Journal of Biomimetics, Biomaterials and Tissue Engineering最新文献_第7页

Comparative Investigations of the Sandfish’s β-Keratin (Reptilia: Scincidae: Scincus scincus). Part 1: Surface and Molecular Examinations 沙鱼β-角蛋白的比较研究(爬行纲:沙鱼科:沙鱼科)。第1部分:表面和分子检查

Journal of Biomimetics, Biomaterials and Tissue Engineering Pub Date : 2012-10-01 DOI: 10.4028/www.scientific.net/JBBTE.15.1

Konrad Staudt, F. Saxe, H. Schmied, Raphael Soeur, W. Böhme, W. Baumgartner

{"title":"Comparative Investigations of the Sandfish’s β-Keratin (Reptilia: Scincidae: Scincus scincus). Part 1: Surface and Molecular Examinations","authors":"Konrad Staudt, F. Saxe, H. Schmied, Raphael Soeur, W. Böhme, W. Baumgartner","doi":"10.4028/www.scientific.net/JBBTE.15.1","DOIUrl":"https://doi.org/10.4028/www.scientific.net/JBBTE.15.1","url":null,"abstract":"The Sandfish (Scincidae: Scincus Scincus) Is a Lizard Capable of Moving through Desert Sand in a Swimming-Like Fashion. the Epidermis of this Lizard Shows a High Resistance against Abrasion Together with a Low Friction to Sand as an Adaption to a Subterranean Life below the Desert’s Surface, Outperforming even Steel. the Low Friction Is Mainly Caused by Chemical Composition of the Scales, which Consist of Glycosylated β-Keratins. in this Study, the Friction, the Micro-Structure, the Glycosylation of the β-Keratin Proteins and β-Keratin Coding DNA of the Sandfish in Comparison to other Reptilian Species Was Investigated, Mainly with the Closely Related Berber Skink (Scincidae: Eumeces Schneideri) and another Sand Swimming Species, the Not Closer Related Shovel-Snouted Lizard (Lacertidae: Meroles Anchietae). Glycosylated β-Keratins of the Sandfish, Visualized with Different Lectins Resulted in O-Linked Glycans through PNA Employed as Carbohydrate Marker. Furthermore, the Glycosylation of β-Keratins in Various Squamatean Species Was Investigated and All Species Tested Were Found Positive; however, it Seems Like both Sand Swimming Species Examined Have a much Stronger Glycosylation of their β-Keratins. in Order to Prove this Finding through a Genetic Foundation, DNA of a β-Keratin Coding Gene of the Sandfish Was Sequenced and Compared with a Homologue Gene of Eumeces Schneideri. by Comparison of the Protein Sequence, a Higher Abundance of O-Glycosylation Sites Was Found in the Sandfish (enabled through the Amino Acids Serine and Threonine), Giving Molecular Support for a Higher Glycosylation of the β-Keratins in this Species.","PeriodicalId":15198,"journal":{"name":"Journal of Biomimetics, Biomaterials and Tissue Engineering","volume":"34 1","pages":"1 - 16"},"PeriodicalIF":0.0,"publicationDate":"2012-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82674435","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 10

Preparation of Poly(vinyl alcohol)/Chitosan-Blended Hydrogels: Properties, In Vitro Studies and Kinetic Evaluation 聚乙烯醇/壳聚糖共混水凝胶的制备:性能、体外研究及动力学评价

Journal of Biomimetics, Biomaterials and Tissue Engineering Pub Date : 2012-10-01 DOI: 10.4028/www.scientific.net/JBBTE.15.63

