Lorenzo Fregna, Francesco Attanasio, Cristina Colombo
{"title":"Corrigendum to \"Evaluating the impact of adjunct bright light therapy on subjective sleep quality in major depressive disorder\" [J. Affect. Disord. 348 (2024) 175-178].","authors":"Lorenzo Fregna, Francesco Attanasio, Cristina Colombo","doi":"10.1016/j.jad.2025.119688","DOIUrl":"10.1016/j.jad.2025.119688","url":null,"abstract":"","PeriodicalId":14963,"journal":{"name":"Journal of affective disorders","volume":" ","pages":"119688"},"PeriodicalIF":4.9,"publicationDate":"2025-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144333196","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Corrigendum to \"Increased prevalence of depression, anxiety, and adjustment and somatoform disorders in transsexual individuals\" [J. Affect. Disord. 274 (2020) 482-485].","authors":"Marcel Konrad, Karel Kostev","doi":"10.1016/j.jad.2025.119812","DOIUrl":"10.1016/j.jad.2025.119812","url":null,"abstract":"","PeriodicalId":14963,"journal":{"name":"Journal of affective disorders","volume":" ","pages":"119812"},"PeriodicalIF":4.9,"publicationDate":"2025-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144591214","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Alex F Martin, G James Rubin, M Brooke Rogers, Simon Wessely, Neil Greenberg, Charlotte E Hall, Angie Pitt, Poppy Ellis Logan, Rebecca Lucas, Samantha K Brooks
{"title":"The changing prevalence of ADHD? A systematic review.","authors":"Alex F Martin, G James Rubin, M Brooke Rogers, Simon Wessely, Neil Greenberg, Charlotte E Hall, Angie Pitt, Poppy Ellis Logan, Rebecca Lucas, Samantha K Brooks","doi":"10.1016/j.jad.2025.119427","DOIUrl":"10.1016/j.jad.2025.119427","url":null,"abstract":"<p><strong>Introduction: </strong>Understanding the prevalence of Attention Deficit Hyperactivity Disorder (ADHD) and changes in demand for related healthcare services is crucial for effective healthcare policy and resource allocation. Clinicians, teachers and charities have reported increasing demand for ADHD assessments in recent years, overwhelming support systems. This review synthesises post-2020 studies of ADHD prevalence and incidence.</p><p><strong>Methods: </strong>We conducted systematic searches in Web of Science, Embase, Medline, Global Health, and PsycInfo using terms relating to ADHD and prevalence. Additional sources included public health databases, Google, and study reference lists. Studies were included if they contained original data relating to general population rates of ADHD and we extracted data relating to methods of assessment and measures of prevalence and incidence. We followed PRISMA and synthesis without meta-analysis (SWiM) guidelines.</p><p><strong>Results: </strong>Forty studies across 17 countries, with one study spanning 42 countries, were reviewed. No significant rise in ADHD prevalence was found, although incidence was found to vary during the COVID-19 pandemic. Only four of the included studies were at low risk of bias.</p><p><strong>Limitations: </strong>There are substantial limitations in the quality of the literature included in this review. Due to significant delays in reporting prevalence data, estimates from previous reviews may be inaccurate. There is a lack of healthcare data and no school-level data.</p><p><strong>Conclusions: </strong>Significant research gaps exist in determining ADHD prevalence and incidence. The highest quality findings do not suggest an increase in prevalence since 2020 but indicate some variability in incidence during the COVID-19 pandemic. Further research is urgently needed to guide clinical practice and public health policy.</p>","PeriodicalId":14963,"journal":{"name":"Journal of affective disorders","volume":" ","pages":"119427"},"PeriodicalIF":4.9,"publicationDate":"2025-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144110695","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Jemimah Ride, Li Huang, Melissa Mulraney, Harriet Hiscock, David Coghill, Michael Sawyer, Emma Sciberras, Kim Dalziel
{"title":"Corrigendum to \"Is 'minimally adequate treatment' really adequate? investigating the effect of mental health treatment on quality of life for children with mental health problems\" [J. Affect. Disord. 276 (2020) 327-334].","authors":"Jemimah Ride, Li Huang, Melissa Mulraney, Harriet Hiscock, David Coghill, Michael Sawyer, Emma Sciberras, Kim Dalziel","doi":"10.1016/j.jad.2025.119691","DOIUrl":"10.1016/j.jad.2025.119691","url":null,"abstract":"","PeriodicalId":14963,"journal":{"name":"Journal of affective disorders","volume":" ","pages":"119691"},"PeriodicalIF":4.9,"publicationDate":"2025-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144340133","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ronen Sosnik , Antoine Bertrand , Muli Linder , Mircea Polosan
