Journal of Applied Biotechnology & Bioengineering最新文献_第2页

Bioengineering of nano drug delivery compound to enhance the bioavailability of selected bioactive compound 纳米给药化合物的生物工程，以提高选定的生物活性化合物的生物利用度

Journal of Applied Biotechnology & Bioengineering Pub Date : 2021-06-28 DOI: 10.15406/jabb.2021.08.00259

S. Maran

引用次数: 0

Impact of default rate of antiretroviral use on viral load among HIV/AIDS patients in Tamale and Sunyani Tamale和Sunyani地区HIV/AIDS患者未及时使用抗逆转录病毒药物对病毒载量的影响

Journal of Applied Biotechnology & Bioengineering Pub Date : 2021-06-15 DOI: 10.15406/jabb.2021.08.00258

James Abugri

{"title":"Impact of default rate of antiretroviral use on viral load among HIV/AIDS patients in Tamale and Sunyani","authors":"James Abugri","doi":"10.15406/jabb.2021.08.00258","DOIUrl":"https://doi.org/10.15406/jabb.2021.08.00258","url":null,"abstract":"Background: Highly Active Antiretroviral Therapy (HAART) for persons living with HIV/AIDS (PLWHA) is the gold standard for the management of HIV patients. Purportedly, patients who are not on HAART or defaulted from its use have adverse effects compared to those who adhere to the intake of HAART. Compliant individuals have improved quality of life and show healthy hematological parameters and HIV load as compared to HAART naïve individuals and defaulters. Supplementary and supportive treatment is crucial in HIV/AIDS patients on patients on antiretroviral therapy? Objective: This study was conducted to assess the consistency and default of HAART intake and other supportive treatments and its relationship with viral load on hematological parameters in two different geographical sites. Methods: Ethical clearance was obtained from Navrongo Health Research Centre. Questionnaires were administered to participants for their consent, demographic data, consistency of taking antiretrovirals, and types of antiretrovirals used. Full blood count and HIV load tests were carried out using Urit 5250 and Cobas Taqman / Cobas ampliprep fully automated analysers respectively. Results: Defaulters had a significant (p value=0.003) rise in their viral load (845334.38±409285.62) copies/mL in comparison to adherents in HAART intake 49571.69±30548.89) copies/mL. The hemoglobin level (10.51±0.60 g/dL) of defaulters was significantly (p-value = 0.007) lower than that of adherent (12.04±0.17 g/dL). The default rates in the two study sites were close (9.8% in Sunyani and 9.4% in Tamale). Conclusion: Antiretroviral default does not only lead to an increase in HIV load but also causes a reduction in hemoglobin levels. Hematinics supplementation therapy may help normalize hematological parameters in HIV infection","PeriodicalId":15033,"journal":{"name":"Journal of Applied Biotechnology & Bioengineering","volume":"601 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-06-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77330620","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

The green bulkhead: a vertical wetland design for urban harbors 绿色舱壁:城市港口的垂直湿地设计

Journal of Applied Biotechnology & Bioengineering Pub Date : 2021-05-20 DOI: 10.15406/jabb.2021.08.00256

P. May, M. Lagomarsino, P. Kangas

{"title":"The green bulkhead: a vertical wetland design for urban harbors","authors":"P. May, M. Lagomarsino, P. Kangas","doi":"10.15406/jabb.2021.08.00256","DOIUrl":"https://doi.org/10.15406/jabb.2021.08.00256","url":null,"abstract":"In urban harbors there is a reliance on the “gray infrastructure” of armored bulkheads along shorelines. While this form of shoreline technology provides stability and eliminates erosion, it limits shoreline biodiversity and lacks aesthetic value. In this paper, a living shoreline concept, termed the Green Bulkhead, is described and demonstrated. This is a kind of artificial vertical wetland with plants grown in a porous plastic fabric that is draped over the surface of an existing bulkhead. The system is irrigated with water that is pumped from the harbor. Several alternate designs have been tested for different medium types, planting patterns and water pumping regimes. It is proposed that the green bulkhead system can provide limited treatment wetland services in an urban setting where cost-effective water quality management options are minimal. Testing found that high percentages of sediment were retained within the matrix of the different media. The system has aesthetic benefits by “greening” the harbor environment with wetland plants and, because of its vertical orientation, it can be managed adaptively for sea level rise. This work is a report of an on-going ecological engineering project with demonstrations along the Baltimore, Maryland Inner Harbor and the Anacostia Waterfront in Washington, DC.","PeriodicalId":15033,"journal":{"name":"Journal of Applied Biotechnology & Bioengineering","volume":"23 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-05-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79293464","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

TOR regulates plant development and plantmicroorganism interactions TOR调控植物发育和植物微生物相互作用

