心脏周期中二尖瓣小叶刚度及回流问题分析

Mohd Azrul Hisham Mohd Adib, Nur Hazreen Mohd Hasni, K. Osman, O. Maskon
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引用次数: 5

摘要

二尖瓣出现的问题现在每天都让越来越多的患者感到担忧。在二尖瓣中,结构和材料特性的区域差异共同影响整个瓣膜的生物力学。先前的研究表明,二尖瓣小叶组织是高度可扩展的。本研究的目的是探讨二尖瓣小叶刚性与回流问题之间的关系。研究了二尖瓣的收缩和舒张状态,以及有无心室的情况。在ADINA-FSI中建立二尖瓣小叶(MVL)的二维模型进行计算流体动力学分析。结果表明,二尖瓣叶的刚度与回流体积呈线性关系。总之,这些计算技术在二尖瓣小叶疾病和假体失效的研究中是非常有用的。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Analysis on Rigidity of Mitral Valve Leaflet (MVL) and Backflow Problems during Cardiac Cycle
Problems that occur in the mitral valve are now worrying an increasing number of patients each day. In the mitral valve, regional variations in structure and material properties combine to affect the biomechanics of the entire valve. Previous studies have shown that the mitral valve leaflet tissue is highly extensible. The objective of this study was to investigate the relationship between the rigidity of mitral valves leaflet and backflow problems. Two stages of mitral valves analysis systolic and diastolic condition and also with and without ventricle were investigated. 2D models of the mitral valve leaflet (MVL) were created in ADINA-FSI for computational fluid dynamic analysis. The results show a linear relationship between rigidity of the mitral valves leaflet and volume of backflow. In conclusion, these computational techniques are very useful in the study of both mitral valve leaflet disease and failure of prostheses.
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