Journal of Animal Science and Technology最新文献

{"title":"Erratum to: Effect of dietary natural phytoncide on blood characteristics to lipopolysaccharide challenge of Hanwoo cattle.","authors":"Bohye Park, Donghun Kang, Sunsik Jang, Uihyung Kim, Jongkyoo Kim, Bonghwan Choi, Seungchang Kim, Kiyong Chung","doi":"10.5187/jast.2500108.e","DOIUrl":"https://doi.org/10.5187/jast.2500108.e","url":null,"abstract":"<p><p>[This corrects the article DOI: 10.5187/jast.2500108.].</p>","PeriodicalId":14923,"journal":{"name":"Journal of Animal Science and Technology","volume":"68 1","pages":"371"},"PeriodicalIF":3.2,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12932035/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147306260","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"<i>Aporocactus flagelliformis</i> water extract and limonin suppresses P2Y purinoceptor 14-mediated proinflammatory features in 3D4/31 porcine alveolar macrophages.","authors":"Hyungkuen Kim, Hyun Sik Jun, Ki-Duk Song, Sung-Jo Kim","doi":"10.5187/jast.2024.e103","DOIUrl":"10.5187/jast.2024.e103","url":null,"abstract":"<p><p>Respiratory diseases have been recognized as a significant cause of reduced livestock productivity since 1995. Respiratory diseases in the swine industry caused by both biological and non-biological factors are collectively referred to as porcine respiratory disease complex (PRDC). However, there is a lack of eco-friendly anti-inflammatory drugs (AIDs) that can effectively control lung inflammation caused by PRDC. P2Y purinoreceptor 14 (P2Y₁₄) has been identified as a key regulator of macrophage inflammatory responses; however, its regulatory role in porcine lung inflammation remains unclear. In this study, we investigated the role of P2Y₁₄ in inflammation in 3D4/31 porcine macrophages and attempted to develop a novel AID. An extract of the Mexican medicinal plant <i>Aporocactus</i> flagelliformis water extract (AFWE) reduced reactive oxygen species production and pro-inflammatory cytokine expression in phorbol myristate acetate-stimulated 3D4/31-PAMs. It also reduced glucose uptake, glycogen accumulation, and expression of genes related to the P2Y₁₄ cascade. Polarity-based fractionation and liquid chromatography-mass spectrometry identified limonin as an anti-inflammatory compound in AFWE. Limonin reduced P2RY₁₄ and proinflammatory gene expression induced by the P2Y₁₄ ligand UDPG in 3D4/31-PAMs, demonstrating its inhibitory effect on P2Y₁₄-mediated inflammation. These results suggest that P2Y₁₄ is an inflammatory receptor in PAMs and an effective target for AID development. We also propose AFWE and limonin as candidate AIDs for pigs.</p>","PeriodicalId":14923,"journal":{"name":"Journal of Animal Science and Technology","volume":"68 1","pages":"219-235"},"PeriodicalIF":3.2,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12902472/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146201836","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Impact of naturally derived preservatives in sausage during refrigerated storage.","authors":"Jae Hoon Lee, Min Kyung Park, Yea-Ji Kim, Tae-Kyung Kim, Ji Yoon Cha, Su-Kyung Ku, Seung-Hye Woo, Heeyoung Lee, Jung-Min Sung, Min-Cheol Kang, Yun-Sang Choi","doi":"10.5187/jast.2024.e109","DOIUrl":"10.5187/jast.2024.e109","url":null,"abstract":"<p><p>In the present study, we developed a general-purpose preservative using natural extracts to reduce the residual toxicity and negative health effects of chemical preservatives. This study was conducted to improve the yield of optimized extracts of <i>Psidium guajava</i>, <i>Ecklonia cava</i>, and <i>Paeonia japonica</i> (Makino) Miyabe & Takeda extracts, which have already proven to exert antibacterial effects and verify their effectiveness in meat products. Ultrasonic extraction, a well-known eco-friendly extraction method, was performed to confirm the extraction yield, content of bioactive compounds in the extract, and antimicrobial activity and thus improve the extraction yield of the ethanol extract. In addition, ultrasound extraction was applied to sausages to confirm quality characteristics, including sensory evaluation. The extraction yield increased by 56.8% (<i>P. guajava</i>), 182.0% (<i>E. cava</i>), and 235.0% (<i>Paeonia japonica</i>) compared to the ethanol obtained through ultrasonic extraction of three types of natural products. Furthermore, a 32.53% increase in the extraction yield for the mixture extract was obtained through ultrasonic extraction. The MIC and MBC results for foodborne pathogens to measure the antimicrobial activity demonstrated that extracts obtained through ultrasonic extraction exhibited increased antimicrobial activity against certain pathogens. Total plate counts, Coliform, and <i>Escherichia coli</i> were not detected