Gynecology & Reproductive Health最新文献

{"title":"Triple Negative Breast Cancer In Young Pregnant Women – Trhee Proposed Cases","authors":"Botelho Lara, DE Carvalho Marina, Chambô Danielle, Filho Antônio, Pereira Cecília, Muniz Izabela, Lopes Marcela","doi":"10.33425/2639-9342.1225","DOIUrl":"https://doi.org/10.33425/2639-9342.1225","url":null,"abstract":"Pregnancy-associated breast cancer (PABC) is malignant neoplasm of the breast diagnosed during pregnancy or up to one year after delivery. Triple negative breast cancer (TNBC) is more common in patients younger than 50 years and has a more aggressive character. The treatment of PABC should consider the type of tumor, the stage of the disease, the gestational age at the time of diagnosis and the wishes of the patient and family members. The firstline treatment, due to the contraindication to radiotherapy during pregnancy, is radical mastectomy. Chemotherapy drugs are contraindicated in the first trimester and outside this period, their use must be carefully and discussed. Breast tumors found in pregnant women, in addition to being diagnosed in more advanced stages, are often more aggressive, of the triple negative type, demonstrating the relevance of the association of both for discussion. For this reason, the present study aims to report 3 cases of young patients diagnosed with breast cancer associated with triple negative pregnancy.","PeriodicalId":147903,"journal":{"name":"Gynecology & Reproductive Health","volume":"94 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139367706","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Giant Chorioangioma with Oligohydramnion: A Case Report","authors":"Muhidin Abdo, Lukman Yusuf","doi":"10.33425/2639-9342.1222","DOIUrl":"https://doi.org/10.33425/2639-9342.1222","url":null,"abstract":"Chorioangioma or chorangioma is the most common non-trophoblastic benign and angiomatous vascular tumor of the placenta with a prevalence rate of 0.6-1%. It was first described by Clark in 1798. The smaller types of less than 4-5cm occurring in less than 1:10,000 pregnancies tend to be asymptomatic and clinically not significant while larger chorioangiomas found in over 1:16,000 births could manifest with adverse maternal, fetal and neonatal outcomes. The tumor related manifestations in this case report encompass a multitude of features that displayed a placental mass of 8.5 x 8.6cm, oligohydramnion, intrauterine growth restriction, poor biophysical profile and a preterm breech that culminated in an emergency cesarean delivery. The intent of the article is to create awareness of the possible pathology among practitioners, raise a high index of vigilance and establish early diagnosis, prognosticate and enhance the concept of birth preparedness and complication readiness.","PeriodicalId":147903,"journal":{"name":"Gynecology & Reproductive Health","volume":"29 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139367619","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Demons Meigs Syndrome: About Two Cases.","authors":"I. K, W. O, T. S., Gourja Y, B. H, M. S, S. N","doi":"10.33425/2639-9342.1226","DOIUrl":"https://doi.org/10.33425/2639-9342.1226","url":null,"abstract":"Demons Meigs syndrome is the association of a benign ovarian tumor, a peritoneal and pleural effusion. Its physiopathology is still obscure till today. Through a rare case, and a review of the literature, we will discuss the diagnostic, etio-pathogenic, therapeutic, and evolutionary criteria of this syndrome.","PeriodicalId":147903,"journal":{"name":"Gynecology & Reproductive Health","volume":"45 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139366489","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Benign Squamous Papilloma of the Vulva","authors":"Sowjanya Kurakula, V. Muralidharan, Shravani Rama, Abhijna Rao Kompella, N. N","doi":"10.33425/2639-9342.1224","DOIUrl":"https://doi.org/10.33425/2639-9342.1224","url":null,"abstract":"","PeriodicalId":147903,"journal":{"name":"Gynecology & Reproductive Health","volume":"45 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139366623","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Adenomyosis: Current knowledge, Recent Advances and Future Perspective","authors":"Kunal Rathod, Michael Magro, Sarah Shehzad, Yatin Thakur, Sherif Daoud","doi":"10.33425/2639-9342.1223","DOIUrl":"https://doi.org/10.33425/2639-9342.1223","url":null,"abstract":"Aim: Adenomyosis is an abnormal overgrowth of the endometrial tissues within the myometrium causing enlargement of the uterus. This present review will focus on clinical symptoms, diagnostic approach, image