Journal of Biomimetics, Biomaterials and Tissue Engineering最新文献_第10页

Bone Regeneration around Dental Implants as a Treatment for Peri-Implantitis: A Review of the Literature 牙种植体周围骨再生治疗种植体周围炎:文献综述

Journal of Biomimetics, Biomaterials and Tissue Engineering Pub Date : 2011-09-01 DOI: 10.4028/www.scientific.net/JBBTE.11.21

K. Subramani, R. Mathew, H. Hosseinkhani, M. Hosseinkhani

引用次数: 13

Preparation of Protein-Loaded Poly(L-Lactide) Microspheres by Solution-Enhanced Dispersion by Supercritical CO2 超临界CO2溶液增强分散法制备载蛋白聚l -丙交酯微球

Journal of Biomimetics, Biomaterials and Tissue Engineering Pub Date : 2011-09-01 DOI: 10.4028/www.scientific.net/JBBTE.11.93

A. Chen, C. Zhao, Shi-Bin Wang, Yuangang Liu

{"title":"Preparation of Protein-Loaded Poly(L-Lactide) Microspheres by Solution-Enhanced Dispersion by Supercritical CO2","authors":"A. Chen, C. Zhao, Shi-Bin Wang, Yuangang Liu","doi":"10.4028/www.scientific.net/JBBTE.11.93","DOIUrl":"https://doi.org/10.4028/www.scientific.net/JBBTE.11.93","url":null,"abstract":"SiO2-hemoglobin-poly(L-lactide) (SiO2-Hb-PLLA) microspheres were prepared in a process of solution-enhanced dispersion by supercritical CO2 (SEDS). SiO2 nanoparticles were loaded with Hb by adsorption firstly and then the Hb-SiO2 nanoparticles were further coated with PLLA by the SEDS process. The resulted microcapsules were characterized by scanning electron microscope (SEM), laser diffraction particle size analyser and Fourier transform infrared spectrometer (FTIR). The drug release profiles were also determined. The Hb-SiO2-PLLA microspheres have a narrow particle size distribution (PDI 0.189) with a mean particle size of 897nm and a drug loading of 7.1%. After coating with PLLA, the drug release from SiO2-Hb-PLLA showed a sustained process mainly in zero-order kinetics; only 3.7% drug was released in the first 24 hours, versus 51.9% for those without coating, which revealed that the coating of PLLA significantly retarded the drug release. The results also indicate that the SEDS process is a typical physical process to produce protein-loaded polymer microspheres without changing the molecular structure of proteins, which is potential in the application of designing proteins drug delivery system.","PeriodicalId":15198,"journal":{"name":"Journal of Biomimetics, Biomaterials and Tissue Engineering","volume":"257 1","pages":"100 - 93"},"PeriodicalIF":0.0,"publicationDate":"2011-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78853021","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Beta-2 Microglobulin Removal by Immunoextraction and Passive Adsorption in High-Flux Dialyzers 高通量透析器中β -2微球蛋白的免疫提取和被动吸附去除

Journal of Biomimetics, Biomaterials and Tissue Engineering Pub Date : 2011-09-01 DOI: 10.4028/www.scientific.net/JBBTE.11.35

M. Branham, T. Govender, E. Ross

{"title":"Beta-2 Microglobulin Removal by Immunoextraction and Passive Adsorption in High-Flux Dialyzers","authors":"M. Branham, T. Govender, E. Ross","doi":"10.4028/www.scientific.net/JBBTE.11.35","DOIUrl":"https://doi.org/10.4028/www.scientific.net/JBBTE.11.35","url":null,"abstract":"The objectives in this study were to compare the removal of 2-M via different dialyzers (high- and low flux) under equilibrium or sink conditions, wherein there was highly selective antibody-based facilitated transport into a small volume dialysate reservoir. Using an in vitro haemodialysis model we perfused high-flux polymethylmethacrylate (PMMA), high-flux cellulose diacetate (CDA), and a low-flux polysulfone (PSF) membranes with known amounts of 2-M through the intracapillary space. Anti-2-M antibodies added to the extracapillary space were shown to create sink conditions across the membrane when its pore size is sufficiently large for diffusion and if 2-M is not strongly adsorbed to the membrane surface. Our results indicate that 2-M (~12kDa) does not penetrate low-flux dialyzers and that its adsorption to intracapillary PSF surfaces does not substantially affect clearance. 2-M strongly adsorbed to high-flux PMMA dialyzers (ko = 0.0271+0.002 min-1), but without significant clearance enhancement due to circulating antibodies. A significant clearance enhancement (101.2%+24.89) for 2-M due to immunoextraction was observed in the high-flux cellulose acetate dialyzers, but without passive adsorption to the surface. These studies demonstrate the utility of in vitro haemodialysis experiments to elucidate midsize molecule clearance in dialysis membranes under controlled conditions. The use of anti-2-M antibodies as dialysate additives might be feasible in the removal of 2-M from whole blood, highlighting the advantages of selective antibody-based extraction of disease-causing toxins into potentially simple extracorporeal devices with small volume receiver compartments.","PeriodicalId":15198,"journal":{"name":"Journal of Biomimetics, Biomaterials and Tissue Engineering","volume":"57 1","pages":"35 - 44"},"PeriodicalIF":0.0,"publicationDate":"2011-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81543036","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A Theoretical Model to Fracture in Cell Membrane 细胞膜断裂的理论模型