{"title":"Event-related potential alterations in bipolar disorder subtypes and mood states: Insights from an emotional visual task","authors":"Ronen Sosnik , Antoine Bertrand , Muli Linder , Mircea Polosan","doi":"10.1016/j.jad.2025.119970","DOIUrl":"10.1016/j.jad.2025.119970","url":null,"abstract":"<div><h3>Background</h3><div>Event-related potentials (ERPs) offer insights into neural mechanisms underlying bipolar disorder (BD), but their role as stable trait markers or state-dependent indicators remains unclear.</div></div><div><h3>Methods</h3><div>We examined six participant groups: healthy controls, individuals with BD I and II in depressed or euthymic states, and their unaffected siblings during an emotional visual task. Participants viewed images with negative, positive, or neutral emotional valence, each surrounded by a green or red frame. They were instructed to press a key matching the frame's color. EEG data were recorded, and effects of participant group and emotional valence on task performance and ERP characteristics (amplitude and latency) were evaluated using linear mixed-effects models, corrected for age and gender.</div></div><div><h3>Results</h3><div>Response time showed a significant group × condition interaction (Δχ<sup>2</sup>(22) = 34.33, <em>p</em> < 0.001), with predicted RTs from 579 ms (95 % CI: 452–743) for the BD_II euthymic group in the neutral condition to 829 ms (95 % CI: 732–940) for BD_I depressed participants in the negative condition; however, no post hoc differences remained significant after FDR correction. Early (N200) and late (LPP; 600–1000 ms) ERP amplitudes varied by condition, and P300 latency differed between groups, with unaffected siblings showing ERP alterations compared to controls.</div></div><div><h3>Conclusion</h3><div>BD, its subtypes, and mood states exert distinct effects on early and late ERP characteristics during emotional processing. These findings support the potential use of ERP features from emotional tasks as diagnostic markers for BD and highlight the complex interplay between trait and state factors in BD's neurophysiological profile.</div></div>","PeriodicalId":14963,"journal":{"name":"Journal of affective disorders","volume":"391 ","pages":"Article 119970"},"PeriodicalIF":4.9,"publicationDate":"2025-07-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144703963","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Zonglin Shen , Yi Li , Xiaoyan Liu , Lijin Yuan , Yun Zhu , WenYu Li , Yiyun Wang , Xiaoyun Luo , Jigang Lian , Shuran Yang
{"title":"The effects of melancholic features on the efficacy of high-frequency rTMS in adolescents and young adults with major depressive disorder","authors":"Zonglin Shen , Yi Li , Xiaoyan Liu , Lijin Yuan , Yun Zhu , WenYu Li , Yiyun Wang , Xiaoyun Luo , Jigang Lian , Shuran Yang","doi":"10.1016/j.jad.2025.119954","DOIUrl":"10.1016/j.jad.2025.119954","url":null,"abstract":"<div><h3>Objective</h3><div>This research examined the effects of neuronavigated high-frequency repetitive transcranial magnetic stimulation (HF-rTMS) on adolescents and young adults with major depressive disorder (AYA-MDD) with melancholic features. It also explored neuroimaging differences between melancholic (MD) and non-melancholic (NMD) AYA-MDD subtypes.</div></div><div><h3>Method</h3><div>Forty-four AYA-MDD participants (14 MD, 30 NMD) underwent 10 daily HF-rTMS sessions over two weeks. Resting-state fMRI scans were conducted pre- and post-treatment on 35 individuals (13 MD). The default mode network (DMN) was analyzed via independent component analysis (ICA). Depressive symptoms were measured using the HDRS-17 and three dimensions: somatic disturbances (SoD), core mood/anhedonia (CMA), and insomnia.</div></div><div><h3>Result</h3><div>SoD and insomnia improved significantly by week 1, while CMA showed improvement after two weeks. No between-group outcome differences were found. MD patients had baseline hyperactivity in the right frontal gyrus and hypoactivity in the right precuneus compared to healthy controls (HC). NMD patients showed right frontal gyrus hyperactivity and right cuneus hypoactivity relative to HC. MD patients also had greater right frontal gyrus activity and lower right precuneus activity than NMD patients. Post-treatment, MD patients exhibited increased left precuneus/cuneus activity, while NMD patients showed reduced left middle frontal gyrus/right angular gyrus activity. No correlations emerged between brain regions and HDRS-6 reduction.</div></div><div><h3>Conclusion</h3><div>Melancholic features may delay early HF-rTMS response, necessitating at least two weeks of treatment for core symptom relief. While pre/post-treatment brain changes differed between groups, DMN posterior region modulation appears central to rTMS therapeutic effects.</div></div>","PeriodicalId":14963,"journal":{"name":"Journal of affective disorders","volume":"391 ","pages":"Article 119954"},"PeriodicalIF":4.9,"publicationDate":"2025-07-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144703962","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Amirabbas Mollaei, Vahid Zamanzadeh, Fatemeh Ranjbar Noei, Mahsa Kamali
