Gynecology & Reproductive Health最新文献

{"title":"Oil-Based Hysterosalpingography ?mproves Leukaemia ?nhibitory Factor Expression ?n Endometrial Flushing Samples","authors":"N. Gungor, A. Yurci, Ş. Hatırnaz, K. Cil, Oğuz Güler","doi":"10.33425/2639-9342.1204","DOIUrl":"https://doi.org/10.33425/2639-9342.1204","url":null,"abstract":"Objective: The biological mechanism of the fertility-enhancing effect of hysterosalpingography (HSG) is not fully known. Leukemia inhibitory factor (LIF) is an important cytokine involved in implantation. This study was planned to investigate the effect of HSG on LIF mRNA expression in endometrial flushing samples. Methods: Forty infertile patients scheduled for HSG were included in the study. Before HSG, endometrial flushing was performed in the mid-luteal phase, followed by contrast-medium infusion into the cavity. Second flushing was done in the mid-luteal phase of the next cycle. Ten patients who underwent diagnostic hysteroscopy were taken as the second control group. LIF mRNA levels were measured by RT-PCR in endometrial flushing samples collected from each group. Results: The pre-HSG LIF mRNA levels of the infertile group were significantly lower than those of the fertile group. In infertile patients, LIF mRNA expression increased 3.2 times after HSG compared to baseline levels. LIF values reached fertile levels after HSG. While the LIF levels measured in the hysteroscopy group were significantly lower than in fertile patients, they were similar to the pre-HSG values of infertile patients. LIF levels of infertile patients after HSG were found to be significantly higher than those of the hysteroscopy group. Conclusions: In infertile patients, HSG contributes to receptivity by increasing LIF mRNA synthesis.","PeriodicalId":147903,"journal":{"name":"Gynecology & Reproductive Health","volume":"4 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132945011","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Postpartum Contraception within the Gynecology and Obstetrics Department of Teaching Hospital Sanou Sourô in Bobo-Dioulasso (Burkina Faso)","authors":"Bambara Moussa, I. Ouédraogo, K. Evélyne, Zabre Patenema","doi":"10.33425/2639-9342.1207","DOIUrl":"https://doi.org/10.33425/2639-9342.1207","url":null,"abstract":"Introduction Postpartum family planning enables people to have the desired number of children and to determine birth spacing, which consists in using numerous, and effective contraceptive methods [1]. According to Cleland [2], family planning can prevent more than 30% of maternal deaths and 10% of child deaths if couples allow more than two years to elapse between pregnancies. Within the World Health Organization, it is now recognized that the immediate postpartum period constitutes an opportunity to boost postpartum family planning [1].","PeriodicalId":147903,"journal":{"name":"Gynecology & Reproductive Health","volume":"60 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123450519","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Postpartum Acute Intestinal Intussusception: A Case Report with Literature Review of a “Pediatric Pathology in an Adult”","authors":"Christella Iroume, L. Makowa, Christiale Batibonak, Gouag G, Sonia Zebaze, Kaptue Ginette, Kamsu Zicfried, B. Jemea","doi":"10.33425/2639-9342.1198","DOIUrl":"https://doi.org/10.33425/2639-9342.1198","url":null,"abstract":"Introduction: Intestinal intussusception is defined as the penetration of a proximal segment of the intestine into a distal segment, leading to intestinal obstruction. It is a common cause of small bowel obstruction in children. This pathology is rare in adults and represents only 1% of all cases of intestinal obstruction. We report a case of ileoileal intestinal intussusception in a 26-years-old adult woman, complicating postpartum eclampsia. Case Presentation: This was a 26-years patient being treated for eclampsia associated with HELLP syndrome and complicated with acute kidney injury. The diagnosis of intussusception was made based on a clinical bowel obstruction syndrome and confirmed with ultrasounography. The management consisted of laparotomy with surgical resection of the invaginated bowel segment. Conclusion: Intestinal intussusception is mainly a childhood pathology which may exceptionally occur in adults. The degree of bowel and hence abdominal distension caused by intestinal obstruction justifies surgical exploration, with subsequent resection of invaginated segment as a therapeutic intervention.","PeriodicalId":147903,"journal":{"name":"Gynecology & Reproductive Health","volume":"5 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-10-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128395251","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Fibroids and Infertility: Transabdominal Ultrasound