Journal of Biomimetics, Biomaterials and Tissue Engineering最新文献_第5页

Prediction on Behaviour of Blood Velocity and Mitral Leaflet Displacement in the Different Shapes of Heart Valve during Cardiac Cycle 心脏周期中不同形状心脏瓣膜血流速度和二尖瓣位移的预测

Journal of Biomimetics, Biomaterials and Tissue Engineering Pub Date : 2013-06-01 DOI: 10.4028/www.scientific.net/JBBTE.17.79

Mohd Azrul Hisham Mohd Adib, Faradila Naim, N. Hasni, K. Osman

{"title":"Prediction on Behaviour of Blood Velocity and Mitral Leaflet Displacement in the Different Shapes of Heart Valve during Cardiac Cycle","authors":"Mohd Azrul Hisham Mohd Adib, Faradila Naim, N. Hasni, K. Osman","doi":"10.4028/www.scientific.net/JBBTE.17.79","DOIUrl":"https://doi.org/10.4028/www.scientific.net/JBBTE.17.79","url":null,"abstract":"The number of cases for heart diseases is increasing every day, even though medication technologies are always improving and moving forward. In this paper, the objectives of the study are to investigate the effect of blood flow velocity and leaflet displacement using different shapes of simplified two dimensional heart valve leaflets in the diastole condition. Four different shapes of heart valve were created and the simulation was performed by using Fluid Structure Interaction (FSI). From the results obtained, the triangle shaped leaflet showed it had the highest blood velocity changes and leaflets displacement changes in a one second period when compared to the other three shapes. The outcome simulation result shows that a large vortex formed behind the leaflet and leaflet deformed when the blood flow into left ventricle is agreed with the results in literature. In conclusion, four different shapes of two dimensional model of mitral valve has been developed and investigated for applying the most suitable shape in future artificial valve design.","PeriodicalId":15198,"journal":{"name":"Journal of Biomimetics, Biomaterials and Tissue Engineering","volume":"39 1","pages":"79 - 85"},"PeriodicalIF":0.0,"publicationDate":"2013-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85501151","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 7

In Vitro Characterization of Calcium Salts as Delivery Vehicles for Insulin 钙盐作为胰岛素递送载体的体外表征

Journal of Biomimetics, Biomaterials and Tissue Engineering Pub Date : 2013-06-01 DOI: 10.4028/www.scientific.net/JBBTE.17.53

Loay Al-zube, Thakir D. Al-Momani, O. Al-Bataineh, L. Tahtamouni

引用次数: 0

Synthesis and Characterization of Molecularly Imprinted Polymers for Quercetin 槲皮素分子印迹聚合物的合成与表征

Journal of Biomimetics, Biomaterials and Tissue Engineering Pub Date : 2013-06-01 DOI: 10.4028/www.scientific.net/JBBTE.17.71

N. Verma, N. Trehan

引用次数: 1

Hot Isostatic Pressing (HIPing) of FeCralloy®-Reinforced Hydroxyapatite 铁合金®增强羟基磷灰石的热等静压(HIPing)

Journal of Biomimetics, Biomaterials and Tissue Engineering Pub Date : 2013-06-01 DOI: 10.4028/www.scientific.net/JBBTE.17.87

N. Ehsani, A. Ruys, C. Sorrell

引用次数: 7

Biocompatibility Assessment of Novel Bioresorbable Alloys Mg-Zn-Se and Mg-Zn-Cu for Endovascular Applications: In- Vitro Studies. 新型生物可吸收合金Mg-Zn-Se和Mg-Zn-Cu在血管内应用的生物相容性评估:体外研究。

Journal of Biomimetics, Biomaterials and Tissue Engineering Pub Date : 2013-01-01 DOI: 10.4028/www.scientific.net/JBBTE.17.25

