Journal of Applied Clinical Medical Physics最新文献

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Benchmarking MapRT and first clinical experience: A novel solution for collision-free non-coplanar treatment planning 对标MapRT和首次临床经验:无碰撞非共面治疗计划的新解决方案。
IF 2 4区 医学
Journal of Applied Clinical Medical Physics Pub Date : 2025-02-05 DOI: 10.1002/acm2.14572
Mathieu Gonod, Ilyas Achag, Jad Farah, Léone Aubignac, Igor Bessieres
{"title":"Benchmarking MapRT and first clinical experience: A novel solution for collision-free non-coplanar treatment planning","authors":"Mathieu Gonod,&nbsp;Ilyas Achag,&nbsp;Jad Farah,&nbsp;Léone Aubignac,&nbsp;Igor Bessieres","doi":"10.1002/acm2.14572","DOIUrl":"10.1002/acm2.14572","url":null,"abstract":"<p>In recent years, complex re-irradiations and stereotactic treatments have triggered the use of non-coplanar treatments for better dose conformality, entailing risks of collision between the machine and the patient, couch, or immobilization device. To ensure the plans deliverability without collisions, time-consuming actions are typically performed, including dry runs, in-room couch rotations, and beam configuration tests during planning. To overcome these challenges, a new tool called MapRT (VisionRT Ltd., London, UK) was developed. MapRT predicts a clearance map based on a patients' 3D model (acquired with dedicated cameras at the CT simulation) and pre-established machine models. This work evaluates the accuracy of MapRT using a 30 × 35 × 40 cm<sup>3</sup> phantom and 64 gantry/couch collision coordinates on a Truebeam Linac (Varian, Palo Alto, USA). Collision coordinates were recorded for gantry and couch rotations. The agreement of real collision coordinates and MapRT's predictions was evaluated for different buffer margins around the couch/patient models customizable in MapRT. Results of the first clinical implementation of MapRT were also reported. With no buffer margin, MapRT's predictions and experimental collision coordinates showed small average differences but with large standard deviations for gantry (-0.5°±6.2°) and couch (-0.1°±4.8°) collision coordinates. When excluding the kV imaging components, these values were of -0.8°±3.5° for gantry and 0.4°±4.4° for couch. Finally, a 3 cm buffer margin allows for 100% accurate predictions by MapRT of gantry-to-phantom and gantry-to-couch collisions. Among the ∼900 treatment plans checked with MapRT, 22 collisions could be avoided while another 6 plans still incurred a collision but these are mainly due to users' oversights. MapRT easily predict collisions in complex treatment planning. This work demonstrated its reliability using a 3 cm buffer margin. MapRT is a promising tool for increasing security, time saving and workflow improvement.</p>","PeriodicalId":14989,"journal":{"name":"Journal of Applied Clinical Medical Physics","volume":"26 3","pages":""},"PeriodicalIF":2.0,"publicationDate":"2025-02-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/acm2.14572","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143189330","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Dosimetric sensitivity of an enhanced leaf model (ELM) for individual versus averaged machines 单个与平均机器的增强型叶片模型(ELM)的剂量学灵敏度。
IF 2 4区 医学
Journal of Applied Clinical Medical Physics Pub Date : 2025-02-04 DOI: 10.1002/acm2.14621
Rafail Panagi, Rhydian Caines, Carl G. Rowbottom
{"title":"Dosimetric sensitivity of an enhanced leaf model (ELM) for individual versus averaged machines","authors":"Rafail Panagi,&nbsp;Rhydian Caines,&nbsp;Carl G. Rowbottom","doi":"10.1002/acm2.14621","DOIUrl":"10.1002/acm2.14621","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Background</h3>\u0000 \u0000 <p>With the introduction of a new multi-leaf collimator (MLC) enhanced leaf model (ELM) in the Varian Eclipse™ treatment planning system, there is currently limited data regarding the dosimetric sensitivity to real-world variation in the ELM parameters, and its clinical relevance.