (84%) of the total study cohort, while a discrepancy (\"diagnostic mismatch\") was observed in 20 patients (16%). In 18 out of these 20 diagnostic mismatch cases, CMR correctly diagnosed the presence of CA despite a negative or inconclusive result on bone scintigraphy (8 with AL-CM, 8 with ATTR-CM, and 2 with EMB-proven but unspecified CA).</p><p><strong>Conclusion: </strong>CMR shows a substantially higher diagnostic yield for the diagnosis of CA compared to bone scintigraphy, if a real-world cohort of patients comprising different subtypes of CA is looked at, since CMR does not only detect ATTR-CM but also depicts other CA subtypes such as AL. In case of a clear-cut positive CMR result unequivocally indicative of CA, there is no incremental diagnostic value of an additionally performed bone scintigraphy.</p>","PeriodicalId":15221,"journal":{"name":"Journal of Cardiovascular Magnetic Resonance","volume":" ","pages":"101859"},"PeriodicalIF":4.2,"publicationDate":"2025-02-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143425469","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Elizabeth W Thompson, Ningiun J Dong, Jin-Seo Kim, Abhijit Bhattaru, Phuong Vu, Fengling Hu, Russell T Shinohara, Sophia Swago, Elizabeth Donnelly, Xuemei Zhang, Annefleur Loth, Lipika Vuthuri, Kristen Lanzilotta, Kevin K Whitehead, Jeffrey Duda, James Gee, Laura Almasy, Elizabeth Goldmuntz, Mark A Fogel, Walter R Witschey
{"title":"Cardiovascular magnetic resonance imaging traits associated with adverse right ventricular remodeling in repaired tetralogy of Fallot: A Single Center Outcomes Using cardiovascular magnetic resonance in Tetralogy of Fallot study.","authors":"Elizabeth W Thompson, Ningiun J Dong, Jin-Seo Kim, Abhijit Bhattaru, Phuong Vu, Fengling Hu, Russell T Shinohara, Sophia Swago, Elizabeth Donnelly, Xuemei Zhang, Annefleur Loth, Lipika Vuthuri, Kristen Lanzilotta, Kevin K Whitehead, Jeffrey Duda, James Gee, Laura Almasy, Elizabeth Goldmuntz, Mark A Fogel, Walter R Witschey","doi":"10.1016/j.jocmr.2025.101855","DOIUrl":"10.1016/j.jocmr.2025.101855","url":null,"abstract":"<p><strong>Background: </strong>Deterioration of right ventricular (RV) function in repaired tetralogy of Fallot (rToF) is poorly understood. Cardiovascular magnetic resonance (CMR) is used for monitoring, but its analysis is user-dependent and time-consuming. We sought to automate the analysis of CMR using machine learning and to identify imaging traits associated with adverse RV remodeling in the natural history of rToF.</p><p><strong>Methods: </strong>A longitudinal cohort of rToF patients underwent CMR at the Children's Hospital of Philadelphia. The nnU-Net method was used to train a machine learning model to segment the left ventricular (LV) blood pool, LV myocardium, and RV blood pool from two-dimensional short-axis CMR images. Conventional and novel measures were calculated and studied in association with remodeling rates using multivariable linear regression. Remodeling rates were calculated as ((Variable<sub>scan2</sub> - Variable<sub>scan1</sub>)/years between scans) for the variables end-diastolic volume index (EDVi), end-systolic volume index (ESVi), stroke volume index (SVi), ejection fraction (EF), and peak systolic dV/dt.</p><p><strong>Results: </strong>The cohort was comprised of 758 patients, of whom 152 had 2 analyzable scans. Thirty-six patients underwent pulmonic valve replacement (PVR) between scans. Compared to patients with no intervention (representing the natural history of rToF), patients with PVR had significantly lower remodeling rates for RVEDVi, RVESVi, RVSVi, and absolute peak systolic RV dV/dt, while RVEF and left-sided metrics did not differ between groups. In 116 patients without PVR between scans, RV remodeling rates were negatively associated with baseline LV mass index, LVEDVi, LVSVi, and absolute peak systolic LV dV/dt.</p><p><strong>Conclusion: </strong>We demonstrated that rToF patients with two CMR scans and PVR have significant differences in and opposite directions of RV remodeling rates compared to those with no intervention. We also showed that several left-sided measures of structure and function were associated with RV remodeling rates, indicating the importance of baseline LV measurements in characterizing future risk of adverse RV remodeling.</p>","PeriodicalId":15221,"journal":{"name":"Journal of Cardiovascular Magnetic Resonance","volume":" ","pages":"101855"},"PeriodicalIF":4.2,"publicationDate":"2025-02-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143414435","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Aimee K Armstrong, Yixuan Liu, John M Kelly, Ramkumar Krishnamurthy, Jason Swinning, Yingmin Liu, Matthew Joseph, Ning Jin, Jianing Pang, Florian Maier, Axel J Krafft, Orville Bramwell, Nathan Ooms, Jesse Roll, Joshua Krieger, David C Gross, Lucien de Mos, Paul Borm, Orlando P Simonetti
