Journal fur Hirnforschung最新文献

The central distribution pattern of primary afferent fibers innervating the thigh muscle posterior iliotibialis in the chicken. 支配鸡大腿肌髂胫后肌的初级传入纤维的中心分布模式。

Journal fur Hirnforschung Pub Date : 1999-01-01

T Maeshima, R Ito, M Matsukawa, M Usuba, N Okado

引用次数: 0

Neuronal organization of the optic tectum in the river lamprey, Lampetra japonica: a Golgi study. 江七鳃鳗视顶盖的神经元组织:高尔基研究。

Journal fur Hirnforschung Pub Date : 1999-01-01

N Iwahori, T Kawawaki, J Baba

{"title":"Neuronal organization of the optic tectum in the river lamprey, Lampetra japonica: a Golgi study.","authors":"N Iwahori, T Kawawaki, J Baba","doi":"","DOIUrl":"","url":null,"abstract":"The neuronal and laminar organization of the optic tectum (OT) in the river lamprey was studied using the rapid Golgi method. Based primarily on the distribution pattern of the dendrites, the OT neurons were divided into vertical, horizontal and stellate neurons. The river lamprey OT shows a laminar structure consisting of eight concentric strata. The stratum ependymale consists of several rows of ependymal cells. The stratum cellulare periventriculare contains one to two rows of vertical neurons. The stratum fibrosum periventriculare is thin and contains a few vertical neurons. The stratum cellulare et fibrosum internum consists of several alternating cellular and fibrous layers: a large variety of vertical and horizontal neurons are distributed in this stratum. The stratum fibrosum centrale consists of compact horizontal fiber bundles, among which a few horizontal neurons are disseminated. In the stratum cellulare et fibrosum externum, numerous fibers run horizontally in a loosely organized plexus; various types of vertical, horizontal and stellate neurons are distributed among these fibers. The stratum opticum is the main terminal area of the optic nerve, and contains stellate and horizontal neurons. The stratum marginale is a thin layer and consists of sparse populations of vertical and horizontal neurons. Besides the above outer to inner laminar structure, the OT is divided into medial (m-OT) and lateral parts (1-OT), based primarily on the distribution pattern of the dendrites. The dendrites of neurons in the m-OT are distributed almost exclusively within the OT. On the other hand, the dendrites of some neurons in the 1-OT extended into the confines of the torus semicircularis (TS), and conversely, the dendrites of some neurons in the TS are distributed in the 1-OT. These findings are discussed in relation to the neuronal and laminar organization of the OT in other lamprey species and to recent hodological studies.","PeriodicalId":14790,"journal":{"name":"Journal fur Hirnforschung","volume":"39 3","pages":"409-24"},"PeriodicalIF":0.0,"publicationDate":"1999-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"21397910","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Electron microscopic studies on NO-synthase activity in brain phagocytes of rat cerebral cortex after ischemic and traumatic brain injury. 脑缺血和脑外伤后大鼠大脑皮层吞噬细胞no合酶活性的电镜研究。

Journal fur Hirnforschung Pub Date : 1999-01-01

M Walski, B Gajkowska

{"title":"Electron microscopic studies on NO-synthase activity in brain phagocytes of rat cerebral cortex after ischemic and traumatic brain injury.","authors":"M Walski, B Gajkowska","doi":"","DOIUrl":"","url":null,"abstract":"In the present study we used a cytochemical method for electron microscopy for nitric oxide synthase (NOS) detection in rat cerebral cortex. The animals were subjected to total brain ischemia and mechanical trauma. Tissue was fixed in 3% paraformaldehyde and 0.5% glutaraldehyde which enabled excellent preservation of cellular ultrastructure and resulted in an increase in method reproducibility. The results show the distribution of the particles reflecting the sites of NOS activity in the capillaries and other, more distant locations. NOS activity was found in thrombocytes, endothelium and pericytes. Moreover, the morphologically differentiated perivascular phagocytes demonstrated NOS reaction product in their cytoplasm. These phagocytes containing polymorphic phagolysosomes, surrounded the fragments of damaged neurons. We propose that these cells are descendants of blood-borne monocytes and transformed pericytes. In the areas distant to the sites of injury we noticed cells showing ultrastructural features of activated microglia. These cells were in a close contact with neural perikarya and contained iNOS-specific reaction product in the cytoplasm. In conclusion, our studies revealed differentiated forms of brain phagocytes, the occurrence of which depended on the type of cerebral injury. These cells demonstrated NOS reaction product suggesting their role in cerebral NO production during ischemia and other forms of brain injury.","PeriodicalId":14790,"journal":{"name":"Journal fur Hirnforschung","volume":"39 4","pages":"455-63"},"PeriodicalIF":0.0,"publicationDate":"1999-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"21686405","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Benzodiazepine binding sites in the human hypothalamus. Autoradiographic study. 人类下丘脑中苯二氮卓类药物的结合位点。Autoradiographic研究。