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Purpose</h3>\u0000 \u0000 <p>To characterize the variation in ELM parameters across a large department with ten linear accelerators and investigate the feasibility of using a single machine-averaged ELM for treatment planning. This could achieve time and resource savings from reduced quality assurance, while allowing easy transfer of patients between machines.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>Clinical plans of a range of sites (head and neck, prostate, breast, lung, and brain), techniques (VMAT, IMRT, SBRT, and SRS), and energies (6 MV, 6 MV FFF, 10 MV, and 10 MV FFF) were recalculated on Varian TrueBeam™ (120 MLC) and Varian EDGE™ (HD120 MLC), with machine-specific ELM beam models, an averaged machine and an outlier machine model. A range of clinically relevant metrics relating to target coverage (e.g. PTV D<sub>98%</sub>, D<sub>50%</sub>, D<sub>2%</sub>) and OAR doses (dosimetric, volumetric, conformity, and gradient indices) were evaluated.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>For the target metrics, the maximum percentage deviation from the mean was 0.422%, 0.157%, and 1.956% for the cases of the individual machines, the averaged machine and the outlier machine correspondingly, while the maximum absolute dose differences were 0.28 Gy, 0.07 Gy, and 0.38 Gy. For the OAR metrics, the maximum deviation from the mean was 1.833%, 0.204%, and 5.722% for the individual, averaged, and outlier machines, while the maximum absolute dose differences were 0.41 Gy, 0.10 Gy, and 0.97 Gy.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>For machines that are well matched in terms of dosimetry for transmission and sweeping gap fields, the use of an averaged machine model is unlikely to introduce clinically significant dosimetric differences to treatment plans.</p>\u0000 </section>\u0000 </div>","PeriodicalId":14989,"journal":{"name":"Journal of Applied Clinical Medical Physics","volume":"26 4","pages":""},"PeriodicalIF":2.0,"publicationDate":"2025-02-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/acm2.14621","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143189345","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
High-precision localization of radiation isocenter using Winston-Lutz test: Impact of collimator angle, phantom position, and field size 使用Winston-Lutz测试进行辐射等中心的高精度定位:准直器角度、幻像位置和视场大小的影响。
IF 2 4区 医学
Journal of Applied Clinical Medical Physics Pub Date : 2025-02-04 DOI: 10.1002/acm2.70000
Weiliang Du
{"title":"High-precision localization of radiation isocenter using Winston-Lutz test: Impact of collimator angle, phantom position, and field size","authors":"Weiliang Du","doi":"10.1002/acm2.70000","DOIUrl":"10.1002/acm2.70000","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Purpose</h3>\u0000 \u0000 <p>This study aimed to evaluate the impact of collimator angle, ball bearing (BB) phantom position, and field size on the accuracy of Winston-Lutz (WL) test–derived radiation isocenters.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>WL tests were performed on four TrueBeam linear accelerators. Fifty-six images (eight gantry angles multiplied by seven collimator angles) were acquired for each WL test. Images with different sets of collimator angles were used to compute the radiation isocenters. The resulting radiation isocenters were correlated with the collimator angles. Then, the BB position and radiation field size were varied for the subsequent WL tests. The calculated BB shifts were compared with the known shifts, and the radiation isocenters were compared between different field sizes.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>The use of a single collimator angle led to errors of as much as 0.4 mm in the calculated radiation isocenters. Systematic differences were observed between the radiation isocenters derived with collimator angle 0° and those derived with 90° and/or 270°. A commonly used opposing collimator angle pair, 90° and 270°, resulted in a vertical 0.1 mm offset of the radiation isocenters toward the ceiling. Oblique opposite or mixed collimator angles yielded radiation isocenter errors less than 0.1 mm. The BB shifts derived from WL tests were less than 0.1 mm from the known shifts. The radiation isocenters varied by less than 0.1 mm between field sizes ranging from 2 × 2 cm<sup>2</sup> to 20 × 20 cm<sup>2</sup>.