Journal of affective disorders最新文献

{"title":"Disparities in group-based medical mistrust and associations with mental health symptoms during the COVID-19 pandemic","authors":"Jeremy W. Luk ,&nbsp;LaToya Sewell ,&nbsp;Bethany L. Stangl ,&nbsp;Courtney L. Vaughan ,&nbsp;Andrew J. Waters ,&nbsp;Melanie L. Schwandt ,&nbsp;David Goldman ,&nbsp;Vijay A. Ramchandani ,&nbsp;Nancy Diazgranados","doi":"10.1016/j.jad.2025.01.137","DOIUrl":"10.1016/j.jad.2025.01.137","url":null,"abstract":"<div><h3>Background</h3><div>Racial/ethnic disparities in health-related outcomes may have been exacerbated during the COVID-19 pandemic. Individuals from racial/ethnic minority groups or with a history of alcohol use disorder (AUD) may have greater medical mistrust. We examined racial/ethnic and AUD-related differences in group-based medical mistrust during the pandemic and tested whether medical mistrust dimensions were associated with mental health symptoms.</div></div><div><h3>Methods</h3><div>Two hundred and fifty participants from the National Institute on Alcohol Abuse and Alcoholism COVID-19 Pandemic Impact on Alcohol Study completed an online survey between April and July of 2022. Exploratory factor analysis and path analysis were conducted.</div></div><div><h3>Results</h3><div>Group-based medical mistrust scores were elevated among participants who identified as Non-Hispanic Black and those with a history of AUD. Two medical mistrust dimensions were found: (1) Suspicion and Lack of Provider Support, and (2) Group Disparities in Health Care. Compared to Non-Hispanic White participants, Non-Hispanic Black participants reported higher scores on the Suspicion and Lack of Provider Support dimension of medical mistrust, which was associated with higher mental health symptoms. This medical mistrust dimension was also a significant mediator of the observed group differences in mental health symptoms.</div></div><div><h3>Limitations</h3><div>Cross-sectional data, aggregation of racial/ethnic groups with small sample sizes, and nonrepresentative sample.</div></div><div><h3>Conclusions</h3><div>Non-Hispanic Black individuals and individuals with AUD may be more vulnerable to mental health symptoms due to higher suspicion toward medical professionals and healthcare systems and perceived lack of support from healthcare providers. Increased awareness among healthcare providers may help address medical mistrust, encourage help-seeking behaviors, and alleviate mental health symptoms.</div></div>","PeriodicalId":14963,"journal":{"name":"Journal of affective disorders","volume":"375 ","pages":"Pages 517-524"},"PeriodicalIF":4.9,"publicationDate":"2025-01-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143074663","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Associations between perceived built environment and depressive symptoms in China: The mediating roles of neighborly relationships and community attachment across age-gender groups","authors":"Yizhou Pan ,&nbsp;Wanting Ren ,&nbsp;Zurong Liang","doi":"10.1016/j.jad.2025.01.130","DOIUrl":"10.1016/j.jad.2025.01.130","url":null,"abstract":"<div><h3>Background</h3><div>While prior research has linked the built environment to mental health, little attention has been given to how this relationship and its mechanisms differ at the intersection of gender and age. This study examines the direct and indirect associations between the perceived built environment and depressive symptoms, with neighborly relationships and community attachment as mediators. It also investigates how these associations vary across age-gender groups.</div></div><div><h3>Methods</h3><div>Drawing from nationally representative data from two waves of the China Family Panel Studies (<em>n</em> = 14,200), this study applied a moderated mediation model to analyze the mediating role of neighborly relationships and community attachment, as well as the moderating role of age-gender groups.</div></div><div><h3>Results</h3><div>The perceived built environment was negatively associated with depressive symptoms, and this relationship was mediated by both neighborly relationships and community attachment. Age-gender groups moderated both the direct and indirect associations, with middle-aged males exhibiting the strongest direct association, while middle-aged females demonstrated more pronounced indirect associations through social cohesion.