Journal of Cardiovascular Magnetic Resonance最新文献

{"title":"Diffusion tensor magnetic resonance imaging of the heart: Now feasible on your neighborhood scanner.","authors":"David E Sosnovik, Daniel B Ennis","doi":"10.1016/j.jocmr.2024.101101","DOIUrl":"10.1016/j.jocmr.2024.101101","url":null,"abstract":"","PeriodicalId":15221,"journal":{"name":"Journal of Cardiovascular Magnetic Resonance","volume":" ","pages":"101101"},"PeriodicalIF":4.2,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11647480/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142347431","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Assessing aortic motion with automated 3D cine balanced steady state free precession cardiovascular magnetic resonance segmentation.","authors":"Renske Merton, Daan Bosshardt, Gustav J Strijkers, Aart J Nederveen, Eric M Schrauben, Pim van Ooij","doi":"10.1016/j.jocmr.2024.101089","DOIUrl":"10.1016/j.jocmr.2024.101089","url":null,"abstract":"<p><strong>Purpose: </strong>To apply a free-running three-dimensional (3D) cine balanced steady state free precession (bSSFP) cardiovascular magnetic resonance (CMR) framework in combination with artificial intelligence (AI) segmentations to quantify time-resolved aortic displacement, diameter and diameter change.</p><p><strong>Methods: </strong>In this prospective study, we implemented a free-running 3D cine bSSFP sequence with scan time of approximately 4 min facilitated by pseudo-spiral Cartesian undersampling and compressed-sensing reconstruction. Automated segmentation of the aorta in all cardiac timeframes was applied through the use of nnU-Net. Dynamic 3D motion maps were created for three repeated scans per volunteer, leading to the detailed quantification of aortic motion, as well as the measurement and change in diameter of the ascending aorta.</p><p><strong>Results: </strong>A total of 14 adult healthy volunteers (median age, 28 years (interquartile range [IQR]: 26.0-31.3), 6 females) were included. Automated segmentation compared to manual segmentation of the aorta test set showed a Dice score of 0.93 ± 0.02. The median (IQR) over all volunteers for the largest maximum and mean ascending aorta (AAo) displacement in the first scan was 13.0 (4.4) mm and 5.6 (2.4) mm, respectively. Peak mean diameter in the AAo was 25.9 (2.2) mm and peak mean diameter change was 1.4 (0.5) mm. The maximum individual variability over the three repeated scans of maximum and mean AAo displacement was 3.9 (1.6) mm and 2.2 (0.8) mm, respectively. The maximum individual variability of mean diameter and diameter change were 1.2 (0.5) mm and 0.9 (0.4) mm.</p><p><strong>Conclusion: </strong>A free-running 3D cine bSSFP CMR scan with a scan time of four minutes combined with an automated nnU-net segmentation consistently captured the aorta's cardiac motion-related 4D displacement, diameter, and diameter change.</p>","PeriodicalId":15221,"journal":{"name":"Journal of Cardiovascular Magnetic Resonance","volume":" ","pages":"101089"},"PeriodicalIF":4.2,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11615597/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142107824","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of myocarditis with a free-breathing three-dimensional isotropic whole-heart joint T1 and T2 mapping sequence.","authors":"Alina Hua, Carlos Velasco, Camila Munoz, Giorgia Milotta, Anastasia Fotaki, Filippo Bosio, Inka Granlund, Agata Sularz, Amedeo Chiribiri, Karl P Kunze, Rene Botnar, Claudia Prieto, Tevfik F Ismail","doi":"10.1016/j.jocmr.2024.101100","DOIUrl":"10.1016/j.jocmr.2024.101100","url":null,"abstract":"<p><strong>Background: </strong>The diagnosis of myocarditis by cardiovascular magnetic resonance (CMR) requires the use of T2 and T1 weighted imaging, ideally incorporating parametric mapping. Current two-dimensional (2D) mapping sequences are acquired sequentially and involve multiple breath-holds resulting in prolonged scan times and anisotropic image resolution. We developed an isotropic free-breathing three-dimensional (3D) whole-heart sequence that allows simultaneous T1 and T2 mapping and validated it in patients with suspected myocarditis.