{"title":"Do we need animal models to better understand the molecular basis of internet use disorders?","authors":"Christian Montag","doi":"10.1556/2006.2025.00464","DOIUrl":"https://doi.org/10.1556/2006.2025.00464","url":null,"abstract":"<p><p>Studying the molecular basis of Internet Use Disorders is still in its beginnings. Animal research relying on an operant light self-administration paradigm proposed by Tam et al. (2025) might provide much needed insights helping to elucidate the molecular basis underlying excessive online behavior. Despite the potential of this approach, also ethical aspects of such research need to be considered. Finally, it is not clear to what extent observations using operant light self-administration paradigms in animals can be really transferred to humans.</p>","PeriodicalId":15049,"journal":{"name":"Journal of Behavioral Addictions","volume":" ","pages":""},"PeriodicalIF":6.2,"publicationDate":"2026-06-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148156759","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Yuan Feng, Xindi Lin, Yuanyuan Li, He Li, Shirong Zhu, Yinchu Cheng, Jiani Wu, Valeria Sacca, Winson Fu Zun Yang, Bichuan Ren, Sisi Jiang, Chengcheng Pu
{"title":"Striato-limbic and frontoparietal dysfunction underlying imbalance of reward-motivation and cognitive control in compulsive sexual behaviour disorder: A neuroimaging meta-analysis.","authors":"Yuan Feng, Xindi Lin, Yuanyuan Li, He Li, Shirong Zhu, Yinchu Cheng, Jiani Wu, Valeria Sacca, Winson Fu Zun Yang, Bichuan Ren, Sisi Jiang, Chengcheng Pu","doi":"10.1556/2006.2025.00563","DOIUrl":"10.1556/2006.2025.00563","url":null,"abstract":"<p><strong>Background: </strong>Compulsive sexual behavior disorder (CSBD) involves uncontrollable sexual urges and behaviors that cause distress or functional impairment. Although classified as an impulse control disorder in ICD-11, its neurobiological basis and cognitive deficits remain poorly understood. Advances in large language models (LLMs) enable scalable literature parsing and multimodal neuroimaging synthesis. This study applied an LLM-based framework for coordinate-based meta-analysis and functional decoding to generate a brain-cognition mapping of CSBD that links neurobiological alterations with cognitive dysfunctions.</p><p><strong>Methods: </strong>Relevant structural and functional neuroimaging studies of CSBD were identified through semantic screening in Neurosynth Compose. Coordinates were extracted and synthesized using Multi-level Kernel Density Analysis (MKDA-χ2), with subgroup analyses conducted by study characteristics. The resulting brain maps were then functionally annotated in NeuroVault to identify associated cognitive, emotional, motivational, and behavioral dimensions.</p><p><strong>Results: </strong>Meta-analysis revealed consistent abnormalities in the left hippocampus, inferior parietal lobule, precentral gyrus, putamen, and angular gyrus, and in the right globus pallidus and supramarginal gyrus. Task-based studies mainly implicated the inferior parietal lobule, hippocampus, and globus pallidus, whereas resting-state studies indicated cerebellar involvement. In European samples, abnormalities appeared in the globus pallidus, precentral gyrus, and hippocampus, while East Asian samples showed alterations in the inferior parietal lobule and precuneus. Functional decoding linked these patterns to motivational delay, anxiety, social interaction, and response inhibition.</p><p><strong>Conclusion: </strong>CSBD may reflect a dual dysregulation mechanism involving hyperactivation of the striato-limbic reward-motivation circuitry and impaired top-down control within the frontoparietal network, together promoting persistent and compulsive sexual behaviors.</p>","PeriodicalId":15049,"journal":{"name":"Journal of Behavioral Addictions","volume":" ","pages":"567-581"},"PeriodicalIF":6.3,"publicationDate":"2026-05-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13371736/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148030663","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Yasin Kavla, Süleyman Agah Demirgül, Tuğba Bozdemir, Dilara Demircan, Büşra Yamanel-Özsoy, Hasan Durmuş, Eren Murat Dinçer, Gökhan Umut, Zsolt Demetrovics, Marc N Potenza, Mehmet Dinç
