Journal de mycologie medicale最新文献

{"title":"Vulvovaginal candidiasis, an increasing burden to women in the tropical regions attending Bharatpur Hospital, Chitwan","authors":"Anisha Subedi ,&nbsp;Milan Kumar Upreti ,&nbsp;Jid Chani Rana ,&nbsp;Ram Prasad Sapkota ,&nbsp;Upendra Thapa Shrestha","doi":"10.1016/j.mycmed.2024.101509","DOIUrl":"10.1016/j.mycmed.2024.101509","url":null,"abstract":"<div><p>Vulvovaginal candidiasis is a yeast infection commonly caused by the overgrowth of <em>Candida</em> species in and around the vulva and vagina. Abnormal vaginal discharge, itching and irritation, swelling and redness of the vaginal area, pain during sexual intercourse, and dyspareunia are important clinical findings of the infection. Currently, the infection is one of the growing burdens to married women. Moreover, the infection with antifungal-resistant <em>Candida</em> species adds challenges to managing the disease. Hence, this study was conducted to identify the different <em>Candida</em> species causing vulvovaginal candidiasis and to determine its susceptibility pattern against different antifungal drugs. A hospital-based cross-sectional and quantitative study was conducted for the period of six months from September 2022 to March 2023 among symptomatic married women in the Gynecology and Obstetrics Department of Bharatpur Hospital, Chitwan. A total of 300 symptomatic cases were enrolled in the study. <em>Candida</em> species were isolated from vaginal swabs following standard microbiological procedures and antifungal susceptibility testing was performed with different antifungal agents. The total prevalence of vulvovaginal candidiasis was found to be 37.3 % (112/300). Among different isolates, <em>Candida albicans</em> was found to be the most predominant (52.6 %), followed by <em>Candida glabrata</em> (29.3 %) among non-<em>albicans</em>. Women from the age group 25–35 years were found to be more infected (47.3 %) and the relationship between contraceptive use and vulvovaginal candidiasis was found to be statistically significant (<em>p</em> &lt; 0.05). <em>Candida</em> species showed higher susceptibility toward Amphotericin-B (68.1 %), followed by fluconazole (Diflucan), and Clotrimazole (50.9 %). Whereas the least susceptibility was observed to Voriconazole (27.6 %) and Itraconazole (35.30 %). <em>Candida albicans</em> was comparatively more susceptible to different antifungal drugs than non-<em>albicans</em> species. <em>Candida parapsilosis</em> was only susceptible to Amphotericin-B and the increasing incidence of vaginal candidiasis due to non-<em>albicans Candida</em> indicates the need for routine speciation of <em>Candida.</em></p></div>","PeriodicalId":14824,"journal":{"name":"Journal de mycologie medicale","volume":"34 4","pages":"Article 101509"},"PeriodicalIF":2.2,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142230468","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Rumex japonicus Houtt. Leaves: The chemical composition and anti-fungal activity","authors":"Dandan Xiao ,&nbsp;He Sun ,&nbsp;Xue Li,&nbsp;Fanying Meng,&nbsp;Tong Sun,&nbsp;Xinting Shao,&nbsp;Yuling Ding,&nbsp;Yong Li","doi":"10.1016/j.mycmed.2024.101513","DOIUrl":"10.1016/j.mycmed.2024.101513","url":null,"abstract":"<div><h3>Background</h3><div><em>Candida albicans</em> is a pathogenic commensal fungus. <em>Trichophyton mentagrophytes</em> and <em>Trichophyton rubrum</em> are the leading pathogens of dermatophysis. <em>Rumex japonicus</em> Houtt. has a miraculous effect on the treatment of tinea skin disease, but its mechanism has not been clarified.</div></div><div><h3>Purpose</h3><div>This paper investigated the anti-fungal ingredients of the leaves of <em>Rumex japonicus</em> Houtt. (RJH-L) and the mechanism of the anti-fungal (<em>Trichophyton mentagrophytes, Trichophyton rubrum</em> and <em>Candida albicans</em>).</div></div><div><h3>Method</h3><div>First, the chemical composition analysis of RJH-L was conducted by acid extraction and alcohol precipitation, high performance liquid chromatography (HPLC) and nuclear magnetic resonance spectroscopy (NMR); in <em>vitro</em> anti-fungal experiments were carried out, including the minimum inhibitory concentration (MIC) and the minimum fungicidal concentration (MFC) spore germination rate, germ tube production rate, nucleic acid and protein leakage rate, biofilm structure, PCR, etc., to study the mechanism of action of RJH-L anti-fungal and anti-biofilm activity.