Gynecology & Reproductive Health最新文献

{"title":"A Review of Artificial Oocyte Activation with Calcium Ionophore for Fertilization Failure and a Case Report of a Successful Twin Pregnancy","authors":"Jerome H. Check, D. Summers, D. Horwath, Michael Sobel, Brooke Neumann","doi":"10.33425/2639-9342.1232","DOIUrl":"https://doi.org/10.33425/2639-9342.1232","url":null,"abstract":"A","PeriodicalId":147903,"journal":{"name":"Gynecology & Reproductive Health","volume":"29 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-10-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139307034","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Gestational Trophoblastic Disease: A Case of Hydatidiform Mole Concurrent with Twin Pregnancy","authors":"Ribeiro João, Aguiar Adriana, Botelho Lara, Faria Catarina, Mussielo Rubens, Ferreira Rodrigo, Filho Antônio","doi":"10.33425/2639-9342.1235","DOIUrl":"https://doi.org/10.33425/2639-9342.1235","url":null,"abstract":"Gestational Trophoblastic Disease (GTD) is a clinical entity characterized by abnormal cell proliferation affecting cells of trophoblastic tissue. Within the spectrum of the disease, Complete Hydatidiform Mole and Partial Hydatidiform Mole are the most common entities. However, cases of Hydatidiform Mole concurrent with twin pregnancy are rare. The present report aims to describe a case of twin pregnancy in an 18-year-old patient, consisting of a normal fetus and placenta associated with a Partial Hydatidiform Mole, which progressed to miscarriage around the 17th week of gestation, covering from the moment of presentation at the Emergency Room to outpatient follow-up post-hospital discharge.","PeriodicalId":147903,"journal":{"name":"Gynecology & Reproductive Health","volume":"16 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-10-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139308062","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Enabling the ‘Breastfeeding-Work Dyad’ and Understanding the Contextual Pentad of Productive Work, Reproductive Work, Reproductive Health, Reproductive Rights and Reproductive Politics: The Tantalizing Microcosmic Perspectives Encapsulated with Some Imaginatively Innovative Interventions","authors":"Charles Osayande Eregie","doi":"10.33425/2639-9342.1234","DOIUrl":"https://doi.org/10.33425/2639-9342.1234","url":null,"abstract":"This ‘Invited Narrative Review’ seeks to explore how best to ‘Enable Breastfeeding-Work Dyad’ extrapolated from conceptualizing the ‘Contextual Pentad Components’ which have been disposed to reflect ‘Optimality begetting Optimality’ and situate with ‘Logical Sequential Flow’ re: ‘Optimal Productive Work’ flows from ‘Optimal Reproductive Work’ which itself flows from ‘Optimal Reproductive Health’ ultimately flowing from ‘Optimal Reproductive Rights’ also flowing from, and encapsulated and facilitated by, ‘Optimal Reproductive Politics’. ‘Optimal Infant and Young Child Feeding’ is reportedly a ‘Programmatic Fulcrum’ of ‘Optimal Reproductive Work’. The Treatise is replete with ‘Tantalizing Teasers’ to stimulate and invite further ‘Contextual Conversational Surfing’. The ‘Thrust’ of the Narrative Review: ‘Enabling the Breastfeeding-Work Dyad’ mirrors the ‘2023 World Breastfeeding Week Theme’ which is ‘Enabling Breastfeeding: Making a Difference for Working Parents’. Some ‘Imaginatively Innovative Initiatives/ Interventions’ are ventilated to whet the appetite. ‘Breastfeeding’ is a ‘Low-cost High-impact Strategy’ to achieve ‘Optimal Reproductive Work’ for engendering ‘Optimal Productive Work’.","PeriodicalId":147903,"journal":{"name":"Gynecology & Reproductive Health","volume":"334 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-10-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139309277","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Differential Protein Expression of mild to severe forms of Endometriosis in South Indian Ethnic patients","authors":"R. Rozati, Naila Mohiuddin, V. A. Ayapati, Wajeeda Tabasum, Gautam Mehdi Ayapati, Taalia Nazeer Ahmed, Sumaiya Nayela, Aleem Ahmed Khan, Afraa Mohammad, Abid Ali","doi":"10.33425/2639-9342.1236","DOIUrl":"https://doi.org/10.33425/2639-9342.1236","url":null,"abstract":"Introduction: Endometriosis is a prevalent, benign, estrogen-dependent, chronic gynecological disorder associated with pelvic pain and infertility. Despite its prevalence and impact on reproductive health, the underlying molecular mechanisms and differential protein expression patterns associated with different disease severity levels remain poorly understood. Key components such as extracellular matrix (ECM) components (laminins, fibronectins), adhesion molecules, cytokines, and growth factors have been shown to contribute to the pathogenesis of Endometriosis. However, the precise nature of these molecular networks and Signalling pathways remain incompletely understood, necessitating further investigation. In our study, we employed proteome profiling techniques to analyze endometrial tissue samples from women with severe forms of endometriosis, comparing them with samples from