{"title":"A comparative analysis of sociodemographic and clinical characteristics of gambling disorder by sex among treatment-seeking individuals: A national sample from Türkiye.","authors":"Yasin Kavla, Süleyman Agah Demirgül, Tuğba Bozdemir, Dilara Demircan, Büşra Yamanel-Özsoy, Hasan Durmuş, Eren Murat Dinçer, Gökhan Umut, Zsolt Demetrovics, Marc N Potenza, Mehmet Dinç","doi":"10.1556/2006.2026.00083","DOIUrl":"10.1556/2006.2026.00083","url":null,"abstract":"<p><strong>Background and aims: </strong>Gambling disorder (GD) is a growing public health concern, with emerging evidence suggesting potential sex differences in clinical presentation, gambling preferences, and treatment-seeking patterns. Furthermore, non-Western countries/cultures and women's clinical populations are understudied. Therefore, this study aimed to examine sex-related sociodemographic characteristics, gambling behaviors, and psychiatric symptoms among treatment-seeking individuals with GD in Türkiye.</p><p><strong>Methods: </strong>Data from 12,505 treatment-seeking individuals who registered for Green Crescent Counselling Center between 2021 and 2024 were analyzed. A total of 330 women participants who met the inclusion criteria were identified and compared with a sample of 990 men participants (matched on age, marital status, and education). Sociodemographic and clinical features, gambling preferences, and psychiatric symptoms were compared between groups.</p><p><strong>Results: </strong>A notable increase in the number and proportion of women seeking-treatment for GD was observed between 2021 and 2024. Women reported beginning gambling at a later age and engaging in it for a shorter duration compared to men. They showed a distinct gambling pattern, with a strong preference for online casino games, whereas men primarily engaged in sports betting. Women also exhibited higher rates of co-occurring psychiatric concerns, including depression, anxiety, PTSD, along with greater impulsivity.</p><p><strong>Discussion and conclusions: </strong>Our findings highlight meaningful sex-related differences in the clinical presentation and gambling behaviors of treatment-seeking individuals with GD. The sizable representation of women suggests the need for sex-sensitive prevention and intervention strategies. Tailored approaches that address co-occurring psychiatric concerns, gambling preferences, and speculative motivations, may enhance treatment outcomes and inform future service provision in the treatment of GD, particularly for women.</p>","PeriodicalId":15049,"journal":{"name":"Journal of Behavioral Addictions","volume":" ","pages":"886-899"},"PeriodicalIF":6.3,"publicationDate":"2026-05-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13371746/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148030636","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Addendum to: Instagram addiction and the big five of personality: The mediating role of self-liking.","authors":"Kağan Kırcaburun, Mark D Griffiths","doi":"10.1556/2006.2026.11111","DOIUrl":"10.1556/2006.2026.11111","url":null,"abstract":"","PeriodicalId":15049,"journal":{"name":"Journal of Behavioral Addictions","volume":" ","pages":"921"},"PeriodicalIF":6.3,"publicationDate":"2026-05-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13373958/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147987534","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Animal models relevant to digital technology-based disorders.","authors":"Shu K E Tam, Benjamin Becker","doi":"10.1556/2006.2025.00307","DOIUrl":"10.1556/2006.2025.00307","url":null,"abstract":"<p><p>Animal models utilizing Pavlovian and instrumental conditioning paradigms have advanced our understanding of the mechanisms underlying drug addiction and certain behavioral addiction such as gambling disorder, but so far there is no animal model for digital technology-based disorders such as (Internet) gaming disorder, which is an emerging issue in our digital society. Casile et al. (2025) introduced a rat touchscreen paradigm recapitulating several key phenotypes relevant to gaming disorder, including preoccupation with the touchscreen and behavioral persistence despite non-reinforcement. However, the paradigm's reliance on food reinforcers limits translational relevance. We suggest integrating Casile et al. touchscreen paradigm with non-food operant paradigms (e.g., light self-administration), to dissociate any intrinsic reinforcing effects of touchscreen interaction and response-contingent sensory feedback from hedonic values of food. Potential differences in sensory habituation between rats and mice highlight the need for cross-species comparisons, to distinguish species-specific responses from general behavioral mechanisms in non-human animals and humans. While animal models cannot fully capture the multifaceted nature of digital technology-based disorders, they provide simplified models to examine how behavioral persistence can be shaped and maintained by non-food, non-drug reinforcement contingencies without the influence of cultural and social factors.