{"title":"Cardiac patients' death anxiety: A systematic review and meta-analysis.","authors":"Amirabbas Mollaei, Vahid Zamanzadeh, Fatemeh Ranjbar Noei, Mahsa Kamali","doi":"10.1016/j.jad.2025.119967","DOIUrl":"https://doi.org/10.1016/j.jad.2025.119967","url":null,"abstract":"<p><p>Death anxiety (DA) is a critical psychological concern among patients with cardiovascular diseases (CVDs), yet its prevalence and associated factors remain understudied. This systematic review and meta-analysis aimed to determine the level of DA in cardiac patients and identify contributing factors. A comprehensive search of PubMed, Scopus, Web of Science, and Google Scholar yielded 27 cross-sectional studies (5292 participants). Studies were assessed using the AXIS tool, with most rated as high quality. Pooled estimates revealed moderate DA levels across studies, with mean scores of 8.46 (95 % CI: 7.05-9.86) for the Templer Death Anxiety Scale (TDAS) 0-15 range and 45.07 (95 % CI: 34.59-55.55) for the 15-75 range. Subgroup analyses indicated higher DA in Turkey (vs. Iran) and among coronary artery bypass graft (CABG) patients. Key factors linked to elevated DA included female gender, younger age, economic hardship, unemployment, reduced resilience, and diminished religious beliefs. Meta-regression found no significant moderation by age, sample size, or gender. These findings determine the need for targeted psychological interventions addressing modifiable factors like socioeconomic support and resilience-building in cardiac care. Limitations include reliance on cross-sectional data and heterogeneity in measurement tools. Future research should explore longitudinal and culturally diverse cohorts to clarify causal relationships and optimize DA management strategies.</p>","PeriodicalId":14963,"journal":{"name":"Journal of affective disorders","volume":" ","pages":"119967"},"PeriodicalIF":4.9,"publicationDate":"2025-07-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144707557","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Comments on “Development and validation of a predictive model for depression in patients with advanced stage of cardiovascular-kidney-metabolic syndrome”","authors":"Zhenhao Lin , Young-Je Sim , Yuwen Shangguan","doi":"10.1016/j.jad.2025.119966","DOIUrl":"10.1016/j.jad.2025.119966","url":null,"abstract":"","PeriodicalId":14963,"journal":{"name":"Journal of affective disorders","volume":"391 ","pages":"Article 119966"},"PeriodicalIF":4.9,"publicationDate":"2025-07-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144704217","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Concerns regarding scope and methodological framing in \"Mining the risk factors for stroke occurrence and dietary protective factors based on the NHANES database: Analysis using SHAP\".","authors":"Juan Manuel Marquez-Romero","doi":"10.1016/j.jad.2025.119963","DOIUrl":"https://doi.org/10.1016/j.jad.2025.119963","url":null,"abstract":"","PeriodicalId":14963,"journal":{"name":"Journal of affective disorders","volume":" ","pages":"119963"},"PeriodicalIF":4.9,"publicationDate":"2025-07-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144698646","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Boris van Passel , Unna N. Danner , Merijn Eikelenboom , Koen R.J. Schruers , Patricia van Oppen , Eni S. Becker , Gert-Jan Hendriks , Daniëlle C. Cath
{"title":"The double battle: comparing the six-year course of obsessive-compulsive disorder with and without comorbid eating disorder","authors":"Boris van Passel , Unna N. Danner , Merijn Eikelenboom , Koen R.J. Schruers , Patricia van Oppen , Eni S. Becker , Gert-Jan Hendriks , Daniëlle C. Cath","doi":"10.1016/j.jad.2025.119922","DOIUrl":"10.1016/j.jad.2025.119922","url":null,"abstract":"<div><h3>Background</h3><div>Eating disorders (ED) are more prevalent in individuals with obsessive-compulsive disorder (OCD), and their co-occurrence is associated with higher symptom-severity, increased risk of additional comorbidities, including depression, and poorer treatment outcomes. However, little is known about the long-term course of OCD in patients with versus without comorbid ED. This study investigated the 6-year clinical course of OCD symptom-severity in patients with (OCD + ED) and without (OCD-ED) lifetime ED.</div></div><div><h3>Methods</h3><div>Within the Netherlands OCD Association (NOCDA) cohort, 382 participants with a DSM-IV OCD diagnosis were classified as OCD + ED (<em>n</em> = 46; 91 % women; mean age 34.5) or OCD-ED (<em>n</em> = 336; 52 % women; mean age 36.6). Lifetime ED diagnoses included anorexia nervosa (39 %) and binge-eating disorder (37 %). OCD and ED diagnoses, symptom severity, and clinical/demographic variables were assessed at baseline and after two, four, and six years. Linear mixed-effects models were used to examine group differences in OCD symptom trajectories.</div></div><div><h3>Results</h3><div>OCD + ED participants showed higher baseline obsessive-compulsive, depressive, and anxiety symptoms, and more comorbid posttraumatic stress disorder than OCD-ED patients. Despite these differences, both groups followed a comparable 6-year course of OCD symptom severity, with no significant between-group differences in symptom reduction. Y-BOCS scores decreased by 4.17 points in OCD-ED and 5.24 in OCD + ED; PADUA scores declined by 13.68 and 15.65 points, respectively.</div></div><div><h3>Conclusion</h3><div>While OCD + ED patients showed a more significant clinical burden, comorbid ED did not significantly moderate long-term OCD symptom trajectories, suggesting a need for more intensive and/or longer treatment. The relatively small size of the OCD + ED group may be considered a limitation.</div></div>","PeriodicalId":14963,"journal":{"name":"Journal of affective disorders","volume":"391 ","pages":"Article 119922"},"PeriodicalIF":4.9,"publicationDate":"2025-07-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144687550","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}