{"title":"Eye muscle nerves nuclear size in a breed of domestic rabbits with floppy ears.","authors":"G Rehkämper, H D Frahm, M Dion","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>In many wild species there is a correlation between the capacity for directional hearing and directional seeing, which is associated with the mobility of the eye balls. Among the breeds of domestic rabbits, there are some with pendulous, floppy external ears (e.g., Englische Widder, EW) that might limit directional hearing. The size of the brain stem nuclei in EWs has been determined and compared to rabbits with upright ears. In EW, the oculomotor nuclei are relatively larger than in the other breeds. Possibly, this indicates a compensation of a loss in directional hearing ability achieved through greater mobility of the eyes. At the same time, a variability of brain composition between the breeds, which is an intraspecific variability, is obvious.</p>","PeriodicalId":14790,"journal":{"name":"Journal fur Hirnforschung","volume":"39 3","pages":"401-8"},"PeriodicalIF":0.0,"publicationDate":"1999-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"21397909","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Axon collaterals projection from nucleus reticularis tegmenti pontis onto the cerebellar paramedian lobule in the rabbit: a fluorescent double labelling study.","authors":"B Mierzejewska-Krzyzowska","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Double labelling method with retrograde transport of fluorescent tracers (Fast Blue; FB and Diamidino Yellow; DY) was employed in the rabbit to investigate whether neurones of the nucleus reticularis tegmenti pontis (NRTP) give off axon collaterals to the cerebellar paramedian lobule (PML) of both sides. Following injections to various regions of the homotopic or heterotopic sublobules of the left (FB) and right (DY) PML cortex, distribution of double labelled neurones within NRTP was analyzed. NRTP of the rabbit consists of a medial principal part (the nucleus papillioformis: PLF) and smaller lateral part (the processus tegmentosus lateralis: PTL). Within PLF three subdivisions are to be distinguished: the dorsomedial part -- zone A, the main part -- zone B and the ventrolateral part -- zone C. The present study in the rabbit indicated collateral projections from neurones in some NRTP regions to the both PML. The cells of origin of these projections were located prominently through the rostrocaudal extent of zone B. Projections from zone A were sparse and those from zone C were absent. Moreover, a weak projection arose mainly from the caudal aspect of PTL. It is concluded that the rostral (e and f) and middle (c and d) sublobules are the main targets for the NRTP-PML branching projections.</p>","PeriodicalId":14790,"journal":{"name":"Journal fur Hirnforschung","volume":"39 3","pages":"321-33"},"PeriodicalIF":0.0,"publicationDate":"1999-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"21397981","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"PCNA positivity in the telencephalic matrix areas in the adult of a newt, Triturus carnifex.","authors":"V Margotta, A Morelli, L Alfei","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The Proliferating Cell Nuclear Antigen (PCNA) is an auxiliary protein of the DNA polymerase delta, belonging to the cyclin family, which attains appreciable levels only in those phases of the cell cycle in which DNA synthesis occurs. Using an immunocytochemical method that exploits this proliferative marker, we observed a certain PCNA positivity in the telencephalon of normal adult individuals of Triturus carnifex. The elements that display this peculiarity occupy an ependymal and/or sub-ependymal site. They are located in the anterior portion of the telencephalon only at the dorsal level and tend to decrease in number until they disappear temporarily as the intermediate portion is approached. In the posterior portion of the telencephalon, the dorsal labelling patterns, the size of which is however smaller than that observed more anteriorly, reappear and in the ventral region a large population of labelled cells appears. Then, again proceeding in a caudal direction, while the PCNA-positive elements lying dorsally diminish and disappear, they persist in the ventral region and gradually taper off until they final disappear where the telencephalic ventricles come together. This immunocytochemical picture supports the findings of other authors in adult Urodeles under both normal and experimental conditions (with classical and autoradiographic histological techniques) concerning the persistence of the telencephalon in dorsal and ventral germinative areas responsible for physiological and plastic neurogenetic events.</p>","PeriodicalId":14790,"journal":{"name":"Journal fur Hirnforschung","volume":"39 4","pages":"525-30"},"PeriodicalIF":0.0,"publicationDate":"1999-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"21686998","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
J M De Gandarias, P L Mendez, L Vegas, E Echevarría, J L Maza, L Casis