normal controls. Objective: It is to identify alterations and dysregulations in specific proteins and pathways associated with endometriosis. We utilized high-resolution two-dimensional gel electrophoresis (2-DE) and matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS) for protein expression analysis and identification during the mid-secretory phase. Findings: We identified thirty differentially expressed proteins, including ZC3H13, Tax1bp1, ANKRD36, ZNF658B, MALRD1, and PRRC2A. Notably, a strong association was observed among genes encoding three metabolic enzymes. Enrichment analysis revealed numerous pathways related to endometriosis-related morbidity in KEGG, WiKi, and Reactome databases, underscoring the significant role of these proteins. Conclusion: This study employed proteome profiling techniques to analyze endometrial tissue samples from women with severe forms of endometriosis, comparing them with samples from normal controls. The research identified thirty differentially expressed proteins, including ZC3H13, Tax1bp1, ANKRD36, ZNF658B, MALRD1, and PRRC2A. Notably, a strong association was observed among genes encoding three metabolic enzymes. Enrichment analysis revealed numerous pathways related to endometriosis-related morbidity, emphasizing the significant role of these proteins. This research enables the development of accurate diagnostic tools and personalized treatments by identifying specific proteins and pathways associated with endometriosis. The identified proteins also have the potential to serve as biomarkers for disease progression, aiding in monitoring and assessing treatment efficacy.","PeriodicalId":147903,"journal":{"name":"Gynecology & Reproductive Health","volume":"57 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-10-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139306328","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Insight, Knowledge and Vaccination Against COVID-19 Among Pregnant Women in Two Tertiary Hospitals Southeast Nigeria, Four Years After Onset of the Pandemic","authors":"M. Nwali, Nwali Nneka Immaculata","doi":"10.33425/2639-9342.1233","DOIUrl":"https://doi.org/10.33425/2639-9342.1233","url":null,"abstract":"Background: The study was conducted in two tertiary hospitals located in ababkaliki the capital city of Ebonyi State. These are referral centers that served the state and the neighboring states. Methods: This was a prospective study in which pregnant women accessing antenatal care in the centers were consecutively recruited till the sample size was obtained. Information on sociodemographic characteristics like age, gravidity, occupation, Religion and educational level were obtained. Insight, awareness and vaccination of COVID-19 Disease also obtained were obtained. The aim of the study was clearly explained to the women and informed consent was signed prior to recruitment into the study. The exclusion criterion was those who did not sign consent. Results: A total of 250 pregnant women who consented were recruited into the study. The mean age was 30.2 (SD 5.3) and ranged between 18yers to 44 years. The highest age group was 30 to 39years (55.2%) followed by those aged between 20 to 29 years (40%). The median gravidity of the respondents was 2.6 (SD 2.0) and ranged between 1 to 7. Majority were traders (34.4%) followed by civil servants (19.2%), thirdly students (16.0) and self-employed (13.2%). Most of them (98.3%) were Christians while 96.4% had tertiary education (62.8%). The awareness of COVID-19 was high but very poor knowledge of spread 18.8% and preventive measures 20.8%. Vaccine uptake was low 21.2% with major reason being fear of side effect (22.4) though 36% gave no reason while some believed vaccine is a scam. Conclusion: There was high insight of COVID-19 disease among these pregnant women but very poor knowledge of its mode of spread and preventive measures as well as very low uptake of anti-COVID-19 vaccines 4 years on from the onset of the pandemic.","PeriodicalId":147903,"journal":{"name":"Gynecology & Reproductive Health","volume":"24 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-10-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139309108","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Nurses’ Knowledge, Attitudes, and Practices regarding perinatal bereavement care in Malaysia: A Cross-sectional Study","authors":"Kiu Ling Ting, A. Ahmad, A. Kunjukunju, Puziah Yusof","doi":"10.33425/2639-9342.1231","DOIUrl":"https://doi.org/10.33425/2639-9342.1231","url":null,"abstract":"Background: Perinatal bereavement occurs when a parent experiences the loss of a baby during pregnancy or shortly after birth. Coping with this loss can be incredibly challenging and emotionally taxing for the parents involved. They often have complex and intense emotional and psychosocial needs to navigate during this difficult time. Objective: This study aimed to investigate nurses’ knowledge, attitudes, and practices regarding perinatal bereavement care (PBC) and its correlation with their selected sociodemographic factors. Methods: In 