findings, complications, and management of Adenomyosis. The goal is also to highlight the recent advances in the topic. Methodology: A total of 15 articles published in various journals have been included to write the current review. PubMed, Research Gate, Scopus, Springer are some of the databases used for the literature search. Results: After reviewing the literature Adenomyosis has been discussed under the following topics 1) epidemiology (known and emerging risk factors) 2) Pathogenetic Theories (recent advances such as sequencing analysis of epithelial cells in Adenomyosis) 3) Clinical Manifestations and impact on women's fertility and pregnancy outcome 4)Diagnostic Approach, Current imaging techniques and classifications 5) Medical Management 6) Surgical Interventions (with recent advances such as UAE) 7) Future Perspective. Conclusion: The prevalence of Adenomyosis is still unknown owing to the lack of a validated standard diagnostic approach. Historically, the standard treatment of adenomyosis has been hysterectomy, but this is not always the best option, especially for women who want to preserve their fertility or for those who are poor surgical candidates.","PeriodicalId":147903,"journal":{"name":"Gynecology & Reproductive Health","volume":"327 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139366851","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"First Trimester Bleeding in Pregnancy within the Gynecology and Obstetrics Department of Sourô Sanou Teaching Hospital in BoboDioulasso: 422 Cases Studied and Literature Review","authors":"Bambara Moussa, O. Issa, K. Evélyne, N. Francis","doi":"10.33425/2639-9342.1206","DOIUrl":"https://doi.org/10.33425/2639-9342.1206","url":null,"abstract":"Objectives: Study the epidemiological, clinical, therapeutic and prognostic aspects of the first trimester bleeding of pregnancy. Methodology: This was a descriptive cross-sectional study conducted within the Gynecology and Obstetrics Department of Sourô Sanou Teaching Hospital from January 1st to December 31st, 2019. The study included any patients admitted and treated for endo uterine bleeding in pregnancy with a term inferior or equal to 15 weeks of amenorrhea. The parameters studied were the following: sociodemographic characteristics (age, parity, level of education, occupation, marital status, origin), clinical and paraclinical aspects, diagnosis retained, treatment, and maternal prognosis. Information was collected from a survey form, from clinical records, operating protocols and anatomopathological reports. Data entry and analysis was made through Word and Epi-info 7.2.3 software. Results: During the period of study, 422 cases of first trimester bleeding were reported, corresponding to a frequency of 10.33%. The average age was 29 ± 6.4 years [15-49 years] and the average parity was 1.95 ± 1.7 [0-11]. Married women accounted for 75% of the population. The average gestational age was 9.14 weeks of amenorrhea [5-14 weeks of amenorrhea]. Clinical signs were dominated by vulvar bleeding in 100% of cases and pelvic pains in 86% of cases. All our patients had gone through pelvic ultrasound. As for the diagnoses retained, these included: a threatened abortion in 11.84% of cases, an incomplete abortion (46.77% of cases), an ectopic pregnancy (EP) (26.8% of cases), a terminated pregnancy (17.9% the cases) and a molar pregnancy (8.3% of cases).Abortions were managed through MVA (68.27%) and medical abortion (4.8%). All the cases of EP were treated surgically and no maternal deaths were recorded in our study. Conclusion: First trimester bleeding in pregnancy is common within the department. The main etiologies are threatened abortion, incomplete abortion, molar pregnancy and ectopic pregnancy.","PeriodicalId":147903,"journal":{"name":"Gynecology & Reproductive Health","volume":"615 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123076446","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Intravesical Stone Following IUD Trans Utero-Vesical","authors":"S. Traore, Ousmane Dembélé, S. Traoré, S. F, Sebou Koné, Soya Toure, Laya Niangaly, Kateneme S Ouattara, O. Berthe, S. Coulibaly, Aly Bd, Ternan T, Abdoulaye S, A. D., D. M., D. Am, B. Traoré, M. Kante, M. D., Dade Bh, Madou T","doi":"10.33425/2639-9342.1209","DOIUrl":"https://doi.org/10.33425/2639-9342.1209","url":null,"abstract":"Background: Intravesical lithogenesis following IUD intrauterine device migration is a serious complication which has been rarely reported. Case Report: Here in, we report the case of 46 aged woman, 7th gestation and 7th parity, who started with periodic complains of