Journal fur Hirnforschung Pub Date : 1999-01-01

M Najimi, M Bennis, F Chigr, N Kopp, E Moyse, S Miachon

{"title":"Benzodiazepine binding sites in the human hypothalamus. Autoradiographic study.","authors":"M Najimi, M Bennis, F Chigr, N Kopp, E Moyse, S Miachon","doi":"","DOIUrl":"","url":null,"abstract":"Using in vitro labelling and autoradiographic techniques, we have analyzed the fine and the detailed distribution of benzodiazepine binding sites in the post-mortem human hypothalamus. Binding sites were labelled in mounted tissue sections from adult brains, using the selective high affinity ligand [3H]-Flunitrazepam. A heterogeneous distribution of benzodiazepine binding sites was found throughout the rostrocaudal extent of human hypothalamus. The autoradiographic labelling was shown in the three hypothalamic parts, i.e., anterior, mediobasal and posterior levels. At the anterior level, the highest densities were present in the diagonal band of Broca, the preoptic area (medial and lateral parts) and the septohypothalamic nucleus. At the mediobasal hypothalamic level, the highest densities were mainly localized in the ventromedial nucleus, whereas the other structures were moderately labelled with [3H]-Flunitrazepam. The mammillary complex as well as the posterior hypothalamic area represented the most heavily labelled structures in the posterior hypothalamus. The results obtained in this study, indicate the presence of a large and heterogeneous distribution of benzodiazepine binding sites in human adult hypothalamus. This could support their implication in the control of distinct neural functions (like neuroendocrine role).","PeriodicalId":14790,"journal":{"name":"Journal fur Hirnforschung","volume":"39 4","pages":"493-502"},"PeriodicalIF":0.0,"publicationDate":"1999-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"21686995","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Ultrastructural changes in the atrioventricular valves of streptozotocin-induced diabetic rats. 链脲佐菌素诱导的糖尿病大鼠房室瓣膜超微结构变化。

Journal fur Hirnforschung Pub Date : 1999-01-01

S D Kumar, S S Tay

{"title":"Ultrastructural changes in the atrioventricular valves of streptozotocin-induced diabetic rats.","authors":"S D Kumar, S S Tay","doi":"","DOIUrl":"","url":null,"abstract":"The present study describes ultrastructural changes in the atrioventricular (AV) valves of diabetic rats at 3, 6, 9 and 12 months. At 3 and 6 months of diabetes, the interstitial cells were characterized by an accumulation of vacuoles, lysosomes, electron-dense vesicles, mitochondria and cisternae of rough endoplasmic reticulum in the cytoplasm. There were numerous collagen fibres in the interstitial space. Unmyelinated axons were ensheathed by Schwann cells. Infiltration of macrophages was observed near the interstitial cells. Each macrophage showed a large round or oval nucleus containing heterochromatin masses at the periphery of the cell nucleus. At 9 and 12 months of diabetes, the interstitial cells contained numerous vacuoles, dilated mitochondria, agranular vesicles and a prominent multivesicular body in the cytoplasm. Degenerating unmyelinated nerve fibres were encountered near the interstitial cells. Phagocytic macrophages contained numerous vacuoles of various sizes, which occupied most of the cytoplasmic area. Several vacuoles and degenerated electron-dense granules (some of them appeared to be fragmented) were present in the cytoplasm of interstitial cells and macrophages. It is concluded that interstitial cells in the AV valves contribute to valvular dysfunction in the streptozotocin-induced diabetic rats.","PeriodicalId":14790,"journal":{"name":"Journal fur Hirnforschung","volume":"39 4","pages":"559-66"},"PeriodicalIF":0.0,"publicationDate":"1999-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"21687002","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Localization of Barrington's nucleus in the pontine dorsolateral tegmentum of the rabbit. 兔脑桥背外侧被盖巴林顿核的定位。