</p><p><strong>Methods: </strong>Eighteen healthy volunteers and 28 patients with suspected myocarditis underwent conventional 2D T1 and T2 mapping with whole-heart coverage and 3D joint T1/T2 mapping on a 1.5T scanner. Acquisition time, image quality, and diagnostic performance were compared. Qualitative analysis was performed using a 4-point Likert scale. Bland-Altman plots were used to assess the quantitative agreement between 2D and 3D sequences.</p><p><strong>Results: </strong>The 3D T1/T2 sequence was acquired in 8 min 26 s under free breathing, whereas 2D T1 and T2 sequences were acquired with breath-holds in 11 min 44 s (p = 0.0001). All 2D images were diagnostic. For 3D images, 89% (25/28) of T1 and 96% (27/28) of T2 images were diagnostic with no significant difference in the proportion of diagnostic images for the 3D and 2D T1 (p = 0.2482) and T2 maps (p = 1.0000). Systematic bias in T1 was noted with biases of 102, 115, and 152 ms for basal-apical segments, with a larger bias for higher T1 values. Good agreement between T2 values for 3D and 2D techniques was found (bias of 1.8, 3.9, and 3.6 ms for basal-apical segments). The sensitivity and specificity of the 3D sequence for diagnosing acute myocarditis were 74% (95% confidence interval [CI] 49%-91%) and 83% (36%-100%), respectively, with a c-statistic (95% CI) of 0.85 (0.79-0.91) and no statistically significant difference between the 2D and 3D sequences for the detection of acute myocarditis for T1 (p = 0.2207) or T2 (p = 1.0000).</p><p><strong>Conclusion: </strong>Free-breathing whole-heart 3D joint T1/T2 mapping was comparable to 2D mapping sequences with respect to diagnostic performance, but with the added advantages of free breathing and shorter scan times. Further work is required to address the bias noted at high T1 values, but this did not significantly impact diagnostic accuracy.</p>","PeriodicalId":15221,"journal":{"name":"Journal of Cardiovascular Magnetic Resonance","volume":" ","pages":"101100"},"PeriodicalIF":4.2,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11638600/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142288044","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Fetal cardiovascular magnetic resonance feature tracking myocardial strain analysis in congenital heart disease.","authors":"Thomas M Vollbrecht, Christopher Hart, Christoph Katemann, Alexander Isaak, Claus C Pieper, Daniel Kuetting, Ulrike Attenberger, Annegret Geipel, Brigitte Strizek, Julian A Luetkens","doi":"10.1016/j.jocmr.2024.101094","DOIUrl":"10.1016/j.jocmr.2024.101094","url":null,"abstract":"<p><strong>Background: </strong>Cardiovascular magnetic resonance (CMR) is an emerging imaging modality for assessing the anatomy and function of the fetal heart in congenital heart disease (CHD). This study aimed to evaluate myocardial strain using fetal CMR feature tracking (FT) in different subtypes of CHD.</p><p><strong>Methods: </strong>Fetal CMR FT analysis was retrospectively performed on four-chamber cine images acquired with Doppler ultrasound gating at 3T. Left ventricular (LV) global longitudinal strain (GLS), LV global radial strain (GRS), LV global longitudinal systolic strain rate, and right ventricular (RV) GLS were quantified using dedicated software optimized for fetal strain analysis. Analysis was performed in normal fetuses and different CHD subtypes (d-transposition of the great arteries [dTGA], hypoplastic left heart syndrome [HLHS], coarctation of the aorta [CoA], tetralogy of Fallot [TOF], RV-dominant atrioventricular septal defect [AVSD], and critical pulmonary stenosis or atresia [PS/PA]). Analysis of variance with Tukey post-hoc test was used for group comparisons.