Santos Alexandre Bobbio dos, Pancieri Barbara Gobetti, Rios Camila Correia, B. E. S. Leticia Lanna de, Musiello Rubens Bermudes, C. Antônio
{"title":"The Rare Association of Ectopic Pregnancy and Hydatidiform Mole: A Case Report","authors":"Santos Alexandre Bobbio dos, Pancieri Barbara Gobetti, Rios Camila Correia, B. E. S. Leticia Lanna de, Musiello Rubens Bermudes, C. Antônio","doi":"10.33425/2639-9342.1195","DOIUrl":"https://doi.org/10.33425/2639-9342.1195","url":null,"abstract":"An ectopic molar pregnancy is a rare event, occurring in 1 in every 20,000–100,000 pregnancies. The condition may present as a complete or partial molar pregnancy and the ectopic site can vary as in a non-molar ectopic pregnancy. When a molar pregnancy presents as a tubal ectopic pregnancy, the risks related to both conditions, including tubal rupture and progress to malignancy, are compounded. The definitive diagnosis is normally reached by histopathology of the surgical specimen, since imaging tests are usually unable to differentiate between a molar and a non-molar ectopic pregnancy. While the specific histological findings may confirm the diagnosis of hydatidiform mole, immunohistochemistry is essential to differentiate between a complete and a partial molar pregnancy. Although in the majority of cases surgical resection is considered the definitive treatment, it is estimated that 20% of patients with a molar pregnancy may develop gestational trophoblastic neoplasia, hence requiring a risk-specific follow-up. This report describes a case of a tubal molar pregnancy and includes a review of clinical, diagnostic and therapeutic aspects, as well as a discussion on the particularities of this rare association.","PeriodicalId":147903,"journal":{"name":"Gynecology & Reproductive Health","volume":"58 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-08-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126683290","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Maximizing Correction of Infertility with Moderate to Marked Diminished Egg Reserve in Natural Cycles by Up-Regulating Follicle Stimulating Hormone Receptors","authors":"J. Check, J. Choe","doi":"10.33425/2639-9342.1197","DOIUrl":"https://doi.org/10.33425/2639-9342.1197","url":null,"abstract":"Many infertility specialists advise women with diminished oocyte reserve (DOR) that their remaining oocytes probably are of poor quality similar to women of advanced reproductive age. There have been studies, especially employing in vitro fertilization-embryo transfer (IVF-ET), showing very poor live delivered pregnancy rates despite the transfer of morphologically normal embryos in women even with mild DOR. However, other data suggests that the low pregnancy rates are related to the use of high dosages of follicle stimulating hormone (FSH) drugs which down-regulate some key FSH dependent enzymes, cytokines, or proteins required for proper embryo implantation. Some studies have shown that techniques that favor FSH receptor up-regulation, rather than down-regulation, can provide the chance of live delivery 80% as well in women ≤ 35 with DOR, 70% for women 36-39, and 50% for women 40-42. Though some infertility specialists will encourage women whose only infertility issue is DOR, who reject the initial suggestion to consider donor oocytes, to proceed immediately with IVF-ET to maximize success, pregnancies are quite possible with natural conception. Thus, it seems imprudent to make couples undergo the financial burden of IVF-ET in the absence of a significant tubal or male factor problem. Not only have live deliveries occurred in women with DOR, using the principle described to achieve a mature dominant follicle followed by proper luteal phase support, with serum FSH levels over 100 mIU/mL, but also serum Anti-Mullerian Hormone (AMH) levels that were undetectable. This even applies to women in overt menopause where FSH up-regulation was achieved by negative feedback to the pituitary using ethinyl estradiol inhibiting FSH release, or down-regulation of hypothalamic-pituitary stimulation of FSH production by using gonadotropin releasing hormone agonists or antagonists.","PeriodicalId":147903,"journal":{"name":"Gynecology & Reproductive Health","volume":"22 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-08-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121749585","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