M. Hosseini, I. Amjadi, N. Haghighipour

{"title":"Preparation of Poly(vinyl alcohol)/Chitosan-Blended Hydrogels: Properties, In Vitro Studies and Kinetic Evaluation","authors":"M. Hosseini, I. Amjadi, N. Haghighipour","doi":"10.4028/www.scientific.net/JBBTE.15.63","DOIUrl":"https://doi.org/10.4028/www.scientific.net/JBBTE.15.63","url":null,"abstract":"Articular Cartilage Defects Are a Recent Critical Orthopaedic Issue. Hydrogels Have Been Widely Used in Soft Tissue Engineering Scaffolds as their Structures Are Similar to the Macromolecular-Based Components in the Human Body. Hydrogels Including those Based on Poly(vinyl Alcohol) (PVA) and Chitosan Are of Considerable Interest for Utilization in the Field of Tissue Engineering because of their Appropriate Biocompatibility. PVA Gels Can Be Formed by Chemical or Physical Crosslinking. the “freezing-Thawing” (FT) Process Is the Most Mild, Facile and Effective Method to Produce Physically Crosslinked PVA Gel, because it Does Not Require the Presence of the Crosslinking Agent that May Cause Toxicity. in this Study Hydrogels Based on PVA and Chitosan in Different Blend Ratios Were Prepared, and the Effect of the Freeze-Thaw Cycles and Glutaraldehyde on the Hydrogel Properties Was Investigated. the Results Showed that Freeze-Thaw Cycles Increased the Tensile Strength and the Samples’ Resistance to Degradation. the Biocompatibility of the Hydrogels Was Analysed Using Chondrocyte Cells Separated from Distal Femur of Men. Cell Toxicity Assay Performed for Measurement of Cell Viability of the Samples Indicated Biocompatibility.","PeriodicalId":15198,"journal":{"name":"Journal of Biomimetics, Biomaterials and Tissue Engineering","volume":"40 1","pages":"63 - 72"},"PeriodicalIF":0.0,"publicationDate":"2012-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77405245","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 7

Microwave Sintering of ZrO2 Fiber-Reinforced Hydroxyapatite Matrix Composites ZrO2纤维增强羟基磷灰石基复合材料的微波烧结

Journal of Biomimetics, Biomaterials and Tissue Engineering Pub Date : 2012-07-26 DOI: 10.4028/www.scientific.net/JBBTE.14.93

N. Ehsani, A. Ruys, C. Sorrell

引用次数: 2

Analysis on Rigidity of Mitral Valve Leaflet (MVL) and Backflow Problems during Cardiac Cycle 心脏周期中二尖瓣小叶刚度及回流问题分析

Journal of Biomimetics, Biomaterials and Tissue Engineering Pub Date : 2012-07-02 DOI: 10.4028/www.scientific.net/JBBTE.13.75

Mohd Azrul Hisham Mohd Adib, Nur Hazreen Mohd Hasni, K. Osman, O. Maskon

引用次数: 5

Effect of Heat Treatment Temperature on Microstructure of Sol-Gel Derived Wollastonite Coating 热处理温度对溶胶-凝胶型硅灰石涂层微观结构的影响

Journal of Biomimetics, Biomaterials and Tissue Engineering Pub Date : 2012-07-01 DOI: 10.4028/www.scientific.net/JBBTE.14.75

Q. Bao, Jia Liu

引用次数: 0

Biovitroceramic Coatings on Modified Surface of 316L Austenitic Stainless Steel 316L奥氏体不锈钢改性表面的生物陶瓷涂层

Journal of Biomimetics, Biomaterials and Tissue Engineering Pub Date : 2012-07-01 DOI: 10.4028/www.scientific.net/JBBTE.13.19