{"title":"Infraorbital nerve transection increases NADPH-diaphorase activity in the rat mesencephalic trigeminal nucleus.","authors":"J M De Gandarias, P L Mendez, L Vegas, E Echevarría, J L Maza, L Casis","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Complete information concerning possible alterations in nitric oxide production in the rat brainstem trigeminal system after peripheral nerve lesion is still lacking. This being the case, density of NADPH-diaphorase positive neurons in the trigeminal mesencephalic nucleus after experimental infraorbital nerve transection was studied. In the lesioned side, an ipsilateral increase in NADPH-d positive neurons was found at postoperative days 4 and 6 with respect to contralateral, without changes after a 2 months period. These data suggest that nitric oxide could be involved in regeneration of afferent fibers concerned with the periodontal receptors of maxillary teeth.</p>","PeriodicalId":14790,"journal":{"name":"Journal fur Hirnforschung","volume":"39 4","pages":"567-71"},"PeriodicalIF":0.0,"publicationDate":"1999-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"21686231","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Cell-cell coupling in cultures of striatal and cortical astrocytes of the monkey Cebus apella.","authors":"S Gayol, T Pannicke, A Reichenbach, J A Colombo","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Astrocytes were cultured from striatum and neocortex of fetal (embryonic day 90) monkeys (Cebus apella). The cultures grew well, and the cells retained viability after freeze-storage and thawing. The cells displayed depolarized membrane potentials (-19 and -33 mV, for striatal and cortical cells, respectively) and the vast majority of cells were dye-coupled to a mean of 7 (1-18) neighbouring cells. Cell coupling was blocked by octanol (0.25 and 0.5 mM) but was independent of high K+ (10 and 50 mM) and glutamate (500 microm). Thus, cultures of fetal primate astrocytic cells are established as a model system for studies on astroglial cell-cell coupling.</p>","PeriodicalId":14790,"journal":{"name":"Journal fur Hirnforschung","volume":"39 4","pages":"473-9"},"PeriodicalIF":0.0,"publicationDate":"1999-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"21686407","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The pigmentarchitectonic divisions and neuronal types of the central nucleus and intercalated masses of the human amygdala.","authors":"S Urban, D M Yilmazer-Hanke","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The central nucleus of the amygdala is a high level limbic center which controls vegetative functions and is involved in neurodegenerative diseases. In the present study, the central nucleus and intercalated masses of the human amygdala have been investigated with the pigment Nissl technique. The central nucleus of the amygdala consists of a main body surrounded by fiber tracts and accessory islands located dorsal to the main body. In the main body, one can distinguish the medial central nucleus with heavily pigmented neuronal types and the lateral central nucleus, which is composed of three subnuclei: the centro-lateral central nucleus has heavily and sparsely pigmented neuronal types, the apico-lateral central nucleus sparsely pigmented neuronal types and the capsular-lateral central nucleus heavily pigmented neuronal types. Based on the pigmentarchitecture, the accessory islands of the central nucleus are part of the apico-lateral and capsular-lateral central nuclei. Altogether, there are eight neuronal types in the medial central nucleus, while four to six neuronal types are found in the subnuclei of the lateral central nucleus. In the intercalated masses, there are four neuronal types, and the predominating cell types are small and sparsely pigmented. In conclusion, the pigment Nissl stain shows that the lateral central nucleus of the human amygdala has three subnuclei, and the accessory islands are part of two of these subnuclei. Furthermore, numerous neuronal types are identified within the central nucleus and intercalated masses of the amygdala, which may reflect the variability in their neurochemical characteristics.</p>","PeriodicalId":14790,"journal":{"name":"Journal fur Hirnforschung","volume":"39 3","pages":"311-9"},"PeriodicalIF":0.0,"publicationDate":"1999-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"21397980","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Establishment of the FMRFamide-immunoreactive olfacto-retinalis pathway during ontogeny of the rainbow trout (Oncorhynchus mykiss).","authors":"C R Malz, U Kindermann","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Migration of neurons is one of the mechanisms establishing normal central nervous system connectivity during ontogeny. Proper timing of axonal sprouting is relevant in the same context. In the present study, we used the immunoreactivity of the tetrapeptide FMRFamide (Phe-Met-Arg-Phe-NH2) to visualize the olfacto-retinalis projection during trout ontogeny. It starts to innervate the retina two to four weeks after hatching, in contrast to reports on salmon where it only appears after the fish are imprinted on their natal stream.