L. Zalles, Kyle Le, J. Check, C. Wilson, D. Summers, J. Choe
{"title":"The Impact of State Mandated Financial Coverage for Donor Egg In Vitro Fertilization (IVF) Cycles on Choosing Fresh Eggs from Infertile Donor vs. Paid Donors vs. Frozen Egg Banks","authors":"L. Zalles, Kyle Le, J. Check, C. Wilson, D. Summers, J. Choe","doi":"10.33425/2639-9342.1196","DOIUrl":"https://doi.org/10.33425/2639-9342.1196","url":null,"abstract":"We sought to determine if using infertile oocyte donors donating only half of the eggs collected to recipients, had comparable live delivery rates following fresh and frozen embryo transfer (ET) when compared to oocytes obtained from compensated donors with a single recipient, compensated donors split between two recipients, or an oocyte bank. A retrospective review of 1,361 in vitro fertilization-embryo transfer (IVF-ET) cycles comparing live delivery rates after fresh ET and live delivery rates per retrieval by donor oocyte source was performed. Live delivery rates per fresh ET showed no significant difference between the four-oocyte sources. However, using an infertile donor had a statistically significant increase in live delivery rate per retrieval when compared to using a compensated donor split between two recipients or an oocyte bank. There was a 15% decrease in live delivery rate per retrieval when using an infertile donor compared to a compensated donor with a single recipient. Financial burden of infertility services has been a long-standing barrier to infertility treatment access. Sharing oocytes with an infertile donor can have financial advantage without significant sacrifice of success rates. It is especially cost saving for recipients in mandated states who actually are financially reimbursed for the majority of the cost of the IVF cycle.","PeriodicalId":147903,"journal":{"name":"Gynecology & Reproductive Health","volume":"60 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-08-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115672376","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Idiopathic Peripheral Facial Palsy and Preclampsia: A Case Report","authors":"J. M, H. S, I. K, W. O, L. A, B. S","doi":"10.33425/2639-9342.1187","DOIUrl":"https://doi.org/10.33425/2639-9342.1187","url":null,"abstract":"During pregnancy, pre-eclampsia can be associated to idiopathic peripheral facial nerve palsy. It can be explained by similar physiopathological mechanisms. Facial palsy usually appears during the third trimester of pregnancy or in the early postpartum period. The prognosis is generally good and is not affected by the pregnancy. The occurrence of peripheral facial palsy during pregnancy should alert the obstetrician to look for a possible pre-eclampsia. We report a case of a patient with pre-eclampsia who developed idiopathic peripheral facial palsy during the third semester of pregnancy. Evolution was favorable, following treatment combining anti-hypertensive medication, corticosteroid therapy and ophthalmologic care.","PeriodicalId":147903,"journal":{"name":"Gynecology & Reproductive Health","volume":"27 10","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132791182","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Incidence, Characteristics, Maternal and Perinatal Outcomes of HELLP Syndrome","authors":"Z. Kali, F. Çağıran, P. Kırıcı, M. Meydanlı","doi":"10.33425/2639-9342.1190","DOIUrl":"https://doi.org/10.33425/2639-9342.1190","url":null,"abstract":"Objective: HELLP syndrome is associated with increased maternal and fetal complications. It was aimed to provide the incidence of HELLP syndrome and related maternal and neonatal mortality and morbidity. Patients and Methods: Patients diagnosed with HELLP Syndrome within the study period were subsequently assessed in this retrospective study of a 5-years period. Primary outcome was to establish the incidence of HELLP syndrome and to investigate the predicting factors for adverse maternal and fetal outcomes. Secondary outcome was to evaluate the factors related with disseminated intravascular coagulation (DIC). The diagnosis of