</div></div><div><h3>Result</h3><div>Seven monomer compounds were obtained: anthraquinones (rhein, emodin and aloe-emodin); polyphenols (ferulic acid, <em>p-coumaric</em> acid), and flavonoids (rutin and quercetin). The results of in <em>vitro</em> anti-fungal experiments showed that the extracts of RJH-L had strong inhibitory effect on both fungi (MIC: 1.96 µg/mL-62.50 µg/mL), of which emodin had the strongest effect on <em>Trichophyton mentagrophytes</em>; and rhein had the strongest effect on <em>Candida albicans</em> and <em>Trichophyton rubrum</em>. The above active components can inhibit the germination of fungal spores and germ tube, change cell membrane permeability, prevent hyphal growth, destroy the biofilm structure, and down-regulate the expression of agglutinin-like sequencefamily1 of biofilm growth.</div></div><div><h3>Conclusion</h3><div>This study shows that RJH-L are rich in polyphenols, flavonoids, and anthraquinones, and play a fungicidal role.</div></div>","PeriodicalId":14824,"journal":{"name":"Journal de mycologie medicale","volume":"34 4","pages":"Article 101513"},"PeriodicalIF":2.2,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142578542","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Novel griseofulvin zinc nanohybrid emulsion for intensifying the antimicrobial control of dermatophytes and some opportunistic pathogens","authors":"Farag M. Mosallam ,&nbsp;Eman A. Helmy ,&nbsp;Hebatallah A. Nasser ,&nbsp;Ahmed I. El-Batal","doi":"10.1016/j.mycmed.2024.101489","DOIUrl":"10.1016/j.mycmed.2024.101489","url":null,"abstract":"<div><p>Dermatophytosis is a critical sort of skin infection caused by dermatophytes. The long-term treatment of such skin infections may be improved through the application of nanotechnology. This study aimed to prepare griseofulvin zinc Nanohybrid emulsion (GF-Zn–NHE) to improve griseofulvin activity against dermatophytes and some opportunistic pathogenic yeasts and bacteria. The GF-Zn-NHE is prepared by ultra-homogenization ultra-sonication strategies and validated by UV–visible spectroscopy analysis that confirms presences of griseofulvin and Zn-NPs peaks at 265 and 360 nm, respectively. The GF-Zn-NHE has mean distribution size 50 nm and zeta potential in the range from -40 to -36 mV with no significant changes in size distribution and particle size within 120 day ageing. Fourier transform infrared spectroscopy spectrum confirmed the presence of griseofulvin and Zn-NPs stretching vibration peaks. Gamma ray has a negative influence on GF-Zn-NE production and stability. GF-Zn-NHE drug release 95% up to 24 h and 98% up to 72 h of GF was observed and Zinc 90% up to 24 h and 95% up to 72 h, respectively. High antimicrobial activity was observed with GF-Zn–NHE against dermatophytic pathogens in compare with GF, GF-NE, zinc nitrate and ketoconazole with inhibition zone ranged from 14 to 36 mm. The results have shown that the MIC value for <em>Cryptococcus neoformans, Prophyromonas gingivalis</em> and <em>Pseudomonas aeruginosa</em> is 0.125 mg ml ⁻¹ and for <em>Trichophyton rubrum, L. bulgaricus</em> and <em>Escherichia coli</em> value is 0.25 mg ml ⁻¹ and for <em>Candida albicans, Malassezia furfur</em> and <em>Enterococcus faecalis</em> is 0.5 mg ml ⁻¹ and finally 1 mg ml ⁻¹ for <em>Streptococcus mutans</em>. TEM of treated <em>Cryptococcus neoformans</em> cells with GF-Zn-NHE displayed essentially modified morphology, degradation, damage of organelles, vacuoles and other structures.</p></div>","PeriodicalId":14824,"journal":{"name":"Journal de mycologie medicale","volume":"34 3","pages":"Article 101489"},"PeriodicalIF":2.2,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141397826","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cryptococcosis at the university hospital of Marseille: A case series","authors":"Ibrahim Dollo ,&nbsp;Estelle Menu ,&nbsp;Pierre Dudouet ,&nbsp;Camille Aubry ,&nbsp;Coralie L'Ollivier ,&nbsp;Stéphane Ranque","doi":"10.1016/j.mycmed.2024.101500","DOIUrl":"10.1016/j.mycmed.2024.101500","url":null,"abstract":"<div><p>Cryptococcosis is a fungal infection burdened by a high case-fatality rate in immunocompromised patients. Once limited to human immunodeficiency virus (HIV)-infected patients, the epidemiology of cryptococcosis has evolved in recent years and new risk factors have emerged. It is therefore