in all treatments in the sausage storage experiment (4 weeks). Although no significant difference was noted in the VBN of sausages among all treatments during the storage period (4 weeks), TBARS during storage was significantly lower in the natural extract treatments. Among the sensory characteristic evaluations, the overall acceptance scores were significantly higher for <i>P. guajava</i>, <i>E. cava</i>, and <i>Paeonia japonica</i> (Makino) Miyabe & Takeda extracts than for the grapefruit seed extract. Altogether, the extraction yield of <i>P. guajava</i>, <i>E. cava</i>, and <i>Paeonia japonica</i> (Makino) Miyabe & Takeda extracts was improved by about 32.53%, and almost the same effect was confirmed in the sausage application test.</p>","PeriodicalId":14923,"journal":{"name":"Journal of Animal Science and Technology","volume":"68 1","pages":"273-289"},"PeriodicalIF":3.2,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12902637/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146201597","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prospects of feed additive incorporation in laying hen diets: a narrative review of principal biological effects and recent developments.","authors":"Elijah Ogola Oketch, Jung Min Heo","doi":"10.5187/jast.2500369","DOIUrl":"10.5187/jast.2500369","url":null,"abstract":"<p><p>Selected feed additives (probiotics, prebiotics, synbiotics, postbiotics, phytogenics, feed enzymes, and organic acids) are reviewed for reported biological responses, and some recent developments when incorporated into laying hen diets. Several feed enzymes (phytase, carbohydrase, protease, and multi-enzymes) have been adopted to improve the nutritive quality of feedstuffs by mitigating inherent digestive function inefficiencies, complementing endogenous enzyme activity, and cleaving anti-nutritional factors abundant in vegetable-based poultry diets. Phytase use is targeted at hydrolyzing phytate to liberate phosphorus and possibly other encapsulated nutrients, with widely reported environmental and economic benefits. Proteases often improve the hydrolysis of amino acids and protein complexes to improve dietary protein digestibility and utilization, potentially restoring performance losses and maintaining the egg quality of hens fed low-protein diets whose CP level has been further reduced. The digestibility-enhancing effects of fiber-degrading carbohydrases are associated with the reduction of intestinal viscosity and improved energy utilization through depolymerization of soluble non-starch polysaccharides. Considering that nutrients exist in a complex matrix involving starch and non-starch polysaccharides, protein, lipids, minerals, and vitamins, laying hens could also benefit from potential additive and synergistic effects accrued from adopting defined feed enzyme combinations. The incorporation of gut-health-promoting feed additives (pre, pro, syn- and postbiotics, phytogenics, organic acids) optimizes feed nutrient utilization by inducing immuno-stimulatory, antimicrobial, and antioxidant activities, modulating gut immune function, and microbial balance and population. Hen responses to feed additives are context-dependent and highly variable due to various factors, including rearing system, age, breed, health status, environmental factors, feed composition and quality, and management. However, on balance, feed additive products with proven efficacy and financial value are recommended for inclusion in laying hen diets; and could potentiate optimized performance and egg quality, reduced feed costs, improved animal welfare and skeletal health, and reduced environmental stress due to nutrient excretion, thereby improving the economic and environmental sustainability of hen egg production. Strategic application of feed additive combinations could potentiate additive and synergistic responses.</p>","PeriodicalId":14923,"journal":{"name":"Journal of Animal Science and Technology","volume":"68 1","pages":"50-71"},"PeriodicalIF":3.2,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12902584/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146201600","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Non-destructive evaluation of microbial quality of beef (<i>M. longissimus thoracis</i> muscle) using visible/NIR hyperspectral imaging and machine learning methods.","authors":"Seongmin Park, Suk-Ju Hong, Chang-Hyup Lee, EungChan Kim, Sang-Yeon Kim, Cheorun Jo, Ghiseok Kim","doi":"10.5187/jast.2024.e110","DOIUrl":"10.5187/jast.2024.e110","url":null,"abstract":"<p><p>Machine learning models were developed to predict the degree of microbial quality of beef by a non-destructive method using a near-infrared hyperspectral imaging system. Beef was stored under aerobic conditions at different temperature scenarios (refrigerated, thawed after freezing, or left at room temperature) for a period of 15 days to induce freshness change and microbial growth. Hyperspectral data cubes were obtained from a data acquisition system in a darkroom environment. The total aerobic bacteria (TAB) experiment was performed in the established meat science manner to provide reference values for the microbial contamination level of the sample. The region of interest designated as the red meat region was selected for spectral extraction. Regression models were developed to predict the TAB value from the extracted data. Partial least squares regression, support vector machine, artificial neural network, and one-dimensional convolutional neural network methods were employed to construct TAB prediction models. Chemical maps were also created for each developed model to visualize the performance of the model. The model development process concluded with the iteration of all previous steps at completely different times and with different beef samples, generating the data for verification and applying it to the developed model to evaluate its versatility. As a result of the development, it was confirmed that the microbial quality of beef can be predicted by models generated from hyperspectral data (Best validation <i>R</i> ² = 0.8593, RMSE = 0.6947). Accurate quality prediction helps livestock breeders develop and apply better husbandry practices, which ultimately leads to higher quality beef production.</p>","PeriodicalId":14923,"journal":{"name":"Journal of Animal Science and Technology","volume":"68 1","pages":"290-305"},"PeriodicalIF":3.2,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12902639/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146201666","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effects of varying levels of β-mannanase on growth performance, nutrient digestibility, blood metabolites and diarrhea incidence in weaning pigs.","authors":"Minhyuk Jang, Minsoo Park, Yoo Yong Kim","doi":"10.5187/jast.2024.e100","DOIUrl":"10.5187/jast.2024.e100","url":null,"abstract":"<p><p>This study was carried out to examine the effects of varying levels of β-mannanase supplementation in corn-soybean meal (SBM)-based diet on growth performance, nutrient digestibility, blood metabolites, and diarrhea incidence of weaning pigs. A total of 160 pigs with an initial body weight (BW) of 8.66 ± 0.060 kg were used in the experiment. Using a randomized complete block (RCB) design, they were assigned to 4 treatments with 5 replicates and 8 pigs per pen, considering sex and initial BW. Treatments for early (0-2 weeks) and late weaning phases (2-5 weeks) were as follows: β-Man0: corn-SBM-based basal diet + β-mannanase 0%; β-Man0.05: basal diet + β-mannanase 0.05%; β-Man0.1: basal diet + β-mannanase 0.1%; and β-Man0.15: basal diet + β-mannanase 0.15%. During the early weaning phase, average daily gain tended to increase when β-mannanase level increased (linear, <i>p</i> = 0.07). When β-mannanase level increased in the late weaning phase, the average daily feed intake tended to decrease (linear, <i>p</i> = 0.08), and gain to feed ratio (G:F ratio) increased (linear, <i>p</i> = 0.02). Throughout the whole experimental period, G:F ratio tended to increase as β-mannanase level increased (linear, <i>p</i> = 0.06). According to nutrient digestibility, crude fat digestibility increased when the β-mannanase level increased (linear, <i>p</i> = 0.04). Accordingly, the total protein and triglyceride concentration increased as β-mannanase level increased in the early weaning phase (linear, <i>p</i> = 0.01; <i>p</i> = 0.01). During the entire experimental period, the total cholesterol concentration increased significantly (linear, <i>p</i> < 0.01), whereas the high-density lipoprotein cholesterol and low-density lipoprotein cholesterol concentration increased with higher levels of β-mannanase (linear, <i>p</i> = 0.02; <i>p</i> = 0.02). Lastly, diarrhea incidence showed no significant variation during the early and late weaning phases according to β-mannanase levels. As the level of β-mannanase supplementation in the weaning pig diet increased, growth performance, nutrient digestibility, and blood metabolites showed some positive trends. Therefore, supplementing β-mannanase up to 0.15% in the diet of weaning pigs could enhance their productivity.