Dharam Persaud-Sharma, Noah Budiansky, Anthony J McGoron

{"title":"Biocompatibility Assessment of Novel Bioresorbable Alloys Mg-Zn-Se and Mg-Zn-Cu for Endovascular Applications: In- Vitro Studies.","authors":"Dharam Persaud-Sharma, Noah Budiansky, Anthony J McGoron","doi":"10.4028/www.scientific.net/JBBTE.17.25","DOIUrl":"https://doi.org/10.4028/www.scientific.net/JBBTE.17.25","url":null,"abstract":"Previous studies have shown that using biodegradable magnesium alloys such as Mg-Zn and Mg-Zn-Al possess the appropriate mechanical properties and biocompatibility to serve in a multitude of biological applications ranging from endovascular to orthopedic and fixation devices. The objective of this study was to evaluate the biocompatibility of novel as-cast magnesium alloys Mg-1Zn-1Cu wt.% and Mg-1Zn-1Se wt.% as potential implantable biomedical materials, and compare their biologically effective properties to a binary Mg-Zn alloy. The cytotoxicity of these experimental alloys was evaluated using a tetrazolium based- MTS (3-(4,5-dimethylthiazol-2-yl)-5-(3-carboxymethoxyphenyl)-2-(4-sulfophenyl)-2H-tetrazolium) assay and a lactate dehydrogenase membrane integrity assay (LDH). The MTS assay was performed on extract solutions obtained from a 30-day period of alloy immersion and agitation in simulated body fluid to evaluate the major degradation products eluted from the alloy materials. Human foreskin fibroblast cell growth on the experimental magnesium alloys was evaluated for a 72 hour period, and cell death was quantified by measuring lactate dehydrogenase concentrations. Both Mg-Zn-Se and Mg-Zn-Cu alloys exhibit low cytotoxicity levels which are suitable for biomaterial applications. The Mg-Zn-Cu alloy was found to completely degrade within 72 hours, resulting in lower human foreskin fibroblast cell viability. The Mg-Zn-Se alloy was shown to be less cytotoxic than both the Mg-Zn-Cu and Mg-Zn alloys.","PeriodicalId":15198,"journal":{"name":"Journal of Biomimetics, Biomaterials and Tissue Engineering","volume":"17 ","pages":"25-44"},"PeriodicalIF":0.0,"publicationDate":"2013-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.4028/www.scientific.net/JBBTE.17.25","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"31752842","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 7

A review on bioactive porous metallic biomaterials 生物活性多孔金属生物材料的研究进展

Journal of Biomimetics, Biomaterials and Tissue Engineering Pub Date : 2013-01-01 DOI: 10.4172/1662-100X.1000104

K. Mediaswanti, C. Wen, E. Ivanova, C. Berndt, F. Malherbe, Vy T Pham, James Wang

{"title":"A review on bioactive porous metallic biomaterials","authors":"K. Mediaswanti, C. Wen, E. Ivanova, C. Berndt, F. Malherbe, Vy T Pham, James Wang","doi":"10.4172/1662-100X.1000104","DOIUrl":"https://doi.org/10.4172/1662-100X.1000104","url":null,"abstract":"Porous metallic biomaterials have been extensively studied for many bone tissue engineering applications because porous structures provided space for bone in-growth and vascularisation. Improvement on mechanical properties also leads to the increased popularity of porous materials for bone substitute applications, especially for load-bearing implants. However, they usually lack sufficient osseointegration for implant longevity. In addition, their biocompatibility is also an important concern in these applications due to adverse reactions of metallic ions with the surrounding tissues after these metallic ions are released from the implant surfaces. One consideration to accelerate the healing process is surface treatment, including application of bioactive coatings, e.g. hydroxyapatite and biomimetic creation of surface. Surface treatments on biomaterials will determine surface chemistry and topography, whereas these surface characteristics influence osseointegration process. To respond on the challenges of producing biocompatible and mechanical compatible biomaterials and lack of review studies on surface modifications on porous structures, a comprehensive literature review on surface modifications of various porous metallic materials is presented. This review covers various methods of surface treatment such as biomimetic, electrodeposition, alkali heat treatment, anodization and their effects on mechanical and structural properties which then provided insights into bone implants improvement studies. Biological responses (in vitro and In vivo) of porous material after surface treatment are thoroughly discussed.","PeriodicalId":15198,"journal":{"name":"Journal of Biomimetics, Biomaterials and Tissue Engineering","volume":"31 1","pages":"1-8"},"PeriodicalIF":0.0,"publicationDate":"2013-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84566997","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 42

In Vitro Degradation Behavior of Ternary Mg-Zn-Se and Mg-Zn-Cu Alloys as Biomaterials. 三元镁锌硒和镁锌铜合金作为生物材料的体外降解行为。

Journal of Biomimetics, Biomaterials and Tissue Engineering Pub Date : 2013-01-01 DOI: 10.4172/1662-100X.1000101

Dharam Persaud-Sharma, Noah Budiansky

引用次数: 10

Comparative Investigations of the Sandfishs β-Keratin (Reptilia: Scincidae: Scincus scincus). Part 2: Glycan-Based Friction Reduction 沙鱼β-角蛋白的比较研究(爬行纲:沙鱼科:沙鱼科)。第2部分:基于聚糖的摩擦减少