2021, a cross-sectional descriptive study was conducted utilising a structured questionnaire for data collection. A total of 182 nurses were sampled conveniently, comprising 45 registered nurses, 124 registered midwives, and 13 community nurses. The data was subjected to descriptive statistical analysis using IBM SPSS Version 28.0. Results: The finding shows that 67% had a poor understanding of perinatal bereavement. However, the majority (85.2%) had positive attitudes towards providing care for those affected by perinatal bereavement, and 58.8% displayed favourable care behaviour. The results also indicated that nurses who had experience working with grieving parents had a higher level of knowledge regarding perinatal bereavement care (p<0.005). Additionally, the study found that nurses who had been working in the field for longer had more positive attitudes toward bereavement care (p<0.05). Furthermore, the practices of perinatal bereavement care were found to be related to work designation and qualifications (p<0.05). Conclusion: It is recommended that perinatal bereavement care education be included in undergraduate healthcare education, postgraduate education, and Continuing Professional Education (CPE) workshops. Evidence-based policies and protocols on perinatal bereavement care are also recommended to support parents and family members during their experience of bereavement.","PeriodicalId":147903,"journal":{"name":"Gynecology &amp; Reproductive Health","volume":"5 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-08-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139347459","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Knowledge of Zygote Cryopreservation among Female Lecturers in Universities in Enugu State, Nigeria","authors":"Iheanacho Il, Nweze So, Ugwuegede Cm, Ani Nr, Ezenwaeze Mn, Nnabueze Uc","doi":"10.33425/2639-9342.1229","DOIUrl":"https://doi.org/10.33425/2639-9342.1229","url":null,"abstract":"One of the viral indices of stable family life and living in most societies is the capacity to procreate hence the need for examination of knowledge of female lecturers on possible ways to actualize it. The study investigated knowledge of oocyte cryopreservation among female lecturers in universities in Enugu State in a cross-sectional descriptive survey involving 171 female lecturers from six out of seven universities in Enugu State. Purposive and proportionate sampling procedures were used in selecting the six Universities and 171 female lecturers used for the study respectively. Self-administered questionnaire was used as instrument for data collection while data analysis was carried out with frequency counts and percentages. The results showed that female lecturers in universities in Enugu State had low level of knowledge on oocyte cryopreservation, reasons for oocyte cryopreservation and procedure involved in oocyte cryopreservation (36.49%;38.36%;30.29%). Furthermore, majority of the respondents were not knowledgeable enough in most of the medical health challenges that could necessitate oocyte cryopreservation. It was concluded that there is low level of knowledge on oocyte cryopreservation, reasons for oocyte cryopreservation as well as the procedures involved in oocyte cryopreservation among female lecturers in universities in Enugu State. The recommendation among others is that Clinicians should endeavor to discuss the possibility of oocyte cryopreservation for medical and elective purposes during clinical meetings especially for single women of child bearing age who may wish to delaying procreation. Consequently, there is the need to set up counseling centres in major cities and towns in Enugu State in order to allay women ‘s fears about possible unfavourable outcomes of the procedures.","PeriodicalId":147903,"journal":{"name":"Gynecology &amp; Reproductive Health","volume":"29 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-08-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139347275","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Traditional Birth Attendant in the Maternal and Child Health Space in Nigeria: Ancient Practices and Modern Recommendations","authors":"Ibama As, Unamba Bc, Jaja E, Ogbonna C, Onawola Rm, Ugwuoke A, Ibulubo Ri, Ibulubo Tg","doi":"10.33425/2639-9342.1230","DOIUrl":"https://doi.org/10.33425/2639-9342.1230","url":null,"abstract":"Background: Arguments on the usefulness of Traditional Birth Attendants (TBAs) in maternal and child health care and the reduction of maternal and child morbidity and mortality indices or not, persist. This paper sought to explore the ancient practices of TBAs and to strike a balance to portray modern recommendations that would contribute to improved maternal and child health status. Methods: The method used was review of relevant literatures from open-access journals and google scholar data base, as well as research reports on variables of the subject in developing countries. Results: Findings revealed that the overlapping root of TBAs’ practice burden include poor social amenities, inadequate health facilities and