</p>","PeriodicalId":15049,"journal":{"name":"Journal of Behavioral Addictions","volume":" ","pages":"525-532"},"PeriodicalIF":6.3,"publicationDate":"2026-05-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13371727/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147981952","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A qualitative analysis of addiction components in rhinitis medicamentosa.","authors":"Máté Kapitány-Fövény","doi":"10.1556/2006.2025.00530","DOIUrl":"https://doi.org/10.1556/2006.2025.00530","url":null,"abstract":"<p><p>This commentary evaluates Lakatos et al.'s qualitative study on nasal spray addiction within rhinitis medicamentosa (RM), applying Griffiths' addiction component model. While evidence remains insufficient for formal diagnostic inclusion, the study identifies behavioral and psychological features paralleling core addiction criteria. Case reports and user narratives provide additional support, though counter-evidence persists. Conceptual and methodological challenges highlight the need for research addressing clinical relevance, theoretical embedding, and taxonomic plausibility. Despite limited empirical validation, the significant distress and functional impairment reported by affected individuals underscore the importance of recognizing and addressing this emerging issue.</p>","PeriodicalId":15049,"journal":{"name":"Journal of Behavioral Addictions","volume":" ","pages":""},"PeriodicalIF":6.2,"publicationDate":"2026-05-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147963931","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Chatbot relational dependence and psychosis risk: Conversational artificial intelligence as a potential behavioral addiction context.","authors":"Tamás Treuer, Adrienne Incze","doi":"10.1556/2006.2026.00080","DOIUrl":"10.1556/2006.2026.00080","url":null,"abstract":"<p><p>Conversational artificial intelligence (AI) chatbots are increasingly used for emotional support, companionship, and psychological reflection. Their capacity to simulate attentiveness, empathy, and conversational continuity may shift technology use from instrumental interaction toward relational engagement. Emerging clinical observations suggest that intensive chatbot use may, in vulnerable individuals, contribute to psychiatric destabilization, including reinforcement of maladaptive beliefs and, in rare cases, psychotic symptoms. This viewpoint proposes that conversational AI engagement can be conceptualized within a behavioral addiction framework capable of interacting with psychosis vulnerability without requiring biological intoxication. An illustrative clinical case is presented involving a young adult woman who developed paranoid psychosis following escalating emotional reliance on a chatbot, including a fixed delusional belief that her husband was covertly communicating through the system. Potential mechanisms include persistent algorithmic attention, sleep disruption, social withdrawal, cognitive reinforcement loops, and displacement of attachment needs. Although causal relationships cannot be inferred from current evidence, systematic assessment of intensive AI engagement may become clinically relevant in behavioral addiction psychiatry and early psychosis evaluation. Further empirical research is needed to clarify prevalence, mechanisms, and clinical implications of AI-mediated relational dependence.</p>","PeriodicalId":15049,"journal":{"name":"Journal of Behavioral Addictions","volume":" ","pages":"533-539"},"PeriodicalIF":6.3,"publicationDate":"2026-05-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13371778/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147963864","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Davide Marengo, Bruno Schivinski, Halley M Pontes, Christian Montag
{"title":"The role of videogame genre and platform in gaming disorder tendencies: A large-scale world-wide study of gamers' preferences.","authors":"Davide Marengo, Bruno Schivinski, Halley M Pontes, Christian Montag","doi":"10.1556/2006.2026.00022","DOIUrl":"10.1556/2006.2026.00022","url":null,"abstract":"<p><strong>Background and aims: </strong>Literature suggests that individual differences in tendencies toward gaming disorder (GD) may be associated with characteristics of the video games people prefer. We examined how game genre, multiplayer capability, and platform relate to GD tendencies assessed using both APA (DSM-5) and WHO (ICD-11) frameworks in a large international sample of gamers.</p><p><strong>Methods: </strong>We analyzed cross-sectional online data from 116,047 gamers. Participants completed validated measures of GD symptoms aligned with DSM-5 and ICD-11 and reported the genre, multiplayer capability, and platform of their currently preferred game. Associations were examined using bivariate and multivariate analyses. We additionally applied a Random Forest model to evaluate the predictive contribution of game-related variables to GD scores.