</p>","PeriodicalId":14790,"journal":{"name":"Journal fur Hirnforschung","volume":"39 3","pages":"349-53"},"PeriodicalIF":0.0,"publicationDate":"1999-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"21397983","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Substance P receptor-like immunoreactive neurons in the caudal spinal trigeminal nucleus send axons to the gelatinosus thalamic nucleus in the rat.","authors":"Y Q Li","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>By means of substance P receptor (SPR) immunofluorescence histochemistry combined with Fluoro-Gold (FG) fluorescent retrograde labeling, SPR-like immunoreactive neurons in the caudal spinal trigeminal nucleus of the rat were observed to send their axons to the gelatinosus thalamic nucleus with a clear ipsilateral dominance. FG/SPR double-labeled neurons were distributed mainly in the ventral part of lamina I at the rostral level of the caudal spinal trigeminal nucleus. The percentages of FG/SPR-LI neurons in the total number of SPR-LI neurons and FG-labeled neurons are 10.5% and 31.1%, respectively. The present results suggest that trigemino-gelatinosus thalamic projection neurons with SPR-LI in the caudal spinal trigeminal nucleus might receive SP-containing, nociceptive primary afferent fibers from the orofacial region and transmit nociception to the gelatinosus thalamic nucleus.</p>","PeriodicalId":14790,"journal":{"name":"Journal fur Hirnforschung","volume":"39 3","pages":"277-82"},"PeriodicalIF":0.0,"publicationDate":"1999-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"21397469","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A light and electron microscopic study of GAT-1 positive cells in the monkey brainstem and spinal cord.","authors":"C H Ng, W Y Ong","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The distribution of the GABA transporter GAT-1 was studied in the monkey brainstem and spinal cord, using an affinity purified polyclonal antibody against a synthetic peptide corresponding to the C terminus of GAT-1. Very dense staining was observed in the interpeduncular nucleus, the inferior olivary nucleus and the substantia gelatinosa of the spinal cord, whilst dense labelling was observed in the substantia nigra, cochlear nuclei, vestibular nuclei, the spinal nucleus of V, the area postrema and the ventral horn of the spinal cord. Electron microscopy showed that the labelled profiles consisted of axon terminals that formed symmetrical synapses, consistent with GABAergic terminals. Many of the nuclei that were densely labelled for GAT-1 were those that received primary auditory, vestibular, or somatosensory inputs and the high density of GAT-1 in these nuclei suggests that GAT-1 plays an important role in terminating the inhibitory effects of GABA, at these nuclei.</p>","PeriodicalId":14790,"journal":{"name":"Journal fur Hirnforschung","volume":"39 4","pages":"551-7"},"PeriodicalIF":0.0,"publicationDate":"1999-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"21687001","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Small brain, large brain -- a quest for nature's scale-up rules.","authors":"J Prothero","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>A scaling model of the gyrencephalic mammalian brain, invoking identical repeating cortical units, whose number and size both increase with increasing brain size, was described previously (Prothero, 1997a,b). Each repeating unit, of microscopic dimensions, is viewed as extending from the pial membrane to the underlying white matter. The model predicts discrete scaling exponents, all integral multiples of 1/9, as a function of brain size, as follows: cortical thickness (1/9), outer cortical surface area (6/9), total (folded) cortical surface area (8/9), cortical volume (9/9), white matter volume (9/9), neuron line-count (0/9) and neuron volume density (-3/9). In the present paper extensions to the model give discrete exponents for the scaling of the cross-sectional area of the corpus callosum (6/9), for mean foliar and gyral width (each 1/9), for foliar number (2/9), for mean foliar length (3/9), for mean foliar and gyral perimeter (each 3/9) and for total foliar and total gyral length (each 5/9). The predicted scaling exponent for cross-sectional area of the corpus callosum is in reasonable agreement with the empirical observations. Needed are more precise and more extensive data on cortical folding to stringently test the model predictions relating to cortical folding. On the whole, the model is in good agreement with a diverse body of empirical data bearing on the scaling of the gyrencephalic mammalian brain.</p>","PeriodicalId":14790,"journal":{"name":"Journal fur Hirnforschung","volume":"39 3","pages":"335-47"},"PeriodicalIF":0.0,"publicationDate":"1999-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"21397982","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}