Journal of Bone and Mineral Metabolism最新文献

{"title":"Author's response to the letter regarding 'Association of serum magnesium levels and calcimimetic use: fractures and cardiovascular events in Japanese haemodialysis patients'.","authors":"Tomohiro Saito, Masahide Mizobuchi, Kiryu Yoshida, Tadashi Kato, Kazuki Abe, Toshiaki Takezaki, Noriyuki Kato, Eisuke Inoue, Hiroaki Ogata, Fumihiko Koiwa, Hirokazu Honda","doi":"10.1007/s00774-026-01739-7","DOIUrl":"https://doi.org/10.1007/s00774-026-01739-7","url":null,"abstract":"","PeriodicalId":15116,"journal":{"name":"Journal of Bone and Mineral Metabolism","volume":" ","pages":""},"PeriodicalIF":2.9,"publicationDate":"2026-07-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148520360","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Response to the Letter to the Editor, Commentary on \"Incident subclinical vertebral fractures and health-related quality of life: JPOS cohort study\".","authors":"Mayumi Uesaka, Masami Hamada, Takahiro Tachiki, Yuho Sato, Kouji Tsuda, Asako Kudo, Kuniyasu Kamiya, Nami Imai, Akemi Nitta, Miho Tanaka, Kumiko Ohara, Naoyuki Takashima, Jun Kitagawa, Katsuyasu Kouda, Akemi Morita, Kazuhiro Uenishi, Etsuko Kajita, Koji Tamakoshi, Sadanobu Kagamimori, Junko Tamaki, Masayuki Iki","doi":"10.1007/s00774-026-01741-z","DOIUrl":"https://doi.org/10.1007/s00774-026-01741-z","url":null,"abstract":"","PeriodicalId":15116,"journal":{"name":"Journal of Bone and Mineral Metabolism","volume":" ","pages":""},"PeriodicalIF":2.9,"publicationDate":"2026-07-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148520351","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Toward skeletal phenotyping in magnesium-calcimimetic studies of hemodialysis.","authors":"Kaiquan Zhang, Meng Zhao, Dongdong Li","doi":"10.1007/s00774-026-01738-8","DOIUrl":"10.1007/s00774-026-01738-8","url":null,"abstract":"","PeriodicalId":15116,"journal":{"name":"Journal of Bone and Mineral Metabolism","volume":" ","pages":""},"PeriodicalIF":2.9,"publicationDate":"2026-07-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148497484","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comment on real-world persistence and interpretation of BMD outcomes in denosumab vs. alendronate therapy.","authors":"Yu Mori, Naoko Mori","doi":"10.1007/s00774-026-01694-3","DOIUrl":"10.1007/s00774-026-01694-3","url":null,"abstract":"","PeriodicalId":15116,"journal":{"name":"Journal of Bone and Mineral Metabolism","volume":" ","pages":"557-558"},"PeriodicalIF":2.9,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146029633","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"FLS shortens time to osteoporosis treatment and lowers 1-year refracture risk post proximal femoral fracture.","authors":"Masahito Taga, Kenji Hisa","doi":"10.1007/s00774-026-01731-1","DOIUrl":"10.1007/s00774-026-01731-1","url":null,"abstract":"<p><strong>Introduction: </strong>Proximal femoral fractures are highly prevalent in Japan, with over 200,000 cases annually and a rising trend. Fracture liaison service (FLS) interventions improve osteoporosis treatment initiation and reduce refracture rates. The content of FLS interventions varies by institution, and the effectiveness of our intervention remains unclear. The aim of this study was to evaluate the effectiveness of our FLS intervention in preventing fragility fractures within 1 year after proximal femoral fracture surgery.</p><p><strong>Materials and methods: </strong>A retrospective case-control study was performed on patients aged ≥ 50 undergoing surgery for proximal femoral fracture between February 2021 and January 2024. Patients were divided into non-FLS (pre-August 2022) and FLS groups. Data including demographics, comorbidities, fracture type, medication initiation, and refracture occurrence within 1 year were extracted. Statistical analyses involved Mann-Whitney U, χ2 tests, and Cox proportional hazards modeling.</p><p><strong>Results: </strong>Among 521 eligible patients, osteoporosis medication initiation within 3 months improved from 14% in the non-FLS group to 100% in the FLS group (p < 0.05). Time to medication initiation decreased from 20 to 12 days (p < 0.05). The refracture rate was significantly lower in the FLS group (1.8% vs. 5.7%, p < 0.05). Multivariate analysis showed FLS intervention significantly reduced refracture risk (HR 0.32, 95% CI 0.12-0.89, p = 0.03) and robust in sensitivity analyses for cognition, walking ability, and discharge destination.</p><p><strong>Conclusions: </strong>FLS intervention effectively reduced fragility fractures within 1 year postoperatively by enhancing early osteoporosis treatment initiation. Continued FLS programs and long-term follow-up are recommended to sustain benefits.