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>Oblique opposing collimator angle pairs should be considered to minimize errors in localizing radiation isocenters. Uncertainty in BB positioning could be eliminated if the BB is used as a static reference point in space. The field size had no significant effect on the radiation isocenters. With careful design of WL test parameters and image processing, it is possible to achieve a precision of 0.1 mm in localizing radiation isocenters using WL tests.</p>\u0000 </section>\u0000 </div>","PeriodicalId":14989,"journal":{"name":"Journal of Applied Clinical Medical Physics","volume":"26 4","pages":""},"PeriodicalIF":2.0,"publicationDate":"2025-02-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/acm2.70000","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143189353","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A review of accident models and incident analysis techniques 事故模型和事件分析技术综述。
IF 2 4区 医学
Journal of Applied Clinical Medical Physics Pub Date : 2025-02-02 DOI: 10.1002/acm2.14623
Lawrence M. Wong, Todd Pawlicki
{"title":"A review of accident models and incident analysis techniques","authors":"Lawrence M. Wong,&nbsp;Todd Pawlicki","doi":"10.1002/acm2.14623","DOIUrl":"10.1002/acm2.14623","url":null,"abstract":"<p>This review article aims to provide an overview of accident models and incident analysis techniques in the context of radiation oncology. Accident models conceptualize the mechanisms through which accidents occur. Chain-of-event models and systemic models are two main categories of accident models and differ in how accident causation is portrayed. Chain-of-event models focus on the linear sequence of events leading up to an accident, whereas systemic models emphasize the nonlinear relationships between the components in a complex system. The article then introduces various incident analysis techniques, including root cause analysis (RCA), London Protocol, AcciMap, and Causal Analysis Based on Systems Theory (CAST), which are based on these accident models.  The techniques based on the chain-of-event model can be effective in identifying causal factors, safety interventions, and improving safety.  The other techniques based on the systemic models inherently facilitate an examination of how the influence of personal conditions, environmental conditions, and information exchange between different aspects of a system contributed to an accident.  To improve incident analysis, it is essential to translate unsafe human behavior into decision-making flaws and the underlying contextual factors. Where resources allow, it is also crucial to systematically link frontline contributions to organizational and societal aspects of the system and incorporate expertise in safety science and human factors into the analysis team.  The article also touches on related concepts such as Perrow's Normal Accident Theory (NAT), Functional Resonance Analysis Method (FRAM), and Bowtie Analysis, which are not based on specific accident models but have been used for safety improvement in radiation oncology. Overall, different incident analysis techniques have strengths and weaknesses. Taking a systems approach to incident analysis requires a shift from linear thinking to a more nuanced understanding of complex systems. However, the approach also brings unique value and can help improve safety as radiation oncology further gains complexity.</p>","PeriodicalId":14989,"journal":{"name":"Journal of Applied Clinical Medical Physics","volume":"26 3","pages":""},"PeriodicalIF":2.0,"publicationDate":"2025-02-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/acm2.14623","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143080110","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Modeling dosimetric benefits from daily adaptive RT for gynecological cancer patients with and without knowledge-based dose prediction 有或没有基于知识的剂量预测的妇科癌症患者每日适应性放射治疗的剂量学建模益处。
