Journal of Biomimetics, Biomaterials and Tissue Engineering最新文献_第6页

Self-Healing Materials as New Biologically Inspired Materials 自我修复材料作为新的生物启发材料

Journal of Biomimetics, Biomaterials and Tissue Engineering Pub Date : 2012-12-01 DOI: 10.4028/www.scientific.net/JBBTE.16.11

F. Ghezzo, X. Miao

{"title":"Self-Healing Materials as New Biologically Inspired Materials","authors":"F. Ghezzo, X. Miao","doi":"10.4028/www.scientific.net/JBBTE.16.11","DOIUrl":"https://doi.org/10.4028/www.scientific.net/JBBTE.16.11","url":null,"abstract":"Lightweight, high strength fibre-reinforced polymeric composites are leading materials in many advanced applications including biomedical components. These materials offer the feasibility to incorporate multi functionalities due to their internal architecture, heterogeneity of materials and the flexibility of combining them using currently available fabrication methods. In spite of the excellent properties of these materials, their failure is still a questionable and not well predicted event. Delamination, debonding and micro-cracks are only some of the failure mechanisms that affect the matrices of polymer based composites. More complex cases exist with the combination of multiple failure mechanisms. In such cases a self-repairing mechanism that can be auto-triggered in the matrix material once the crack has been formed, would be very beneficial for all the applications of these materials, reducing maintenance costs and increasing their safety and reliability. Self-healing materials have been studied for more than a decade by now, with the specific objective of reducing the risks and costs of cracking and damage in a wide range of materials. Different approaches have been taken to create such materials, depending on the kind of material that needs to be repaired. The most popular methods developed for polymers and polymer reinforced composites are considered in this review. These methods include materials with micro-capsules containing a healing agent, and composites with matrices that can self-heal the cracks by repairing the broken molecular links upon external heating. While the first approach to healing has been widely used and studied in the past decade, in this review we focus on the second approach since less is reported in the literature and more difficult is the development of the materials based on such a method.","PeriodicalId":15198,"journal":{"name":"Journal of Biomimetics, Biomaterials and Tissue Engineering","volume":"21 1","pages":"11 - 25"},"PeriodicalIF":0.0,"publicationDate":"2012-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88726417","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Bacterial Biofilm Development on Polyethylene with Organic and Inorganic Reagents In Vitro 有机和无机试剂在聚乙烯上细菌生物膜的体外发育

Journal of Biomimetics, Biomaterials and Tissue Engineering Pub Date : 2012-12-01 DOI: 10.4028/www.scientific.net/JBBTE.16.97

Hong Li, Huan Li, Wei Zhao, Wei Zhang, Jun Ji

{"title":"Bacterial Biofilm Development on Polyethylene with Organic and Inorganic Reagents In Vitro","authors":"Hong Li, Huan Li, Wei Zhao, Wei Zhang, Jun Ji","doi":"10.4028/www.scientific.net/JBBTE.16.97","DOIUrl":"https://doi.org/10.4028/www.scientific.net/JBBTE.16.97","url":null,"abstract":"The antimicrobial efficacy of polyethylene (PE) with organic antibacterial agent and inorganic antibacterial agent were evaluated in this work. Moreover, inhibition to bacterial biofilm on their surfaces was investigated in detail. Our experimental results showed that both modified PE samples exhibited excellent antimicrobial performances against S. aureus and E. coli with low cell suspension. When cell suspension increased up to109 cell/ml, a large amount of bacteria (S. aureus and E. coli) and extracellular polysaccharide matrix adhered to the untreated PE and PE with inorganic antibacterial agent. On the other hand, adhesion, colonization and biofilm of S. aureus did not occur on PE with organic antibacterial agent, and a little E. coli survived on its surface. It was demonstrated that organic antibacterial agent had better ability to inhibit bacteria propagation than the inorganic one in initial time, and thus it prevented adherent bacteria to develop biofilm on the surface. The difference was derived from different initial effect time of them against bacteria. Therefore, it was a better approach to prevent catheter-related infections through addition of organic reagent into bulk material.","PeriodicalId":15198,"journal":{"name":"Journal of Biomimetics, Biomaterials and Tissue Engineering","volume":"40 1","pages":"107 - 97"},"PeriodicalIF":0.0,"publicationDate":"2012-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84847922","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Characterization and Degradation Behaviour of Anodized Magnesium-Hydroxyapatite Metal Matrix Composites 阳极氧化镁-羟基磷灰石金属基复合材料的表征与降解行为

Journal of Biomimetics, Biomaterials and Tissue Engineering Pub Date : 2012-12-01 DOI: 10.4028/www.scientific.net/JBBTE.16.55