Journal fur Hirnforschung Pub Date : 1999-01-01

Y Q Ding, H X Zheng, D S Wang, B Z Lu, J Q Xu

{"title":"Localization of Barrington's nucleus in the pontine dorsolateral tegmentum of the rabbit.","authors":"Y Q Ding, H X Zheng, D S Wang, B Z Lu, J Q Xu","doi":"","DOIUrl":"","url":null,"abstract":"The localization of Barrington's nucleus in the dorsolateral pons of the rabbit and its projections to the sacral spinal cord were examined by using retrograde and anterograde labeling methods combined with immunohistochemistry. After injection of wheat germ agglutinin-horseradish peroxidase (WGA-HRP) or a fluorescence tracer, tetramethylrhodamine-dextran amine (TMR), into the sacral spinal cord segments, a cluster of neurons labeled with WGA-HRP or TMR were seen in the pontine dorsolateral tegmentum. To identify whether the retrogradely labeled neurons were situated within the locus coeruleus, the sections containing TMR-labeled neurons through the pons were incubated with anti-tyrosine hydroxylase (TH) antibody and observed under epifluorescence microscope. It was shown that the cluster of TMR-labeled neurons in the dorsolateral tegmentum were surrounded by TH-positive neurons, but they were negatively immunostained with TH-like immunoreactivity. In anterograde experiment, injection of WGA-HRP into the dorsolateral tegmentum resulted in many anterogradely labeled nerve fibers and terminals in the sacral spinal cord, including the sacral parasympathetic nucleus. The present results suggest that the cluster of neurons in the dorsolateral tegmentum of the rabbit may correspond to Barrington's nucleus revealed in the rat and cat, and thus may be involved in micturtion reflex of the rabbit.","PeriodicalId":14790,"journal":{"name":"Journal fur Hirnforschung","volume":"39 3","pages":"375-81"},"PeriodicalIF":0.0,"publicationDate":"1999-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"21397906","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Distribution of cytoplasmic phospholipase A2 in the normal rat brain. 正常大鼠脑内胞质磷脂酶A2的分布。

Journal fur Hirnforschung Pub Date : 1999-01-01

W Y Ong, T L Sandhya, L A Horrocks, A A Farooqui

引用次数: 0

Disruption of patterns of immunoreactive glial fibrillary acidic protein processes in the Cebus Apella striate cortex following loss of visual input. 视觉输入丧失后无脑纹状皮层免疫反应性胶质原纤维酸性蛋白过程模式的破坏。

Journal fur Hirnforschung Pub Date : 1999-01-01

J A Colombo, A Yáñez, S Lipina

引用次数: 0

Lectin binding sites in the vomeronasal organ and the olfactory epithelium of the tree shrew tupaia belangeri. 树鼩犁鼻器官和嗅上皮中凝集素结合位点的研究。

Journal fur Hirnforschung Pub Date : 1999-01-01

C R Malz, P Schwartz, H J Kuhn

{"title":"Lectin binding sites in the vomeronasal organ and the olfactory epithelium of the tree shrew tupaia belangeri.","authors":"C R Malz, P Schwartz, H J Kuhn","doi":"","DOIUrl":"","url":null,"abstract":"Lectin binding histochemistry was performed on the peripheral parts of the vomeronasal and olfactory system of Tupaia belangeri to investigate the distribution and density of defined carbohydrate terminals on the cell surface glycoproteins of the specific receptors, nerves and associated glands. Dolichus biflorus lectin staining was identifiable in all cells of the sensory epithelia of both systems, with the exception of the olfactory basal cells. The vomeronasal nerve expressed alpha-N-acetylgalactosamine, the olfactory nerve did not. Differences in the Dolichus biflorus lectin staining pattern were noted in the sensory and the non-sensory epithelium of the vomeronasal organ of pregnant and non-pregnant Tupaia belangeri. Like in other mammals examined so far, the systems were characterized by a moderate to high alpha-fucose density, only the supporting cells of the olfactory epithelium remaining unstained by Ulex europaeus I lectin. Bandeiraea simplicifolia II lectin binding was moderate in the olfactory glands and the brush border. In the vomeronasal organ, sugar residues of alpha- and beta-N-acetyl-D-glucosamine were found selectively in the transition zone between the two vomeronasal epithelia, where regeneration should take place. We tentatively conclude that specific glycoproteins, whose terminal sugars were detected by lectin binding, might be related to the chemoreception and transduction of the olfactory/pheromonal message into a nervous signal or to the histogenesis of the olfactory/vomeronasal system. This study showed that beside the species, pregnancy might play a role in these processes in the vomeronasal organ.","PeriodicalId":14790,"journal":{"name":"Journal fur Hirnforschung","volume":"39 4","pages":"481-7"},"PeriodicalIF":0.0,"publicationDate":"1999-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"21686408","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

NADPH-diaphorase expression in the hypothalamo-hypophysial system of different catfish. 不同种类鲶鱼下丘脑-垂体系统nadph - diaphase的表达。

Journal fur Hirnforschung Pub Date : 1999-01-01

A G Jadhao, I Wilke, D L Meyer

引用次数: 0