pollakiuria, burning and urgenturia 6 months after IUD insertion. Ultrasonography and Plain abdominal X ray evoked an intra bladder T device witch branch was enclosed by lithiasis. Referred to the hospital for proper management, the diagnostic confirmation has been done by uretrocystoscopy. A cystolithotomy was performed and post operatory follow up has been uneventful. Rapid specialized management is advisable face to IUD cord missing, especially when this is associated to LUTS (low urinary tract syndrome).","PeriodicalId":147903,"journal":{"name":"Gynecology & Reproductive Health","volume":"256 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122707841","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Comparison of Visual Findings at Hysteroscopy with Endometrial Biopsy Histology among Women Being Investigated for Postmenopausal Bleeding","authors":"J. Mamah, A. Onyebuchi, Zubaida Abubakar-Aliyu, Nnaemeka Egbuonu, Obinna Oraekwe","doi":"10.33425/2639-9342.1205","DOIUrl":"https://doi.org/10.33425/2639-9342.1205","url":null,"abstract":"Between 90-95% of patients diagnosed with endometrial cancer present with postmenopausal bleeding. Hysteroscopy and endometrial biopsy are vital tools in the investigation of women with postmenopausal bleeding. Accurate interpretation of visual findings during hysteroscopy is an important requirement in the diagnosis and management of PMB. We undertook an audit of findings of hysteroscopies performed on women with postmenopausal bleeding and compared with histology report of endometrial biopsy taken during the hysteroscopy. Findings will be used to improve service delivery. A retrospective review was conducted between July 2019 to December 2019. Structured proforma was used for anonymised data collection and entered into an excel spreadsheet of the 2018 version. Descriptive statistical analysis was followed to determine frequencies and percentages. Accuracy of hysteroscopic findings was measured against endometrial biopsy histology report. A total of 133 patients referred for postmenopausal bleeding met the criteria for hysteroscopy and endometrial biopsy. The mean age of the participants was 60 years. The overall accuracy of hysteroscopic visual diagnosis of endometrial pathology was 75.0%. The sensitivity and specificity were 80.0% and 88.0%, while the positive predictive value (PPV) and negative predictive value (NPV) were 66.7%, and 93.8% respectively. Specificity and NPV were 100% and 93.8% for endometrial cancer, which was diagnosed in 7.5% of the patients. In conclusion, we found that compared with histologic diagnosis, three quarter of the women with histology confirmed endometrial pathology were correctly identified during hysteroscopy. Hysteroscopy had a high specificity and negative predictive value in excluding endometrial cancer. There is room for more training and skills enhancement.","PeriodicalId":147903,"journal":{"name":"Gynecology & Reproductive Health","volume":"54 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125050915","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparison of Adjunctive Use of G-CSF Vs Autologous PRP in IVF Patients with a Refractory Thin Endometrium: A Retrospective Record Review","authors":"Mohamed Iqbal Cassim, T. Mohamed, Y. Dasoo, J. Carlse, Simoné Budler, Erwin Rathipal, M. Ayob, Jeanne Saron Nissieh Sokoni, Suhail Dudhia, Mohamed Fayaaz Cassim","doi":"10.33425/2639-9342.1210","DOIUrl":"https://doi.org/10.33425/2639-9342.1210","url":null,"abstract":"Background: In Vitro Fertilization (IVF) is an important treatment option in the management of couples with infertility. Sadly, however, failure to achieve a pregnancy through IVF is not uncommon. Amongst the many causes of IVF failure, implantation failure has emerged as one of the more common and important factors. The refractory thin endometrium as a cause of recurrent IVF failure has been well documented. The use of either Granulocyte Colony Stimulating Factor (G-CSF) or autologous Platelet Rich Plasma (PRP) has emerged as potential adjunctive treatments that may mitigate the rate of implantation failure; however, no conclusive evidence exists to favour the use of one over the other. Objective: To compare the measured change in endometrial thickness and pregnancy rates in patients with Recurrent implantation Failure (RIF) and/or thin endometrium following the intrauterine administration of either G-CSF or autologous PRP. In addition, to compare the pregnancy rates in patients with fluid in the endometrial cavity who underwent either therapy. Design: A retrospective analysis was conducted on patients who underwent endometrial therapy (either G-CSF or PRP) between January and June 2020. The measured change in endometrial thickness and the clinical pregnancy outcome of the two groups were compared. Subjects: 36 patients with a mean age of 40.36 years met the inclusion criteria of the study. 