</div></div><div><h3>Limitations</h3><div>This study relied on self-reported data to assess the built environment, and both neighborly relationships and community attachment were measured using single-item indicators, which may limit the depth of analysis. Furthermore, the observational design of the study precludes definitive causal inferences from the findings.</div></div><div><h3>Conclusions</h3><div>The study reveals varying associations between the perceived built environment and depressive symptoms across age-gender groups, with middle-aged males more affected by environmental stressors and middle-aged females benefiting from social cohesion. These findings provide insights for targeted interventions and policies.</div></div>","PeriodicalId":14963,"journal":{"name":"Journal of affective disorders","volume":"375 ","pages":"Pages 437-447"},"PeriodicalIF":4.9,"publicationDate":"2025-01-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143074558","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comorbid anxiety in depression and rTMS treatment response: A retrospective study","authors":"Reza Kazemi ,&nbsp;Reza Rostami ,&nbsp;Mehdi Rezaei ,&nbsp;Sepideh Hedayati ,&nbsp;Sanaz Khomami ,&nbsp;Abed L. Hadipour","doi":"10.1016/j.jad.2025.01.148","DOIUrl":"10.1016/j.jad.2025.01.148","url":null,"abstract":"<div><h3>Introduction</h3><div>Few studies have examined the relationship between anxiety and response to repetitive transcranial magnetic stimulation (rTMS) in patients with unipolar depressive disorder (UDD) and bipolar depressive disorder (BDD). The primary aim of this study was to investigate the correlation between anxiety symptoms and the response to rTMS in individuals with comorbid anxiety, in both UDD and BDD patients. The secondary aim was to evaluate the efficacy of rTMS in reducing depressive symptoms, anxiety, and different subtypes of anxiety disorder.</div></div><div><h3>Methods</h3><div>A total of 379 outpatients (214 UDD, 165 BDD) underwent 20 sessions of either right unilateral low-frequency rTMS or sequential bilateral rTMS targeting the dorsolateral prefrontal cortex (DLPFC). Beck Anxiety Inventory (BAI) and Beck Depression Inventory (BDI-II) were used for assessment.</div></div><div><h3>Results</h3><div>Binary logistic regression analysis indicated that pre-treatment physical anxiety scores showed a negative correlation with rTMS response, while subjective anxiety scores were positively associated. Distinct and overlapping response profiles for UDD and BDD patients with comorbid anxiety were identified based on anxiety symptoms. Predictive values for the BDD group were more reliable than those for the UDD group (PPV: 75 %, NPV: 77 %). Moreover, both unilateral and bilateral rTMS significantly reduced depressive symptoms as well as physical, subjective, and panic-related anxiety symptoms.</div></div><div><h3>Conclusion</h3><div>The findings suggest that in both UDD and BDD, physical anxiety symptoms are linked to less response to rTMS, whereas subjective anxiety symptoms are associated with more response. Future prospective studies are required to confirm the predictive value of anxiety symptoms in UDD and BDD patients who suffer from comorbid anxiety.</div></div>","PeriodicalId":14963,"journal":{"name":"Journal of affective disorders","volume":"376 ","pages":"Pages 36-46"},"PeriodicalIF":4.9,"publicationDate":"2025-01-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143074622","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Shorter weeknight sleep duration mediates the relationship between earlier adrenarche and depressed mood in adolescents","authors":"Ekaterina Sadikova ,&nbsp;Emily Oken ,&nbsp;Sheryl L. Rifas-Shiman ,&nbsp;Elise Robinson ,&nbsp;Izzuddin M. Aris ,&nbsp;Henning Tiemeier","doi":"10.1016/j.jad.2025.01.142","DOIUrl":"10.1016/j.jad.2025.01.142","url":null,"abstract":"<div><h3>Background</h3><div>Shorter weeknight sleep duration has not been assessed as a mediating mechanism linking earlier pubertal timing to a greater burden of adolescent depression symptoms.