Journal of Biomimetics, Biomaterials and Tissue Engineering最新文献_第9页

Physico-Chemical Properties and Characterization of CaO-Fe2O3-P2O5 Glass as a Bioactive Ceramic Material 生物活性陶瓷材料CaO-Fe2O3-P2O5玻璃的理化性质及表征

Journal of Biomimetics, Biomaterials and Tissue Engineering Pub Date : 2012-01-31 DOI: 10.4028/www.scientific.net/JBBTE.12.1

M. R. Majhi, R. Kumar, S.P. Singh, R. Pyare

{"title":"Physico-Chemical Properties and Characterization of CaO-Fe2O3-P2O5 Glass as a Bioactive Ceramic Material","authors":"M. R. Majhi, R. Kumar, S.P. Singh, R. Pyare","doi":"10.4028/www.scientific.net/JBBTE.12.1","DOIUrl":"https://doi.org/10.4028/www.scientific.net/JBBTE.12.1","url":null,"abstract":"The Aim of this Work Is to Investigate Role of Iron in Calcium-Iron-Phosphate Bioglass. the Density, Compressive Strength, Tg Point and Leachability of Cations Were Measured. the Ph Behaviour of Simulated Body Fluid after Soaking Phosphate Glasses for Different Time Periods Were Also Studied and it Was Observed that Higher Phosphate Glasses Containing Lower Lime Possessed Better Bioactivity than Lower Phosphate Glasses Containing More Iron and Lime Contents. the DTA and FTIR Spectrometry of Glasses Were Performed. the Absorption Spectra Showed that Iron Was Present in the Glass only as Fe3+ Ion. the Leachability of Ca2+ and Fe3+ Ions from Glass Was due to Diffusion Control and P5+ Ion due to Network Break down of PO4 Tetrahedra. the DTA Peaks Were Broad. the FTIR Band around 1000 Cm-1 in Glass Was due to Asymmetric Stretching of O=P=O Linkage. the FTIR Absorption and Reflectance Spectrometry of the Glass Samples after SBF Treatment Had Confirmed the Deposition of Bone-Like Hydroxyl Carbonate Apatite Layer on the Glass Surfaces for their Bioactivity. the Bands Centred in between 2880-3425 Cm-1 Were due to Presence of OH Groups and Stretching Modes of H-O-H Vibration in Glasses. the Properties and Structure Relationship for Glasses Were Established and the Results Were Discussed.","PeriodicalId":15198,"journal":{"name":"Journal of Biomimetics, Biomaterials and Tissue Engineering","volume":"58 1","pages":"1 - 24"},"PeriodicalIF":0.0,"publicationDate":"2012-01-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83989246","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 6

Synthesis and Characterization of Sol-Gel Derived Hydroxyapatite-Bioglass Composite Nanopowders for Biomedical Applications 生物医学用溶胶-凝胶羟基磷灰石-生物玻璃复合纳米粉体的合成与表征

Journal of Biomimetics, Biomaterials and Tissue Engineering Pub Date : 2012-01-31 DOI: 10.4028/www.scientific.net/JBBTE.12.51

S. Adibnia, A. Nemati, M. Fathi, S. Baghshahi

{"title":"Synthesis and Characterization of Sol-Gel Derived Hydroxyapatite-Bioglass Composite Nanopowders for Biomedical Applications","authors":"S. Adibnia, A. Nemati, M. Fathi, S. Baghshahi","doi":"10.4028/www.scientific.net/JBBTE.12.51","DOIUrl":"https://doi.org/10.4028/www.scientific.net/JBBTE.12.51","url":null,"abstract":"The main purpose of this study is to prepare and characterize hydroxyapatite (HA)–10%wt bioglass (BG) composite nanopowders and its bioactivity. Composites of hydroxyapatite with synthesized bioglass are prepared at various temperatures. Suitable calcination temperature is chosen by evaluating of the phase composition. X-ray diffraction (XRD), Transmission electron microscopy (TEM) and Scanning electron microscopy (SEM) techniques are utilized to characterize the prepared nanopowders. The bioactivity of the prepared composite samples is evaluated in an in vitro study by immersion of samples in simulated body fluid (SBF) for predicted time. Fourier transformed infrared (FTIR) spectroscopy and inductively coupled plasma (ICP) are used for evaluation of apatite formation and the bioactivity properties. Results show that HA-BG composite nanopowders are successfully prepared without any decomposition of hydroxyapatite. The suitable temperature for calcination is 600°C and the particle size of hydroxyapatite is about 40-70 nm. The apatite phase forms after 14 days immersing of the samples in SBF. It could be concluded that this process can be used to synthesize HA-BG composite nanopowders with improved bioactivity which is much needed for hard tissue repair and biomedical applications.","PeriodicalId":15198,"journal":{"name":"Journal of Biomimetics, Biomaterials and Tissue Engineering","volume":"34 1","pages":"51 - 57"},"PeriodicalIF":0.0,"publicationDate":"2012-01-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78383125","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 5