</p>","PeriodicalId":15116,"journal":{"name":"Journal of Bone and Mineral Metabolism","volume":" ","pages":"530-535"},"PeriodicalIF":2.9,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147815214","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Treatment with romosozumab in patients with osteoporosis on maintenance hemodialysis.","authors":"Michael Pazianas, Paul D Miller","doi":"10.1007/s00774-026-01711-5","DOIUrl":"10.1007/s00774-026-01711-5","url":null,"abstract":"","PeriodicalId":15116,"journal":{"name":"Journal of Bone and Mineral Metabolism","volume":" ","pages":"559-560"},"PeriodicalIF":2.9,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147443816","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Response to the letter regarding \"Low BMI and postoperative outcomes in elderly hip fracture patients: a Japanese nationwide database study\".","authors":"Yu Mori, Kunio Tarasawa, Hidetatsu Tanaka, Ryuichi Kanabuchi, Naoko Mori, Kiyohide Fushimi, Toshimi Aizawa, Kenji Fujimori","doi":"10.1007/s00774-026-01693-4","DOIUrl":"10.1007/s00774-026-01693-4","url":null,"abstract":"","PeriodicalId":15116,"journal":{"name":"Journal of Bone and Mineral Metabolism","volume":" ","pages":"554-555"},"PeriodicalIF":2.9,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146100093","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comment on \"postoperative risks of type 2 diabetes in elderly hip fracture patients: a propensity score-matched study\".","authors":"Xin Zhou","doi":"10.1007/s00774-025-01680-1","DOIUrl":"10.1007/s00774-025-01680-1","url":null,"abstract":"","PeriodicalId":15116,"journal":{"name":"Journal of Bone and Mineral Metabolism","volume":" ","pages":"544-545"},"PeriodicalIF":2.9,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146010565","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Incident subclinical vertebral fractures and health-related quality of life: JPOS cohort study.","authors":"Mayumi Uesaka, Masami Hamada, Takahiro Tachiki, Yuho Sato, Kouji Tsuda, Asako Kudo, Kuniyasu Kamiya, Nami Imai, Akemi Nitta, Miho Tanaka, Kumiko Ohara, Naoyuki Takashima, Jun Kitagawa, Katsuyasu Kouda, Akemi Morita, Kazuhiro Uenishi, Etsuko Kajita, Koji Tamakoshi, Sadanobu Kagamimori, Junko Tamaki, Masayuki Iki","doi":"10.1007/s00774-026-01721-3","DOIUrl":"10.1007/s00774-026-01721-3","url":null,"abstract":"<p><strong>Introduction: </strong>Vertebral fractures are the most common osteoporotic fractures, yet approximately two-thirds of radiographically detectable fractures remain clinically unrecognized. The longitudinal impact of such subclinical vertebral fractures on health-related quality of life (HRQOL) is not fully clarified. This study examined whether incident subclinical vertebral fractures were associated with subsequent changes in HRQOL.</p><p><strong>Materials and methods: </strong>This study was nested within the Japanese Population-based Osteoporosis (JPOS) Cohort. Community-dwelling women aged ≥ 50 years without clinical fractures were included. Incident subclinical vertebral fractures, assessed by single-energy X-ray absorptiometry-based vertebral fracture assessment with morphometry, were the primary exposure. HRQOL was evaluated using Japanese SF-36® v2. General linear models estimated associations between incident fractures and follow-up SF-36® subscale scores, adjusting for baseline HRQOL and prespecified covariates. Sensitivity analyses excluding participants with pre-baseline subclinical vertebral fractures or with anti-osteoporosis medication were performed.</p><p><strong>Results: </strong>Of 344 participants, 53 (15.4%) developed incident subclinical vertebral fractures. Baseline SF-36® standardized subscale scores did not differ between groups. At follow-up, women with incident fractures had significantly lower physical functioning and social functioning scores. After multivariable adjustment, social functioning remained significantly lower in the fracture group (false discovery rate-adjusted p = 0.028). Social functioning declined progressively with increasing fracture number and was significantly lower in lumbar fractures. Sensitivity analyses yielded consistent results with primary analyses.</p><p><strong>Conclusions: </strong>Incident subclinical vertebral fractures among community-dwelling Japanese women were independently associated with clinically meaningful declines in social functioning, suggesting the importance of early identification to prevent deterioration in HRQOL.</p>","PeriodicalId":15116,"journal":{"name":"Journal of Bone and Mineral Metabolism","volume":" ","pages":"489-500"},"PeriodicalIF":2.9,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147654214","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Author's Response to letter to the editor \"Commentary on: the effects of sequential therapy using anti-resorptive agents after administering once-weekly teriparatide or twice-weekly teriparatide\" (JBMM-D-26-00062).","authors":"Hidehiro Matsumoto, Manabu Tsukamoto, Nobukazu Okimoto, Satoshi Ikeda, Masahiro Tanaka, Mitsugu Takahashi, Yoshiaki Ikejiri, Fumihiro Oha, Satoshi Mizuno, Keiichi Shigenobu, Akinori Sakai, Junichi Takada","doi":"10.1007/s00774-026-01717-z","DOIUrl":"10.1007/s00774-026-01717-z","url":null,"abstract":"","PeriodicalId":15116,"journal":{"name":"Journal of Bone and Mineral Metabolism","volume":" ","pages":"564-565"},"PeriodicalIF":2.9,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147503849","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}