P. Gill, N. Munroe, A. McGoron

引用次数: 4

A Novel Patient-Specific Regenerative Meniscal Replacement System 一种新型患者特异性再生半月板置换系统

Journal of Biomimetics, Biomaterials and Tissue Engineering Pub Date : 2012-12-01 DOI: 10.4028/www.scientific.net/JBBTE.16.83

A. H. Chan, Noel Young, G. Tran, B. Miles, A. Ruys, P. Boughton

{"title":"A Novel Patient-Specific Regenerative Meniscal Replacement System","authors":"A. H. Chan, Noel Young, G. Tran, B. Miles, A. Ruys, P. Boughton","doi":"10.4028/www.scientific.net/JBBTE.16.83","DOIUrl":"https://doi.org/10.4028/www.scientific.net/JBBTE.16.83","url":null,"abstract":"Knee meniscal injuries account for the greatest number of surgical procedures performed by orthopaedic surgeons worldwide. Each year in excess of 400,000 operations are performed in Europe and over one million in the United States and yet no suitable replacement for the meniscus is available. Fibrocartilage tissue engineering holds great potential in the regeneration of meniscal tissue however current developments have been limited. Difficulties in imitating the anisotropic nature of the meniscus, patient specific geometry, attaining sterility assurance requirements remain as developmental challenges for meniscal scaffold devices. A novel approach was developed to rapidly form terminally sterilized pre-packaged scaffold templates into anatomically matched regenerative meniscal implants. Formed meniscal implants exhibited the structural and functional architecture of the native meniscus. Meniscal implants fabricated using this method displayed mechanical properties approaching to that of the native meniscus and imparted rotational stability. Fixation techniques influenced the biomechanical response of implants and 45S5 bioactive glass modification was found to enhance radio-opacity of the scaffold. Biocompatibility of the implant was confirmed using a fibroblast cell culture model.","PeriodicalId":15198,"journal":{"name":"Journal of Biomimetics, Biomaterials and Tissue Engineering","volume":"1 1","pages":"83 - 95"},"PeriodicalIF":0.0,"publicationDate":"2012-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85347301","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Development of a Novel Biomimetic Dental Wear System 一种新型仿生牙戴系统的研制

Journal of Biomimetics, Biomaterials and Tissue Engineering Pub Date : 2012-10-01 DOI: 10.4028/www.scientific.net/JBBTE.15.23

Kazi Rizwana Mehzabeen, A. Sureshkumar, Arun Thangavel, Bevan J. Chong, M. Guazzato, A. Ruys, P. Boughton

引用次数: 3

Development of 3D Antibiotic-Eluting Bioresorbable Scaffold with Attenuating Envelopes 具有衰减包膜的三维抗生素洗脱生物可吸收支架的研制

Journal of Biomimetics, Biomaterials and Tissue Engineering Pub Date : 2012-10-01 DOI: 10.4028/www.scientific.net/JBBTE.15.55

B. Chow, A. Baume, P. Lok, Jake D. Cao, N. Coleman, A. Ruys, P. Boughton

{"title":"Development of 3D Antibiotic-Eluting Bioresorbable Scaffold with Attenuating Envelopes","authors":"B. Chow, A. Baume, P. Lok, Jake D. Cao, N. Coleman, A. Ruys, P. Boughton","doi":"10.4028/www.scientific.net/JBBTE.15.55","DOIUrl":"https://doi.org/10.4028/www.scientific.net/JBBTE.15.55","url":null,"abstract":"Thick Section 3D Bioresorbable Scaffolds Are Proposed as a Potential Alternative to Biologic Skin Grafts and Supportive Fillers for Non-Healing Chronic Wound Ulcers. Synthetic Bioresorbable Scaffolds Avoid Human and Animal Derived Contamination Risks, Provide Feasible Shelf Life, Availability and Cost, and Act as a Consistent Platform for Localized Drug Elution. A Bioresorbable Polyester-Based Scaffold (Infilon™) Was Investigated as a Drug Delivery Vehicle for Chloramphenicol Antibiotic (CAP) Combined with a Bioactive Envelope. the Effect of Varying Envelope Protocols on Antibiotic Elution Profile and Antimicrobial Potency on Scaffolds Were Analysed. the Maximum Antibiotic Loading Efficiency of the Scaffold Was 10.18% W/w. the Antibiotic Elution Profile Showed that the Burst Phase Lasted One Hour Subsequent to a Sustained Phase Approaching near Asymptotic Release. Envelope Permutations of Bulk Metallic Glass (BMG) and Bioglass 45S5 Reduced the Total Amount of Antibiotic Released by 1 to 1.8 Mg while the Polyethylene Oxide Envelope Extended the Burst Phase to 2 Hours. CAP Loaded Scaffolds Demonstrated Antimicrobial Effectiveness for 24 Hours. Results Show Potential for the Infilon™ Scaffold to Be Used as a Platform for Localized Antibiotic Delivery. Delivery Profiles Can Be Enhanced with Additional BMG or Bioglass Envelopes. this Approach Has Opportunity to Provide a Synergistic Coupling of Antimicrobial Action and the Harbouring of Granular Tissue Subsequent to Final Wound Healing.","PeriodicalId":15198,"journal":{"name":"Journal of Biomimetics, Biomaterials and Tissue Engineering","volume":"141 1","pages":"55 - 62"},"PeriodicalIF":0.0,"publicationDate":"2012-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75580496","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