{"title":"Feasibility of MRI-Guided Cardiac Catheterization, Angioplasty, and Stenting in a Commercial Wide-bore 0.55T Scanner.","authors":"Aimee K Armstrong, Yixuan Liu, John M Kelly, Ramkumar Krishnamurthy, Jason Swinning, Yingmin Liu, Matthew Joseph, Ning Jin, Jianing Pang, Florian Maier, Axel J Krafft, Orville Bramwell, Nathan Ooms, Jesse Roll, Joshua Krieger, David C Gross, Lucien de Mos, Paul Borm, Orlando P Simonetti","doi":"10.1016/j.jocmr.2025.101858","DOIUrl":"https://doi.org/10.1016/j.jocmr.2025.101858","url":null,"abstract":"<p><strong>Background: </strong>Low-field (0.55T) magnetic resonance imaging (MRI) may allow MRI-guided interventions using available catheterization equipment, as radiofrequency-induced heating of interventional devices is reduced at low field.</p><p><strong>Objective: </strong>The purpose of this study was to test the feasibility of real-time MRI-guided right and left heart catheterization (R&LHC) as well as angioplasty and stenting of the inferior vena cava using a commercially available 0.55T MRI system (MAGNETOM Free.Max, Siemens Healthineers AG, Erlangen, Germany) with 80cm patient bore and maximum gradient amplitude and slew rate of 26 mT/m and 45 mT/m/ms, respectively. A secondary aim was to evaluate three different sizes of MR-visible markers.</p><p><strong>Method: </strong>Sheaths were placed in the femoral vein and artery of juvenile Yorkshire pigs under general anesthesia. Air-filled balloon wedge catheters and Judkins Right catheters were used for R&LHC, respectively, aided by an MR-compatible guidewire. Ferumoxytol was administered as a T1-shortening contrast agent and real-time visualization was carried out with a research interactive sequence using different spatiotemporal resolution settings. Inferior vena cava (IVC) angioplasty was performed using balloons filled with 1% gadolinium, and IVC stenting was performed with stainless steel stents and one platinum iridium covered stent.</p><p><strong>Result: </strong>RHC was successful in all 8 attempts with balloon tip visibility in all real-time protocols. One pig expired with ferumoxytol infusion, but the catheterization was completed post-mortem. LHC and IVC angioplasty were attempted and successful in 2 and 4 pigs, respectively. For stenting, higher resolution, lower frame rate imaging was used. All 6 attempted stent implantations were successful. The MR markers on the angioplasty balloon with widths of 0.5 and 1mm were more visible than the 0.25mm markers. Marker placement affected distinguishability from the crimped stent. Stainless steel stents created only minimal signal voids pre- and post-deployment; however, the platinum-iridium stent caused significant artifact obscuring wall apposition assessment.</p><p><strong>Conclusion: </strong>This study is the first to demonstrate the technical feasibility of R&LHC, IVC angioplasty, and IVC stenting using real-time MRI on a commercially available low field scanner.</p>","PeriodicalId":15221,"journal":{"name":"Journal of Cardiovascular Magnetic Resonance","volume":" ","pages":"101858"},"PeriodicalIF":4.2,"publicationDate":"2025-02-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143407768","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Peirong Jiang, Lixin Liu, Xiuzhu Xu, Yanping Zheng, Jialin Chen, Huiyu Qiao, Lin Lin, Bin Sun, Xihai Zhao, He Wang, Zhensen Chen, Yunjing Xue