</div></div><div><h3>Methods</h3><div>Among 1138 participants (48.6 % female) from Project Viva, a pre-birth longitudinal cohort, we examined relationships among pubertal timing measures, actigraphy-captured and self-reported weeknight sleep duration across mid-adolescence, and depression symptoms in late adolescence. We assessed pubertal timing using age at peak height velocity, self-reported adrenarche (Tanner pubic hair stage) and parent-reported Pubertal Development Scale scores in early adolescence. Relationships were adjusted for age, sex, mid-childhood BMI, and socioeconomic status; effect modification by sex was considered throughout. The mediational g-formula estimated the indirect effect of pubertal timing on depression symptoms via weeknight sleep duration.</div></div><div><h3>Results</h3><div>All measures of earlier pubertal timing predicted shorter actigraphy-measured sleep duration; self-reported adrenarche predicted self-reported sleep duration and depression symptoms. No effect modification by sex was found. In both sexes, a 1-stage advance in adrenarche was associated with less (−0.14 h (95 % CI -0.23,-0.05)) self-reported sleep on weeknights across the mid-adolescent years. The relationship between earlier adrenarche and depression symptoms was mediated by self-reported weeknight sleep duration – a decrease in sleep duration in mid-adolescent years attributable to a 1-stage advance in adrenarche increased depression symptoms by 0.22 points (95 % CI 0.08,0.40).</div></div><div><h3>Limitations</h3><div>The geographic specificity and attrition in Project Viva limit the generalizability of our findings.</div></div><div><h3>Conclusions</h3><div>Maintaining adequate weeknight sleep across adolescent years may mitigate the impact of earlier adrenarche on depressed mood in late adolescence.</div></div>","PeriodicalId":14963,"journal":{"name":"Journal of affective disorders","volume":"376 ","pages":"Pages 52-58"},"PeriodicalIF":4.9,"publicationDate":"2025-01-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143065689","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Age-related eye diseases and subsequent risk of mental disorders in older adults: A real-world multicenter study","authors":"Gyubeom Hwang ,&nbsp;So Hee Lee ,&nbsp;Dong Yun Lee ,&nbsp;ChulHyoung Park ,&nbsp;Hyun Woong Roh ,&nbsp;Sang Joon Son ,&nbsp;Rae Woong Park","doi":"10.1016/j.jad.2025.01.128","DOIUrl":"10.1016/j.jad.2025.01.128","url":null,"abstract":"<div><h3>Background</h3><div>The relationship between age-related eye diseases and the subsequent risk of dementia and depressive disorders remains inconsistent. Furthermore, the effects on anxiety disorders and sleep disorders have been underexplored. This study aims to comprehensively examine the impact of age-related eye diseases on common mental disorders in older adults, thereby enhancing our understanding of the mental health implications in these conditions.</div></div><div><h3>Methods</h3><div>The electronic health records of 1,522,036 patients aged over 60 from ten institutions in South Korea were analyzed. Patients with and without age-related eye diseases were identified, and 1:4 propensity score matching (PSM) was implemented. A 10-year longitudinal analysis was conducted using the Cox proportional hazards model to calculate the hazard ratios (HR). A meta-analysis was performed to combine the results from different institutions. Subgroup analyses were conducted to explore the impact of specific age-related eye diseases (cataract, glaucoma, age-related macular degeneration) on mental disorders.</div></div><div><h3>Results</h3><div>A total of 41,637 patients with age-related eye disease were matched with 134,908 patients without such conditions. Patients with age-related eye disease showed a significantly higher risk of mental disorders (dementia, HR: 1.21 [95 % CI: 1.14–1.27]; depressive disorders, HR: 1.28 [95 % CI: 1.20–1.36]; anxiety disorders, HR: 1.31 [95 % CI: 1.22–1.41]; sleep disorders, HR: 1.29 [95 % CI: 1.22–1.37]). In subgroup analyses, each of the three age-related eye diseases was significantly associated with an increased risk of mental disorders. (cataract, HR: 1.25–1.33; glaucoma, HR: 1.15–1.49; age-related macular degeneration, HR: 1.18–1.37).</div></div><div><h3>Conclusion</h3><div>Age-related eye diseases increase the risk of developing mental disorders in older adults, highlighting the need for a multidisciplinary approach to patient care in these conditions.