IF 2 4区 医学
Journal of Applied Clinical Medical Physics Pub Date : 2025-01-27 DOI: 10.1002/acm2.14596
Rupesh Ghimire, Lance Moore, Daniela Branco, Dominique L. Rash, Jyoti S. Mayadev, Xenia Ray
{"title":"Modeling dosimetric benefits from daily adaptive RT for gynecological cancer patients with and without knowledge-based dose prediction","authors":"Rupesh Ghimire,&nbsp;Lance Moore,&nbsp;Daniela Branco,&nbsp;Dominique L. Rash,&nbsp;Jyoti S. Mayadev,&nbsp;Xenia Ray","doi":"10.1002/acm2.14596","DOIUrl":"10.1002/acm2.14596","url":null,"abstract":"&lt;div&gt;\u0000 \u0000 \u0000 &lt;section&gt;\u0000 \u0000 &lt;h3&gt; Purpose&lt;/h3&gt;\u0000 \u0000 &lt;p&gt;Daily online adaptive radiotherapy (ART) improves dose metrics for gynecological cancer patients, but the on-treatment process is resource-intensive requiring longer appointments and additional time from the entire adaptive team. To optimize resource allocation, we propose a model to identify high-priority patients.&lt;/p&gt;\u0000 &lt;/section&gt;\u0000 \u0000 &lt;section&gt;\u0000 \u0000 &lt;h3&gt; Methods&lt;/h3&gt;\u0000 \u0000 &lt;p&gt;For 49 retrospective cervical and endometrial cancer patients, we calculated two initial plans: the treated standard-of-care (Initial&lt;sub&gt;SOC&lt;/sub&gt;) and a reduced margin initial plan (Initial&lt;sub&gt;ART&lt;/sub&gt;) for adapting with the Ethos treatment planning system. Daily doses corresponding to standard and reduced margins (Daily&lt;sub&gt;SOC&lt;/sub&gt; and Daily&lt;sub&gt;ART&lt;/sub&gt;) were determined by re-segmenting the anatomy based on the treatment CBCT and calculating dose on a synthetic CT. These initial and daily doses were used to estimate the ART benefit (&lt;span&gt;&lt;/span&gt;&lt;math&gt;\u0000 &lt;semantics&gt;\u0000 &lt;mrow&gt;\u0000 &lt;mi&gt;Δ&lt;/mi&gt;\u0000 &lt;mi&gt;D&lt;/mi&gt;\u0000 &lt;mi&gt;a&lt;/mi&gt;\u0000 &lt;mi&gt;i&lt;/mi&gt;\u0000 &lt;mi&gt;l&lt;/mi&gt;\u0000 &lt;mi&gt;y&lt;/mi&gt;\u0000 &lt;/mrow&gt;\u0000 &lt;annotation&gt;${{Delta}}Daily$&lt;/annotation&gt;\u0000 &lt;/semantics&gt;&lt;/math&gt;= Daily&lt;sub&gt;SOC&lt;/sub&gt;-Daily&lt;sub&gt;ART&lt;/sub&gt;) versus initial plan differences (&lt;span&gt;&lt;/span&gt;&lt;math&gt;\u0000 &lt;semantics&gt;\u0000 &lt;mrow&gt;\u0000 &lt;mi&gt;Δ&lt;/mi&gt;\u0000 &lt;mi&gt;I&lt;/mi&gt;\u0000 &lt;mi&gt;n&lt;/mi&gt;\u0000 &lt;mi&gt;i&lt;/mi&gt;\u0000 &lt;mi&gt;t&lt;/mi&gt;\u0000 &lt;mi&gt;i&lt;/mi&gt;\u0000 &lt;mi&gt;a&lt;/mi&gt;\u0000 &lt;mi&gt;l&lt;/mi&gt;\u0000 &lt;/mrow&gt;\u0000 &lt;annotation&gt;${{Delta}}Initial$&lt;/annotation&gt;\u0000 &lt;/semantics&gt;&lt;/math&gt;= Initial&lt;sub&gt;SOC&lt;/sub&gt;–Initial&lt;sub&gt;ART&lt;/sub&gt;) via multivariate linear regression. Dosimetric benefits were modeled with initial plan differences (&lt;span&gt;&lt;/span&gt;&lt;math&gt;\u0000 &lt;semantics&gt;\u0000 &lt;mrow&gt;\u0000 &lt;mi&gt;Δ&lt;/mi&gt;\u0000 &lt;mi&gt;I&lt;/mi&gt;\u0000 &lt;mi&gt;n&lt;/mi&gt;\u0000 &lt;mi&gt;i&lt;/mi&gt;\u0000 &lt;mi&gt;t&lt;/mi&gt;\u0000 &lt;mi&gt;i&lt;/mi&gt;\u0000 &lt;mi&gt;a&lt;/mi&gt;\u0000 &lt;mi&gt;l&lt;/mi&gt;\u0000 &lt;/mrow&gt;\u0000 &lt;annotation&gt;${{Delta}}Initial$&lt;/annotation&gt;\u0000 &lt;/semantics&gt;&lt;/math&gt;) of &lt;span&gt;&lt;/span&gt;&lt;math&gt;\u0000 &lt;semantics&gt;\u0000 &lt;mrow&gt;\u0000 &lt;mi&gt;","PeriodicalId":14989,"journal":{"name":"Journal of Applied Clinical Medical Physics","volume":"26 3","pages":""},"PeriodicalIF":2.0,"publicationDate":"2025-01-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/acm2.14596","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143046827","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Evaluation of AI-based auto-contouring tools in radiotherapy: A single-institution study 放疗中基于人工智能的自动轮廓工具的评估:一项单机构研究。
IF 2 4区 医学
Journal of Applied Clinical Medical Physics Pub Date : 2025-01-21 DOI: 10.1002/acm2.14620
Tingyu Wang, James Tam, Thomas Chum, Cyril Tai, Deborah C. Marshall, Michael Buckstein, Jerry Liu, Sheryl Green, Robert D. Stewart, Tian Liu, Ming Chao