{"title":"Hemodynamics of distal cerebral arteries are associated with functional outcomes in symptomatic ischemic stroke in middle cerebral artery territory: A four-dimensional flow cardiovascular magnetic resonance study.","authors":"Peirong Jiang, Lixin Liu, Xiuzhu Xu, Yanping Zheng, Jialin Chen, Huiyu Qiao, Lin Lin, Bin Sun, Xihai Zhao, He Wang, Zhensen Chen, Yunjing Xue","doi":"10.1016/j.jocmr.2025.101857","DOIUrl":"10.1016/j.jocmr.2025.101857","url":null,"abstract":"<p><strong>Background: </strong>Cerebrovascular hemodynamics are believed to play an important role in the development of ischemic stroke (IS). However, the relationships between hemodynamics and prognosis are not fully understood. Four-dimensional (4D) flow cardiovascular magnetic resonance (CMR) enables comprehensive characteristics of cerebrovascular hemodynamics. This study aims to investigate the associations of the different hemodynamics derived from 4D flow CMR with IS functional outcomes.</p><p><strong>Methods: </strong>Ninety-one patients (median age 64 years, 62 males) with unilateral IS in middle cerebral artery (MCA) territory were included. All subjects underwent a CMR scan, including 4D flow, three-dimensional (3D) time-of-flight magnetic resonance angiography, and 3D whole brain black-blood high-resolution vessel wall imaging of the MCA. Six hemodynamic parameters, including flow rate, velocity, pulsatility index, time-averaged wall shear stress (TAWSS), oscillatory shear index, and relative residence time (RRT), were calculated for the lesion site, pre-bifurcation M1 (pM1) segment, and the distal M1 and/or first branches of M2 (dM1/M2) segments. Vessel characteristics, such as lumen area, vessel area, wall area, maximum wall thickness, and the degree of stenosis, were calculated at the most stenotic lesion site. The modified Rankin Scale (mRS) scores were assessed at 90 days and 1 year, and an mRS >2 was considered as a poor functional outcome.</p><p><strong>Results: </strong>Lower segment-level TAWSS (odds ratio [OR]: 0.24, P = 0.006 and OR: 0.29, P = 0.014), higher RRT (OR: 2.74, P = 0.007 and OR: 2.40, P = 0.011) of dM1/M2 segments, and lower segment- and lesion-level velocity (OR: 0.40, P = 0.019 and OR: 0.41, P = 0.025; OR: 0.41, P = 0.030 and OR: 0.42, P = 0.040) of pM1 segment were observed to be associated with poor functional outcome at both 90 days and 1 year. Using the cut-off value of 3.58 Pa and 0.29, respectively, TAWSS and RRT of dM1/M2 segments showed moderate performance in distinguishing poor functional outcome from favorable outcome (area under the curve ranging from 0.642-0.687) both at 90 days and 1 year.</p><p><strong>Conclusion: </strong>Distal segmental TAWSS and RRT of dM1/M2 segments were associated with poor functional outcomes. Such alterations in hemodynamics might help in the identification of patients with potentially unfavorable prognosis.</p>","PeriodicalId":15221,"journal":{"name":"Journal of Cardiovascular Magnetic Resonance","volume":" ","pages":"101857"},"PeriodicalIF":4.2,"publicationDate":"2025-02-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143407769","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Datta Singh Goolaub, Ye Tian, Joshua F P van Amerom, John Wood, Jon Detterich, Krishna S Nayak, Christopher K Macgowan
{"title":"Multiresolution comparison of fetal real-time and cine magnetic resonance imaging at 0.55T.","authors":"Datta Singh Goolaub, Ye Tian, Joshua F P van Amerom, John Wood, Jon Detterich, Krishna S Nayak, Christopher K Macgowan","doi":"10.1016/j.jocmr.2025.101856","DOIUrl":"10.1016/j.jocmr.2025.101856","url":null,"abstract":"<p><strong>Background: </strong>Dynamic fetal cardiovascular MRI (CMR) enables visualization of moving structures to assess congenital heart disease and plan treatment. Low field MRI systems can provide more comfortable platforms for fetal CMR. Here, we demonstrate the feasibility and utility of motion corrected fetal cardiac cine CMR and compare it with real-time CMR at multiple spatial resolutions at 0.55 T.</p><p><strong>Methods: </strong>Ten human pregnancies were scanned at 0.55T on a derated MAGNETOM Aera (Siemens Healthineers, Erlangen, Germany) with spiral steady-state free precession imaging. Real-time images were reconstructed and used for motion correction and fetal cardiac gating followed by cine reconstructions. The signal-to-noise ratio (SNR), image quality, blood-to-myocardium contrast, and contrast-to-noise ratio (CNR) from real-time and cine reconstructions were compared. The effect of acceleration on cine accuracy was assessed by retrospectively undersampling the data and measuring the reconstruction error with the normalized root-mean-squared difference (NRMSD) in five fetuses. Reproducibility of the measurements was assessed by reconstructing cines from two independent windows of data and computing the NRMSD relative to the reference image in five fetuses.