essential to identify these risk factors in order to improve prevention and therapeutic efficacy. We conducted a retrospective observational study including all cases of cryptococcosis between January 2016 and December 2022, diagnosed at the University Hospital of Marseille. During the study period 15 cases of cryptococcosis were diagnosed. Six patients were HIV-infected. Nine patients had one or more comorbidities including liver cirrhosis, type 2 diabetes mellitus, primary immunodeficiency disorder, chronic lymphocytic leukemia and solid organ transplantation. Ten patients had central nervous system cryptococcosis, four had pulmonary cryptococcosis and one patient had extra-pulmonary disseminated cryptococcosis. Of the three patients with liver cirrhosis, two patients died with a post-mortem diagnosis. Our data suggest that emerging risk factors are probably underestimated by clinicians. It emphasizes the need for cryptococcal antigenemia as part of syndromic investigation of any unexplained fever or neurological symptoms in an at-risk patient. Early diagnosis and treatment are essential for patient's survival.</p></div>","PeriodicalId":14824,"journal":{"name":"Journal de mycologie medicale","volume":"34 3","pages":"Article 101500"},"PeriodicalIF":2.2,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S1156523324000416/pdfft?md5=10d9c247174ade6c70115a79888e49ac&pid=1-s2.0-S1156523324000416-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141636826","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Exploring the Co-occurrence of dermatophyte infection and ichthyosis: A report of 3 cases","authors":"Elisabetta Magnaterra,&nbsp;Elisa M. Difonzo,&nbsp;Manfredi Magliulo,&nbsp;Samantha F. Berti,&nbsp;Massimo Gola,&nbsp;Luigi Pisano","doi":"10.1016/j.mycmed.2024.101498","DOIUrl":"10.1016/j.mycmed.2024.101498","url":null,"abstract":"<div><p>Dermatophyte infections frequently pose diagnostic challenges, especially when occurring alongside ichthyosis, a genetic skin disorder characterized by dry, thickened, scaly skin. This case series outlines three cases where dermatophyte infections overlapped with ichthyosis, emphasizing the complexities in clinical identification and differential diagnosis. Atypical clinical presentations in these cases led to initial misdiagnoses. Ichthyosis, a genetic skin disorder characterized by thickened and scaly skin, creates an environment conducive to dermatophyte settlement, complicating the diagnostic process. The cases highlight the importance of considering fungal infections, even when clinical features deviate from the expected course. A vigilant diagnostic approach, including mycological examinations, is crucial for accurate identification and timely management.</p></div>","PeriodicalId":14824,"journal":{"name":"Journal de mycologie medicale","volume":"34 3","pages":"Article 101498"},"PeriodicalIF":2.2,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141579671","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Invasive candidiasis in dogs: A case report and review of the literature","authors":"Douglas M. Lorenzetti ,&nbsp;João P. Freitas ,&nbsp;Renata D. Mazaro ,&nbsp;Marina B. Beckenkamp ,&nbsp;Carla Weiblen ,&nbsp;Maria I. de Azevedo ,&nbsp;Laura B. Denardi ,&nbsp;Jânio M. Santurio ,&nbsp;Glaucia D. Kommers ,&nbsp;Alexandre A. Tonin ,&nbsp;Rafael A. Fighera","doi":"10.1016/j.mycmed.2024.101502","DOIUrl":"10.1016/j.mycmed.2024.101502","url":null,"abstract":"<div><p>Invasive candidiasis is characterized by the systemic dissemination of <em>Candida</em> spp. and colonization of multiple organs. We are reporting a case of invasive candidiasis in a 3.5-year-old female mixed-breed dog with a history of limb injury. After clinical evaluation and complementary examinations a sepsis diagnose was established. The patient remained hospitalized under antibiotic therapy, dying three days later. Necropsy revealed white, nodular (pyogranulomas), and multifocal areas on the liver, button ulcers in the stomach and intestines, and a random lung consolidation. Impression smears were made from the liver and lung surface lesions during necropsy showing yeast and pseudohyphae structures. Fragments of these organs were sent for fungal culture and subsequent molecular etiologic characterization, identifying it as <em>Candida albicans</em>. Histological examination of different organs showed pyogranulomatous inflammation surrounding the necrosis areas, which were full of yeast and pseudohyphae, as evidenced by periodic acid Schiff and immunohistochemistry. Neutropenia, as a consequence of sepsis, associated with the use of antibiotics may have allowed yeast invasion and proliferation in the mucosa of the gastrointestinal tract, reaching the liver and lungs through hematogenous route. Invasive candidiasis is a rare canine disease, and no other cases of neutropenia associated with antibiotic therapy, as a predisposing factors, have been reported.