{"title":"Evaluation of AI-based auto-contouring tools in radiotherapy: A single-institution study","authors":"Tingyu Wang,&nbsp;James Tam,&nbsp;Thomas Chum,&nbsp;Cyril Tai,&nbsp;Deborah C. Marshall,&nbsp;Michael Buckstein,&nbsp;Jerry Liu,&nbsp;Sheryl Green,&nbsp;Robert D. Stewart,&nbsp;Tian Liu,&nbsp;Ming Chao","doi":"10.1002/acm2.14620","DOIUrl":"10.1002/acm2.14620","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Background</h3>\u0000 \u0000 <p>Accurate delineation of organs at risk (OARs) is crucial yet time-consuming in the radiotherapy treatment planning workflow. Modern artificial intelligence (AI) technologies had made automation of OAR contouring feasible. This report details a single institution's experience in evaluating two commercial auto-contouring software tools and making well-informed decisions about their clinical adoption.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>A cohort of 36 patients previously treated at our institution were selected for the software performance assessment. Fifty-eight OAR structures from seven disease sites were automatically segmented with each tool. Five radiation oncologists with different specialties qualitatively scored the automatic OAR contours’ clinical usability by a 4-level scale (0–3), termed as quality score (QS), representing from “0: not usable” to “3: directly usable for a clinic.” Additionally, quantitative comparison with clinically approved contours using Dice similarity coefficient (DSC) and the 95% Hausdorff distance (HD95) was performed in complement to QS from physicians.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Result</h3>\u0000 \u0000 <p>Software A achieved an average QS of 2.17 ± 0.69, comparable to Software B's average QS of 2.17 ± 0.72. Software B performed better with more OARs (42 vs. 37) that required minor or no modification than Software A. Major modifications were needed for 13 out of 58 automated contours from both tools. Both DSC and HD95 scores for the two tools were comparable to each other, with DSC: 0.67 ± 0.23 versus 0.66 ± 0.21 and HD95: 13.07 ± 15.84 versus 15.55 ± 18.45 for Software A and Software B, respectively. Correlation coefficients between the physician score and the quantitative metrics suggested that the contouring results from Software A aligned more closely with the physician's evaluations.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>Based on our study, either software tool could produce clinically acceptable contours for about 65% of the OAR structures. However, further refinement is necessary for several challenging OARs to improve model performance.</p>\u0000 </section>\u0000 </div>","PeriodicalId":14989,"journal":{"name":"Journal of Applied Clinical Medical Physics","volume":"26 4","pages":""},"PeriodicalIF":2.0,"publicationDate":"2025-01-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/acm2.14620","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143005942","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Online correction of intrafraction motion during volumetric modulated arc therapy for prostate radiotherapy using fiducial-based kV imaging: A cohort study quantifying the frequency of shifts and analysis of men at highest risk 使用基于基准的kV成像在线校正前列腺放射治疗中体积调制电弧治疗期间的屈光内运动:一项量化偏移频率和高危男性分析的队列研究。
IF 2 4区 医学
Journal of Applied Clinical Medical Physics Pub Date : 2025-01-17 DOI: 10.1002/acm2.14603
Lucas M. Serra, Tianming Wu, Mark C. Korpics, Kamil Yenice, Stanley L. Liauw
{"title":"Online correction of intrafraction motion during volumetric modulated arc therapy for prostate radiotherapy using fiducial-based kV imaging: A cohort study quantifying the frequency of shifts and analysis of men at highest risk","authors":"Lucas M. Serra,&nbsp;Tianming Wu,&nbsp;Mark C. Korpics,&nbsp;Kamil Yenice,&nbsp;Stanley L. Liauw","doi":"10.1002/acm2.14603","DOIUrl":"10.1002/acm2.14603","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Background</h3>\u0000 \u0000 <p>Various methods exist to correct for intrafraction motion (IFM) of the prostate during radiotherapy. We sought to characterize setup corrections in our practice informed by the TrueBeam Advanced imaging package, and analyze factors associated with IFM.