Modelling and Tissue Engineering of Three Layers of Calvarial Bone as a Biomimetic Scaffold 三层颅骨骨仿生支架的建模与组织工程研究

Journal of Biomimetics, Biomaterials and Tissue Engineering Pub Date : 2012-10-01 DOI: 10.4028/www.scientific.net/JBBTE.15.37

F. Hosseinnejad, A. I. Imani Fooladi, F. Hafezi, S. M. Mafi, Afsaneh Amiri, M. Nourani

{"title":"Modelling and Tissue Engineering of Three Layers of Calvarial Bone as a Biomimetic Scaffold","authors":"F. Hosseinnejad, A. I. Imani Fooladi, F. Hafezi, S. M. Mafi, Afsaneh Amiri, M. Nourani","doi":"10.4028/www.scientific.net/JBBTE.15.37","DOIUrl":"https://doi.org/10.4028/www.scientific.net/JBBTE.15.37","url":null,"abstract":"In this Study, a New Zealand Rabbit Parietal Bone Was Cross-Sectioned, and Parameters such as Entire Thickness and the Thicknesses of the Compact and Spongy Tables Were Morphometrically Measured by Imagej Software. the Pore Size of the Cancellous Table Was Also Analysed, and a Calvarial Bone Model Was Created. Based upon a Natural Model for Bone Repair, a Nano-Structured Scaffold Was Designed Using Bioglass and Gelatin (BG) as its Main Components. the Scaffold Was Prepared Using Layer Solvent Casting Combined with Freeze-Drying, Layering Techniques, and other Commonly Used Techniques. the Fabricated BG Scaffolds Were Made with Different Percentages of Nanoparticles, and the 10% and 30% Constructions Were Found to Be Respectively Similar to Compact and Spongy Bone. we Fabricated Three Lamellar Scaffolds with Two Compact Layers on the outside and One Spongy Layer in the Middle to Mimic the Composition and Structure of Natural Bone. the Chemical, Physical, and Biological Tests (including Cell Seeding on Scaffold and MTT Assay) that Evaluated this Scaffold Examined its Capacity to Promote Bone Repair. Fabricated Scaffolds Implanted in Rabbit Calvaria and Evaluated the Bone Repair by X-Ray. this Mimetic BG Scaffold Could Be an Excellent Candidate for a Synthetic Calvarial Bone Graft.","PeriodicalId":15198,"journal":{"name":"Journal of Biomimetics, Biomaterials and Tissue Engineering","volume":"11 1","pages":"37 - 53"},"PeriodicalIF":0.0,"publicationDate":"2012-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74563333","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 5

Hydroxyapatite Matrix Composites by Hot Isostatic Pressing: Part 1. Alumina Fibre Reinforced 热等静压羟基磷灰石基复合材料:第1部分。氧化铝纤维增强

Journal of Biomimetics, Biomaterials and Tissue Engineering Pub Date : 2012-10-01 DOI: 10.4028/www.scientific.net/JBBTE.15.73

N. Ehsani, A. Ruys, C. Sorrell

引用次数: 5

Hydroxyapatite Matrix Composites by Hot Isostatic Pressing: Part 2. Zirconia Fibre and Powder Reinforced 热等静压羟基磷灰石基复合材料:第2部分。氧化锆纤维和粉末增强

Journal of Biomimetics, Biomaterials and Tissue Engineering Pub Date : 2012-10-01 DOI: 10.4028/www.scientific.net/JBBTE.15.85

N. Ehsani, C. Sorrell, A. Ruys

引用次数: 3

Kinematics Analysis of Foot Metatarsals Skeletal Rays through Inverse Modelling 基于逆建模的足跖骨射线运动学分析

Journal of Biomimetics, Biomaterials and Tissue Engineering Pub Date : 2012-10-01 DOI: 10.4028/www.scientific.net/JBBTE.15.17

Q. Hao, W. Shen, J. B. Ma, J. Li, X. Ren, Y. Gu

引用次数: 1