Journal of Applied Biotechnology & Bioengineering Pub Date : 2021-05-07 DOI: 10.15406/jabb.2021.08.00255

Elisa Carrillo-Flores, D. Pazos-Solis, Frida Paola Diaz-Bellacetin, G. Fierros-Romero, E. Beltrán-Peña, María Elena Mellado-Rojas

引用次数: 0

Decentralized biotechnologies in production-use networks of biological control agents 生物防治剂生产使用网络中的分散生物技术

Journal of Applied Biotechnology & Bioengineering Pub Date : 2021-04-27 DOI: 10.15406/jabb.2021.08.00254

L. Vázquez

引用次数: 0

Prevalence of hearing impairment in patients with diabetes mellitus at tertiary care center of Nepal 尼泊尔三级保健中心糖尿病患者听力损害的患病率

Journal of Applied Biotechnology & Bioengineering Pub Date : 2021-04-26 DOI: 10.15406/JABB.2021.08.00253

N. Bhat, N. Mahotra, L. Shrestha, T. Shrestha, P. Tripathi, Mudit Gupta, Sanyukta Gurung

{"title":"Prevalence of hearing impairment in patients with diabetes mellitus at tertiary care center of Nepal","authors":"N. Bhat, N. Mahotra, L. Shrestha, T. Shrestha, P. Tripathi, Mudit Gupta, Sanyukta Gurung","doi":"10.15406/JABB.2021.08.00253","DOIUrl":"https://doi.org/10.15406/JABB.2021.08.00253","url":null,"abstract":"Background: Diabetes mellitus is a chronic, systemic and metabolic disorder known to affect almost every organ due to its unequivocal complications. The auditory organ is often affected but usually ignored complications of diabetes mellitus. With the rise in the prevalence of diabetes mellitus and hearing impairment in developing countries, it becomes a crucial public health issue if both of them are found to be associated. Objective: To find the prevalence of hearing impairment in diabetic patients. Materials and Methods: This was a cross-sectional study conducted at the Department of Clinical Physiology in collaboration with the Department of General Practice and Emergency Medicine and the Department of Otorhinolaryngology- Head and Neck Surgery, Tribhuvan University Teaching Hospital. After applying exclusion criteria, 55 subjects were recruited for the study. Pure Tone Audiometry, a non-invasive test was used to assess hearing threshold in this study. Audiogram findings of diabetics were then analyzed. Results: Outcomes of the tests revealed that 17 (30%) of subjects with diabetes mellitus had hearing loss, out of which 13 had mild hearing loss. A significantly positive correlation was found between age and hearing threshold at every frequency. Higher frequencies were found to be more affected. The best cut-off age for onset of hearing loss in diabetics was found to be 51.50 years. Conclusion: Current study suggests a 30% prevalence of hearing loss in diabetes mellitus. We observed hearing loss more among the elderly at higher frequencies","PeriodicalId":15033,"journal":{"name":"Journal of Applied Biotechnology & Bioengineering","volume":"120 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-04-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86165972","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Synthesis and characterization of aluminum dope zinc sulfide (Al:ZnS) thin films by chemical bath deposition techniques 化学浴沉积法制备铝掺杂硫化锌(Al:ZnS)薄膜

Journal of Applied Biotechnology & Bioengineering Pub Date : 2021-04-12 DOI: 10.15406/jabb.2021.08.00252

Gemechis Megersa Jigi, Tizazu Abza, Asnake Girma

{"title":"Synthesis and characterization of aluminum dope zinc sulfide (Al:ZnS) thin films by chemical bath deposition techniques","authors":"Gemechis Megersa Jigi, Tizazu Abza, Asnake Girma","doi":"10.15406/jabb.2021.08.00252","DOIUrl":"https://doi.org/10.15406/jabb.2021.08.00252","url":null,"abstract":"A well adherent thin films of Aluminum doped zinc sulphide (Al:ZnS) has been deposited on silica glass substrates using acidic chemical bath deposition (CBD) containing zinc acetate, Aluminum Chloride, and thioacetamide. EDTA was used as complexing agent to control the free ion concentration of the thin films. Aluminum concentrations were doped by 2%, 4%, and 6% while keeping other deposition parameters constant as deposited Al:ZnS thin films. The samples were characterized by BrukerD8 diffractometer with cuKα (λ=1.5406A˚) radiation working at 40 mA and 40 kV, JOEL-2300 Analysis Station Scanning electron microscope (SEM), and Perkin Elmer Lambda 950 UV-vis/NIR spectrophotometer. The structural characterization of the samples show that no intense peaks were observed indicating the amorphous nature of the films. The surface morphology studies of as deposited Al:ZnS thin films shown the films were uniform, dense, and composed of spherical shaped grains. EDAX shows the elemental composition of Zn, S, and Al. The ratios of Zn/S in Stoichiometric even though the concentration of Aluminum is increased. Optical absorbance of the films decreased with increase Aluminum concentration. The large band gap makes them good materials for application as a window layer for solar cells.","PeriodicalId":15033,"journal":{"name":"Journal of Applied Biotechnology & Bioengineering","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-04-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85400126","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 6

