细胞膜断裂的理论模型

M. Buonsanti, A. Pontari
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引用次数: 0

摘要

本文提出了一种新的模拟生物组织破坏的应力函数。在假设细胞膜可以建模为新胡克材料的前提下,我们在非线性弹性的框架下发展了这个问题。我们试图模拟细胞冷冻保存中发生冻结和解冻时的冰核现象。冰种子产生的表面可以是柔软的,也可以是褶皱的,当褶皱出现时,就会对细胞膜产生冲击接触。将我们的注意力限制在合适的一维子集上,我们将多重临界点定理推广到我们的模型上。根据生物材料的应力场和应变场分布,找到了符合经典断裂模型的特解和响应函数。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
A Theoretical Model to Fracture in Cell Membrane
A new stress function modelling the fails in biological tissue is here proposed. Under the assumption that the cell membrane may be modelled as neo-Hookean materials, we develop the problem in the framework of non-linear elasticity. We attempt to model the ice nucleation phenomenon when freezing and thawing occurs in cellular cryo-preservation. The ice seed generated surface can be either soft or wrinkled and, when the latter emerges a punch contact against the cell membrane takes place. Restricting our attention on opportune mono-dimensional sub-set, we extend the multiple critical points theorem at our model. We find a particular solution in agreement to the classical fracture models besides a response function in accordance to the stress and strain field distribution in biological materials.
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