Iulia Mirela Britchi, M. Olteanu, N. Ene, N. Stanica

{"title":"Biovitroceramic Coatings on Modified Surface of 316L Austenitic Stainless Steel","authors":"Iulia Mirela Britchi, M. Olteanu, N. Ene, N. Stanica","doi":"10.4028/www.scientific.net/JBBTE.13.19","DOIUrl":"https://doi.org/10.4028/www.scientific.net/JBBTE.13.19","url":null,"abstract":"Austenitic stainless steel 316L is widely used in implantology due to its biocompatibility, a lower price than titanium and because can be easily mechanically machined. The drawback is due to the fact that toxic nickel and chromium ions are released into human body fluids. Our proposal is to coat 316L austenitic stainless steel with biovitroceramic layers made of oxide system SiO2, B2O3, Na2O, CaO, TiO2, P2O5, K2O, Li2O and MgO by means of an enamelling procedure in order to hinder the release of Ni and Cr ions from the metallic implant surface toward the tissue around the implant. In order to achieve a firm adherence of biovitroceramic layer onto the metal, with an optimal composition for biocompatibility and bioactivity, we have modified the steel surface by a titanizing thermochemical treatment. The adherence of the biovitroceramic layer to the 316L stainless steel with modified surface is very good. The biovitroceramic coating - metallic substrate couple was studied by optical microscopy, electron microscopy (SEM and EDAX), X-ray diffraction analysis and microhardness trials.","PeriodicalId":15198,"journal":{"name":"Journal of Biomimetics, Biomaterials and Tissue Engineering","volume":"9 1","pages":"19 - 30"},"PeriodicalIF":0.0,"publicationDate":"2012-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82072793","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Fractal Analysis and Biophysical Investigation of Muscular Tissue Damaged due to Low Temperature: A Pilot Study 低温损伤肌肉组织的分形分析与生物物理研究

Journal of Biomimetics, Biomaterials and Tissue Engineering Pub Date : 2012-07-01 DOI: 10.4028/www.scientific.net/JBBTE.14.43

G. Bianciardi, M. Buonsanti, A. Pontari, S. Tripodi

{"title":"Fractal Analysis and Biophysical Investigation of Muscular Tissue Damaged due to Low Temperature: A Pilot Study","authors":"G. Bianciardi, M. Buonsanti, A. Pontari, S. Tripodi","doi":"10.4028/www.scientific.net/JBBTE.14.43","DOIUrl":"https://doi.org/10.4028/www.scientific.net/JBBTE.14.43","url":null,"abstract":"Severe damage is produced in tissues by freezing and thawing. Until now, a great majority of the studies are performed qualitatively, lacking any quantitative approach. An important step is to choose the best option among different freezing methods. To approach the complex problem of damage produced in tissues by freezing, in this paper we present the classical mechanics approach and a quantitative study making use of a fractal methodology (evaluation of fractal dimension by box-counting method). A comparative fractal analysis between two different steps of freezing the human thoracic diaphragm muscle has been performed to quantify the voids and cracks produced by freezing (samples were placed in a cryostat chamber). Moreover, a standard Euclidean morphometry was performed to determine area and shape of the muscle nuclei after the two steps of freezing. Fractal dimension of the ice-tissue interface structures increased with decreasing temperature (p<0.0001), percentage of cell muscle decreased (p<0.01), while standard morphometry of the nuclei didnt show any modifications. Our results show the ability of the fractal approach to accurately quantify the damage produced by freezing and reveals that the lowest temperature produces the most damage.","PeriodicalId":15198,"journal":{"name":"Journal of Biomimetics, Biomaterials and Tissue Engineering","volume":"117 1","pages":"43 - 51"},"PeriodicalIF":0.0,"publicationDate":"2012-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91516124","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

A Novel Dynamic 3-Dimensional Construct for Respiratory Tissue Engineering 一种用于呼吸组织工程的新型动态三维结构

Journal of Biomimetics, Biomaterials and Tissue Engineering Pub Date : 2012-07-01 DOI: 10.4028/www.scientific.net/JBBTE.14.31