20 received autologous intrauterine PRP treatment and 16 received intrauterine G-CSF treatment. Both groups were well matched for age, pre-intervention endometrial thickness and embryo quality. Intervention: Administration of G-CSF (One ampoule Neupogen® (filgrastim)) or PRP (1ml) into the uterine cavity transcervical 48 hours prior to embryo transfer. Main Outcome Measures: The change in endometrial thickness measured 48 hours prior to embryo transfer and at the time of embryo transfer (ET) was compared. Positive clinical pregnancy outcome was determined by a positive serum B-HCG test 10 days post insertion. A statistically significant difference was set at p=0.05. Results: There was a statistically significant difference in endometrial expansion post intervention in both the G-CSF and PRP groups. However, the difference between the two groups did not reach statistical significance (p=0.077). Additionally, the collective pregnancy rate of the total study population was 44.4% (16 of 36), a significant increase over the expected pregnancy rate in the published literature [1,2]. Of the positive pregnancies, 9 (56.25%) were in the autologous PRP group and 7 (43.75%) in the G-CSF group. This difference was, however, determined not to be statistically significant (p=0.603). Conclusion: Both G-CSF and PRP are effective interventions in the management of the thin refractory endometrium. Both result in significant endometrial expansion and increased pregnancy rates. Despite a marginally higher endometrial response and pregnancy rate in the PRP group, the differences ","PeriodicalId":147903,"journal":{"name":"Gynecology & Reproductive Health","volume":"29 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131733975","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prevalence and Barriers to Contraceptive Uptake among Reproductive Age Women in Achi, Enugu State, Southeast, Nigeria","authors":"Onyekpa Ifeanyi J, Odugu Boniface U, Nevo Calistus O","doi":"10.33425/2639-9342.1208","DOIUrl":"https://doi.org/10.33425/2639-9342.1208","url":null,"abstract":"Background: Contraceptives are methods used to prevent pregnancies because of coitus. It is a major determinant of pregnancy and birth rates worldwide. Nigeria, like many other developing countries has a low prevalence rate of contraception, hence, the need to improve awareness and availability of modern contraceptives to reduce the unmet need and avail our women the opportunity to enjoy the numerous benefits derivable from it. Aim: To determine the prevalence, awareness and barriers to contraceptive uptake among the rural women. Materials & Method: It was a cross-sectional study of women of reproductive age in Achi. A multi-stage sampling technique was used to recruit respondents from the communities in the town. A questionnaire administered by the interviewer was used to collect relevant data, which was subsequently analyzed using SPSS version 20.0 computer software for Windows. The result was presented using tables, means and percentages. Result: Four hundred and twenty two (422) women were recruited into the study. Majority of them were 25-29 years (34.6%) whereas the least were 15-19 years (4.33%) of this number, 68.2% had secondary education and majority of them farmers (27.5%). About 40% were orthodox Christians and the rest Catholics and Pentecostals. Also, 316 (74.9%) of the women did not use any contraceptive method giving us a contraceptive prevalence of 25.1%. Two hundred and eight (49.3%) had 3 to 4 surviving children while only 43 (0.2%) had no child. Most the women on contraceptives used injectables,(11.1%), 4.7% used implants and only 0.2% used oral pills. Of the possible reasons for non-acceptance considered majority had fear of carcinogenesis 133(31.5%), followed by husbands’ opposition 110(26.1%) while 19(4.5%) considered contraceptives unhealthy. Conclusion: There is still a low prevalence of contraception in Achi suggesting a high burden of unmet contraceptive needs. Efforts should be channelled towards unravelling the remote and immediate causes of the low prevalence so as to proffer a lasting solution to the problem.","PeriodicalId":147903,"journal":{"name":"Gynecology & Reproductive Health","volume":"5 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121820862","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}