services in rural areas where over 70% of the population reside. While evidencebased report showed that even when 93% of rural women registered for Ante-Natal Care, 49% were delivered at home by TBAs and 73% has sought help from them for retained placenta with bleeding. Also, 41% of women of child bearing age indicated that maternal and child infection is a risk associated with the patronage of TBAs, whereas 32.8% indicated that bleeding during and after delivery were equally risks associated with TBA-provided maternal health services. Such circumstances of service were associated with harmful practices with attendant health and medical complications to recipient mother and child. However, helpful ancient practices of TBAs include; home visiting to promote well-being of mother and child (9.84%), sitz bath (17.20%), encouraging breastfeeding up to 2years (18.90%) etc. The modern recommendations, x-rayed the remedial actions on the harmful practices and associated negative consequences to improving maternal and child health indices in Nigeria. Conclusion: For reasonable and sustainable reduction in the burden associated with the practices of TBAs in maternal and child health care in Nigeria, contextual focused training and continuous mentoring is a necessity.","PeriodicalId":147903,"journal":{"name":"Gynecology &amp; Reproductive Health","volume":"32 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-08-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139347224","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Relationship between Preterm Premature Rupture of Membranes and Colonization of GBS - A Review","authors":"Gali Levy, O. Gutzeit, Saar Aharoni, Dana Vitner","doi":"10.33425/2639-9342.1228","DOIUrl":"https://doi.org/10.33425/2639-9342.1228","url":null,"abstract":"Purpose: Group B streptococcus (GBS) is the leading cause of newborn infection. The most important risk factor for this debilitating infection in newborns is maternal colonization of the genitourinary and gastrointestinal tracts. This review investigates three main questions and what answers exist in the current literature. The first question seeks to investigate whether there is a causal relationship between GBS infection and Preterm Premature Rupture of Membranes (PPROM). The remaining questions in this review investigate the management of PPROM pertaining to the optimal time of delivery and the antibiotic treatment best suited for GBS colonized women. Methods: A Pubmed www.pubmed.orgsearch was performed (1996-2020), using preterm rupture of membranes and GBS as the primary medical subject heading, reporting randomized clinical trials, quasi-experimental trials, and analytic studies) including retrospective and prospective cohort studies). We also searched Google for preterm rupture of membrane intervention programs and prenatal care clinics published online. Results: We found 39 studies in our search that investigated the relationship between GBS colonization and PPROM. Of these studies, 5 were randomized control trials (RCT), 8 were retrospective, and 4 were systematic reviews. Most of the studies did not show an association between GBS and PPROM. All the studies showed a benefit in antibiotic treatment however none considered specific treatment in the setting of GBS and PPROM. As for management, most of the studies did not show a benefit of expectant management or immediate delivery for these women. Conclusion: There is no clear-cut association between PPROM and GBS. Many studies have sought out to find a significant association, but the more studies exist, the more answers exist to the question being investigated. Practices involving prophylactic antibiotic treatment at the time of PPROM and again at the time of delivery is the most beneficial management which decreases intraamniotic infection, vertical transmission, and risks of neonatal sepsis after birth. Expectant management of delivery was not found to be more effective than active management in women with PPROM and GBS colonization.","PeriodicalId":147903,"journal":{"name":"Gynecology &amp; Reproductive Health","volume":"13 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-08-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139347357","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Ovarian Cystadenofibroma: Case Report","authors":"İ. K, Wajih O, Berrehili H, Tossi S, Boufettal H, Mahdaoui S, Samouh N","doi":"10.33425/2639-9342.1227","DOIUrl":"https://doi.org/10.33425/2639-9342.1227","url":null,"abstract":"Ovarian cystadenofibromas are rare ovarian tumors. The clinical presentation is non-specific. The diagnosis can be made on imaging or anatomopathology. The appearance may be in favor of a malignant tumor. However, the surgeon must remain vigilant to avoid radical surgery in the face of this benign tumor.","PeriodicalId":147903,"journal":{"name":"Gynecology &amp; Reproductive Health","volume":"2 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-08-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139347857","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}