Guided Oocyte Retrieval in Patient with Massive Multiple Leiomyomas - Case Report","authors":"Culej Diana, Bursac Danijel, Pavan Jukic Doroteja, Planinic Rados Gordana, Valetić Josip, D. Zeljko","doi":"10.33425/2639-9342.1199","DOIUrl":"https://doi.org/10.33425/2639-9342.1199","url":null,"abstract":"The World Health Organization (WHO) defines infertility as a disease characterized by the absence of pregnancy after 12 or more months of regular unprotected sex. Couple infertility is an increasingly present problem in today’s society. We present a case of a patient with assisted reproduction program complicated with uterus altered by numerous fibroids who obstructed routine transvaginal oocyte retrival. Routine transvaginal procedure of oocyte retrival was impossible due to the size and shape of the uterus altered by numerous fibroids. The aspiration was done by transabdominal ultrasound-guided follicular aspiration. A successful embryo transfer was performed without complications. Patient was successfully delivered at 32 weeks of gestation. Main objective of this case report is to bring to the light the challenging situations that infertility specialist face, and alternative solutions that deviate from the daily routine but bring the final desired result – birth of the healthy newborn.","PeriodicalId":147903,"journal":{"name":"Gynecology & Reproductive Health","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-10-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130702129","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Enigma in the Prediction of Pre-Eclampsia and the Relevance in Management","authors":"R. Vijayan, Ramesh Pundi, A. Alvarez, S. Bhandari, M. A. Diaz","doi":"10.33425/2639-9342.1201","DOIUrl":"https://doi.org/10.33425/2639-9342.1201","url":null,"abstract":"The ultrasonographic markers are less sensitive and that the biochemical markers are not very beneficial. Various serum markers have been investigated as probable predictors in the first and second trimester of pregnancy. The markers utilized are both angiogenic and anti-angiogenic factors and related to the placentation. Appropriate screening for early-onset pre-eclampsia is reasonable in the first trimester of pregnancy with a high detection rate and a low false-positive rate. Furthermore, the biochemical markers are not very beneficial when used alone as a predictive tool of pre-eclampsia. A combination of the biochemical markers along with maternal history, clinical features, risk factors, demographic characteristics, Doppler velocimetry could be more effective in the prediction of pre-eclampsia. Besides, an antenatal check-up at 11-13 weeks when maternal risk factors and history is cumulatively assessed along with biophysical and biochemical parameters has been suggested by recent approaches. Capsule A combination of the biochemical markers and maternal history, clinical features, risk factors, demographic characteristics, and Doppler velocimetry could be more effective in predicting pre-eclampsia.","PeriodicalId":147903,"journal":{"name":"Gynecology & Reproductive Health","volume":"115 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-10-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126989204","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Serum Anti-Mullerian Hormone (AMH) Levels are Effective in Predicting the Diagnosis of Four Polycystic Ovarian Syndrome (PCOS) Phenotypes","authors":"Justin Armstrong, Christina Cortes, K. Hawkins, A. Younis","doi":"10.33425/2639-9342.1203","DOIUrl":"https://doi.org/10.33425/2639-9342.1203","url":null,"abstract":"Purpose: Women with PCOS have higher levels of AMH than matched controls; however, the feasibility of using elevated serum AMH value as a criterion, in the diagnosis of PCOS, is still debatable. The goal of this study was to examine a population of women with elevated AMH (>5.0 ng/mL) and evaluate whether high serum AMH value can be predictive of four different clinical PCOS phenotypes (phenotype A (AOM, amenorrhea/oligomenorrhea + HA, hyperandrogenism + PCO, polycystic ovaries); Phenotype B: AOM + HA; Phenotype C: HA + PCO; and phenotype D: AOM + PCO, as defined by the Rotterdam criteria. Methods: This retrospective study included 227 women with one or more diagnoses of PCOS (ICD-9 256.4, ICD-10 E28.2) and 103 women without PCOS. All serum AMH levels were measured using Beckman Access-2 automated chemiluminescence assay and the age, BMI and AMH levels were analyzed using univariate analysis of covariance. Received operator curves were used to determine the AMH thresholds for predicting PCOS features and phenotypes. Results: Mean serum AMH levels were 9.96, 6.84, 6.43, 6.03, and 1.98 ng/ml in women with PCOS phenotype A, B, C, D, and control respectively. 