Journal of Biomimetics, Biomaterials and Tissue Engineering Pub Date : 2011-09-01 DOI: 10.4028/www.scientific.net/JBBTE.11.67

M. Buonsanti, A. Pontari

引用次数: 0

Pearl – A Nano-Composite & Natural Super Dielectric 珍珠-一种纳米复合材料和天然超级电介质

Journal of Biomimetics, Biomaterials and Tissue Engineering Pub Date : 2011-09-01 DOI: 10.4028/www.scientific.net/JBBTE.11.1

S. S. Pradhan, A. Sarkar

引用次数: 2

Trapping and Manipulation of Bioparticles by a 3-D Optimal Multiple-Designed Offset Carbon-Microelectrode Array in C-MEMS Fabrication C-MEMS制造中三维优化多设计偏移碳微电极阵列捕获和操纵生物微粒

Journal of Biomimetics, Biomaterials and Tissue Engineering Pub Date : 2011-05-01 DOI: 10.4028/www.scientific.net/JBBTE.10.25

M. Malik, Tiejia Shi, Zirong Tang

{"title":"Trapping and Manipulation of Bioparticles by a 3-D Optimal Multiple-Designed Offset Carbon-Microelectrode Array in C-MEMS Fabrication","authors":"M. Malik, Tiejia Shi, Zirong Tang","doi":"10.4028/www.scientific.net/JBBTE.10.25","DOIUrl":"https://doi.org/10.4028/www.scientific.net/JBBTE.10.25","url":null,"abstract":"A dielectrophoretic approach with latest developed three-dimensional (3-D) carbon micro-electro-mechanical system (C-MEMS) has been extended as a potential route with idyllic solution to recommend a low-cost, biocompatible and high throughput manipulation and positioning for bio-particles as compared to 2D-planar microelectrodes. Presented in this paper is a novel platform for modelling and simulation of C-MEMS microfabrication process for dielectrophoresis (DEP) force based on various 3-D offset-microelectrode configurations. Numerical solutions are employed to investigate the upshots of multi-designed microelectrodes, applied voltage, electrode edge-to-edge gap and geometric size of microelectrodes on the electric field intensity gradient, induced by an AC voltage for the deployment of broad categories of bioparticles creation, utilization and their manipulation (separation, concentration, transportation and focusing). Sharp edge electrodes are the principle focus of this paper for DEP manipulation that is more convenient to enhance the electric field intensity distribution. The results show that square column electrodes configuration comparatively create large gradient magnitude in electric field intensity as compared to all other configurations. It is also observed that electric field extends drastically with increases in microelectrode height. These findings are consistent with literature experimental reports and will provide vital strategy for optimal design of DEP devices with 3-D C-MEMS.","PeriodicalId":15198,"journal":{"name":"Journal of Biomimetics, Biomaterials and Tissue Engineering","volume":"54 1","pages":"25 - 42"},"PeriodicalIF":0.0,"publicationDate":"2011-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79037226","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

In Vitro Structural Changes of Nano-Bacterial Cellulose Immersed in Phosphate Buffer Solution 纳米细菌纤维素在磷酸盐缓冲液中的体外结构变化

Journal of Biomimetics, Biomaterials and Tissue Engineering Pub Date : 2011-05-01 DOI: 10.4028/www.scientific.net/JBBTE.10.55