HELLP syndrome was established with using the Sibai criteria. Results: A total of 12.324 women gave birth during the study period. One hundred four pregnant women were diagnosed with HELLP syndrome with an incidence of 0.84%.The rate of maternal mortality was 2.9% (n=3).Out of all, 86.5% (n=90) of the patients had at least one major complication following the birth. Out of all, 60.6% (n=63) of the neonates had at least one major complication following the birth. The rate of prematurity and IUGR was 61.5% (n=64) and 28.2% (n=29), respectively. There were 3 (2.8%) neonatal deaths. The stillbirth rate was 18.3% (n=19). Conclusion: HELLP syndrome is a serious clinical condition with an incidence of 8.4 per 1,000 deliveries and result in high maternal mortality and morbidity. The lack of a sufficient antenatal follow-up and the rural residence of pregnant women were found to be related with major maternal adverse outcomes.","PeriodicalId":147903,"journal":{"name":"Gynecology & Reproductive Health","volume":"12 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126160635","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ogbonna Brian O, Ezenne Amara, Okpalanma Nneoma N, O. I, Maduekwe Hilda N, Okoye Ifunanya L, Ejie Loveth I, O. Amala, O. G, Nnamani Monica N, Maduka Anthony O, Ovwighose Samuel O, Njideka Ifeoma Ani, Ugwu Agatha Adaora, M. Anetoh, Ajagu Nnenna
{"title":"Determinants of Intermittent Preventive Malaria Therapy Among Pregnant Women in A Nigerian Teaching Hospital","authors":"Ogbonna Brian O, Ezenne Amara, Okpalanma Nneoma N, O. I, Maduekwe Hilda N, Okoye Ifunanya L, Ejie Loveth I, O. Amala, O. G, Nnamani Monica N, Maduka Anthony O, Ovwighose Samuel O, Njideka Ifeoma Ani, Ugwu Agatha Adaora, M. Anetoh, Ajagu Nnenna","doi":"10.33425/2639-9342.1189","DOIUrl":"https://doi.org/10.33425/2639-9342.1189","url":null,"abstract":"Background: Intermittent Preventive Treatment of malaria in Pregnancy (IPTp) is mostly issued in most antenatal clinics across the country but there have been reports of poor utilization of this prophylaxis. Objective: This study assessed the determinants of IPTp among pregnant women attending a tertiary hospital in southeast Nigeria. Methods: The study was a descriptive cross-sectional study in which a self-administered questionnaire was distributed to 250 pregnant women receiving antenatal care in the study hospital. The data collected were analyzed with the aid of SPSS, using descriptive and inferential statistics. A p-value of less than 0.05 was considered significant. Results: A majority of the participants responded positively to most of the factors assessed, however, none was statistically significant. Conclusion: Based on these findings, pregnant women at a tertiary hospital in southeast Nigeria are aware of IPTp, nevertheless, most fail to commence the medication at the correct time.","PeriodicalId":147903,"journal":{"name":"Gynecology & Reproductive Health","volume":"15 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125591898","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Veronique Tognifode, Djima Patrice Dangbemey, R. Atade, Ruth Mfoumou, Simon Azonbakin, M. Aboubakar, M. Ogoudjobi, C. Tshabu-Aguemon, B. Hounkpatin, J. Denakpo
{"title":"Spontaneous Fertility after Myomectomy for Pregnancy Desire in Reference University Maternities of Benin from 2016 to 2020: Contributing Factors and Pregnancies Outcome","authors":"Veronique Tognifode, Djima Patrice Dangbemey, R. Atade, Ruth Mfoumou, Simon Azonbakin, M. Aboubakar, M. Ogoudjobi, C. Tshabu-Aguemon, B. Hounkpatin, J. Denakpo","doi":"10.33425/2639-9342.1186","DOIUrl":"https://doi.org/10.33425/2639-9342.1186","url":null,"abstract":"Introduction: Spontaneous fertility after myomectomy for pregnancy desire remains a concern. Objective: Appreciate spontaneous fertility after a myomectomy for pregnancy desire. Methods: This was a descriptive and analytical study to collect retrospective data on cases of myomectomy pregnancy desire realised between 2016 and 2020 in the university maternity wards of Cotonou. All myomectomy records for desire for pregnancy were identified. The post myomectomie fertility related data and the clinical characteristics influencing the occurrence of pregnancy and its outcome after