</p></div>","PeriodicalId":14824,"journal":{"name":"Journal de mycologie medicale","volume":"34 3","pages":"Article 101502"},"PeriodicalIF":2.2,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142021089","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Risk of fungal exposure in the homes of patients with hematologic malignancies","authors":"Marc Sautour ,&nbsp;Adrien Guilloteau ,&nbsp;Stéphane Valot ,&nbsp;Louise Basmaciyan ,&nbsp;Eloise Bailly ,&nbsp;Nathalie Sixt ,&nbsp;Jennifer Tetu ,&nbsp;Ingrid Lafon ,&nbsp;Denis Caillot ,&nbsp;Frédéric Dalle","doi":"10.1016/j.mycmed.2024.101492","DOIUrl":"https://doi.org/10.1016/j.mycmed.2024.101492","url":null,"abstract":"<div><h3>Background</h3><p>Patients with hematological malignancies are at a high risk of developing invasive fungal infections (IFI) because they undergo several cycles of treatment leading to episodes of neutropenia. In addition, they alternate between hospital stays and periods spent at home. Thus, when an IFI is diagnosed during their hospital stays, it is highly challenging to identify the origin of the fungal contamination. The objective of this study was to analyze at home fungal exposure of 20 patients with leukemia by taking air and water samples in their living residence.</p></div><div><h3>Methods</h3><p>Air was sampled in 3 rooms of each home with a portable air system impactor. Tap water was collected at 3 water distribution points of each home. For positive samples, fungi were identified by mass spectrometry or on the basis of their morphological features.</p></div><div><h3>Results</h3><p>85 % of homes revealed the presence in air of <em>Aspergillus</em> spp. and those belonging to the section <em>Fumigati</em> presented the highest concentrations and the greatest frequency of isolation. Concerning mucorales, <em>Rhizopus</em> spp. and <em>Mucor</em> spp. were isolated in air of 20 % and 5 % of dwellings, respectively. In 4 homes, more than 70 % of the fungal species identified in air were potential opportunists; these were mainly <em>Aspergillus</em> spp. with concentrations greater than 20 cfu/m³. The water samples revealed the presence of <em>Fusarium</em> in 3 dwellings, with concentrations up to 80 cfu/L. Finally, for one patient, fungal species isolated during a period of hospitalization were phenotypically similar to those isolated in samples taken at home. For a second patient, a PCR Mucorale was positive on a sample of bronchoalveolar fluid while air samples taken at his home also revealed also the presence of mucorales.</p></div><div><h3>Conclusion</h3><p>The presence of opportunistic fungal species in the air of all the explored homes suggests the need for strengthened preventive measures in the home of immunocompromised patients. It would be interesting to compare the fungi isolated (from patients and from their environment) by genotyping studies aimed at specifying the correspondence existing between fungal species present in the patients’ homes and those responsible for IFI in the same patients.</p></div>","PeriodicalId":14824,"journal":{"name":"Journal de mycologie medicale","volume":"34 3","pages":"Article 101492"},"PeriodicalIF":3.6,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141303827","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Current knowledge and practice of Candida auris screening in France: A nationwide survey from the French Society of Medical Mycology (SFMM)","authors":"J. Guitard ,&nbsp;A.P. Bellanger ,&nbsp;J. Dorin ,&nbsp;S. Cassaing ,&nbsp;A. Capitaine ,&nbsp;F. Gabriel ,&nbsp;M. Nicolas ,&nbsp;N. Coron ,&nbsp;P. Penn ,&nbsp;M. Moniot ,&nbsp;D. Quinio ,&nbsp;S. Ranque ,&nbsp;M. Sasso ,&nbsp;P. Lepape ,&nbsp;E. Dannaoui ,&nbsp;S. Brun ,&nbsp;C. Lacroix ,&nbsp;M. Cornu ,&nbsp;A. Debourgogne ,&nbsp;M.F. Durieux ,&nbsp;C. Hennequin","doi":"10.1016/j.mycmed.2024.101490","DOIUrl":"10.1016/j.mycmed.2024.101490","url":null,"abstract":"<div><p>Due