101 (44.5%) patients were oligo/amenorrheic PCOS, 98 (43.2%) were hyperandrogenic PCOS, and 103 (45.4%) were PCO. Women with all three PCOS features had a significantly higher mean serum AMH compared to those with less of these features. The area under the curve (AUC) estimates of AMH showed high value ranging from 0.76 (95% CI, 0.71-0.81) in AOM group to 0.82 (95% CI, 0.79-0.88) in the PCO group. Conclusion: This study confirms the diagnostic opportunity of AMH test for discriminating between patients with PCOS phenotype and controls. High AMH accurately predicted PCOS in 92% (209 out of 227) patients diagnosed with PCOS. AMH value can predict PCOS in 78% women with oligo/amenorrheic PCOS, 77% with hyperandrogenic PCOS, and 79% with PCO. In keeping with the view that women with PCOS have a variety of phenotypic presentation that can be challenging to diagnose, using AMH test in combination with oligo/ amenorrhea or hyperandrogenism offers a non-invasive objective tool to screen patients with clinical features of PCOS.","PeriodicalId":147903,"journal":{"name":"Gynecology & Reproductive Health","volume":"12 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-10-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122220871","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Posterior Reversible Encephalopathy Syndrome in Pregnancy - Relevance in Diagnosis and Management","authors":"Rupalakshmi V, Meghana Mehendale, S. Bhandari, Ramesh Pundi, B. Rao","doi":"10.33425/2639-9342.1202","DOIUrl":"https://doi.org/10.33425/2639-9342.1202","url":null,"abstract":"Posterior reversible encephalopathy syndrome (PRES) is a cliniconeuroradiological syndrome, which may present with headache, encephalopathy, seizures, visual disturbances, and blindness. The lesions in PRES are due to vasogenic oedema in posterior cerebral hemispheres and can be reversible if managed accurately. MRI shows diffuse abnormal signal intensities involving deep white matter of occipital lobes. Reporting 4 cases of PRES diagnosed in our Lady Goschen Hospital, attached to KMC Mangalore in a duration of two years. In all four cases, PRES was suspected when patients presented with eclampsia persistent in spite of administration of Pritchard’s regimen. MRI confirmed diagnosis. Three of them recovered while one of the women succumbed due to status eclampticus, respiratory failure and shock. Clinical improvement with complete resolution of visual disturbances was observed with supportive treatment in the other 3 patients. In order to prevent irreversible brain damage, correct clinical suspicion and timely diagnosis with apt management is essential. If adequate blood pressure-titrated treatment is followed, there may be speedy recovery from eclampsia and hence improvement in maternal condition.","PeriodicalId":147903,"journal":{"name":"Gynecology & Reproductive Health","volume":"23 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-10-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127844155","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Profile of Antimicrobial Resistance and Sensitivity in Vulvar Abscesses in Women Attending a Tertiary Hospital","authors":"Mello Anelise Gomes de, Pereira Cintia Caus, Motta Fernanda Chagas Reuter, Souza Paloma Vieira de, Arrigoni Carolina Passos, C. Antônio","doi":"10.33425/2639-9342.1200","DOIUrl":"https://doi.org/10.33425/2639-9342.1200","url":null,"abstract":"Context: Vulvar abscess is a highly prevalent pathology in patients seeking emergency care; however, its epidemiology has yet to be fully clarified. Aims: This study aimed to determine possible risk factors, the most common microorganisms involved and the appropriate antibiotic therapy in cases of vulvar abscesses treated in a tertiary hospital. Settings and Design: This prospective study included 51 women who presented with a vulvar abscess and sought medical help at the hospital’s gynaecological emergency room over a 70-week period. Methods: Drainage of the abscess and microbiological analysis allowed the pathogen responsible for the lesion to be identified, as well as the profile of antimicrobial sensitivity and resistance to be determined. Statistical analysis: Frequencies and percentages, as well as means, medians and standard deviations, were calculated. Associations between the study variables were determined using the chi-square test or Fisher’s exact test. Results: Overall, 52.94% of the cultures were positive for methicillin-resistant Staphylococcus aureus (MRSA). There was no significant difference in age between the patients infected with MRSA and those infected with other agents (p>0.05). The MRSA isolates were sensitive to sulfamethoxazole + trimethoprim and to gentamicin, as were the great majority of the other pathogens. Shaving the vulvar region was the most important risk factor, being present in 