</div></div>","PeriodicalId":14963,"journal":{"name":"Journal of affective disorders","volume":"375 ","pages":"Pages 306-315"},"PeriodicalIF":4.9,"publicationDate":"2025-01-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143065506","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Plasma biomarkers of endothelial function in people with depressive disorder: A systematic review and meta-analysis","authors":"Aline Josiane Waclawovsky ,&nbsp;Eduarda Bitencourt dos Santos ,&nbsp;Antônio Anderson Ramos de Oliveira ,&nbsp;Brendon Stubbs ,&nbsp;Felipe Barreto Schuch","doi":"10.1016/j.jad.2025.01.138","DOIUrl":"10.1016/j.jad.2025.01.138","url":null,"abstract":"<div><div>The objective of this study is to conduct a literature review and summarize existing research comparing levels of blood markers of endothelial function in people with depression with controls. We searched major databases (Embase, PubMed, Web of Science, and PsycINFO) from inception to 23.07.2023, for studies comparing endothelial function blood markers in people with depression and controls including intercellular adhesion molecule-1 (sICAM-1), vascular cell adhesion molecule-1 (sVCAM-1), monocyte chemoattractant protein-1 (MCP-1), and sE-selectin. Comparative random effects meta-analysis, calculating standardized mean differences in levels of sICAM-1, sVCAM-1, MCP-1, and sE-selectin between depressed and controls were conducted. Study protocol was registered with PROSPERO (CRD42020222487). Nineteen studies including 10,566 participants [1322 depressed (mean age = 49.1 years, 63 % females) and 9239 controls (mean age = 52.3 years, 57.5 % females)] were included. People with depression had higher levels of sICAM-1 (SMD = 0.98, 95 % CI: 0.52; 1.44, <em>P</em> &lt; 0.001) and MCP-1 (SMD = 0.37, 95 % CI: 0.01; 0.72, <em>P</em> = 0.04) than controls. There was a small difference on sVCAM-1 (k = 10, SMD = 0.215, 95%CI: 0.013; 0.417, <em>p</em> = 0.04), but no difference in levels of E-selectin between people with depression and controls (k = 5,SMD = 0.21, 95%CI:-0.09;0.52, <em>P</em> = 0.17). Subgroup analyzes demonstrated that people with depression and comorbid chronic illnesses, such as diabetes, have higher levels of sICAM-1 than people with depression without comorbid chronic illness. Mean age moderate the difference in sICAM-1 levels between depressed and controls (SMD = 0.01, 95%CI:-0.05;-0.02,<em>P</em> &lt; 0.001, R² = 0.61). Our findings suggest that people with depression exhibit increased levels of endothelial activation markers compared to controls, suggesting an endothelial dysfunction among this population.</div></div>","PeriodicalId":14963,"journal":{"name":"Journal of affective disorders","volume":"375 ","pages":"Pages 297-305"},"PeriodicalIF":4.9,"publicationDate":"2025-01-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143065683","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cognitive hierarchy in mood disorders and relations to daily functioning","authors":"Johanna Mariegaard Schandorff ,&nbsp;Viktoria Damgaard ,&nbsp;Bethany Little ,&nbsp;Hanne Lie Kjærstad ,&nbsp;Jeff Zarp ,&nbsp;Anne Juul Bjertrup ,&nbsp;Lars Vedel Kessing ,&nbsp;Ulla Knorr ,&nbsp;Maj Vinberg ,&nbsp;Peter Gallagher ,&nbsp;Kamilla Woznica Miskowiak","doi":"10.1016/j.jad.2025.01.143","DOIUrl":"10.1016/j.jad.2025.01.143","url":null,"abstract":"<div><div>Cognitive impairment affects approximately 50 % of patients with mood disorders during remission, which correlates with poorer daily-life functioning. The hierarchical organisation of cognitive processes may mean that some cognitive deficits, e.g., memory impairments, are secondary to impairments in suggested core processes, including executive functions, working memory, attention, and psychomotor speed. The exact structure of a cognitive hierarchy in mood disorders is unclear. In this study, we aimed to examine relationships between cognitive domains using network graphs. Further, we aimed to explore whether impairments in the proposed ‘core cognitive domains’ mediated patients' verbal memory impairment and functional disability using mediation and hierarchical regression analyses. We pooled data from patients with mood disorders and healthy controls (HC) from 10 original studies. In total, 1505 participants were included in the analyses (<em>n</em> = 900 patients; <em>n</em> = 605 HC). We found that cognitive domains were more intercorrelated in patients than in HC. Executive functions, working memory, and attention and psychomotor speed almost fully accounted for illness-associated verbal learning and memory impairments, indicating partial mediation. Of the core domains, working memory explained the largest amount of variance in memory impairments and functional disability. Our findings highlight the importance of targeting core cognitive domains in pro-cognitive interventions.