</p><p><strong>Results: </strong>A total of 60 fetuses were analyzed (8/60 (13%) without CHD, 52/60 (87%) with CHD). Myocardial strain was successfully assessed in 113/120 ventricles (94%). Compared to controls, LV GLS was significantly reduced in fetuses with HLHS (-18.6±2.7% vs -6.2±5.6%; p<0.001) and RV-dominant AVSD (-18.6±2.7% vs -7.7±5.0%; p = 0.003) and higher in fetuses with CoA (-18.6±2.7% vs -25.0±4.3%; p = 0.038). LV GRS was significantly reduced in fetuses with HLHS (25.7±7.5% vs 11.4±9.7%; p = 0.024). Compared to controls, RV GRS was significantly reduced in fetuses with PS/PA (-16.1±2.8% vs -8.3±4.2%; p = 0.007). Across all strain parameters, no significant differences were present between controls and fetuses diagnosed with dTGA and TOF.</p><p><strong>Conclusion: </strong>Fetal myocardial strain assessment with CMR FT in CHD is feasible. Distinct differences are present between various types of CHD, suggesting potential implications for clinical decision-making and prognostication in fetal CHD.</p>","PeriodicalId":15221,"journal":{"name":"Journal of Cardiovascular Magnetic Resonance","volume":" ","pages":"101094"},"PeriodicalIF":4.2,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11616042/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142288046","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Phase-contrast magnetic resonance angiography of foot at 5T ultra-high field strength 5T : Visualization of distal small vessels and enhancement by warm water immersion.","authors":"Zhang Shi, Hao Li, Xiyin Miao, Bei Wang, Dong Wang, He Wang, Mengsu Zeng","doi":"10.1016/j.jocmr.2024.101114","DOIUrl":"10.1016/j.jocmr.2024.101114","url":null,"abstract":"<p><strong>Background: </strong>Ultra-high field strength magnetic resonance has been proven to offer improved visualization of the distal intracranial vessels and branches, but its effectiveness for visualization of the peripheral vasculature has not been investigated. We aimed to assess the visualization of distal lower-extremity vessels using three-dimensional phase-contrast magnetic resonance angiography (3D PC-MRA) at 5T field strength in combination with warm water immersion (WWI).</p><p><strong>Methods: </strong>Participants were prospectively recruited and underwent 3T, and 5T 3D PC-MRA of the feet with and without WWI (water temperature between 40°C and 45°C for a duration of 10 minutes). Patients with suspected lower-extremity peripheral arterial disease underwent computed tomography angiography for lesion identification. Signal-to-noise ratio (SNR), subjective scoring, quantitative vessel segmentation, and flow velocity were performed to assess vessel visualization before and after WWI. Friedman's test was conducted to determine statistical significance.</p><p><strong>Results: </strong>Out of 30 participants (mean age, 46.2 ± 5.9; males, 20; lower-extremity vessel disease, 10), 900 vessel segments were available for evaluation. 5T images showed significantly higher scores for image quality and foot vessel visualization than 3T (all P < 0.05). WWI further improved the visualizing scores (percentage of score 3: 40.2% (193/480), 66.2% (318/480)), SNR (44.27 vs 67.78, P < 0.001), total branch count (151.92 ± 29.17 vs 225.63 ± 16.76; P < 0.001), and the flow velocity (0.72 ± 0.03 vs 0.48 ± 0.11 cm/s; P < 0.001).</p><p><strong>Conclusion: </strong>3D PC-MRA at 5T effectively visualizes foot vessels in patients with lower-extremity disease. Furthermore, WWI can significantly enhance the depiction of distal and small vessels.