</p><p><strong>Results: </strong>GD levels were highest among participants preferring games with multiplayer capabilities, while positive associations with shooter and casual games were particularly evident among console users. In contrast, puzzle, platformer, and board games showed negative associations with GD scores. Players preferring desktop or laptop computers reported higher GD scores than those favoring consoles or small devices. In Random Forest models, game genre and multiplayer capability were modestly predictive of GD scores (R ≈ .08-.15) with predictive accuracy being higher for participants who used console and desktop computers and lowest among small-device users.</p><p><strong>Conclusions: </strong>Multiplayer capability and preferred genre were consistently related to GD tendencies across DSM-5 and ICD-11 measures. However, these variables alone offered limited predictive power, indicating that GD risk is only partly explained by game characteristics and likely depends on broader individual and contextual factors.</p>","PeriodicalId":15049,"journal":{"name":"Journal of Behavioral Addictions","volume":" ","pages":"735-745"},"PeriodicalIF":6.3,"publicationDate":"2026-05-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13371733/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147972793","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Operant light self-administration may not be reinforcing beyond homeostasis, and habit learning in rodents may not translate well to human addiction.","authors":"Richard J Tunney","doi":"10.1556/2006.2025.00504","DOIUrl":"https://doi.org/10.1556/2006.2025.00504","url":null,"abstract":"<p><p>Translational animal models are central to understanding both substance and behavioural addictions. This commentary evaluates the proposal made by Tam and colleagues (Tam et al. 2025) that operant light self-administration in mice may serve as a rodent translational model for digital technology-based disorders. While the habit theory of addiction provides a compelling framework for understanding the transition from goal-directed to compulsive behaviour in rodents, evidence from human studies challenge its generalisability. Also considered is the proposition light can function as a primary reinforcer capable of supporting habit formation and draws parallels with the reinforcing properties of short-form video content on platforms such as TikTok and Instagram. Although promising as a model for studying visual reinforcement, the approach does not account for broader psychosocial and individual difference factors contributing to addiction. Research should identify the specific visual features that drive compulsive engagement and clarify whether similar neural mechanisms underlie both light-based and digital technology-related reinforcement.</p>","PeriodicalId":15049,"journal":{"name":"Journal of Behavioral Addictions","volume":" ","pages":""},"PeriodicalIF":6.2,"publicationDate":"2026-05-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147972738","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Has light reinforcing effects in humans and may contribute to the development of problematic usage of the internet and digital-based behavioral addictions?","authors":"Elisa Wegmann, Sabine Steins-Loeber","doi":"10.1556/2006.2025.00417","DOIUrl":"https://doi.org/10.1556/2006.2025.00417","url":null,"abstract":"<p><p>This commentary complements the arguments by Tam et al. (2025) and offers a comprehensive approach when considering light conditioning in the context of the development and maintenance of problematic Internet use. Thereby, we illustrate the impact of light on humans also within the context of theoretical considerations and empirical studies. We agree with Tam et al. (2025) that there is a need for a better understanding of habit formation within addictive behaviors and we acknowledge the empirical challenges which are proposed in the article mentioned. At the same time, this commentary emphasizes that light should not be considered as an isolated reinforcer, but rather as a complementary component of other conditioned and cognitive tendencies (e.g., use expectancies), as well within the interplay of further processes in addiction research such as craving, attentional biases, and self-control abilities.</p>","PeriodicalId":15049,"journal":{"name":"Journal of Behavioral Addictions","volume":" ","pages":""},"PeriodicalIF":6.2,"publicationDate":"2026-05-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147941715","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}