{"title":"Asthma remission.","authors":"Paul M O'Byrne","doi":"10.36416/1806-3756/e20240004","DOIUrl":"10.36416/1806-3756/e20240004","url":null,"abstract":"","PeriodicalId":14845,"journal":{"name":"Jornal Brasileiro De Pneumologia","volume":"50 1","pages":"e20240004"},"PeriodicalIF":2.9,"publicationDate":"2024-03-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11095932/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140305671","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Simone Lobo Krupok Matias, Carlos Alberto de Castro Pereira, Maria Raquel Soares, Flávia Castro Velasco Fernandes, Maria Auxiliadora Carmo Moreira, Fernanda Maciel de Aguiar Baptista, Tarciane Aline Prata, Gediel Cordeiro Junior, Eliane Viana Mancuzo
{"title":"Relative incidence of interstitial lung diseases in Brazil.","authors":"Simone Lobo Krupok Matias, Carlos Alberto de Castro Pereira, Maria Raquel Soares, Flávia Castro Velasco Fernandes, Maria Auxiliadora Carmo Moreira, Fernanda Maciel de Aguiar Baptista, Tarciane Aline Prata, Gediel Cordeiro Junior, Eliane Viana Mancuzo","doi":"10.36416/1806-3756/e20230232","DOIUrl":"10.36416/1806-3756/e20230232","url":null,"abstract":"<p><strong>Objective: </strong>To assess the relative frequency of incident cases of interstitial lung diseases (ILDs) in Brazil.</p><p><strong>Methods: </strong>This was a retrospective survey of new cases of ILD in six referral centers between January of 2013 and January of 2020. The diagnosis of ILD followed the criteria suggested by international bodies or was made through multidisciplinary discussion (MDD). The condition was characterized as unclassifiable ILD when there was no specific final diagnosis following MDD or when there was disagreement between clinical, radiological, or histological data.</p><p><strong>Results: </strong>The sample comprised 1,406 patients (mean age = 61 ± 14 years), and 764 (54%) were female. Of the 747 cases exposed to hypersensitivity pneumonitis (HP)-related antigens, 327 (44%) had a final diagnosis of HP. A family history of ILD was reported in 8% of cases. HRCT findings were indicative of fibrosis in 74% of cases, including honeycombing, in 21%. Relevant autoantibodies were detected in 33% of cases. Transbronchial biopsy was performed in 23% of patients, and surgical lung biopsy, in 17%. The final diagnoses were: connective tissue disease-associated ILD (in 27%), HP (in 23%), idiopathic pulmonary fibrosis (in 14%), unclassifiable ILD (in 10%), and sarcoidosis (in 6%). Diagnoses varied significantly among centers (c2 = 312.4; p < 0.001).</p><p><strong>Conclusions: </strong>Our findings show that connective tissue disease-associated ILD is the most common ILD in Brazil, followed by HP. These results highlight the need for close collaboration between pulmonologists and rheumatologists, the importance of detailed questioning of patients in regard with potential exposure to antigens, and the need for public health campaigns to stress the importance of avoiding such exposure.</p>","PeriodicalId":14845,"journal":{"name":"Jornal Brasileiro De Pneumologia","volume":"50 1","pages":"e20230232"},"PeriodicalIF":2.9,"publicationDate":"2024-03-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11095929/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140305678","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Examining the incidence of interstitial lung disease subtypes in South America.","authors":"Kirsten Nesset, Martin Kolb","doi":"10.36416/1806-3756/e20240028","DOIUrl":"10.36416/1806-3756/e20240028","url":null,"abstract":"","PeriodicalId":14845,"journal":{"name":"Jornal Brasileiro De Pneumologia","volume":"50 1","pages":"e20240028"},"PeriodicalIF":2.9,"publicationDate":"2024-02-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11095918/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139996312","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pedro Nogueira Costa, João Oliveira Pereira, Aurea Higon Cañigral, Elena Martinez Quintana, Juan Miguel Sanchez-Nieto, Pablo Bayoumy Delis, Ana Renedo Villarroya, Laura Lopez Gomez, Nuria Alonso Fernandez, Andrés Carrillo Alcaraz