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>132 men received radiation therapy for prostate cancer with a volumetric modulated arc therapy technique. All patients underwent planning CT immediately following transrectal placement of 3 fiducial markers. The most common RT course was 20 fractions (range: 17–44). Triggered kV images were acquired every 15 seconds over 2–3 full arcs using an onboard imaging system. IFM correction was considered when if any two fiducial markers in a single kV image were observed to be outside beyond a 3 mm tolerance margin. A manual 2D/3D match was performed using the fiducial markers from the single triggered kV image to obtain a suggested couch shift. Shift data for three (x, y, z) planes were extracted from the record and verify system and expressed as a single 3-dimensional translation. Shift percent (SP) was defined as the number of instances of an intrafraction correction divided by the total number of fractions for a given patient.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Over 2659 fractions of radiation, IFM was observed and corrected for 582 times across 463 (17%) fractions, and at least one shift was made over the course of treatment in 77% of men. Univariate analysis revealed that larger rectal volume or width, smaller prostate volume, and use of ADT were associated with SP &gt; 20% (p &lt; 0.05). Men with a rectal width &gt;3.6 cm were more likely to have IFM corrected (SP &gt; 20% 47% vs 18%, p = 0.0016). On multivariate analysis, only rectal volume and width were associated with IFM.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>In this cohort study, 17% of fractions were interrupted to apply at least one couch shift. Men treated with shorter courses of therapy, such as stereotactic body radiation therapy, or men at high risk for IFM (e.g. larger rectal size) may warrant more careful consideration regarding the implications of IFM.</p>\u0000 </section>\u0000 </div>","PeriodicalId":14989,"journal":{"name":"Journal of Applied Clinical Medical Physics","volume":"26 4","pages":""},"PeriodicalIF":2.0,"publicationDate":"2025-01-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/acm2.14603","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143005947","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Automatic image quality evaluation in digital radiography using a modified version of the IAEA radiography phantom allowing multiple detection tasks 使用允许多个检测任务的原子能机构放射照相虚影的改进版本的数字放射照相中的自动图像质量评估:一个多检测任务原子能机构放射照相虚影。
IF 2 4区 医学
Journal of Applied Clinical Medical Physics Pub Date : 2025-01-13 DOI: 10.1002/acm2.14599
Ioannis A. Tsalafoutas, Shady AlKhazzam, Virginia Tsapaki, Mohammed Hassan Kharita
{"title":"Automatic image quality evaluation in digital radiography using a modified version of the IAEA radiography phantom allowing multiple detection tasks","authors":"Ioannis A. Tsalafoutas,&nbsp;Shady AlKhazzam,&nbsp;Virginia Tsapaki,&nbsp;Mohammed Hassan Kharita","doi":"10.1002/acm2.14599","DOIUrl":"10.1002/acm2.14599","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Purpose</h3>\u0000 \u0000 <p>To evaluate image quality (IQ) of for-processing (raw) and for-presentation (clinical) radiography images, under different exposure conditions and digital image post-processing algorithms, using a phantom that enables multiple detection tasks.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>A modified version of the radiography phantom described in the IAEA Human Health Series No. 39 publication was constructed, incorporating six additional Aluminum (Al) targets of thicknesses both smaller and larger than the standard one. Raw and clinical images were simultaneously acquired using two digital radiography units from different manufacturers, various exposure parameters and different examination protocols. The phantom images were read using the free IAEA software (ATIA) that estimates automatically various IQ-metrics in images of the original phantom. Since in the modified phantom had seven Al targets, images were read seven times, one for each different Al thickness. The IQ-metrics’ values obtained were analyzed to investigate their dependence on incident air kerma on the image receptor, tube potential, examination protocol, image type (raw or clinical), Al-target thicknesses, and manufacturer.