</p>","PeriodicalId":15221,"journal":{"name":"Journal of Cardiovascular Magnetic Resonance","volume":" ","pages":"101114"},"PeriodicalIF":4.2,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11652875/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142501118","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Simultaneous multislice cardiac multimapping based on locally low-rank and sparsity constraints.","authors":"Yixin Emu, Yinyin Chen, Zhuo Chen, Juan Gao, Jianmin Yuan, Hongfei Lu, Hang Jin, Chenxi Hu","doi":"10.1016/j.jocmr.2024.101125","DOIUrl":"10.1016/j.jocmr.2024.101125","url":null,"abstract":"<p><strong>Background: </strong>Although quantitative myocardial T1 and T2 mappings are clinically used to evaluate myocardial diseases, their application needs a minimum of six breath-holds to cover three short-axis slices. The purpose of this work is to simultaneously quantify multislice myocardial T1 and T2 across three short-axis slices in one breath-hold by combining simultaneous multislice (SMS) with multimapping.</p><p><strong>Methods: </strong>An SMS-Multimapping sequence with multiband radiofrequency (RF) excitations and Cartesian fast low-angle shot readouts was developed for data acquisition. When 3 slices are simultaneously acquired, the acceleration rate is around 12-fold, causing a highly ill-conditioned reconstruction problem. To mitigate image artifacts and noise caused by the ill-conditioning, a reconstruction algorithm based on locally low-rank and sparsity (LLRS) constraints was developed. Validation was performed in phantoms and in vivo imaging, with 20 healthy subjects and 4 patients, regarding regional mean, precision, and scan-rescan reproducibility.</p><p><strong>Results: </strong>The phantom imaging shows that SMS-Multimapping with locally low-rank (LLRS) accurately reconstructed multislice T1 and T2 maps despite a six-fold acceleration of scan time. Healthy subject imaging shows that the proposed LLRS algorithm substantially improved image quality relative to split slice-generalized autocalibrating partially parallel acquisition. Compared with modified look-locker inversion recovery (MOLLI), SMS-Multimapping exhibited higher T1 mean (1118 ± 43 ms vs 1190 ± 49 ms, P < 0.01), lower precision (67 ± 17 ms vs 90 ± 17 ms, P < 0.01), and acceptable scan-rescan reproducibility measured by 2 scans 10-min apart (bias = 1.4 ms for MOLLI and 9.0 ms for SMS-Multimapping). Compared with balanced steady-state free precession (bSSFP) T2 mapping, SMS-Multimapping exhibited similar T2 mean (43.5 ± 3.3 ms vs 43.0 ± 3.5 ms, P = 0.64), similar precision (4.9 ± 2.1 ms vs 5.1 ± 1.0 ms, P = 0.93), and acceptable scan-rescan reproducibility (bias = 0.13 ms for bSSFP T2 mapping and 0.55 ms for SMS-Multimapping). In patients, SMS-Multimapping clearly showed the abnormality in a similar fashion as the reference methods despite using only one breath-hold.</p><p><strong>Conclusion: </strong>SMS-Multimapping with the proposed LLRS reconstruction can measure multislice T1 and T2 maps in one breath-hold with good accuracy, reasonable precision, and acceptable reproducibility, achieving a six-fold reduction of scan time and an improvement of patient comfort.</p>","PeriodicalId":15221,"journal":{"name":"Journal of Cardiovascular Magnetic Resonance","volume":" ","pages":"101125"},"PeriodicalIF":4.2,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11663759/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142638737","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Association between subclinical right ventricular alterations and aerobic exercise capacity in type 2 diabetes.","authors":"Abhishek Dattani, Jian L Yeo, Emer M Brady, Alice Cowley, Anna-Marie Marsh, Manjit Sian, Joanna M Bilak, Matthew P M Graham-Brown, Anvesha Singh, Jayanth R Arnold, David Adlam, Thomas Yates, Gerry P McCann, Gaurav S Gulsin","doi":"10.1016/j.jocmr.2024.101120","DOIUrl":"10.1016/j.jocmr.2024.101120","url":null,"abstract":"<p><strong>Background: </strong>Type 2 diabetes (T2D) leads to cardiovascular remodeling, and heart failure has emerged as a major complication of T2D. There is a limited understanding of the impact of T2D on the right heart. This study aimed to assess subclinical right heart alterations and their contribution to aerobic exercise capacity (peak oxygen consumption; peak VO₂) in adults with T2D.