Effect of Biomimetic Nanocrystalline Apatite Surface on Bone Ingrowth 仿生纳米磷灰石表面对骨长入的影响

Journal of Biomimetics, Biomaterials and Tissue Engineering Pub Date : 2012-01-31 DOI: 10.4028/www.scientific.net/JBBTE.12.41

J. Gelber, J. Hermida, S. Patil, C. Colwell, D. D’Lima

引用次数: 0

Finite Element Modelling of Rheological Property of Curing PMMA Bone Cement. Part 1 - Effect of Prosthesis Insertion Velocity 固化PMMA骨水泥流变特性的有限元模拟。第一部分-假体插入速度的影响

Journal of Biomimetics, Biomaterials and Tissue Engineering Pub Date : 2012-01-31 DOI: 10.4028/www.scientific.net/JBBTE.12.83

M.M. Rahman, A. Olabi, M. Hashmi

{"title":"Finite Element Modelling of Rheological Property of Curing PMMA Bone Cement. Part 1 - Effect of Prosthesis Insertion Velocity","authors":"M.M. Rahman, A. Olabi, M. Hashmi","doi":"10.4028/www.scientific.net/JBBTE.12.83","DOIUrl":"https://doi.org/10.4028/www.scientific.net/JBBTE.12.83","url":null,"abstract":"PMMA (Polymethyl methacrylate) bone cement is currently the only material used for anchoring cemented arthroplasties to contiguous bones. The aim of this work is to model the flow of bone cement through porous cancellous bone to study the degree of penetration in total hip replacement using FIDAP simulation software. Two different viscosity models have been used (a) power law with constant consistency index and power law index less than 1 for pseudoplastic behaviour of Simplex P® and Zimmer bone cement; (b) FORTRAN subroutine for time dependent rheopectic behaviour of CMW3 and Zimmer bone cement. For each type of bone cement the effect of prosthesis insertion velocity have been investigated under four different values 5, 10, 15 and 20 mm/s. It has been observed that the depth of penetration increases with increasing prosthesis insertion velocity. On the other hand, the maximum pressure in bone cement decreases with increasing prosthesis insertion velocity. It has been observed that there is more penetration through cancellous bone for pseudoplastic behaviour than rheopectic behaviour of bone cement.","PeriodicalId":15198,"journal":{"name":"Journal of Biomimetics, Biomaterials and Tissue Engineering","volume":"103 1","pages":"83 - 90"},"PeriodicalIF":0.0,"publicationDate":"2012-01-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81627195","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

An Investigation of the Carriage Rate of Methicillin-Resistant Staphylococcus aureus in Pigs in the Western Province of Vietnam 越南西部省猪群耐甲氧西林金黄色葡萄球菌携带率调查

Journal of Biomimetics, Biomaterials and Tissue Engineering Pub Date : 2012-01-31 DOI: 10.4028/www.scientific.net/JBBTE.12.91

T. Vo, An Doan Mai Huynh, H. Ngo, D. T. Nguyen, Thi Minh Tam Tran

{"title":"An Investigation of the Carriage Rate of Methicillin-Resistant Staphylococcus aureus in Pigs in the Western Province of Vietnam","authors":"T. Vo, An Doan Mai Huynh, H. Ngo, D. T. Nguyen, Thi Minh Tam Tran","doi":"10.4028/www.scientific.net/JBBTE.12.91","DOIUrl":"https://doi.org/10.4028/www.scientific.net/JBBTE.12.91","url":null,"abstract":"Methicillin-resistant Staphylococcus aureus (MRSA) transmission between pigs and humans can be a dangerous infection source for the community. To control and prevent such disease, MRSA research in healthy pigs has been conducted in the US and Holland. This paper reports the first such study in Vietnam. This study aims to optimize the method for investigating MRSA carriage in tonsil and nasal swabs of healthy pigs. Potential samples were selected rapidly by Multiplex PCR (M-PCR) assay with 3 primers (Staph 756, mecA, Sa442) and then combined with conventional methods to detect and pick up MRSA strains. These strains were grouped based on genome pattern by pulsed field gel electrophoresis (PFGE). This study showed that we successfully isolated MRSA and the rate of MRSA carriage samples was 3.63%, much lower than that reported in the USA (49%) and Holland (39%), however the USA and Holland studies investigated pigs from industrial scale piggeries, whereas our study investigated pigs from small farms, which is the usual approach to pig farming in Vietnam. The MRSA patterns identified and associated MRSA strains were different from identified MRSA strains in other countries. This research provides important information about the carriage rate of MRSA in pigs in the Western province of Vietnam and demonstrates the importance of ongoing investigations in this area.","PeriodicalId":15198,"journal":{"name":"Journal of Biomimetics, Biomaterials and Tissue Engineering","volume":"23 1","pages":"91 - 98"},"PeriodicalIF":0.0,"publicationDate":"2012-01-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78183084","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