Y. Chen, T. Xi, Yufei Zheng, Liangyu Zhou, Y. Wan

引用次数: 20

Anti-Biofouling of a Novel Cross-Linked Copolymer Containing a HMBA Side Chain 一种新型含HMBA侧链交联共聚物的抗生物污染性能

Journal of Biomimetics, Biomaterials and Tissue Engineering Pub Date : 2011-05-01 DOI: 10.4028/www.scientific.net/JBBTE.10.1

Qiang Wang, Zhuang Yu, L. Yu

{"title":"Anti-Biofouling of a Novel Cross-Linked Copolymer Containing a HMBA Side Chain","authors":"Qiang Wang, Zhuang Yu, L. Yu","doi":"10.4028/www.scientific.net/JBBTE.10.1","DOIUrl":"https://doi.org/10.4028/www.scientific.net/JBBTE.10.1","url":null,"abstract":"Biofouling on underwater engineered structures, especially on ship hulls, results in increased operational and maintenance costs. Fouling is not only of an ecological interest, but it is also important from applied and commercial perspectives. With the development of society, widely used Tributyltin compounds (TBT) for biofouling control have been prohibited worldwide at the end of 2008. The need to develop new environment friendly antifouling agents has been highlighted. Herein we report on the synthesis and characterization of a novel cross-linkable copolymer containing a HMBA side chain. The paper is mainly focused on the synthesis of novel resin and its antifouling performance. Apart from use of acrylate monomer, the two other important monomers γ-methacryloxypropyltrimethoxysilane (HD-70) and N-(4-Hydroxy-3-Methoxy-Benzyl) acrylanine (HMBA) were selected to construct low surface energy materials. Finally, the antifouling properties of resins were carried through by the colonization of benthic diatoms (Nitzschia flosterium) and ocean plates of an offshore platform. Experimental results indicated the novel resins containing a HMBA side chain possessing better antifouling properties than a standard polydimethyl siloxane (PDMS) coating in the Qingdao ocean.","PeriodicalId":15198,"journal":{"name":"Journal of Biomimetics, Biomaterials and Tissue Engineering","volume":"46 1","pages":"1 - 5"},"PeriodicalIF":0.0,"publicationDate":"2011-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87736282","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Clinical Significance of Aspirin on Blood Flow through Stenotic Blood Vessels 阿司匹林对狭窄血管血流的临床意义

Journal of Biomimetics, Biomaterials and Tissue Engineering Pub Date : 2011-05-01 DOI: 10.4028/www.scientific.net/JBBTE.10.17

S. R. Shah

{"title":"Clinical Significance of Aspirin on Blood Flow through Stenotic Blood Vessels","authors":"S. R. Shah","doi":"10.4028/www.scientific.net/JBBTE.10.17","DOIUrl":"https://doi.org/10.4028/www.scientific.net/JBBTE.10.17","url":null,"abstract":"In this present study a two-phase model for the influence of aspirin on peripheral layer viscosity for physiological characteristics of blood flow through stenosed blood vessels using Casson’s fluid model has been obtained. Flow of blood with axially non-symmetric but radially symmetric stenosis geometry is considered. The non-linear pressure equations have been solved with help of boundary conditions and the results are displayed graphically for different flow characteristics. It was found that the resistance to flow decreases as stenosis shape parameter increases whereas the resistance to flow increases with increasing values of stenosis length, stenosis size and peripheral layer viscosity. The effects of stenosis severity and wall shear stress are discussed in the present computational analysis. Comparisons between the measured and computed peripheral layer viscosity profiles are favourable to the solutions. As a result it can be concluded that a regular dose of Asprin decreases the blood viscosity by diluting the blood of diabetic patients which ultimately decreases the blood pressure. For the validation of the numerical model, the computation results are compared with the experimental data and results from published literature.","PeriodicalId":15198,"journal":{"name":"Journal of Biomimetics, Biomaterials and Tissue Engineering","volume":"25 1","pages":"17 - 24"},"PeriodicalIF":0.0,"publicationDate":"2011-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88569953","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 5

Perfusion Bioreactor Development for Functional Cartilage Implant: A Technical Note 功能性软骨植入物灌注生物反应器的发展:技术说明

Journal of Biomimetics, Biomaterials and Tissue Engineering Pub Date : 2011-05-01 DOI: 10.4028/WWW.SCIENTIFIC.NET/JBBTE.10.75

C. Mahapatra, K. Pramanik

引用次数: 0