74.5% of cases. Conclusion: MRSA is highly prevalent and a major cause of vulvar abscesses. Therefore, in these cases, an antibiotic therapy regimen with coverage for MRSA, such as sulfamethoxazole-trimethoprim, should be initiated as soon as possible.","PeriodicalId":147903,"journal":{"name":"Gynecology & Reproductive Health","volume":"226 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-10-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116850618","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Knowledge and Perception of Senior High School (SHS) Students about Emergency Contraceptive Use in the Garu and Tempane Districts","authors":"Christiana Asiedu, Ophelia Beyereh Dip, Rita Opoku-Danso","doi":"10.33425/2639-9342.1194","DOIUrl":"https://doi.org/10.33425/2639-9342.1194","url":null,"abstract":"The perception and knowledge people have about family planning health services are likely to affect the kinds of decisions they are likely to make about the service. The main purpose of the study was to assess the knowledge and perception of Senior High School students about emergency contraceptive use in the Garu and Tempane Districts. A descriptive (cross-sectional) survey design adopted. A questionnaire was administered to a sample of 248 students, who served as respondents. The sample was selected using the multistage sampling procedure. The data analyses were done using frequencies, percentages, mean and standard deviation and the independent sample t-test. The results showed that students had knowledge about emergency contraceptives. The results also, provided evidence that the students had negative perception about emergency contraceptive use. Furthermore, it was evident that male and female students had similar perception about emergency contraceptive use. It was recommended that the Ghana Health Service (GHS) should intensify their sex education as part of their health education programmes for students in the Senior High Schools.","PeriodicalId":147903,"journal":{"name":"Gynecology & Reproductive Health","volume":"32 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-08-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123870739","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Psychological and Social Effects of Infertility on Women: A Mixed Method Research","authors":"A. Olowokere, Jane O. Olowookere, A. Komolafe, O. Oyelade, A. Olajubu, Mercy K Aladegboye","doi":"10.33425/2639-9342.1193","DOIUrl":"https://doi.org/10.33425/2639-9342.1193","url":null,"abstract":"Background: Infertility is one of the most devastating experiences among infertile women in Nigeria. This is due to the socio-cultural significance attached to childbearing in Nigerian society. This study was conducted to assess and explore the psychological and social effects of infertility, identify the support system and coping strategies available to and utilized by infertile women selected from Gynecological Clinic of Owo Federal Medical Centre. Methods: The current research was a cross-sectional study and it used a convergent mixed method approach to collect data from September, 2017 to January, 2018. Structured questionnaire and in-depth interview guide were used to collect data from 152 and 10 infertile women who were selected by purposive sampling. Quantitative data were analyzed using descriptive statistics and multinomial logistics regression in SPSS20 at 0.05 level of significance. The interviews were analyzed via content analysis. Results: The most prevalent psychological and social effects of infertility experienced by the women were frustration with the different treatment procedures (79.6%) and having sex for purpose of procreation only (78.9%). Higher age (OR = 2.95, CI = 1.68 - 5.29, P=0.01), monogamous family (OR = 6.70, CI = 1.68 - 26.74, P = 0.01) and parity (OR = 4.21, CI = 0.42 - 41.76, P=0.03) significantly influenced psychological effects of infertility while zero parity (OR =1.34, CI = 0.89 - 4.56, P = 0.01) was the only factor that significantly determine the social effects of infertility. The qualitative results show that the women experienced a range of psychological and social issues ranging from grief to negative self-concept, inordinate desire for sexual intercourse, societal stigma, social withdrawal and isolation. Conclusion: The study concluded that infertile women experience a range of psychological and social issues. The findings from both the quantitative and qualitative assessment indicated the need to provide more psychosocial support for women with infertility.","PeriodicalId":147903,"journal":{"name":"Gynecology & Reproductive Health","volume":"12 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-08-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116419769","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}