Osteocyte Characterization on Polydimethylsiloxane Substrates for Microsystems Applications. 用于微系统应用的聚二甲基硅氧烷基底上的骨细胞特征描述

Journal of Biomimetics, Biomaterials and Tissue Engineering Pub Date : 2012-01-01 DOI: 10.4028/www.scientific.net/JBBTE.16.27

Spencer L York, Ahmad R Arida, Karan S Shah, Palaniappan Sethu, Marnie M Saunders

{"title":"Osteocyte Characterization on Polydimethylsiloxane Substrates for Microsystems Applications.","authors":"Spencer L York, Ahmad R Arida, Karan S Shah, Palaniappan Sethu, Marnie M Saunders","doi":"10.4028/www.scientific.net/JBBTE.16.27","DOIUrl":"10.4028/www.scientific.net/JBBTE.16.27","url":null,"abstract":"In the body, osteocytes reside in lacunae, lenticular shaped cavities within mineralized bone. These cells are linked to each other and surface-residing osteoblasts via physical channels known as gap junctions. It has been suggested that osteocytes sense mechanical load applied to bone and relay that signal to osteoclasts and osteoblasts. Current in vitro and in vivo models of mechanotransduction face temporal and spatial barriers. Recent advances in polydimethylsiloxane (PDMS) based microfabrication techniques may be able to overcome some of these hurdles. However, before the bone research field can effectively utilize microsystems techniques, fundamental groundwork must be completed. This study characterized the behaviour of osteocytes on PDMS coated with collagen type I (CTI) and provides the framework for bone cell mechanotransduction studies using microsystems. The goal was to determine whether osteocytes were adversely affected by the substrate material by comparing their behaviour to a standard glass substrate. In addition, optimal culture conditions and time points for growing osteocytes on PDMS substrates were determined. Results of this study suggested that use of PDMS does not adversely affect osteocyte behaviour. Furthermore, the results demonstrated that osteocytes should be cultured for no less than 72 hours prior to experimentation to allow the establishment and maintenance of phenotypic characteristics. These results completed essential groundwork necessary for further studies regarding osteocytes in microsystems modelling utilizing PDMS.","PeriodicalId":15198,"journal":{"name":"Journal of Biomimetics, Biomaterials and Tissue Engineering","volume":"16 ","pages":"27-42"},"PeriodicalIF":0.0,"publicationDate":"2012-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6150457/pdf/nihms905282.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36517590","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Sequential Release of BMP-7 and VEGF from the PLGA/AK-Gelatin Composite Scaffolds BMP-7和VEGF在PLGA/ ak -明胶复合支架中的顺序释放

Journal of Biomimetics, Biomaterials and Tissue Engineering Pub Date : 2011-09-01 DOI: 10.4028/www.scientific.net/JBBTE.11.81

Gang Liu, W. Fan, X. Miao, Yin Xiao, David Good, M. Wei

{"title":"Sequential Release of BMP-7 and VEGF from the PLGA/AK-Gelatin Composite Scaffolds","authors":"Gang Liu, W. Fan, X. Miao, Yin Xiao, David Good, M. Wei","doi":"10.4028/www.scientific.net/JBBTE.11.81","DOIUrl":"https://doi.org/10.4028/www.scientific.net/JBBTE.11.81","url":null,"abstract":"Vascular endothelial growth factor (VEGF) and bone morphogenetic proteins (BMP-7) are key regulators of angiogenesis and osteogenesis during bone regeneration. The aim of this study was to investigate the possibility of realizing sequential release of the two growth factors using a novel composite scaffold. Poly(lactic-co-glycolic acid) (PLGA)-Akermanite (AK) microspheres were used to make the composite scaffold, which was then loaded with BMP-7, followed by embedding in a gelatin hydrogel matrix loaded with VEGF. The release profiles of the growth factors were studied and selected osteogenic related markers of bone marrow stromal cells (BMSCs) were analysed. It was shown that the composite scaffolds exhibited a fast initial burst release of VEGF within the first 3 days and a sustained slow release of BMP-7 over the full period of 20 days. The in vitro proliferation and differentiation of the BMSCs cultured in the osteogenic medium were enhanced by 1 to 2 times, resulting from the additionally and sequentially release of growth factors from the PLGA-AK/gelatin composite scaffolds.","PeriodicalId":15198,"journal":{"name":"Journal of Biomimetics, Biomaterials and Tissue Engineering","volume":"31 1","pages":"81 - 91"},"PeriodicalIF":0.0,"publicationDate":"2011-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74723966","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