{"title":"Vaccination status and outcomes in critical COVID-19 patients.","authors":"Pedro Nogueira Costa, João Oliveira Pereira, Aurea Higon Cañigral, Elena Martinez Quintana, Juan Miguel Sanchez-Nieto, Pablo Bayoumy Delis, Ana Renedo Villarroya, Laura Lopez Gomez, Nuria Alonso Fernandez, Andrés Carrillo Alcaraz","doi":"10.36416/1806-3756/e20230116","DOIUrl":"10.36416/1806-3756/e20230116","url":null,"abstract":"<p><strong>Objective: </strong>To analyze the clinical characteristics and outcomes of patients with COVID-19-related acute respiratory failure on the basis of their vaccination status at the time of ICU admission.</p><p><strong>Methods: </strong>We conducted a retrospective observational study using a prospective database of patients admitted to the ICU of a university hospital in the city of Murcia, in Spain, between January 1, 2021 and September 1, 2022. Clinical, analytical, and sociodemographic data were collected and analyzed on the basis of patient vaccination status. We adjusted for confounding variables using propensity score matching and calculated adjusted ORs and 95% CIs.</p><p><strong>Results: </strong>A total of 276 patients were included in the study. Of those, 8.3% were fully vaccinated, 12% were partially vaccinated, and 79.7% were unvaccinated. Although fully vaccinated patients had more comorbidities, partially vaccinated patients had higher disease severity. The proportion of patients with severe acute respiratory failure was higher in the unvaccinated group, followed by the partially vaccinated group. No significant differences were found among the different groups regarding complications, duration of ventilatory support, or length of ICU/hospital stay. In the sample selected by propensity score matching, the number of patients with severe complications and the in-hospital mortality rate were higher in unvaccinated patients, but the differences were not significant.</p><p><strong>Conclusions: </strong>This study failed to show a significant improvement in outcomes in critically ill COVID-19 patients vaccinated against SARS-CoV-2. However, the CIs were wide and the mortality point estimates favored patients who received at least one dose of COVID-19 vaccine.</p>","PeriodicalId":14845,"journal":{"name":"Jornal Brasileiro De Pneumologia","volume":"50 1","pages":"e20230116"},"PeriodicalIF":2.9,"publicationDate":"2024-02-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11095925/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139996314","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Edson Marchiori, Bruno Hochhegger, Gláucia Zanetti
{"title":"Bullous emphysema in a cannabis user.","authors":"Edson Marchiori, Bruno Hochhegger, Gláucia Zanetti","doi":"10.36416/1806-3756/e20230352","DOIUrl":"10.36416/1806-3756/e20230352","url":null,"abstract":"","PeriodicalId":14845,"journal":{"name":"Jornal Brasileiro De Pneumologia","volume":"50 1","pages":"e20230352"},"PeriodicalIF":2.9,"publicationDate":"2024-02-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11095922/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139996311","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Andréa Mazza Beliero1,2, Ana Paula Pires Lázaro3,4, Marza de Sousa Zaranza1,5, Giovanna Mazza Cruz Lima4, Álvaro Rolim Guimarães5, Nilcyeli Linhares Aragão5, Gdayllon Cavalcante Meneses5, Marcelo Alcantara Holanda5,6, Polianna Lemos Moura Moreira Albuquerque4,7, Geraldo Bezerra da Silva Júnior3,4, Paula Frassinetti Castelo Branco Camurça Fernandes2
