Association of the weight-adjusted waist index with mortality in osteoporotic patients.

IF 2.4 3区医学 Q3 ENDOCRINOLOGY & METABOLISM

Journal of Bone and Mineral Metabolism Pub Date : 2025-03-21 DOI:10.1007/s00774-025-01594-y

Qian Lyu, Linxiao Ma, Huijie Liu, Haiyan Shao

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引用次数: 0

Abstract

Introduction: The prevalence of osteoporosis (OP) is steadily rising, leading to a higher risk of mortality. This study assessed the impact of the Weight-Adjusted Waist Index (WWI) on osteoporosis-related mortality.

Materials and methods: Data from NHANES 2005-2010, 2013-2014, and 2017-2018 were analyzed to evaluate the relationship between WWI and mortality in osteoporotic patients using weighted proportional hazards model and Kaplan-Meier survival analysis. A subgroup analysis was performed to ensure the stability of the findings.

Results: The study included 1324 participants. The findings indicated a positive correlation between WWI and OP (OR 1.65, 95% CI 1.45-1.89). Among patients with OP, WWI showed a positive association with all-cause mortality (HR 1.28, 95% CI 1.10-1.48). There was no observed correlation between varying WWI levels and mortality due to cardiovascular disease or cancer.

Conclusions: Maintaining a lower WWI is associated with a reduced risk of all-cause mortality among individuals with OP.

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体重调整后腰围指数与骨质疏松症患者死亡率的关系。

导读：骨质疏松症（OP）的患病率正在稳步上升，导致较高的死亡风险。本研究评估了体重调整腰围指数（WWI）对骨质疏松相关死亡率的影响。材料与方法：采用加权比例风险模型和Kaplan-Meier生存分析，分析NHANES 2005-2010年、2013-2014年和2017-2018年的数据，评估一战与骨质疏松症患者死亡率的关系。进行亚组分析以确保结果的稳定性。结果：研究纳入1324名参与者。研究结果表明，第一次世界大战与OP呈正相关（OR 1.65, 95% CI 1.45-1.89）。在OP患者中，WWI与全因死亡率呈正相关（HR 1.28, 95% CI 1.10-1.48）。没有观察到不同的一战水平与心血管疾病或癌症导致的死亡率之间的相关性。结论：维持较低的WWI与OP患者全因死亡风险降低相关。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Journal of Bone and Mineral Metabolism 医学-内分泌学与代谢

CiteScore

6.30

自引率

3.00%

发文量

审稿时长

6-12 weeks

期刊介绍： The Journal of Bone and Mineral Metabolism (JBMM) provides an international forum for researchers and clinicians to present and discuss topics relevant to bone, teeth, and mineral metabolism, as well as joint and musculoskeletal disorders. The journal welcomes the submission of manuscripts from any country. Membership in the society is not a prerequisite for submission. Acceptance is based on the originality, significance, and validity of the material presented. The journal is aimed at researchers and clinicians dedicated to improvements in research, development, and patient-care in the fields of bone and mineral metabolism.