Effectiveness of isolated compound from Aloe barbadensis Miller and its formulated ointment against bacteria and fungi 从芦荟中分离的化合物及其配制的药膏对细菌和真菌的有效性

Journal of Applied Biotechnology & Bioengineering Pub Date : 2021-04-02 DOI: 10.15406/JABB.2021.08.00251

M. Donkor, Ngmenpone Kuubabongnaa, A. Donkor

{"title":"Effectiveness of isolated compound from Aloe barbadensis Miller and its formulated ointment against bacteria and fungi","authors":"M. Donkor, Ngmenpone Kuubabongnaa, A. Donkor","doi":"10.15406/JABB.2021.08.00251","DOIUrl":"https://doi.org/10.15406/JABB.2021.08.00251","url":null,"abstract":"Ethnomedicinally, the family Liliaceae is prominent in controlling skin, wound and fungal infections. A carboxylic fatty acid derivative has been isolated from Aloe vera leaves and its structure was elucidated on the basis of NMR and FT-IR analysis. The compound was formulated as ointment with the aid of polymer based delivery agent. The ointment and the uncontaminated fatty acid have been scrutinized aimed at their anti-infectious potential. Individually, the pure compound and the formulated ointment exhibited growth inhibitory activity against Pseudomonas aeruginosa, Escherichia coli, Staphylococcus aureus, Klebsiella pneumoniae, Candida albicans and Talaromyces flavus. Minimum inhibitory concentration (MIC) values were found to be appreciably low, ranging between 0.30 and 2.50 mg/ml. The formulated ointment displayed highly significant inhibitory activities against all six pathogens compared to the unformulated compound. The MIC values of the ointment ranged between 0.08 and 1.25 mg/g. The in vitro antibiotic activity studies discovered that, both the pure compound and the formulated ointment showed potency against the selected multi-resistant microorganisms tested in the current work. These findings suggest that the isolated carboxylic acid derivative may be beneficial in the discovery of antibiotics highly potent against drug-resistant pathogens. Furthermore, it may add to the improvement of preservatives in the food industry. Lastly, it could be considered as new source of natural antibiotics in the pharmaceutical industry.","PeriodicalId":15033,"journal":{"name":"Journal of Applied Biotechnology & Bioengineering","volume":"7 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-04-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85175418","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Partial reduction of air pollution in India during COVID-19 lockdown 在2019冠状病毒病封锁期间，印度的空气污染部分减少

Journal of Applied Biotechnology & Bioengineering Pub Date : 2021-03-23 DOI: 10.15406/jabb.2021.08.00250

G. S. Sree, Kapilavayi Venkata, B. Ranjitha, Boggu Jagan Mohan Reddy

引用次数: 1

Influential ethical aspects of Covid19 in multidimensions 多维度影响covid - 19的伦理方面

Journal of Applied Biotechnology & Bioengineering Pub Date : 2021-02-26 DOI: 10.15406/JABB.2021.08.00248

M. Rajan, M. Rani

{"title":"Influential ethical aspects of Covid19 in multidimensions","authors":"M. Rajan, M. Rani","doi":"10.15406/JABB.2021.08.00248","DOIUrl":"https://doi.org/10.15406/JABB.2021.08.00248","url":null,"abstract":"The COVID19 pandemic poses an exceptional challenge for humanity. Because public behavior is key to curbing the pandemic at an early stage, it is important for social psychological researchers to use their knowledge to promote behaviors that help manage the crisis. Here, we identify human values as particularly important in driving both behavioral compliance to government guidelines and promoting prosocial behaviors to alleviate the strains arising from a prolonged pandemic. Existing evidence demonstrates the importance of human values, and the extent to which fellow citizens, for tackling the COVID19 crisis, share them. Individuals who attach higher importance to self‐transcendence (e.g., responsibility) and conservation (e.g., security) values are likely to be more compliant with COVID19 behavioral guidelines and to help others who are struggling with the crisis. Further, believing that fellow citizens share one's values has found to elicit a sense of connectedness that may be crucial in promoting collective efforts to contain the pandemic. The abstract nature of values, and cross-cultural agreement on their importance, suggests that they are ideally suited to developing and tailoring effective, global interventions to combat this pandemic","PeriodicalId":15033,"journal":{"name":"Journal of Applied Biotechnology & Bioengineering","volume":"16 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-02-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80041006","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0