to large outbreaks observed worldwide, <em>Candida auris</em> has emerged as a major threat to healthcare facilities. To prevent these phenomena, a systematic screening should be performed in patients transferred from regions where the pathogen is highly endemic. In this study, we recorded and analyzed French mycologists' current knowledge and practice regarding <em>C. auris</em> screening and diagnosis. Thirty-six centers answered an online questionnaire. Only 11 (30.6 %) participants were aware of any systematic screening for <em>C. auris</em> for patients admitted to their hospital. In the case of post-admission screening, axillae/groins (<em>n</em> = 21), nares (<em>n</em> = 7), rectum (<em>n</em> = 9), and mouth (<em>n</em> = 6) alone or various combinations were the body sites the most frequently sampled. Only six centers (8.3 %) reported using a commercially available plate allowing the differentiation of <em>C. auris</em> colonies from that of other <em>Candida</em> species, while five laboratories (13.8 %) had implemented a <em>C. auris</em>-specific qPCR. Considering the potential impact on infected patients and the risk of disorganization in the care of patients, it is crucial to remember to biologists and clinicians the utmost importance of systematic screening on admission.</p></div>","PeriodicalId":14824,"journal":{"name":"Journal de mycologie medicale","volume":"34 3","pages":"Article 101490"},"PeriodicalIF":3.6,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S1156523324000313/pdfft?md5=d88548f9fdef058f33432155b4636f75&pid=1-s2.0-S1156523324000313-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141277506","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Natural disasters and the rise of zoonotic diseases: A case of post-earthquake disseminated cryptococcosis in a dog","authors":"Ezgi Sababoglu Baytaroglu ,&nbsp;Volkan Ipek ,&nbsp;Halil Ibrahim Gokce ,&nbsp;Leyla Elif Ozgu Ayozger ,&nbsp;Berkay Olguner","doi":"10.1016/j.mycmed.2024.101501","DOIUrl":"10.1016/j.mycmed.2024.101501","url":null,"abstract":"<div><p>Cryptococcosis is a systemic zoonotic disease that is challenging to diagnose based on clinical findings in cats and dogs due to the nonspecific nature of its clinical presentation. This case report aims to document the first confirmed case of disseminated cryptococcosis caused by <em>Cryptococcus neoformans</em> in a dog in Turkey and to highlight the potential link between natural disasters such as earthquakes and the emergence of zoonotic diseases in domestic animals. A two-and-a-half-year-old spayed female Cocker Spaniel presented with increased respiratory sounds, skin lesions, facial swelling and enlarged lymph nodes. These symptoms appear to be a complication of <em>Demodex</em> infestation due to the stress experienced by the dog following exposure to a severe earthquake. Diagnostic procedures including cytologic examination, fungal culture and DNA sequence analysis, which confirmed the infection was caused by <em>C. neoformans</em>. Due to the delay in the correct diagnosis of the disease, which, contrary to common data, started as an allergic reaction on the skin and was later diagnosed as a <em>Demodex</em> infestation, the dog died of severe respiratory failure during the treatment with itraconazole. The case highlights the critical role of veterinary emergency and critical care in the diagnosis and management of zoonotic diseases post-natural disasters. It also highlights the need for increased awareness and preparedness among veterinary professionals to address animal health challenges following such events.</p></div>","PeriodicalId":14824,"journal":{"name":"Journal de mycologie medicale","volume":"34 3","pages":"Article 101501"},"PeriodicalIF":2.2,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141878701","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The mycobiome affects viral susceptibility of skin epithelium","authors":"Liam F. Peterson ,&nbsp;Lisa A. Beck ,&nbsp;Matthew G. Brewer","doi":"10.1016/j.mycmed.2024.101499","DOIUrl":"10.1016/j.mycmed.2024.101499","url":null,"abstract":"","PeriodicalId":14824,"journal":{"name":"Journal de mycologie medicale","volume":"34 3","pages":"Article 101499"},"PeriodicalIF":2.2,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141636827","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}