</p>","PeriodicalId":14923,"journal":{"name":"Journal of Animal Science and Technology","volume":"68 1","pages":"139-150"},"PeriodicalIF":3.2,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12902578/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146201817","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Control of alkaline phosphatase activity and pH stability by taurine in liquid boar semen.","authors":"Wijesooriya Mudhiyanselage Nadeema Dissanayake, Malavi Arachchi Gamage Nayodya Dananjanee Malavi Arachchi Gamage, Jung Min Heo, Young-Joo Yi","doi":"10.5187/jast.2024.e90","DOIUrl":"10.5187/jast.2024.e90","url":null,"abstract":"<p><p>Alkaline phosphatase (ALP) is an enzyme present in various tissues and plays an important role in biochemical processes, by catalyzing the hydrolysis of organic phosphates and energy metabolism. Despite significant ALP activity in seminal plasma across species, its role in sperm function remains unclear. Several studies have revealed the important role of taurine in male reproductive functions, due to its antioxidant and membrane-stabilizing activity, and ability to enhance sperm quality. Therefore, this study examined the influence of taurine on ALP activity and pH stability in liquid boar semen during storage. Boar spermatozoa were exposed to different concentrations of ALP (0-5 IU/mL), and sperm motility, viability, acrosome integrity, and ALP activity were examined. In addition, liquid boar semen with varying concentrations of taurine (10-80 mM) was stored at 17°C for 7 days, and the ALP activity, pH level, and fertilization competence of spermatozoa were investigated through the storage period. Higher ALP activity was detected in fresh spermatozoa compared with capacitated spermatozoa. Motility, viability, and acrosome integrity decreased significantly in sperm incubated with 1-5 IU/mL ALP. An immunofluorescence assay revealed that ALP was localized on the acrosome, equatorial segment, and tail, and the fluorescence intensity indicated that ALP levels gradually decreased during storage. When the pH of liquid boar semen was maintained at 7.4 during storage, it showed higher ALP activity and sperm quality compared to sperm stored in a medium where pH was not maintained at a stable level. Also, when boar spermatozoa were stored in the diluent containing taurine, the pH and ALP activity were stable during the storage period. The generation of intracellular reactive oxygen species decreased in sperm stored with taurine, and higher levels of sperm motility and viability were observed. The expression of mRNA associated with fertilization competence was higher in the sperm stored with 40 mM taurine compared to that of sperm stored without taurine. Thus, it can be concluded that ALP activity and pH stability are crucial for maintaining sperm quality during liquid boar semen storage, and these factors can be regulated by the addition of taurine, suggesting its applicability in assisted reproductive techniques in mammals.</p>","PeriodicalId":14923,"journal":{"name":"Journal of Animal Science and Technology","volume":"67 6","pages":"1228-1241"},"PeriodicalIF":3.2,"publicationDate":"2025-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12715437/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145804453","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparative gut microbiota, growth performances, and cytokine indices in broiler chickens with or without litter.","authors":"Jin Young Jeong, Seol Hwa Park, Minji Kim, Hwan Ku Kang, Nam-Geon Park","doi":"10.5187/jast.2024.e82","DOIUrl":"10.5187/jast.2024.e82","url":null,"abstract":"<p><p>Developmental patterns of the gut microbiota are important for improving chicken health and productivity. However, the influence of litter and litter microbes on cecal microbiota is still unclear. This study aimed to identify broiler cecal microbiota at different ages according to litter usage in cage (without litter) and conventional (with litter) conditions. The cecal contents of the broilers from each group were collected from 1-5 wk. The development and function of the gut microbiota were evaluated using 16S rRNA gene sequencing. The final body weight of the chickens was higher in the cage group than that in the conventional group. In particularly, α-diversity was higher at 3 wk than that at 1 wk. The phyla Firmicutes predominated at 3 wk. In contrast, the abundance of Bacteroidetes and fibrinolytic bacteria increased significantly at 1 and 2 wk compared to that at 3 and 5 wk. <i>Corynebacterium</i> was the most abundant genus in the conventional group after 3 wk. In conclusion, the cecal microbiota are influenced by environmental factors, such as cage, which improves the chicken gut environment.