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>The IQ-metric values calculated using the modified IAEA phantom images can be radically different between raw and clinical images, and between different manufacturers, irrespectively whether only the standard or all the different Al-target thicknesses are considered. The modulation transfer function (MTF) and the signal-to-noise-ratio (SNR) dependence on exposure conditions and post-processing algorithms do not always follow the same trends for raw and clinical images and/or different manufacturers, while the signal-difference-to-noise-ratio (SDNR) and the detectability index (d′), despite their differences, seem more appropriate to characterize IQ. However, the d′ metric, which also considers both MTF and the normalized noise power spectrum (NNPS) should be considered more complete IQ-metric than SDNR.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>Though theoretically d′ values should be calculated using raw images, clinical images can be also used, at least for constancy tests.</p>\u0000 </section>\u0000 </div>","PeriodicalId":14989,"journal":{"name":"Journal of Applied Clinical Medical Physics","volume":"26 2","pages":""},"PeriodicalIF":2.0,"publicationDate":"2025-01-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/acm2.14599","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142978448","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
New gantry angle-dependent beam control optimization with Elekta linear accelerator for VMAT delivery 基于Elekta直线加速器的新型龙门角度相关光束控制优化。
IF 2 4区 医学
Journal of Applied Clinical Medical Physics Pub Date : 2025-01-08 DOI: 10.1002/acm2.14598
Adriaan Abraham van Appeldoorn, Johannes Gerardus Maria Kok, Jochem Willem Heiko Wolthaus
{"title":"New gantry angle-dependent beam control optimization with Elekta linear accelerator for VMAT delivery","authors":"Adriaan Abraham van Appeldoorn,&nbsp;Johannes Gerardus Maria Kok,&nbsp;Jochem Willem Heiko Wolthaus","doi":"10.1002/acm2.14598","DOIUrl":"10.1002/acm2.14598","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Introduction</h3>\u0000 \u0000 <p>This paper describes a method to improve gantry-dependent beam steering for Elekta traveling wave linear accelerators by applying the measured and filtered beam servo corrections to the existing lookup table (LUT). Beam steering has a direct influence on the treatment accuracy by affecting the beam symmetry and position. The presented method provides an improved LUT with respect to the default Elekta method to reduce treatment delivery interruptions. These interruptions are known to contribute to unwanted intrafraction motion and longer treatment times.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>Compared to the default method of the manufacturer, this new method takes both clockwise and counterclockwise rotation to compensate for magnetic hysteresis as well as previous configuration and noise filtering into account. The improved method to determine the lookup table uses service graphing information from the linac without the need for additional symmetry information. The clinical configuration of the flattened beam energies remains untouched during the data record.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>This method results in a configuration where the gantry-dependent steering is optimized over the full arc with optimal balance in the hysteresis and minimizing the effect of errors in the steering values. This method is a less error-prone process compared to the methodology described in previous research, still achieving a reduction of interruption of about 60 percent compared to the Elekta method.