</p><p><strong>Results: </strong>The SNR, CNR, and image quality were better for cines than their corresponding real-time reconstructions. The blood-to-myocardium contrast had no significant difference between real-time and cine reconstructions. With finer spatial resolution, real-time images degraded, and cardiac structures were less conspicuous. NRMSD in cines decreased with increasing scan times across all resolutions (NRMSD = 10 ± 2% for 7 s scan duration). Good consistency (NRMSD = 11 ± 3%) was achieved between independent reconstruction windows.</p><p><strong>Conclusion: </strong>While this study was performed on an experimental scanner (derated; not commercially available), we have shown that fetal cine CMR is feasible at 0.55T and provides high-quality fetal cardiac images at high spatiotemporal resolutions.</p>","PeriodicalId":15221,"journal":{"name":"Journal of Cardiovascular Magnetic Resonance","volume":" ","pages":"101856"},"PeriodicalIF":4.2,"publicationDate":"2025-02-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11968261/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143382582","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Jadranka Stojanovska, Robin Nijveldt, Karen Ordovas, Rozemarijn Vliegenthart, Nicole Seiberlich, Claudia Prieto, Vineeta Ojha, Kate Hanneman, Benny Lawton, Marina Hughes, Vanessa Ferreira, John Grizzard, Luigi Natale, Daniel Kim, Chiara Bucciarelli-Ducci, Steffen Petersen, Thomas A Treibel
{"title":"Highlights of the Cardiovascular Magnetic Resonance 2024 Conference: the first joint European Association of Cardiovascular Imaging, European Society of Cardiovascular Radiology, and Society for Cardiovascular Magnetic Resonance conference.","authors":"Jadranka Stojanovska, Robin Nijveldt, Karen Ordovas, Rozemarijn Vliegenthart, Nicole Seiberlich, Claudia Prieto, Vineeta Ojha, Kate Hanneman, Benny Lawton, Marina Hughes, Vanessa Ferreira, John Grizzard, Luigi Natale, Daniel Kim, Chiara Bucciarelli-Ducci, Steffen Petersen, Thomas A Treibel","doi":"10.1016/j.jocmr.2025.101848","DOIUrl":"https://doi.org/10.1016/j.jocmr.2025.101848","url":null,"abstract":"<p><p>Cardiovascular Magnetic Resonance 2024 Conference (CMR2024) convened in London, UK, from 24 to 26 January 2024 and brought together 2705 learners and renowned cardiac imaging professionals to discuss and learn about the latest advancements. Organized by the Society for Cardiovascular Magnetic Resonance (SCMR) and the European Association of Cardiovascular Imaging (EACVI), in collaboration with the European Society of Cardiovascular Radiology (ESCR), CMR2024 was the largest international cardiac magnetic resonance conference to date. This conference underscored the collaboration between cardiologists, radiologists, scientists, and technologists by bringing together three major societies-SCMR, EACVI, and ESCR. Innovative session formats like 'Shark Tank' and 'Workflow, Innovations & Patients' facilitated expert opinion and practical experiences sharing in a 'TED-talk style'. With over 1168 abstract submissions and 75% acceptance rate, the programme featured multiple Early Career Award sessions, oral scientific sessions, oral case sessions, and rapid-fire sessions, all categorized by topic. Highlights included patient- and physician-centred imaging sessions, sharing referring physicians' and patients' insights of incremental value of cardiovascular magnetic resonance (CMR) in patient's management. The programme offered invited lectures in eight parallel tracks with three plenary and two keynote speakers. In addition, the interactive workshops and panel discussions provided a platform for knowledge exchange, support, and collaboration. A great emphasis was placed on collaboration between radiologists, cardiologists, scientists, and technologists, showcasing an ideal cardiac imaging marriage as a model for enhanced patient care around the globe. The event also featured exhibitions of the latest CMR technology and software, offering attendees a glimpse into the future cardiac imaging. CMR2024 emerged as a remarkable scientific, educational, and networking event, in-spiring attendees to learn and collaborate within the global CMR community.</p>","PeriodicalId":15221,"journal":{"name":"Journal of Cardiovascular Magnetic Resonance","volume":" ","pages":"101848"},"PeriodicalIF":4.2,"publicationDate":"2025-02-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143414113","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ludovica Romanin, Milan Prsa, Christopher W Roy, Xavier Sieber, Jérôme Yerly, Bastien Milani, Tobias Rutz, Salim Si-Mohamed, Estelle Tenisch, Davide Piccini, Matthias Stuber