</p>","PeriodicalId":14923,"journal":{"name":"Journal of Animal Science and Technology","volume":"67 6","pages":"1328-1342"},"PeriodicalIF":3.2,"publicationDate":"2025-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12715436/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145804486","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Supplementation effects of feed additive containing eggshell, <i>Schisandra chinensis</i> by-products combined with multi-probiotics strains in laying hens.","authors":"Ah-Ran Lee, Sol-Hee Kim, Hangsul Cho, Yan-Qing Wang, Soo-Ki Kim","doi":"10.5187/jast.2024.e119","DOIUrl":"10.5187/jast.2024.e119","url":null,"abstract":"<p><p>Eggshell waste and <i>Schisandra chinensis</i> by-products are natural sources rich in beneficial nutrients and bioactive compounds. However, their combined effects with multi-probiotics on poultry productivity and health remain unexplored. This study assessed the immediate effects of a feed additive-eggshell waste (ES), <i>Schisandra chinensis</i> by-product (SC), and multi-probiotics (M)-administered for four weeks to aged laying hens before slaughter, evaluating the improvements of laying performance, egg quality, blood characteristics, visceral organs, tibia, and cecal microbiota. A total of 216 Hy-line Brown laying hens (70-week-old) were assigned to four dietary treatments consisting of 9 replicates of 6 birds in a completely randomized design. The combination of eggshell waste, <i>Schisandra chinensis</i> by-product, and multi-probiotics (ESM) of feed additive consisted of 40% eggshell, 5% SC, and 10⁹-10¹¹ CFU/g of multi-probiotic strains including <i>Bacillus subtilis</i>, <i>Bacillus licheniformis</i>, <i>Saccharomyces cerevisiae</i>, <i>Lactobacillus plantarum</i>, and supplemental nutrient premix. The treatment groups were as follows: corn-soybean meal-based basal diet (control); basal diet + 0.1% ESM; basal diet + 0.2% ESM, basal diet + 0.4% ESM. The total egg productivity rate during the experiment period tended to improve in ESM 0.2%, as compared with the control. The ESM 0.1% group increased egg weight (<i>p</i> < 0.05) while ESM 0.1% and ESM 0.2% tended to increase egg mass, compared to the control (<i>p</i> = 0.051). However, there was no significant difference in egg weight, feed intake, feed conversion ratio, and egg quality among the treatments. Furthermore, blood characteristics did not differ between the treatments, except for the total cholesterol contents, which was higher in ESM 0.4% treatment than the control (<i>p</i> < 0.05). ESM 0.4% supplementation showed a tendency for higher calcium, compared to the control. ESM 0.4% supplementation showed higher bone mineral density (BMD) of the tibia neck than the control (<i>p</i> < 0.01). All three ESM groups demonstrated a significant decrease in the abundance of <i>Bacteroidaceae</i> (<i>p</i> < 0.05), and an increase in the abundance of <i>Lactobaillaceae</i> at the family level (<i>p</i> < 0.01). In conclusion, ESM fed hens showed beneficial effects on the egg weight, egg mass, BMD of tibia neck, and cecal microbiota in laying hens.</p>","PeriodicalId":14923,"journal":{"name":"Journal of Animal Science and Technology","volume":"67 6","pages":"1285-1301"},"PeriodicalIF":3.2,"publicationDate":"2025-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12715450/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145804474","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Application of dietary organic acids in laying hens production: a comprehensive review.","authors":"Jeseok Lee, Sehyeok Oh, Jung Min Heo","doi":"10.5187/jast.2500224","DOIUrl":"10.5187/jast.2500224","url":null,"abstract":"<p><p>The removal of antibiotic growth promoters from poultry diets has driven research into alternative feed additives to optimize production performance in laying hens. Among these alternatives, dietary organic acids (OAs) have gained significant attention due to their antimicrobial properties, ability to modulate intestinal acidity, and role in enhancing nutrient utilization. This review comprehensively examines the effects of OAs supplementation on egg production and quality, blood parameters, intestinal morphology, fecal and intestinal microbiota, and bone health in laying hens. Studies indicate that various OAs supplementation improves egg production and quality. Additionally, OAs contribute to superior eggshell quality by enhancing calcium and protein absorption. The physiological benefits of OAs supplementation include improved intestinal morphology, gut microbiota, and immune and physiological responses. On the other hand, the effectiveness of OAs varies depending on the type of acid, dosage, environmental conditions, and interactions with feed ingredients or additives. This review consolidates current findings to provide practical insights into the application of OAs as a viable alternative to AGPs in commercial laying hen production.</p>","PeriodicalId":14923,"journal":{"name":"Journal of Animal Science and Technology","volume":"67 6","pages":"1185-1206"},"PeriodicalIF":3.2,"publicationDate":"2025-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12715441/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145804498","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}