{"title":"ELMO CPAP: an innovative type of ventilatory support for COVID-19-related acute respiratory distress syndrome","authors":"Andréa Mazza Beliero1,2, Ana Paula Pires Lázaro3,4, Marza de Sousa Zaranza1,5, Giovanna Mazza Cruz Lima4, Álvaro Rolim Guimarães5, Nilcyeli Linhares Aragão5, Gdayllon Cavalcante Meneses5, Marcelo Alcantara Holanda5,6, Polianna Lemos Moura Moreira Albuquerque4,7, Geraldo Bezerra da Silva Júnior3,4, Paula Frassinetti Castelo Branco Camurça Fernandes2","doi":"10.36416/1806-3756/e20230227","DOIUrl":"https://doi.org/10.36416/1806-3756/e20230227","url":null,"abstract":"Objective: To assess whether the use of ELMO, a helmet for noninvasive ventilation created in Brazil, had a positive impact on the prognosis of patients with hypoxemic respiratory failure caused by severe COVID-19. Methods: This is a retrospective study of 50 critically ill COVID-19 patients. Epidemiological, clinical, and laboratory data were collected on ICU admission, as well as before, during, and after ELMO use. Patients were divided into two groups (success and failure) according to the outcome. Results: ELMO use improved oxygenation parameters such as Pao2, Fio2, and the Pao2/Fio2 ratio, and this contributed to a gradual reduction in Fio2, without an increase in CO2, as determined by arterial blood gas analysis. Patients in the success group had significantly longer survival (p < 0.001), as determined by the Kaplan-Meier analysis, less need for intubation (p < 0.001), fewer days of hospitalization, and a lower incidence of acute kidney injury in comparison with those in the failure group. Conclusions: The significant improvement in oxygenation parameters, the longer survival, as reflected by the reduced need for intubation and by the mortality rate, and the absence of acute kidney injury suggest that the ELMO CPAP system is a promising tool for treating ARDS and similar clinical conditions.","PeriodicalId":14845,"journal":{"name":"Jornal Brasileiro De Pneumologia","volume":"46 2","pages":""},"PeriodicalIF":2.7,"publicationDate":"2023-12-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139157188","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Increasing patient access to spirometry in the Unified Health System in Brazil: no longer a dream but a near reality","authors":"Ricardo Amorim Corrêa1,2, Eliane Viana Mancuzo1,2, Camila Farnese Rezende2, Antônio Luiz Pinho Ribeiro1,3","doi":"10.36416/1806-3756/e20230384","DOIUrl":"https://doi.org/10.36416/1806-3756/e20230384","url":null,"abstract":"","PeriodicalId":14845,"journal":{"name":"Jornal Brasileiro De Pneumologia","volume":"18 2","pages":""},"PeriodicalIF":2.7,"publicationDate":"2023-12-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138947529","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Laura Menestrino Prestes, Miguel Ângelo Uflacker Lutz de Castro, Gabriela de Azevedo Bastian de Souza, Laura Gomes Boabaid de Barros, Marcelo Comerlato Scotta, Leonardo Araujo Pinto
{"title":"Management of pneumonia and pleural effusion in children.","authors":"Laura Menestrino Prestes, Miguel Ângelo Uflacker Lutz de Castro, Gabriela de Azevedo Bastian de Souza, Laura Gomes Boabaid de Barros, Marcelo Comerlato Scotta, Leonardo Araujo Pinto","doi":"10.36416/1806-3756/e20230370","DOIUrl":"10.36416/1806-3756/e20230370","url":null,"abstract":"","PeriodicalId":14845,"journal":{"name":"Jornal Brasileiro De Pneumologia","volume":"49 6","pages":"e20230370"},"PeriodicalIF":2.7,"publicationDate":"2023-12-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10760440/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138829844","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
José Alberto Neder1, Danilo Cortozi Berton2, Denis E O’Donnell1
{"title":"Pulmonary function laboratory to assist in the management of cardiac disease","authors":"José Alberto Neder1, Danilo Cortozi Berton2, Denis E O’Donnell1","doi":"10.36416/1806-3756/e20230368","DOIUrl":"https://doi.org/10.36416/1806-3756/e20230368","url":null,"abstract":"","PeriodicalId":14845,"journal":{"name":"Jornal Brasileiro De Pneumologia","volume":"4 9","pages":""},"PeriodicalIF":2.7,"publicationDate":"2023-12-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138944779","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}