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>This study shows a simplified way to optimize linac stability with improved LUT. The optimized LUT results in a lower number of interruptions, preventing downtime, and a lower risk of intrafraction motion due to longer treatment time.</p>\u0000 </section>\u0000 </div>","PeriodicalId":14989,"journal":{"name":"Journal of Applied Clinical Medical Physics","volume":"26 3","pages":""},"PeriodicalIF":2.0,"publicationDate":"2025-01-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/acm2.14598","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142949301","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Determination of the beam quality correction factor k Q msr ${k}_{{Q}_{{mathrm{msr}}}}$ for the PTW Semiflex 3D ionization chamber for the reference dosimetry at ZAP-X PTW Semiflex三维电离室参考剂量测定的光束质量校正因子k Q msr ${k}_{{Q}_{{ maththrm {msr}}}}$
IF 2 4区 医学
Journal of Applied Clinical Medical Physics Pub Date : 2025-01-07 DOI: 10.1002/acm2.14610
Katrin Saße, Karina Albers, Daniela Eulenstein, Georg Weidlich, Björn Poppe, Hui Khee Looe
{"title":"Determination of the beam quality correction factor \u0000 \u0000 \u0000 k\u0000 \u0000 Q\u0000 msr\u0000 \u0000 \u0000 ${k}_{{Q}_{{mathrm{msr}}}}$\u0000 for the PTW Semiflex 3D ionization chamber for the reference dosimetry at ZAP-X","authors":"Katrin Saße,&nbsp;Karina Albers,&nbsp;Daniela Eulenstein,&nbsp;Georg Weidlich,&nbsp;Björn Poppe,&nbsp;Hui Khee Looe","doi":"10.1002/acm2.14610","DOIUrl":"10.1002/acm2.14610","url":null,"abstract":"&lt;div&gt;\u0000 \u0000 \u0000 &lt;section&gt;\u0000 \u0000 &lt;h3&gt; Purpose&lt;/h3&gt;\u0000 \u0000 &lt;p&gt;The self-shielding radiosurgery system ZAP-X consists of a 3 MV linear accelerator and eight round collimators. For this system, it is a common practice to perform the reference dosimetry using the largest 25 mm diameter collimator at a source-to-axis distance (SAD) of 45 cm with the PTW Semiflex3D chamber placed at a measurement depth of 7 mm in water. Existing dosimetry protocols do not provide correction for these measurement conditions. Therefore, Monte Carlo simulations were performed to quantify the associated beam quality correction factor &lt;span&gt;&lt;/span&gt;&lt;math&gt;\u0000 &lt;semantics&gt;\u0000 &lt;msubsup&gt;\u0000 &lt;mi&gt;k&lt;/mi&gt;\u0000 &lt;mrow&gt;\u0000 &lt;msub&gt;\u0000 &lt;mi&gt;Q&lt;/mi&gt;\u0000 &lt;mi&gt;msr&lt;/mi&gt;\u0000 &lt;/msub&gt;\u0000 &lt;mo&gt;,&lt;/mo&gt;\u0000 &lt;msub&gt;\u0000 &lt;mi&gt;Q&lt;/mi&gt;\u0000 &lt;mi&gt;ref&lt;/mi&gt;\u0000 &lt;/msub&gt;\u0000 &lt;/mrow&gt;\u0000 &lt;mrow&gt;\u0000 &lt;msub&gt;\u0000 &lt;mi&gt;f&lt;/mi&gt;\u0000 &lt;mi&gt;msr&lt;/mi&gt;\u0000 &lt;/msub&gt;\u0000 &lt;mo&gt;,&lt;/mo&gt;\u0000 &lt;msub&gt;\u0000 &lt;mi&gt;f&lt;/mi&gt;\u0000 &lt;mi&gt;ref&lt;/mi&gt;\u0000 &lt;/msub&gt;\u0000 &lt;/mrow&gt;\u0000 &lt;/msubsup&gt;\u0000 &lt;annotation&gt;$k_{{Q}_{{mathrm{msr}}},{Q}_{{mathrm{ref}}}}^{{f}_{{mathrm{msr}}},{f}_{{mathrm{ref}}}}$&lt;/annotation&gt;\u0000 &lt;/semantics&gt;&lt;/math&gt;.&lt;/p&gt;\u0000 &lt;/section&gt;\u0000 \u0000 &lt;section&gt;\u0000 \u0000 &lt;h3&gt; Methods&lt;/h3&gt;\u0000 \u0000 &lt;p&gt;The &lt;span&gt;&lt;/span&gt;&lt;math&gt;\u0000 &lt;semantics&gt;\u0000 &lt;msubsup&gt;\u0000 &lt;mi&gt;k&lt;/mi&gt;\u0000 &lt;mrow&gt;\u0000 &lt;msub&gt;\u0000 &lt;mi&gt;Q&lt;/mi&gt;\u0000 &lt;mi&gt;msr&lt;/mi&gt;\u0000 &lt;/msub&gt;\u0000 &lt;mo&gt;,&lt;/mo&gt;\u0000 &lt;msub&gt;\u0000 &lt;mi&gt;Q&lt;/mi&gt;\u0000 &lt;mi&gt;ref&lt;/mi&gt;\u0000 &lt;/msub&gt;\u0000 &lt;/mrow&gt;\u0000 &lt;mrow&gt;\u0000 &lt;msub&gt;\u0000 &lt;mi&gt;f&lt;/mi&gt;\u0000 &lt;mi&gt;msr&lt;/mi&gt;\u0000 &lt;/msub&gt;\u0000 &lt;mo&gt;,&lt;/mo&gt;\u0000 &lt;msub&gt;\u0000 &lt;mi&gt;f&lt;/mi&gt;\u0000 &lt;mi&gt;ref&lt;/mi&gt;\u0000 ","PeriodicalId":14989,"journal":{"name":"Journal of Applied Clinical Medical Physics","volume":"26 2","pages":""},"PeriodicalIF":2.0,"publicationDate":"2025-01-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/acm2.14610","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142949299","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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