A Method to Fabricate Liver Tissue Engineering Scaffold 一种制备肝组织工程支架的方法

Journal of Biomimetics, Biomaterials and Tissue Engineering Pub Date : 2011-09-01 DOI: 10.4028/www.scientific.net/JBBTE.11.73

S. Singare, S. Zhong, Z. Sun

引用次数: 3

Preparation and Characterization of CaF2 Doped Bioglass Ceramics 掺CaF2生物玻璃陶瓷的制备与表征

Journal of Biomimetics, Biomaterials and Tissue Engineering Pub Date : 2011-09-01 DOI: 10.4028/www.scientific.net/JBBTE.11.45

M. R. Majhi, R. Pyare, S. Singh

{"title":"Preparation and Characterization of CaF2 Doped Bioglass Ceramics","authors":"M. R. Majhi, R. Pyare, S. Singh","doi":"10.4028/www.scientific.net/JBBTE.11.45","DOIUrl":"https://doi.org/10.4028/www.scientific.net/JBBTE.11.45","url":null,"abstract":"Bioglass Ceramics having molar composition 40SiO2-(44-X)CaO-10MgO-6P2O5-XCaF2 (where X = 0 to 8%) were prepared by conventional melting process in an electric globar furnace at 1400±10°C. Controlled crystallizations were carried out to convert the bioglasses to their corresponding ceramics. Nucleation and crystallization regimes were carried out by differential thermal analysis. The crystalline phases termed hydroxy fluoroapatite, akermanite and wollastonite were identified by using x-ray diffraction analysis. The investigation of bioactivity for the prepared glass and glass ceramics was done by infrared absorption and infrared reflection spectra after immersion in simulated body fluid (SBF) for different periods at 37.8°C. Scanning electron microscope (SEM) analysis was carried out to investigate the surface texture. Micrographs show the formation of HCA layer on the surface of the bioglass ceramics samples after 7 days of SBF treatment. The surfaces of the samples were completely covered with irregular and needle-like aggregates of Ca–P layer. The released ions were estimated by atomic absorption spectroscopy. The chemical durability of these materials was determined by pH measurement methods and it was found that pH of the solution increases up from 1 to 7 days. Further, pH decreases with increasing time period, from 15 to 30 days in SBF solution.","PeriodicalId":15198,"journal":{"name":"Journal of Biomimetics, Biomaterials and Tissue Engineering","volume":"26 1","pages":"45 - 66"},"PeriodicalIF":0.0,"publicationDate":"2011-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75885706","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 3

Study on Culture of Human Dental Pulp Stem Cells to Apply in Tissue Engineering 人牙髓干细胞培养在组织工程中的应用研究

Journal of Biomimetics, Biomaterials and Tissue Engineering Pub Date : 2011-09-01 DOI: 10.4028/www.scientific.net/JBBTE.11.13

Tran Le Bao Ha, Doan Nguyen Vu, T. Quan, Ngoc Phan Kim, Hung Hoang Tu, Bao Tram Hoang Dao, Ngoc Mai Dang Vu, T. Nguyen

{"title":"Study on Culture of Human Dental Pulp Stem Cells to Apply in Tissue Engineering","authors":"Tran Le Bao Ha, Doan Nguyen Vu, T. Quan, Ngoc Phan Kim, Hung Hoang Tu, Bao Tram Hoang Dao, Ngoc Mai Dang Vu, T. Nguyen","doi":"10.4028/www.scientific.net/JBBTE.11.13","DOIUrl":"https://doi.org/10.4028/www.scientific.net/JBBTE.11.13","url":null,"abstract":"Dental pulp cell research might open a promising application in tooth tissue regeneration. The aim of this study is to establish a protocol for in vitro culture the human dental pulp stem cells to apply in tissue engineering. Human premolar and impacted third molars were collected and disinfected. Dental pulp fragments were cultured with Dulbecco's Modified Eagle Medium: Nutrient Mixture F-12 (DMEM/F12) medium supplemented with 10% Fetal Bovine Serum (FBS). Dental pulp stem cells (DPSCs) were identified using proliferation assay, RT-PCR and flow cytometry. Growth of DPSCs on dentin surface was assessed by MTT assay. The study showed that we successfully isolated, cultured and characterized dental pulp cells by outgrowth method. Cultured population of cells expressed in high level of Oct4, CD146, CD90, CD44. DPSCs proliferated on chemically and mechanically treated dentin surface. This research provides important information and a basis for further investigations to establish dental tissue engineering protocols.","PeriodicalId":15198,"journal":{"name":"Journal of Biomimetics, Biomaterials and Tissue Engineering","volume":"161 1","pages":"13 - 20"},"PeriodicalIF":0.0,"publicationDate":"2011-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83168514","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 7