myomectomy were analyzed with regard to the rules of professional conduct and ethics. Results: On 188 myomectomies performed for desire of pregnancy, 102 had been analyzed. The mean age was 34 years ± 5.7. Nulligest and nulliparous were the most numerous in the respective proportions of 39.2% and 71.6%, and 16.7% (n=17) had a history of polymyomectomy. Fertility after myomectomy was observed in 16.7% (n=17) of cases. The mean time to return to fertility (pregnancy) after myomectomy was 27 months. Alcohol addiction (p=0.00), gestality (p=0.01), myoma size (p=0.00) and adenomyosis (p=0.00) had an negative impact on the time to onset pregnancy after myomectomy. Of 17 pregnancies recorded after myomectomy, 11 (64.7%) progressed normally with term delivery and 5 spontaneous abortions (29.4%) were recorded. One (1) pregnancy was ongoing at the time of the survey. Planned caesarean section (n=9) was the most frequent mode of delivery. Eleven (11) newborns were welcomed and the diaper suites were simple. Conclusion: Spontaneous fertility after myomectomy remains low in our series. Factors with a negative impact on fertility must be taken into account.","PeriodicalId":147903,"journal":{"name":"Gynecology & Reproductive Health","volume":"28 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130646621","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Vitamin D Supplementation Improves Follicle Maturation By Regulating Oxidant/Antioxidant Balance in Women With PCOS","authors":"M. Ağar, Murat Onal","doi":"10.33425/2639-9342.1188","DOIUrl":"https://doi.org/10.33425/2639-9342.1188","url":null,"abstract":"Objective: To investigate the effect of vitamin D (VD) supplementation on follicular fluid total oxidant status (TOS) and total antioxidant status (TAS) in women undergoing IVF/ICSI due to PCOS. Materials and Methods: Forty infertile women who were diagnosed with PCOS and decided on IVF/ICSI and whose serum VD levels were lower than 20 ng/mL were included in the study. The VD levels of the patients were determined according to the proposal of Endocrine Society. The patients were divided into two equal groups with 20 patients in each group. While the patients in Group 1 were given 400 IU/day of oral VD3 replacement, the patients in Group 2 were given 600 IU/day of oral VD3. VD treatment was started one month before the controlled ovarian stimulation cycle and continued throughout the following cycle. Fifteen patients with serum VD levels >30 ng/mL were taken as the control group. Oral VD replacement was not given to the patients in the control group. TAS and TOS values were measured in the follicle fluids taken from the patients in the VD replacement group and the patients in the control group on the day of ooist pick-up. Results: When compared with the control group, the follicular fluid TAS levels of both groups with VD replacement were significantly higher, while TOS levels were found to be significantly lower. When 400 IU/day VD replacement and 600 IU/day VD replacement were compared within themselves, follicular fluid TAS and TOS levels were found to be similar. Increasing the VD replacement dose from 400 IU/day to 600 IU/day did not cause a significant change in TAS and TOS values. A positive and significant correlation was found between intrafollicular TAS levels and serum VD, MII oocyte, 2PN zygote and clinical pregnancy rates. A negative correlation was found between intrafollicular TOS levels and serum VD, 2PN zygote and clinical pregnancy rates. Conclusions: VD replacement therapy contributes to follicle maturation by regulating intrafollicular oxidant/ antioxidant balance in PCOS patients.","PeriodicalId":147903,"journal":{"name":"Gynecology & Reproductive Health","volume":"104 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123214285","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A. Sissoko, I. Téguété, S. Fané, A. Bocoum, Mohamed Yaya Djire, Moussa Arouna Bagayoko, Amose Kodio, S. Diarra, Amadou Fomba, T. Théra, Y. Traoré, Niani Moukoro