Journal of Biomimetics, Biomaterials and Tissue Engineering Pub Date : 2012-12-01 DOI: 10.4028/www.scientific.net/JBBTE.16.1

Konrad Staudt, W. Böhme, W. Baumgartner

{"title":"Comparative Investigations of the Sandfishs β-Keratin (Reptilia: Scincidae: Scincus scincus). Part 2: Glycan-Based Friction Reduction","authors":"Konrad Staudt, W. Böhme, W. Baumgartner","doi":"10.4028/www.scientific.net/JBBTE.16.1","DOIUrl":"https://doi.org/10.4028/www.scientific.net/JBBTE.16.1","url":null,"abstract":"The sandfish (Scincidae: Scincus scincus) is a lizard having outstanding skin properties. The scales show low friction behaviour and high abrasion resistance. After giving molecular support by DNA and protein analysis in Part 1 for increased glycosylation of the skins β-keratins, in this study the effect of glycans for friction reduction was investigated by (1) ammonium-based keratinolysis of skin exuviae and applying a β-keratin film on a glass surface and by (2) β-elimination based deglycosylation of β-keratins and immobilization of liberated glycans on a glass surface via silanisation. Both techniques resemble the natural model in the species investigated, the sandfish Scincus scincus and the Berber skink Eumeces schneideri. In the sandfish, a decreased friction coefficient was found by friction angle measurements, and a low adhesion force was measured by investigation with atomic force microscopy (AFM). These characteristics are possibly based by prevention of the formation of van der Waals bonds. This low adhesion force correlates with low friction and has a positive impact on abrasion resistance. A monosaccharide analysis confirmed the presence of carbohydrates.","PeriodicalId":15198,"journal":{"name":"Journal of Biomimetics, Biomaterials and Tissue Engineering","volume":"62 1","pages":"1 - 9"},"PeriodicalIF":0.0,"publicationDate":"2012-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74887751","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 12

Rib Design for Kirchhoff's Plate Inspired by Venation Configuration Kirchhoff板的肋骨设计灵感来自于脉状结构

Journal of Biomimetics, Biomaterials and Tissue Engineering Pub Date : 2012-12-01 DOI: 10.4028/www.scientific.net/JBBTE.16.43

Kai Xue, Yong Xin Li, Wei Wang

引用次数: 1

Effect of γ-Radiation on Thermal and Chemical Properties of Starch/Polystyrene Biopolymer Blend γ-辐射对淀粉/聚苯乙烯生物聚合物共混物热化学性能的影响

Journal of Biomimetics, Biomaterials and Tissue Engineering Pub Date : 2012-12-01 DOI: 10.4028/www.scientific.net/JBBTE.16.71

Jaheel K. Ahmed, Zuhair J. Abdul Amer, A. Majid

{"title":"Effect of γ-Radiation on Thermal and Chemical Properties of Starch/Polystyrene Biopolymer Blend","authors":"Jaheel K. Ahmed, Zuhair J. Abdul Amer, A. Majid","doi":"10.4028/www.scientific.net/JBBTE.16.71","DOIUrl":"https://doi.org/10.4028/www.scientific.net/JBBTE.16.71","url":null,"abstract":"In this study, the starch/polystyrene (PS) biopolymer blend is prepared by utilizing an in solution polymerization process. Two different ratios (50/50 and 80/20) of starch/PS were dissolved in toluene associated with mechanical mixing to maintain the homogeneity of the blend. Thereafter, the blend was exposed to γ-radiation using Cobalt 60 (Co60) at different dosing rates. The thermal and chemical properties were investigated by differential scanning calorimetry (DSC), Fourier transform infrared spectroscopy (FTIR), enzymatic degradation, and disclosure of starch by iodine, respectively. The deviation of glass transition temperature (Tg ( and the IR peaks indicate that a good interaction between starch and polystyrene was achieved in the blend. Exposure of the starch/PS blend to the α-amylase enzyme and to iodine demonstrated that the γ-rays have affected the amylopectin part with no distinct effect on the amylose part of the starch. Moreover, the colour has completely disappeared at 100 kGray irradiation dose since the blend becomes more responsive to enzymatic degradation at higher irradiation dose, which in turn causes in breaking down of the amylose part in the starch.","PeriodicalId":15198,"journal":{"name":"Journal of Biomimetics, Biomaterials and Tissue Engineering","volume":"32 1","pages":"71 - 81"},"PeriodicalIF":0.0,"publicationDate":"2012-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78414047","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2