{"title":"Exploring the limits of scan time reduction for ferumoxytol-enhanced whole-heart angiography in congenital heart disease patients.","authors":"Ludovica Romanin, Milan Prsa, Christopher W Roy, Xavier Sieber, Jérôme Yerly, Bastien Milani, Tobias Rutz, Salim Si-Mohamed, Estelle Tenisch, Davide Piccini, Matthias Stuber","doi":"10.1016/j.jocmr.2025.101854","DOIUrl":"10.1016/j.jocmr.2025.101854","url":null,"abstract":"<p><strong>Background: </strong>One major challenge in cardiovascular magnetic resonance is reducing scan times to be more compatible with clinical workflows. In 3D magnetic resonance imaging (MRI), strategies to shorten scan times mostly rely on ECG-triggering or self-navigation for motion management, but are affected by heart rate variabilities or respiratory drifts. A similarity-driven multi-dimensional binning algorithm (SIMBA) was introduced for 3D whole-heart angiography from ferumoxytol-enhanced free-running MRI. This study explores acceleration limits using SIMBA, and its compressed-sensing extension extra-dimensional motion-compensation (XD-MC)-SIMBA, while preserving image quality.</p><p><strong>Methods: </strong>Data from 6-min free-running acquisitions of 30 congenital heart disease (CHD) patients were retrospectively undersampled to simulate 5-, 4-, 3-, 2-, and 1-min datasets. SIMBA and XD-MC-SIMBA reconstructions were applied. and the consistency of the data selection together with sharpness metrics were computed as a function of undersampling. Image quality was rated on a 5-point Likert scale. Shorter 3-minute acquisitions were prospectively acquired in nine CHD patients.</p><p><strong>Results: </strong>SIMBA's motion state selection was consistent across undersampling levels, with only 2 of 30 cases showing completely different selections. Image quality metrics decreased with increased undersampling, with SIMBA scoring lower compared to XD-MC-SIMBA. The diagnostic quality was good, with lower scores for 2- and 1-min datasets. Using XD-MC-SIMBA, 43% (31/72) of cases showed improved scores compared to SIMBA and 58% (7/12) of 1-min datasets improved to good or excellent quality.</p><p><strong>Conclusions: </strong>This study demonstrates that ferumoxytol-enhanced free-running MRI can be highly accelerated for 3D angiography in CHD.With the aid of compressed sensing, XD-MC-SIMBA supports the acceleration down to 3 minutes or less.</p>","PeriodicalId":15221,"journal":{"name":"Journal of Cardiovascular Magnetic Resonance","volume":" ","pages":"101854"},"PeriodicalIF":4.2,"publicationDate":"2025-02-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11889962/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143373963","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Maurice Pradella, Mohammed S M Elbaz, Daniel C Lee, KyungPyo Hong, Rod S Passman, Eugene Kholmovski, Dana C Peters, Justin J Baraboo, Daniel A Herzka, Reza Nezafat, Robert R Edelman, Daniel Kim
{"title":"A comprehensive evaluation of the left atrium using cardiovascular magnetic resonance.","authors":"Maurice Pradella, Mohammed S M Elbaz, Daniel C Lee, KyungPyo Hong, Rod S Passman, Eugene Kholmovski, Dana C Peters, Justin J Baraboo, Daniel A Herzka, Reza Nezafat, Robert R Edelman, Daniel Kim","doi":"10.1016/j.jocmr.2025.101852","DOIUrl":"10.1016/j.jocmr.2025.101852","url":null,"abstract":"<p><p>Atrial disease or myopathy is a growing concept in cardiovascular medicine, particularly in the context of atrial fibrillation, as well as amyloidosis and heart failure. Among cardiac imaging modalities, cardiovascular magnetic resonance (CMR) is particularly well suited for a comprehensive assessment of atrial myopathy, including tissue characterization and hemodynamics. The goal of this review article is to describe clinical applications and make recommendations on pulse sequences as well as imaging parameters to assess the left atrium and left atrial appendage. Furthermore, we aimed to create an overview of current and promising future emerging applications of left atrium-specific CMR pulse sequences focusing on both electrophysiologic (EP) and non-EP applications.</p>","PeriodicalId":15221,"journal":{"name":"Journal of Cardiovascular Magnetic Resonance","volume":" ","pages":"101852"},"PeriodicalIF":4.2,"publicationDate":"2025-02-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11889362/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143373827","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}