C. Poon, Mei Zhang, A. Ruys, A. Hong, Christelle Catuogno, P. Boughton

{"title":"A Novel Dynamic 3-Dimensional Construct for Respiratory Tissue Engineering","authors":"C. Poon, Mei Zhang, A. Ruys, A. Hong, Christelle Catuogno, P. Boughton","doi":"10.4028/www.scientific.net/JBBTE.14.31","DOIUrl":"https://doi.org/10.4028/www.scientific.net/JBBTE.14.31","url":null,"abstract":"Tissue engineering of airway tissues poses many complex challenges. As tissue form is determined by function and vice versa, it is necessary to consider mechanical and physiological constraints in conjunction with standard biologic and biochemical factors when culturing tissues in vitro. This study involved the development and validation of a novel 3-dimensional (3-D) construct with the capacity to periodically expose a cell scaffold to air and medium at application of physiologic strain rates. The ultimate objective was to mimic respiratory conditions experienced by airway tissues during breathing whilst ensuring compatibility with proven cell culture techniques. The Biaxx design consists of an elastomeric porous synthetic scaffold integrated with a unique biopolymer coupling unit which engages with an IAXSYS bioreactor actuator. Uniform biaxial strain was imparted by the coupling unit whilst simultaneously creating a periodic air-liquid interface. Biaxx scaffolds with and without a coating of particulate 45S5 bioglass were employed in an assay to assess cell attachment and proliferation whilst subject to periodic strain. Physiologic lung tissue strain of 5-15% was achieved for over 200,000 cycles at 0.2Hz. Preliminary biological studies with H460 human lung carcinoma cells confirmed cell attachment, growth and proliferation on this promising construct.","PeriodicalId":15198,"journal":{"name":"Journal of Biomimetics, Biomaterials and Tissue Engineering","volume":"128 1","pages":"31 - 42"},"PeriodicalIF":0.0,"publicationDate":"2012-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88719839","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

Finite Element Modelling of Rheological Property of Curing PMMA Bone Cement - Part 2 Effect of Bone Cement Amount 固化PMMA骨水泥流变特性的有限元模拟-第2部分骨水泥量的影响

Journal of Biomimetics, Biomaterials and Tissue Engineering Pub Date : 2012-07-01 DOI: 10.4028/www.scientific.net/JBBTE.13.69

M.M. Rahman, A. Olabi, M. Hashmi

引用次数: 0

Achievement of Pentoxifylline for Blood Flow through Stenosed Artery 己酮可可碱在狭窄动脉血流中的应用

Journal of Biomimetics, Biomaterials and Tissue Engineering Pub Date : 2012-07-01 DOI: 10.4028/www.scientific.net/JBBTE.13.81

S. R. Shah, S. U. Siddiqui

{"title":"Achievement of Pentoxifylline for Blood Flow through Stenosed Artery","authors":"S. R. Shah, S. U. Siddiqui","doi":"10.4028/www.scientific.net/JBBTE.13.81","DOIUrl":"https://doi.org/10.4028/www.scientific.net/JBBTE.13.81","url":null,"abstract":"Blood-viscosity reducing drugs like “Pentoxifylline” improve blood flow by making the blood less viscous. The resistance to flow of blood in diabetic patients is higher than in non-diabetic patients. Thus diabetic patients with higher resistance to flow are more prone to high blood pressure. Therefore the resistance to blood flow in case of diabetic patients may be reduced by reducing viscosity of the plasma. Viscosity of plasma can be reducing by giving Pentoxifylline. In this paper an attempt has been made to investigate the blood flow behaviour and significance of non-Newtonian viscosity through a stenosed artery using Bingham Plastic fluid model. Numerical illustrations presented at the end of the paper provide the results for the resistance to flow, apparent viscosity and the wall shear stress through their graphical representations. It has been shown that the resistance to flow, apparent viscosity and wall shear stress increases with the size of the stenosis but these increases are comparatively small due to non-Newtonian behaviour of the blood indicating the usefulness of its rheological character in the functioning of the diseased arterial circulation.","PeriodicalId":15198,"journal":{"name":"Journal of Biomimetics, Biomaterials and Tissue Engineering","volume":"59 1","pages":"81 - 89"},"PeriodicalIF":0.0,"publicationDate":"2012-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84245213","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0