</p><p><strong>Methods: </strong>Single center, prospective, case-control comparison of adults with and without T2D, and no prevalent cardiac disease. Comprehensive evaluation of the left and right heart was performed using transthoracic echocardiography and stress cardiovascular magnetic resonance. Cardiopulmonary exercise testing on a bicycle ergometer with expired gas analysis was performed to determine peak VO₂. Between group comparison was adjusted for age, sex, race, and body mass index using analysis of covariance (ANCOVA). Multivariable linear regression, including key clinical and left heart variables, was undertaken in people with T2D to identify independent associations between measures of right ventricular (RV) structure and function with peak VO₂.</p><p><strong>Results: </strong>Three hundred and forty people with T2D (median age 64years, 62% (211) male, mean glycated hemoglobin (HbA1c) 7.3%) and 66 controls (median age 58years, 58% (38) male, mean HbA1c 5.5%) were included. T2D participants had markedly lower peak VO₂ (adjusted mean 20.3 (95% confidence interval (CI): 19.8-20.9) vs 23.3(22.2-24.5)mL/kg/min, P < 0.001) than controls and had smaller left ventricular (LV) volumes and LV concentric remodeling. Those with T2D had smaller RV volumes (indexed RV end-diastolic volume: 84 (82-86) vs 100 (96-104)mL/m, P < 0.001) with evidence of hyperdynamic RV systolic function (global longitudinal strain (GLS): 26.3 (25.8-26.8) vs 23.5 (22.5-24.5)%, P < 0.001) and impaired RV relaxation (longitudinal peak early diastolic strain rate (PEDSR): 0.77 (0.74-0.80) vs 0.92 (0.85-1.00) s^-1, P < 0.001). Multivariable linear regression demonstrated that RV end-diastolic volume (β =-0.342, P = 0.004) and RV cardiac output (β = 0.296, P = 0.001), but not LV parameters, were independent determinants of peak VO₂.</p><p><strong>Conclusion: </strong>In T2D, markers of RV remodeling are associated with aerobic exercise capacity, independent of left heart alterations.</p>","PeriodicalId":15221,"journal":{"name":"Journal of Cardiovascular Magnetic Resonance","volume":" ","pages":"101120"},"PeriodicalIF":4.2,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11663768/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142545721","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Impact of valve-sparing aortic root replacement on aortic fluid dynamics and biomechanics in patients with syndromic heritable thoracic aortic disease.","authors":"Lydia Dux-Santoy, Aroa Ruiz-Muñoz, Andrea Guala, Laura Galian-Gay, Rubén Fernandez-Galera, Filipa Valente, Guillem Casas, Ruperto Oliveró, Marta Ferrer-Cornet, Mireia Bragulat-Arévalo, Alejandro Carrasco-Poves, Juan Garrido-Oliver, Alberto Morales-Galán, Kevin M Johnson, Oliver Wieben, Ignacio Ferreira-González, Arturo Evangelista, Jose Rodriguez-Palomares, Gisela Teixidó-Turà","doi":"10.1016/j.jocmr.2024.101088","DOIUrl":"10.1016/j.jocmr.2024.101088","url":null,"abstract":"<p><strong>Background: </strong>Patients with syndromic heritable thoracic aortic diseases (sHTAD) who underwent prophylactic aortic root replacement are at high risk of distal aortic events, but the underlying mechanisms remain unclear. This prospective, longitudinal study evaluates the impact of valve-sparing aortic root replacement (VSARR) on aortic fluid dynamics and biomechanics in these patients.