</div></div>","PeriodicalId":14963,"journal":{"name":"Journal of affective disorders","volume":"375 ","pages":"Pages 239-248"},"PeriodicalIF":4.9,"publicationDate":"2025-01-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143065575","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prevalence and network structure of depression, anxiety and adverse doctor-patient relationship risks among patients with physical diseases: A cross-sectional study","authors":"Jianqiang Wang ,&nbsp;Yuru Du ,&nbsp;Yuhan Peng ,&nbsp;Yishan Deng ,&nbsp;Yiran Ge ,&nbsp;Zheng Liu ,&nbsp;Jing Lv ,&nbsp;Gengdan Hu ,&nbsp;Zengren Zhao ,&nbsp;Youdong Li","doi":"10.1016/j.jad.2025.01.144","DOIUrl":"10.1016/j.jad.2025.01.144","url":null,"abstract":"<div><h3>Background</h3><div>Mental health issues among patients with physical diseases are increasingly common. This study investigated the prevalence of depression, anxiety, and adverse doctor-patient relationship risks (ADRR) among patients with physical diseases, and the central and bridge symptoms of this network structure.</div></div><div><h3>Methods</h3><div>A total of 14,344 patients with physical diseases enrolled in this survey. The Patient Health Questionnaire-9 (PHQ-9), Generalized Anxiety Disorder-7 (GAD-7), and Psychological Safety Questionnaire were used to evaluate anxiety, depression, and ADRR. The “qgraph” package in R 4.4.3 was used to construct a network model to identify central and bridge symptoms.</div></div><div><h3>Results</h3><div>The prevalence rates of depression, anxiety, and ADRR were found to be 9.52 % (95 % confidence interval (CI): 9.04–10.00 %), 19.35 % (95 % CI: 18.71–20.00 %), and 4.29 % (95 % CI: 3.96–4.62 %), respectively. Within the network structure, the central symptoms identified were ‘Sad mood,’ ‘Restlessness,’ and ‘Excessive worry,’ which also served as the bridge symptoms. The flow network analysis revealed that ADRR exhibited the strongest associations with ‘Anhedonia’, ‘Restlessness’, and ‘Suicidal ideation’. Additionally, ‘Suicidal ideation’ shows strongest correlations with ‘Guilt’, ‘Concentration’, and ‘Restlessness’.</div></div><div><h3>Limitation</h3><div>The generalizability of the study's findings is constrained, as the sample consisted exclusively of inpatients, potentially limiting applicability to non-hospitalized individuals with physical illnesses.</div></div><div><h3>Conclusion</h3><div>This study provides novel insights into the comorbidity of depression, anxiety, and ADRR at the symptom level in patients with physical diseases through the application of network analysis. The identification of bridge symptoms highlights potential targets for interventions aimed at addressing the comorbidity among these disorders.</div></div>","PeriodicalId":14963,"journal":{"name":"Journal of affective disorders","volume":"376 ","pages":"Pages 122-130"},"PeriodicalIF":4.9,"publicationDate":"2025-01-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143065688","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Factor structure and measurement invariance of the GAD-7 across time, sex, and language in young adults","authors":"Teodora Riglea ,&nbsp;Robert J. Wellman ,&nbsp;Marie-Pierre Sylvestre ,&nbsp;Catherine Sabiston ,&nbsp;Jennifer O'Loughlin","doi":"10.1016/j.jad.2025.01.117","DOIUrl":"10.1016/j.jad.2025.01.117","url":null,"abstract":"<div><h3>Introduction</h3><div>The Generalized Anxiety Disorder-7 Scale (GAD-7) is widely used to measure anxiety symptom severity. One-factor, two-factor, and bifactor latent structures are supported by previous research. Yet, measurement invariance of the GAD-7 across sex and language (i.e., between groups) and longitudinally (i.e., within group over time) is infrequently studied in population-based samples. The objective was to examine the factor structure of the GAD-7 and its measurement invariance across sex, language, and time in young adults.