{"title":"Interest in the Classification of Caesarean Section According to Robson at Teaching Hospital GABRIEL TOURE at Bamako, Mali","authors":"A. Sissoko, I. Téguété, S. Fané, A. Bocoum, Mohamed Yaya Djire, Moussa Arouna Bagayoko, Amose Kodio, S. Diarra, Amadou Fomba, T. Théra, Y. Traoré, Niani Moukoro","doi":"10.33425/2639-9342.1191","DOIUrl":"https://doi.org/10.33425/2639-9342.1191","url":null,"abstract":"Caesarean section rates (CSR) are steadily increasing worldwide with levels exceeding the maximum recommended by the WHO. To identify factors that may contribute to the improvement of CSR and to ensure an audit and feedback mechanism, we conducted this study of C-section according to Robson’s classification that identifies 10 mutually exclusive groups based on obstetric characteristics. This was a cross-sectional study from January 1, 2003 to December 31, 2013 on parturients who gave birth in the obstetrics department of the Gabriel TOURE University Teaching Hospital (UTH), which is a 3rd level health structure. We recorded 28,376 deliveries with 9,509 cases of C-section, with a rate of 33.5% (9,509/28,376). Robson's classes 3, 1, 5 and 10 constituted the largest populations and were the greatest contributors to the overall CSR with 7.6%, 7.4%, 5.9% and 5.4% respectively. The emergency admission (evacuation) rate was particularly high among Robson classes 5 and 3 with 57.1% and 46.6% of parturients evacuated, respectively. Classes 1, 3, and 10 had the highest number of cases and indications for emergency C-section. We recorded 298 cases of maternal death or 1.05% (298/28,376) of which 180 or 1.9% (180/9,509) of maternal death related to C-section, it was higher in groups 1, 3 and 10 with respectively 17.8%, 26.6% and 31.6% of cases of death. For fetal prognosis, the overall rate of stillbirth by C-section was 9.2% and was worse in groups 10, 7, 3 and 4 with 23.2%, 10.7%, 9.8% and 9.2% of stillbirths respectively. The stillbirth rate was higher in classes 9 and 10.","PeriodicalId":147903,"journal":{"name":"Gynecology & Reproductive Health","volume":"105 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128599974","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Accessibility and Utilization of Adolescent Sexual and Reproductive Health Services Among Undergraduate Students","authors":"C. Agwuncha, M. Akinwaare","doi":"10.33425/2639-9342.1184","DOIUrl":"https://doi.org/10.33425/2639-9342.1184","url":null,"abstract":"Background: Young people's reproductive health services have been largely neglected in the past, leaving them vulnerable to reproductive health problems like Sexually Transmitted Infections (STIs), unintended pregnancy, unsafe abortion and other harmful practices. Although studies have been done on Adolescent Sexual and Reproductive Health, a persistence of reproductive health problems among undergraduates in Nigeria, especially in the Universities necessitated this study. Methods: The study utilized a descriptive cross-sectional design involving 357 students of randomly selected faculties in the university of Ibadan. A self-administered semi-structured questionnaire was used to assess the accessibility and utilization of Sexual and Reproductive Health Services (SRHSs) among the students. Statistical analysis of data was done using IBM-SPSS version 21.0 software, associations and differences were then tested using Pearson’s correlation test (with significance set at P≤ 0.05), while descriptive data were presented in frequency & percentages. Results: The study found that 70.8% of the respondents have high access to SRHSs, while more than 67.3% underutilized those services. Attitudes of staff in the clinic, religion, cultural practices, longer waiting periods, and lack of privacy were all identified as factors that negatively affect the accessibility and utilization of SRHS. Gender (p=.012), and Accessibility (p=.000) were found to be significantly associated with Utilization of SRHSs. Conclusion: Despite high accessibility, most students still do not utilize available SRHSs. To ensure that young people have access to sexual and reproductive health care in all nursing practice sites, nurses need to gain the knowledge and hone the skills required to deliver evidence based counseling and services to adolescents.","PeriodicalId":147903,"journal":{"name":"Gynecology & Reproductive Health","volume":"54 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116943954","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}