</p><p><strong>Methods: </strong>Sixteen patients with Marfan or Loeys-Dietz syndrome underwent two time-resolved three-dimensional phase-contrast cardiovascular magnetic resonance (4D flow CMR) studies before (sHTAD-preSx) and after VSARR (sHTAD-postSx). Two matched cohorts of 40 healthy volunteers (HV) and 16 sHTAD patients without indication for aortic root replacement (sHTAD-NSx) with available 4D flow CMR were included for comparison. In-plane rotational flow (IRF), systolic flow reversal ratio (SFRR), wall shear stress (WSS), pulse wave velocity (PWV), and aortic strain were analyzed in the ascending (AscAo) and descending aorta (DescAo).</p><p><strong>Results: </strong>All patients with sHTAD presented altered hemodynamics and increased stiffness (p < 0.05) compared to HV, both in the AscAo (median PWV 7.4 in sHTAD-NSx; 6.8 in sHTAD-preSx; 4.9 m/s in HV) and DescAo (median PWV 9.1 in sHTAD-NSx; 8.1 in sHTAD-preSx; 6.3 m/s in HV). Patients awaiting VSARR had markedly reduced in-plane (median IRF -2.2 vs 10.4 cm²/s in HV, p = 0.001), but increased through-plane flow rotation (median SFRR 7.8 vs 3.8% in HV, p = 0.002), and decreased WSS (0.36 vs 0.47 N/m² in HV, p = 0.004) in the proximal DescAo. After VSARR, proximal DescAo IRF (p = 0.010) and circumferential WSS increased (p = 0.011), no longer differing from HV, but SFRR, axial WSS and stiffness remained altered. Patients in which aortic tortuosity was reduced after surgery showed greater post-surgical increase in IRF compared to those in which tortuosity increased (median IRF increase 18.1 vs 3.3 cm²/s, p = 0.047). Most AscAo flow alterations were restored to physiological values after VSARR.</p><p><strong>Conclusion: </strong>In patients with sHTAD, VSARR partially restores downstream fluid dynamics to physiological levels. However, some flow disturbances and increased stiffness persist in the proximal DescAo. Further longitudinal studies are needed to evaluate whether persistent alterations contribute to post-surgical risk.</p>","PeriodicalId":15221,"journal":{"name":"Journal of Cardiovascular Magnetic Resonance","volume":" ","pages":"101088"},"PeriodicalIF":4.2,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11616068/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142107825","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Accelerated chemical shift encoded cardiovascular magnetic resonance imaging with use of a resolution enhancement network.","authors":"Manuel A Morales, Scott Johnson, Patrick Pierce, Reza Nezafat","doi":"10.1016/j.jocmr.2024.101090","DOIUrl":"10.1016/j.jocmr.2024.101090","url":null,"abstract":"<p><strong>Background: </strong>Cardiovascular magnetic resonance (CMR) chemical shift encoding (CSE) enables myocardial fat imaging. We sought to develop a deep learning network (fast chemical shift encoding [FastCSE]) to accelerate CSE.</p><p><strong>Methods: </strong>FastCSE was built on a super-resolution generative adversarial network extended to enhance complex-valued image sharpness. FastCSE enhances each echo image independently before water-fat separation. FastCSE was trained with retrospectively identified cines from 1519 patients (56 ± 16 years; 866 men) referred for clinical 3T CMR. In a prospective study of 16 participants (58 ± 19 years; 7 females) and 5 healthy individuals (32 ± 17 years; 5 females), dual-echo CSE images were collected with 1.5 × 1.5 mm², 2.5 × 1.5 mm², and 3.8 × 1.9 mm² resolution using generalized autocalibrating partially parallel acquisition (GRAPPA). FastCSE was applied to images collected with resolution of 2.5 × 1.5 mm² and 3.8 × 1.9 mm² to restore sharpness. Fat images obtained from two-point Dixon reconstruction were evaluated using a quantitative blur metric and analyzed with a five-way analysis of variance.