</div></div><div><h3>Methods</h3><div>Data were drawn from an ongoing longitudinal investigation in Canada that began in 1999–2000 at age 12. One-factor, two-factor, and bifactor (S-1) models were compared in a sample of 799 participants at age 30. Measurement invariance was tested using multigroup confirmatory factor analyses iteratively in four steps (i.e., configural, thresholds, thresholds and loadings/strong) across sex (male; female) and language of questionnaire completion (English; French). Invariance across time was tested among 633 participants with data at ages 30, 34 and 35.</div></div><div><h3>Results</h3><div>A one-factor model showed the best fit. Partial strong invariance across sex and full strong invariance across language of the one-factor model was demonstrated. Strong invariance across time was also demonstrated, indicating stability in parameters over time for the same participants ages 30 to 35.</div></div><div><h3>Limitations</h3><div>The results are restricted to young adults and may not generalize to wider age ranges. Participants are predominantly born in Canada and report high levels of education and employment.</div></div><div><h3>Conclusion</h3><div>The one-factor structure of the GAD-7 demonstrated measurement invariance across sex, language, and time in young adults.</div></div>","PeriodicalId":14963,"journal":{"name":"Journal of affective disorders","volume":"375 ","pages":"Pages 359-365"},"PeriodicalIF":4.9,"publicationDate":"2025-01-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143065580","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Obsessive-compulsive symptoms in individuals with a history of eating disorders","authors":"Avantika Kapadia ,&nbsp;Laura M. Thornton ,&nbsp;Melissa A. Munn-Chernoff ,&nbsp;Amitai Abramovitch ,&nbsp;Dean McKay ,&nbsp;Jonathan S. Abramowitz ,&nbsp;Zeynep Yilmaz ,&nbsp;James J. Crowley ,&nbsp;Cynthia M. Bulik ,&nbsp;Hunna J. Watson","doi":"10.1016/j.jad.2025.01.068","DOIUrl":"10.1016/j.jad.2025.01.068","url":null,"abstract":"<div><h3>Background</h3><div>OCD symptoms are well documented in anorexia nervosa (AN) and to a lesser extent in bulimia nervosa (BN), yet remain virtually unstudied in binge-eating disorder (BED).</div></div><div><h3>Methods</h3><div>In this cross-sectional observational study, 5927 participants with lifetime eating disorders (EDs) (i.e., past or current) were categorized into five groups based on their diagnostic histories: AN only (<em>n</em> = 2330), BN only (<em>n</em> = 740), BED only (<em>n</em> = 665), AN and another ED diagnosis (AN Mixed) (<em>n</em> = 1293), and BN and BED (BN-BED) (<em>n</em> = 899). Obsessive-Compulsive Inventory-12 scores were compared across these groups and with OCD (<em>n</em> = 1040), anxiety-related disorders (ANX) (<em>n</em> = 423), and non-clinical community (NCC) (<em>n</em> = 1194) cohorts.</div></div><div><h3>Results</h3><div>OCD symptoms were common among individuals with lifetime AN, BN, BED, and multiple EDs, with obsessing being the most prevalent dimension, followed by ordering, checking, and washing. The obsessing scale, which captures general intrusive thoughts rather than traditional OCD obsessions, was notably high. ED groups generally scored higher on the OCI-12 subscales than the ANX and NCC cohorts but lower than the OCD cohort, although ordering severity was higher in some ED groups. Positive correlations were found between ED symptoms and OCI-12 subscales, and gender-diverse individuals and men had greater OCD symptoms than women.</div></div><div><h3>Conclusions</h3><div>Clinicians should be vigilant for OCD symptoms in individuals with AN, BN, and BED. These findings call for research on the mechanisms linking EDs and OCD symptoms and support integrated treatment approaches for both conditions.</div></div>","PeriodicalId":14963,"journal":{"name":"Journal of affective disorders","volume":"375 ","pages":"Pages 496-507"},"PeriodicalIF":4.9,"publicationDate":"2025-01-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143046821","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}