</p><p><strong>Results: </strong>FastCSE successfully reconstructed CSE images inline. FastCSE acquisition, with a resolution of 2.5 × 1.5 mm² and 3.8 × 1.9 mm², reduced the number of breath-holds without impacting visualization of fat by approximately 1.5-fold and 3-fold compared to GRAPPA acquisition with a resolution of 1.5 × 1.5 mm², from 3.0 ± 0.8 breath-holds to 2.0 ± 0.2 and 1.1 ± 0.4 breath-holds, respectively. FastCSE improved image sharpness and removed ringing artifacts in GRAPPA fat images acquired with a resolution of 2.5 × 1.5 mm² (0.32 ± 0.03 vs 0.35 ± 0.04, P < 0.001) and 3.8 × 1.9 mm² (0.32 ± 0.03 vs 0.43 ± 0.06, P < 0.001). Blurring in FastCSE images was similar to blurring in images with 1.5 × 1.5 mm² resolution (0.32 ± 0.03 vs 0.31 ± 0.03, P = 0.57; 0.32 ± 0.03 vs 0.31 ± 0.03, P = 0.66).</p><p><strong>Conclusion: </strong>We showed that a deep learning-accelerated CSE technique based on complex-valued resolution enhancement can reduce the number of breath-holds in CSE imaging without impacting the visualization of fat. FastCSE showed similar image sharpness compared to a standardized parallel imaging method.</p>","PeriodicalId":15221,"journal":{"name":"Journal of Cardiovascular Magnetic Resonance","volume":" ","pages":"101090"},"PeriodicalIF":4.2,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11612775/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142145724","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Thoracic duct drainage patterns in heterotaxy.","authors":"Daniel A Castellanos, Emily M Bucholz, Katherine Bai, Jesse J Esch, David Hoganson, Stephen P Sanders, Raja Shaikh, Sunil J Ghelani, David N Schidlow","doi":"10.1016/j.jocmr.2024.101050","DOIUrl":"10.1016/j.jocmr.2024.101050","url":null,"abstract":"<p><strong>Background: </strong>Disordered lymphatic drainage is common in congenital heart diseases (CHD), but thoracic duct (TD) drainage patterns in heterotaxy have not been described in detail. This study sought to describe terminal TD sidedness in heterotaxy and its associations with other anatomic variables.</p><p><strong>Methods: </strong>This was a retrospective, single-center study of patients with heterotaxy who underwent cardiovascular magnetic resonance imaging at a single center between July 1, 2019 and May 15, 2023. Patients with (1) asplenia (right isomerism), (2) polysplenia (left isomerism) and (3) pulmonary/abdominal situs inversus (PASI) plus CHD were included. Terminal TD sidedness was described as left-sided, right-sided, or bilateral.</p><p><strong>Results: </strong>Of 115 eligible patients, the terminal TD was visualized in 56 (49 %). The terminal TD was left-sided in 25 patients, right-sided in 29, and bilateral in two. On univariate analysis, terminal TD sidedness was associated with atrial situs (p = 0.006), abdominal situs (p = 0.042), type of heterotaxy (p = 0.036), the presence of pulmonary obstruction (p = 0.041), superior vena cava sidedness (p = 0.005), and arch sidedness (p < 0.001). On multivariable analysis, only superior vena cava and aortic arch sidedness were independently associated with terminal TD sidedness.</p><p><strong>Conclusions: </strong>Terminal TD sidedness is highly variable in patients with heterotaxy. Superior vena cava and arch sidedness are independently associated with terminal TD sidedness. Type of heterotaxy was not independently associated with terminal TD sidedness. This data improves the understanding of anatomic variation in patients with heterotaxy and may be useful for planning for lymphatic interventions.</p>","PeriodicalId":15221,"journal":{"name":"Journal of Cardiovascular Magnetic Resonance","volume":" ","pages":"101050"},"PeriodicalIF":4.2,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11283042/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141442760","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}